[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Queen Fabiola Children's University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":79},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":34,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100537672","physiologically-based-cord-clamping-to-improve-neonatal-outcomes-in-moderate-and-late-preterm-newborns-100537672",false,"NCT06280872","Physiologically Based Cord Clamping To Improve Neonatal Outcomes In Moderate And Late Preterm Newborns","Prospective Unblinded Randomized Controlled Study Assessing the Physiologically Based Cord Clamping on Ventilation Duration in Moderate and Late Preterm","PhyCordPrem","Inclusion Criteria:\n\nPregnant women followed-up in Brugmann University Hospital will be eligible to participate if:\n\n* The delivery takes place between 32 0\u002F7 and 36 6\u002F7 weeks of gestation\n* They carry singletons\n\nExclusion Criteria:\n\n* Fetal anomalies including congenital malformations, anemia, and growth restriction with abnormal Dopplers.\n* Abnormal placentation such as placenta previa.\n* Signs of fetal distress necessitating an emergency cesarean section.\n* Maternal health issue including severe anemia (defined as hemoglobin level \\\u003C 7 g\u002FdL), preeclampsia, and bleeding disorders.\n* Maternal refusal of the use of blood products.\n* General anesthesia for cesarian section.\n* Planned cord blood banking.\n* Total language barrier without possibility of translation","ALL","32 Weeks","36 Weeks",{"count":21,"type":22},180,"ESTIMATED","INTERVENTIONAL",[25],"NA","Before birth, the baby's lungs are filled with fluid and babies do not use the lungs to breathe, as the oxygen comes from the placenta. As delivery approaches, the lungs begin to absorb the fluid. After vaginal delivery, the umbilical cord is clamped and cut after a delay that allows some of the blood in the umbilical cord and placenta to flow back into the baby. Meanwhile, as the baby breathes for the first time, the lungs fill with air and more fluid is pushed out. However, it does not always work out that way.\n\nA baby born prematurely may have breathing problems because of extra fluid staying in the lungs related to the immaturity of the lung structure. Thus, the baby must breathe quicker and harder to get enough oxygen enter into the lungs. The newborn is separated from the mother to provide emergency respiratory support. Although the baby is usually getting better within one or two days, the treatment requires close monitoring, breathing help, and nutritional help as the baby is too tired to suck and swallow milk. Sometimes, the baby cannot recover well and show greater trouble breathing needing intensive care. This further separates the mother and her baby. A possible mean to help the baby to adapt better after a premature birth while staying close to the mother is to delay cord clamping when efficient breathing is established, either spontaneously or after receiving breathing help at birth. In this study, we intend to test this procedure in moderate or late preterm infants and see whether the technique helps the baby to better adapt after birth and to better initiate a deep bond with the mother.",[28,29,30,31,32,33],"Premature Birth","Respiratory Distress Syndrome in Premature Infant","Sepsis","Intraventricular Hemorrhage of Prematurity","Bronchodysplasia","Jaundice",[35,36,37,38],"Moderate and late preterm newborn","Neonatal respiratory morbidity","Physiological based-cord clamping","Mother-infant bonding","RECRUITING","2024-03-01",{"date":42,"type":43},"2024-03-05","ACTUAL",{"date":45,"type":43},"2024-02-19",{"date":47,"type":22},"2026-07",{"name":49,"class":50},"Queen Fabiola Children's University Hospital","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":17,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},"100301368","registry-on-obesity-surgery-in-adolescents-100301368","NCT03203161","Registry on Obesity Surgery in Adolescents","A Prospective Observational Cohort Study Collecting Coordinated Clinical, Epidemiological, and Behavioural Data to Assess Safety and Efficacy of Surgical Treatment in Adolescent Morbid Obese Patients","ROSA","Inclusion Criteria:\n\n* BMI (or projected BMI) \\> 40 kg\u002Fm² (projected BMI = weight over the age- and gender-specific BMI z-score defined as severe obesity corresponding at a projected BMI of 40 at the age of 18y) OR\n* BMI ((or projected BMI) \\> 35 kg\u002Fm² (projected BMI = weight over the age- and gender-specific BMI z-score defined as severe obesity corresponding at a projected BMI of 35 at the age of 18y) + 1 or more of the following obesity-related comorbid conditions: Obstructive Sleep Apnea Syndrome, Non-alcoholic steatohepatitis, type 2 diabetes, hypertension, benign intracranial hypertension.\n* Minimum 6 months of organized weight loss attempts before surgery (multidisciplinary follow-up)\n* Completed most of their linear growth (Tanner stage ≥ IV, bone age ≥ 13 years in girls and ≥ 14 years in boys assessed by the Tanner and Whitehouse method)\n* Capability and willingness to adhere to postoperative guidelines and prolonged surveillance\n* Informed Consent Form (ICF) signed by patient and parents (or legal guardian)\n\nExclusion Criteria:\n\n* psychological\u002Fpsychiatric disorders that are decompensated or not efficiently treated\n* severe and unstable eating disorders (e.g. binge-eating)\n* signs of addictions or addictive behavior (alcohol or substance abuse)\n* pregnancy or breastfeeding\n* life-threatening multisystem organ failure\n* uncontrolled or metastatic malignancy\n* uncontrolled HIV infection\n* hypercarbic respiratory failure\n* active systemic infection or untreated endocrine dysfunction\n* diseases threatening in the short term or lack of care (self-care or access to family or social support)\n* medically correctable causes of obesity","12 Years","17 Years",{"count":62,"type":22},50,"OBSERVATIONAL","While bariatric surgery is established as a safe and effective alternative with well-defined risks for severely obese adults, little has been published on its use in children.\n\nThere are many unresolved questions concerning the long-term metabolic and psychological consequences of bariatric surgery in adolescents, and the difference with the adult population. The appropriate timing for bariatric surgery in young people, and the predictors of success and safety still need to be determined.\n\nThe aim of this long-term prospective study is therefore to establish the safety and efficacy profile of surgical procedures and to clarify whether reductions in morbidity and mortality outweigh the risks of serious surgical complications and lifelong nutritional deficiencies.",[66,67,68],"Morbid Obesity","Bariatric Surgery","Adolescent Obesity","NOT_YET_RECRUITING","2019-02-11",{"date":72,"type":43},"2019-02-12",{"date":74,"type":22},"2019-09",{"date":76,"type":22},"2029-09",{"name":49,"class":50},3,""]