[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"RTI International\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":401},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,52,88,111,138,162,191,217,250,280,306,332,355,382],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100644248","the-comprehensive-adherence-resource-and-empowerment-support-cares-study-100644248",false,"NCT07666139","The 'Comprehensive Adherence Resource and Empowerment Support' (CARES) Study","Adapting the 'Comprehensive Adherence Resource and Empowerment Support' Intervention for Multiple PrEP Methods Among Adolescent Girls and Young Women in South Africa and Zimbabwe","CARES","Aim 2:\n\nInclusion (AGYW):\n\n* age 16-24 years (in Zimbabwe, participants aged 16 to 17 years must meet the legal criteria for emancipation to be eligible)\n* has initiated PrEP during the study, or no more than 6 months before the study initiation date (for LEN PrEP), or no more than 3 months before the study initiation date (for oral, ring, or CAB PrEP), and\n* willing and able to provide written informed consent for access to medical records, or assent and parental consent if applicable\n* fluent in one of the study languages (English, isiXhosa, Shona, Ndebele)\n* target date for PrEP resupply (i.e., to ensure continued coverage) falls within the month.",true,"FEMALE","16 Years","24 Years",{"count":22,"type":23},2100,"ESTIMATED","INTERVENTIONAL",[26],"NA","The primary aim of this study is to adapt the Comprehensive Adherence Resource and Empowerment Support (CARES) intervention to support adolescent girls and young women (AGYW) aged 16-24 in Zimbabwe and South Africa in effectively using various forms of pre-exposure prophylaxis (PrEP), specifically oral, ring, and injectable PrEP. Originally developed for a clinical trial setting, CARES has shown promising results in enhancing effective PrEP use through a structured mix of counseling, SMS\u002Fphone calls, and peer support for daily oral PrEP and the PrEP ring. However, its resource-intensive design requires adaptation for routine public health settings to ensure feasibility, fidelity, acceptability, and effectiveness. This adapted intervention will be tailored with input from AGYW, PrEP providers, and local stakeholders to support sustainable PrEP use and address HIV prevention needs among AGYW. Additionally, it will incorporate injectable PrEP and be modified to suit routine public health contexts. Once the components are finalized, the adapted CARES intervention will be evaluated for effectiveness, feasibility, fidelity, and acceptability.",[29],"HIV",[31,32,33,34,35,36,37,38],"PrEP","AGYW","South Africa","Zimbabwe","Effectiveness","Feasibility","Acceptability","Fidelity","NOT_YET_RECRUITING","2026-06-23",{"date":42,"type":43},"2026-06-26","ACTUAL",{"date":45,"type":23},"2026-07-01",{"date":47,"type":23},"2028-10-31",{"name":49,"class":50},"RTI International","OTHER",2,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":71,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},"100575899","transition-health-and-resilience-through-valued-experiences-thrive-pilot-for-newly-separated-veterans-100575899","NCT06778278","Transition Health and Resilience Through Valued Experiences (THRiVE) Pilot for Newly Separated Veterans","Adapting Behavioral Activation to Improve Mental Health Outcomes and Reduce Suicide Risk During the Military Transition","Inclusion Criteria:\n\n* Be either (a) a United States military veteran who separated no more than 12 months prior to study enrollment or (b) a United States transitioning service member on terminal leave\n* Be at least 18 years old\n* Have access to the internet; a desktop computer, laptop, tablet, or other \"smart\" device with video camera, speakers, and microphone; and a private place from which to attend THRiVE sessions\n* Reside and complete all study activities within the United States\n\nExclusion Criteria:\n\n* Endorse lifetime manic, hypomanic, or psychotic episodes\n* Meet Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria for current severe alcohol use disorder or substance use disorder (except for tobacco use disorder, which will not be exclusionary)\n* Screen positive for moderate or high acute risk for suicide\n* Screen positive for more than minimal risk for other-directed violence\n* Are receiving or plan to receive BA therapy for any mental health condition between enrollment and the 3-month follow-up assessment","ALL","18 Years",{"count":62,"type":23},40,[26],"The objective of this study is to develop and pilot a program designed to improve mental health outcomes and reduce suicide risk during the transition from military to civilian life. It is hypothesized that the Transition Health and Resilience through Valued Experiences (THRiVE) program, to be developed as part of this study, will meet participant recruitment, retention, and satisfaction benchmarks (primary outcomes) and show positive preliminary effects on mental health symptoms, risk factors for suicidal ideation, and psychosocial functioning outcomes (secondary outcomes).\n\nThe specific aims of this study are to:\n\n1. Develop a small-group, peer-led, cross-cutting prevention program for newly separated veterans (NSVs) called THRiVE and\n2. Evaluate the feasibility, acceptability, and preliminary effects of the THRiVE program on mental health symptoms, risk factors for suicidal ideation, and psychosocial functioning outcomes.\n\nUp to 40 NSVs participating in this Stage 1 pilot study will complete validated self-report measures at baseline, immediately after completing the THRiVE program (post-THRiVE), and 3 months after completing the THRiVE program (follow-up). The duration of a participant's time in the study is anticipated to be 5 months.",[66,67,68,69,70],"Military Transition","Community Reintegration","Mental Health","Suicidal Ideation","Alcohol Misuse",[72,73,74,75,76,77],"Military transition","Community reintegration","Mental health","Suicidal ideation","Transitioning Service Members","Newly separated Veterans","RECRUITING","2026-06-08",{"date":81,"type":43},"2026-06-10",{"date":83,"type":43},"2025-07-30",{"date":85,"type":23},"2026-10-31",{"name":49,"class":50},1,{"id":89,"slug":90,"hasResults":11,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":4,"eligibilityCriteria":94,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":24,"phases":97,"briefSummary":98,"conditions":99,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":5},"100493169","nutrition-for-precision-health-powered-by-the-all-of-us-100493169","NCT05701657","Nutrition for Precision Health, Powered by the All of Us","Nutrition for Precision Health, Powered by the All of Us Research Program","Inclusion Criteria:\n\n* Overall Inclusion -- Participants 18 years of age or older who have completed the primary All of Us consent process, Electronic Health Record consent process, have provided at least one All of Us biospecimen suitable for DNA sequencing, and have completed All of Us Participant Provided Information (PPI) Modules 1-3 (Basics, Overall Health, and Lifestyle); Speak English or Spanish; Able and willing to comply with study requirements and consent to participate.\n* Module 1 -- Must be willing and able to comply with Module 1 protocol; Must provide informed consent for Module 1.\n* Module 2 -- Must have completed Module 1; Must provide informed consent for Module 2; Must agree to comply with protocol over a period of approximately 10 to 12 weeks and up to six months. This includes consuming only the foods provided during periods of controlled feeding. Module 2 has three controlled feeding periods each lasting approximately two weeks with at least two weeks between feeding periods, and up to 6 months allowed for completion of the Module.\n* Module 3 -- Must have completed Module 1; Must provide informed consent for Module 3; Must agree to comply with protocol over a period of approximately 10 to 12 weeks and up to 6 months. This includes being domiciled three times, for two weeks each, and consuming only the foods provided during the domiciled periods. There is at least two weeks between domiciled periods, and up to 6 months allowed for completion of the Module.\n\nExclusion Criteria:\n\n* Module 1\n\n  1. Any change to the participant's status from the time of All of Us enrollment that would render them ineligible for All of Us (e.g., being incarcerated, no longer living in the United States, or withdrawn from that study).\n  2. Inability to provide informed consent and engage in informed consent procedures\n  3. Participants who suffer from allergic reactions to, or are unwilling to consume, any components of the liquid mixed meal (e.g., milk products, soy products)\n  4. Barriers to safe insertion of peripheral IV canula:\n\n     1. Contraindications to peripheral IV canula insertion such as local skin infection, inflammation, trauma or burns if all the upper extremities were involved and there is no unaffected extremity available for IV placement; or\n     2. A need for long-term IV access (e.g., ESRD); or\n     3. Lymphedema or deep vein thrombosis (DVT) in the extremity of the IV (in the case where another extremity is not available); or\n     4. Coagulopathy requiring blood thinning products; or\n     5. Arteriovenous (AV) graft or fistula in the extremity of the IV (in the case where another extremity is not available)\n  5. Pregnancy-related conditions:\n\n     1. Gestational age precluding completion of the Module by 36 weeks. A pregnant participant should complete visit 1 by gestational age 34 weeks, 0 days and complete Module 1 by week 36.\n     2. Severe morning sickness limiting mixed meal tolerance test (MMTT) consumption\n  6. Certain types of disease states:\n\n     1. Dumping syndrome or inability to consume the volume of the MMTT liquid\n     2. Severe malabsorption such as history of short gut syndrome or need for parenteral or enteral nutrition\n     3. Less than 12-months post-metabolic or bariatric surgery\n     4. History of chronic pancreatitis (e.g., Cystic fibrosis) complicated by inability to tolerate the volume of the MMTT liquid\n     5. Health conditions requiring chronic blood transfusions or iron infusions\n     6. Hemoglobin \\\u003C9.5 g\u002FdL at screening\n  7. Serious illness and in hospice or palliative care for terminal disease\n  8. Swallowing issues:\n\n     1. Self-reported difficulty tolerating solids or liquids\n     2. Aspiration risks that require change in thickness of liquid or dietary modifications\n  9. Short term antibiotic use. For example, active antibiotics use for an ongoing acute infection\n  10. Blood donation in the last 3 months\n  11. GLP-1 agonist medication (e.g. Semaglutide) instability as defined by less than 3 months of continuous use\n  12. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's and\u002For team's opinion jeopardizes the safety of the participant or others or would interfere with adherence to the protocol.\n* Module 2\n\n  1. Any change to the participant's status from the time of All of Us enrollment that would render them ineligible for All of Us (e.g., being incarcerated, no longer living in the United States, or withdrawn from that study)\n  2. All the above mentioned exclusion criteria for Module 1 (except inability to consume components of the liquid mixed meal)\n  3. Inability to provide informed consent and engage in informed consent procedures\n  4. Inability or failure to complete all critical elements from Module 1 (dietary, physical activity and sleep assessments, continuous glucose monitoring, MMTT)\n  5. Participants who are already enrolled in Module 3\n  6. Participants who are unlikely to be able to adhere to the protocol, based on structured adherence assessment by a study registered dietitian or other trained staff. This includes participants who have known allergic reactions to, or unwillingness to consume, study foods in Module 2 (e.g., gluten, meat, fish, nuts, dairy products) that cannot be reasonably accommodated by the metabolic kitchen within allowable criteria for the test diets.\n  7. Participants who plan to relocate to an area not served by NPH or travel plans that do not permit completion of the Module over a period of up to 6 months.\n  8. Pregnancy-related conditions:\n\n     1. Gestational age precluding completion of the Module by week 36. A pregnant participant must be able to begin the first diet by gestational age 26 weeks, 0 days and complete the Module by week 36.\n     2. High risk pregnancy defined as fetal anomaly, gestational hypertension (SBP \\>140 mmHg and DBP \\>90 mmHg), pre-eclampsia, or gestational diabetes mellitus\n  9. Possible ethanol (alcohol) use disorder defined by Alcohol Use Disorders Identification Test (AUDIT) score of \\>15\n  10. History of surgery for the treatment of obesity and:\n\n      1. Self-reported dumping syndrome; or\n      2. Following a special diet prescribed by their practitioner\n  11. Uncontrolled disease states:\n\n      1. Hypertension \\>160\u002F100mmHg\n      2. Exacerbation of underlying gastrointestinal disease, including inflammatory bowel disease or other malabsorptive disorders\n      3. Decompensated cirrhosis\n      4. Previously diagnosed diabetes Mellitus with HbA1c \\>12% at screening\n      5. Newly diagnosed diabetes within the past three months, or HbA1c \\>6.5% at screening in a person not previously diagnosed with diabetes.\n  12. Participants with a history of end-stage renal disease (ESRD) on hemodialysis\n  13. Active infectious diseases (e.g., active tuberculosis \\\u003C 3 months from symptom onset or positive test, COVID \\\u003C 1 month from symptom onset or positive test)\n  14. Malignancy (e.g., cancer) actively receiving cytotoxic chemotherapy (oral or infusions) treatment except for nonmelanoma skin cancers during the study period\n  15. Participants who require dietary restrictions due to a medical condition or are on a prescribed diet for underlying chronic diseases\n  16. Participants with type 1 or type 2 diabetes on insulin\n  17. Participants aged ≥ 75 years with type 2 diabetes taking prescribed medications that can cause hypoglycemia (e.g. sulfonylureas, glinides), or on a prescribed diet\n  18. Hospitalization for a chronic disease (e.g., congestive heart failure, stroke) within the past three months\n  19. Requiring transfusions\u002Fapheresis during study period\n  20. Participants with a current diagnosis of, or who have received treatment for, bulimia or anorexia nervosa within the past 3 years\n  21. Participants with major psychiatric disorders, including major depression, schizophrenia, or psychosis, who have been hospitalized in the past six (6) months or are currently enrolled in treatment programs\n  22. Hemoglobin \\\u003C9.5 g\u002FdL at screening\n  23. Myocardial infarction, invasive cardiac procedure, participation in a cardiac or acute rehabilitation programs, transient ischemic attacks, or unstable arrhythmias within the past 3 months\n  24. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's opinion, might jeopardize the safety of the participant or others, or be expected to interfere with adherence to the protocol.\n* Module 3\n\n  1. All the above mentioned exclusion criteria for Modules 1 and 2\n  2. Participants who are already enrolled in Module 2\n  3. Any disorder, unwillingness, or inability not covered by any other exclusion criteria which, in the investigator's opinion, might jeopardize the safety of the participant or others, or would interfere with adherence to the protocol\n  4. Inability to abstain from tobacco or nicotine use, vaping, alcohol, illicit drug use, or recreational drug use for two (2) consecutive weeks while domiciled in the clinical unit. Nicotine gum, pouch, or patch are permitted.\n  5. Any condition requiring in-person treatments or visits during the study period. This will not be accommodated by the domiciling protocol; however, tele-health visits with the participants regular doctor are permitted.\n  6. Lactation or other infant care needs that cannot be accommodated while domiciled in the clinical unit\n  7. Depression as assessed by:\n\n     1. Patient Health Questionnaire (PHQ-9) score ≥ 15; or\n     2. Affirmative answer to PHQ-9 suicidality question: \"Thoughts that you would be better off dead or of hurting yourself in some way\"\n  8. Unable to engage in daily self-care activities (e.g., bathing, transferring, toileting, feeding, dressing)\n  9. Uncontrolled endocrine disorders (such as Cushing's disease, pituitary disorders, diabetes)\n  10. Uncontrolled pain requiring frequent or daily treatment, or adjustment of medication requiring weekly or bi-weekly visits. Pain medications used on an as-needed basis (PRN), such as acetaminophen or NSAIDs, are not excluded.\n  11. Chronic prescription medications that would pose logistical and safety issues for participation",{"count":96,"type":23},8000,[26],"The goal of this Nutrition for Precision Health (NPH) powered by All of Us research study is to develop Artificial Intelligence\u002FMachine Learning (AI\u002FML) algorithms that predict individual responses to diet patterns using rich multimodal data streams collected across multiple domains (e.g., behavior, social, environmental, clinical and molecular biomarkers). NPH includes a large phenotyping cohort (Module 1, N=8000) and two separate follow-up groups drawn from a subset of Module 1participants. One group (Module 2, N=1200) receives three distinct diets in a 14-day crossover sequence, with at least a 14-day washout period between diets, while living in their own homes. A second group (Module 3, N=150) receives the same three diets under full-time supervision in a residential research setting. We will train and test AI\u002FML models to predict 0-4 hour postprandial response curves for glucose, insulin, triglycerides, and GLP-1, to the standardized diet-specific meal test (DSMT) collected after each of the three different diets delivered in Module 2. Each diet functions as a controlled stimulus to reveal biological features (such as individual variables, patterns, or clusters of measurements) that best predict a person's response.\n\nThe Module 2 DSMT response curves are the primary outcomes (dependent variables) for AI\u002FML algorithms that predict individual responses to diet patterns.\n\nAs a secondary objective, NPH will evaluate the validity and acceptability of technology-based dietary assessment tools. The Automated Self-Administered 24-hour recall (ASA24), Automatic Ingestion Monitor-2 (AIM-2), and the mobile food record (mFR) will be evaluated in Modules 2 and 3, and the ASA24 food record and the image-assisted ASA24 recall will be evaluated only in Module 3. Total energy intake, macronutrient and dietary fiber intake data are the main outcomes for validity testing compared against measures of actual intake. Acceptability will be determined from feedback surveys.",[100,101,102],"Nutrition","Health","Dietary Habits","2026-06-01",{"date":105,"type":43},"2026-06-03",{"date":107,"type":43},"2023-04-14",{"date":109,"type":23},"2027-01-31",{"name":49,"class":50},{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":59,"minAge":4,"maxAge":4,"enrollmentInfo":119,"targetDuration":4,"studyType":121,"phases":4,"briefSummary":122,"conditions":123,"keywords":127,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":129,"lastUpdatePostDateStruct":130,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},"100640774","collaboration-for-down-syndrome-progress-cdp-100640774","NCT07625579","Collaboration for Down Syndrome Progress (CDP)","The INCLUDE (INvestigation of Co-occurring Conditions Across the Lifespan to Understand Down Syndrome) Project's Collaboration for Down Syndrome Progress (CDP) Program","CDP","Inclusion Criteria:\n\n* Individual with Down syndrome\n\nTo be considered potentially eligible for this CDP, a participant must meet the following criteria:\n\n* Diagnosis of Down syndrome (with the exception of control participants for the Subsample study on Imaging). We will be enrolling participants with all types of Down syndrome including standard Trisomy 21, mosaic Down syndrome, and translocations.\n* Primary language is English, Spanish, or Portuguese.\n\nSupport Person\n\n* Able to attend in-person or remote visits.\n* Able to provide accurate information about the study participant's clinical outcomes and family history.\n* Primary language is English, Spanish, or Portuguese.\n\nBiological parent(s) biospecimen collection\n\n* Biological parent of the enrolled participant.\n* Willing to provide a biological sample.\n* Primary language is English, Spanish, or Portuguese. Imaging subsample study controls\n* A subset of controls will be enrolled to match a cohort of individuals who take part in the CDP Subsample Study on imaging. Healthy control infants must be born at greater than 36 weeks gestational age and must have at least one older sibling. The sibling criterion allows comparability for potential analyses combining control data from DS-CDP with analogous control data previously collected by IBIS for other neurodevelopmental studies.\n\nExclusion Criteria:\n\n* A participant will also be excluded if a healthcare professional determines that CDP involvement poses a risk of mental and physical harm to the participant.\n\nImaging subsample study exclusion criteria for individuals with Down syndrome and controls:\n\n* Known genetic conditions or syndromes with effects on neurobehavioral development (except for Down syndrome) such as Fragile X syndrome, Williams syndrome, or Prader-Willi syndrome. We may also exclude other syndromes such as Marfan's syndrome or Turner syndrome because of overall significant multisystem effects.\n* Birth weight \\\u003C 2,000 grams or gestational age \\\u003C 34 weeks (infants with Down syndrome infants) or \\\u003C37 weeks (control subjects)\n* Significant perinatal adversity, in utero neurotoxin exposure or maternal gestational diabetes requiring medication management\n* Significant medical conditions (unrelated to Down syndrome) affecting growth, development, cognition or sensory impairments. We will conduct a review of the medical history to identify major medical conditions that might be a reason for exclusion.\n\n  * Neurological event like a stroke\n  * Congenital infection associated with altered development (e.g., congenital rubella)\n  * Significant infection affecting the brain after birth, like meningitis\n* In infants with Down syndrome, severe medical issues which may exert significant developmental effects beyond Down syndrome such as:\n\n  * Cyanotic cardiac abnormalities (e.g., Tetralogy of Fallot) that affect overall oxygen levels\n  * Frailty because of recovery from significant surgery or extended hospital stays\n* Contraindication for MRI\n* English not predominant home language\n* Family history of a first-degree relative with psychosis or bipolar disorder (controls only)\n* To be consistent with prior imaging studies from the infant brain imaging study, healthy controls will additionally be excluded for a family history of a first- or second-degree relative with ASD to also allow them to serve as a comparison group for elevated familial liability for ASD.\n\nSleep subsample study exclusion criteria:\n\n* Participants under the age of 12 who are currently being treated for obstructive sleep apnea using a positive airway pressure (PAP) device.\n* For the WatchPAT device, participants must weigh more than 65 pounds. They cannot have a permanent pacemaker or sustained non-sinus cardiac arrhythmias.",{"count":120,"type":23},1400,"OBSERVATIONAL","The Collaboration for Down Syndrome Progress (CDP) is a long-term study that follows people with Down syndrome of all ages. The goal is to better understand their health, development, and everyday experiences over time. Participants and their caregivers will answer questions, share medical information, and may give samples like blood or saliva. Some participants may also take part in optional activities such as sleep studies, movement tracking, or brain imaging. By collecting the same types of information at many sites, the CDP will help researchers learn why certain health conditions are more common in people with Down syndrome and how to improve care and quality of life.",[124,125,126],"Down Syndrome","Chromosome Disorders","Intellectual and Developmental Disabilities",[128],"Down syndrome","2026-05-28",{"date":131,"type":43},"2026-06-04",{"date":133,"type":43},"2026-05-01",{"date":135,"type":23},"2029-08-31",{"name":49,"class":50},16,{"id":139,"slug":140,"hasResults":11,"nctId":141,"briefTitle":142,"officialTitle":143,"acronym":144,"eligibilityCriteria":145,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":146,"enrollmentInfo":147,"targetDuration":4,"studyType":24,"phases":149,"briefSummary":150,"conditions":151,"keywords":4,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":154,"lastUpdatePostDateStruct":155,"startDateStruct":157,"completionDateStruct":159,"leadSponsor":161,"locationsCount":87},"100497164","gathering-online-for-dialogue-and-discussion-to-enhance-social-support-100497164","NCT05753683","Gathering Online for Dialogue and Discussion to Enhance Social Support","GODDESS (Gathering Online for Dialogue and Discussion to Enhance Social Support): Engaging Young African American Women in a Virtual Group App to Address Alcohol Misuse, Sexual Risk, and Pre-exposure Prophylaxis (PrEP) in North Carolina (NC)","GODDESS","Selected Inclusion Criteria:\n\n* identify as Black\u002FAfrican American\n* identify as female\n* be between 18 and 30 years old\n* recent substance use\n* HIV negative and not currently on PrEP\n* have an Android or iOS-based smartphone\n\nSelected Exclusion Criteria:\n\n* test positive for HIV\n* participated in the previous study activities of the current study or previous related studies","30 Years",{"count":148,"type":23},500,[26],"The goal of this trial is to test a modified mobile health intervention (with a group component) relative to a mobile health intervention in a two-arm randomized trial with up to 500 young women who are human immunodeficiency virus (HIV)-negative and who misuse alcohol.\n\nThe expected outcomes are to: (1) determine the efficacy of the virtual group component in reducing alcohol use and sexual risk and increasing pre-exposure prophylaxis (PrEP) utilization; and (2) understand selected outcomes for implementation.\n\nParticipants will be randomized to receive either the mHealth app or the mHealth app plus the group component, and followed up at 3- and 6-months post-enrollment.",[70,29,152,153],"Sexually Transmitted Infections","Pre-exposure Prophylaxis","2026-05-15",{"date":156,"type":43},"2026-05-19",{"date":158,"type":43},"2025-04-07",{"date":160,"type":23},"2027-11",{"name":49,"class":50},{"id":163,"slug":164,"hasResults":11,"nctId":165,"briefTitle":166,"officialTitle":166,"acronym":167,"eligibilityCriteria":168,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":169,"targetDuration":4,"studyType":24,"phases":171,"briefSummary":172,"conditions":173,"keywords":174,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":87},"100637769","improving-choice-and-use-of-biomedical-hiv-prevention-for-women-in-uganda-a-couples-based-approach-100637769","NCT07574619","Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach","CUPID","Inclusion Criteria:\n\nAll Aims:\n\n1. Able and willing to provide written informed consent\n2. Fluent in English or the dominant language spoken in the health facility's region.\n\nAim 1:\n\n1. Age ≥18 years\n2. Meets one of the following criteria:\n\n   1. Performs tasks related to PrEP outreach and\u002For delivery in former CATALYST study areas. This may include clinic and non-clinic positions.\n   2. Is a member of one of the three regional CATALYST CABs\n3. Willing to participate in a focus group discussion\n\nAim 2:\n\n1. Aged 18 years or older\n2. Attending a PrEP follow-up visit\n3. Able and willing to complete all study procedures.\n\nAim 3:\n\n1. Age ≥18 years\n2. Meets one of the following criteria:\n\n   1. CUPID couples' decision tool user\n   2. A CUPID intervention provider (member of a CHT or other PrEP Provider)\n   3. A provider offering PrEP choice through a health facility where CUPID is implemented\n   4. MOH or District Health Official\n3. Willing to complete a questionnaire and participate in a qualitative interview (individual or dyadic)\n\nExclusion Criteria:\n\nAll Aims: Participants will be excluded who have any condition that, in the opinion of the MPI or designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.\n\nAim 2:\n\nExclusion criteria: Participants aged 15-17 years",{"count":170,"type":23},1424,[26],"This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics already providing choices for PrEP in Uganda, the investigators will evaluate whether CUPID is effective in increasing PrEP uptake, persistence, and use among Ugandan women and assess implementation outcomes to determine whether it is acceptable and feasible to implement. If successful, CUPID will offer a community-based strategy for engaging male partners to support PrEP choice and improve HIV prevention among women and provide a scalable and sustainable intervention that will contribute to a more comprehensive approach to HIV prevention.",[29],[175,176,177,178,179,180,181,182],"CAB-PrEP","LEN-PrEP","Oral PrEP","PrEP Ring","Uganda","Couples","Decision Tool","PrEP Choice","2026-05-14",{"date":185,"type":43},"2026-05-18",{"date":187,"type":43},"2026-05-13",{"date":189,"type":23},"2028-03",{"name":49,"class":50},{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":197,"eligibilityCriteria":198,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":199,"targetDuration":4,"studyType":24,"phases":201,"briefSummary":202,"conditions":203,"keywords":206,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":216},"100633538","safer-drinking-spaces-study-100633538","NCT07527988","Safer Drinking Spaces Study","Rigorous Evaluation of Training in Alcohol-Serving Venues for Sexual Violence Prevention","SDSS","Inclusion Criteria:\n\n* At least 18 years old\n* Able to read and speak English\n* Employee or patron of participating venues\n\nExclusion Criteria:\n\n* Has any condition that, in the opinion of the PI or their designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.",{"count":200,"type":23},3180,[26],"The goal of this study is to evaluate the active bystander training provided by Safe Bars, Inc. and their local chapter organizations to staff at alcohol-serving establishments (e.g., bars). The training aims to improve norms about violence, create safer environments by teaching staff to intervene in potentially harmful situations, and help prevent sexual violence in the venue community. The study will examine the implementation and effectiveness of the training. The main questions it aims to answer are:\n\n1. Do staff and patrons at venues that have received Safe Bars training experience lower rates of sexual violence at the venue than staff and patrons at venues that have not received the training?\n2. Are staff at venues that have received Safe Bars training more likely to intervene in potentially risky situations than staff at venues that have not received the training?\n3. What characteristics of venue environments and staff and patron beliefs and perceptions are responsible for effects of the training on sexual violence and bystander behavior outcomes?\n4. What characteristics and conditions are necessary for effective Safe Bars implementation and improved staff and patron outcomes?\n\nResearchers will compare staff and patron experiences at venues that have received the training with venues that are offered a delayed training. Staff and patron participants will be asked to complete surveys over about 12 months, research staff will conduct observations of training and observations in the venues, and selected venue managers and staff will be asked to complete individual interviews.",[204,205],"Sexual Violence","Bystander Intervention",[207,208],"alcohol-serving venues","community-level evaluation",{"date":210,"type":43},"2026-05-07",{"date":212,"type":23},"2026-05",{"date":214,"type":23},"2028-12",{"name":49,"class":50},3,{"id":218,"slug":219,"hasResults":11,"nctId":220,"briefTitle":221,"officialTitle":222,"acronym":4,"eligibilityCriteria":223,"healthyVolunteers":17,"sex":59,"minAge":224,"maxAge":4,"enrollmentInfo":225,"targetDuration":4,"studyType":24,"phases":227,"briefSummary":228,"conditions":229,"keywords":232,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":87},"100534228","evaluating-an-adverse-childhood-experience-targeting-advocate-model-of-a-substance-use-prevention-program-100534228","NCT06236100","Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program","Evaluating an Adverse Childhood Experience-Targeting Advocate Model of a Substance Use Prevention Program: A Hybrid Type 1 Effectiveness-Implementation Trial","Inclusion Criteria: To be eligible to participate in this study, a family must meet all of the following criteria:\n\n* Either reside in, or attend SFP meetings, within one of the 36 New Jersey communities with disproportionate levels of ACEs and substance use disorder (SUD) issues that are assigned to either the treatment or control conditions via the study's cluster randomized controlled trial design\n* Meet family eligibility requirements:\n\n  * One or more adult caregivers\n  * One or more adolescents, ages 7 to 17\n* Caregiver provision of signed and dated informed consent form\n* For children, informed assent and parental permission via the informed consent to participate in the study\n* Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study\n* Willingness to adhere to the regimens of the SFP and FA interventions\n* Access to necessary resources for participating in a technology-based intervention (i.e., computer, smart phone, internet access)\n\nExclusion Criteria: A family who meets any of the following criteria will be excluded from participation in this study:\n\n* Caregiver has previously completed SFP with one or more children, ages 7 to 17\n* Intellectual disabilities (i.e., cognitive impairments that would prohibit the completion of the SFP curriculum or data collection instruments)\n* Language difficulties (caregivers and children must read and understand spoken English)","7 Years",{"count":226,"type":23},360,[26],"Primary Objective: Conduct a rigorous evaluation of a prevention-based intervention designed to mitigate the harms of adverse childhood experiences (ACEs) exposure and prevent future ACEs, substance use, and overdose within 36 communities experiencing a disproportionate burden of substance use and ACEs.\n\nThe study has three aims: (1) use a cluster randomized controlled trial to test effectiveness of the Strengthening Families Program (SFP) + Family Advocate (FA) intervention on substance use, overdose, and ACEs in 18 communities compared with SFP-only in 18 communities; (2) conduct a robust process evaluation informed by the Consolidated Framework for Implementation Research (CFIR) to explore implementation barriers and facilitators; and (3) conduct a cost evaluation to accurately estimate the costs required to implement SFP and SFP+FA and assess the cost-effectiveness of SFP+FA relative to SFP alone. Findings will provide a roadmap about the best ways to help disproportionately affected communities prevent substance use, overdose, and ACEs.",[230,231],"Substance-Related Disorders","Adverse Childhood Experiences",[231,233,234,235,236,237,238,239,240,241],"Strengthening Families Program","Family Advocate","Community-level interventions","Hybrid Type 1 Design","Mixed-Method Evaluation","Effectiveness Trial","Cluster Randomized Controlled Trial","Process Evaluation","Cost Evaluation","2026-04-29",{"date":244,"type":43},"2026-05-05",{"date":246,"type":43},"2023-11-29",{"date":248,"type":23},"2027-09-29",{"name":49,"class":50},{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":256,"eligibilityCriteria":257,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":258,"targetDuration":4,"studyType":24,"phases":260,"briefSummary":261,"conditions":262,"keywords":264,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":272,"lastUpdatePostDateStruct":273,"startDateStruct":275,"completionDateStruct":277,"leadSponsor":279,"locationsCount":87},"100609423","producing-outcome-measures-for-otp-quality-improvement-100609423","NCT07214389","PRoducing Outcome Measures for OTP Quality Improvement","Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On: Project 2 - Producing Outcome Measures for OTP Quality Improvement","PROMOTE-QI","Only BayMark OTPs are eligible for participation.",{"count":259,"type":23},4500,[26],"This study tests ways to help opioid treatment programs (OTPs) keep patients in care. Staying on methadone or buprenorphine is linked to better outcomes, yet many people leave treatment early. The project will compare two approaches that provide clinics with retention\u002Foutcome quality measures and a quality-improvement (QI) toolkit-either alone or with added facilitation-against usual care.\n\nForty-five BayMark OTPs in multiple states will be randomly assigned to one of three groups: (1) quality measures + QI toolkit; (2) quality measures + QI toolkit + external QI facilitation; or (3) usual care.\n\nThe primary outcome is 90-day retention in treatment, measured from OTP electronic health records and Medicaid claims. Secondary outcomes include emergency department visits, hospitalizations, overdoses, and mortality. Findings will identify practical, scalable strategies to improve patient retention in OTPs.",[263],"Opioid Use Disorder",[265,266,267,268,269,270,271],"Opioid Treatment Programs (OTPs)","Methadone","Buprenorphine","Quality Improvement (QI)","Treatment Retention","Addiction Services","Implementation Science","2026-04-16",{"date":274,"type":43},"2026-04-21",{"date":276,"type":43},"2025-10-03",{"date":278,"type":23},"2027-12",{"name":49,"class":50},{"id":281,"slug":282,"hasResults":11,"nctId":283,"briefTitle":284,"officialTitle":285,"acronym":4,"eligibilityCriteria":286,"healthyVolunteers":17,"sex":59,"minAge":19,"maxAge":287,"enrollmentInfo":288,"targetDuration":4,"studyType":24,"phases":290,"briefSummary":291,"conditions":292,"keywords":295,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":298,"lastUpdatePostDateStruct":299,"startDateStruct":301,"completionDateStruct":303,"leadSponsor":305,"locationsCount":87},"100610347","virtual-village-for-young-parents-100610347","NCT07226401","Virtual Village for Young Parents","Preventing Intimate Partner Violence Among Teens Who Are Pregnant or Parenting","Inclusion Criteria:\n\nPregnant or parenting youth (Pilot RCT participants)\n\n* Aged 16-21 years.\n* Currently pregnant, partner of a pregnant person, or parenting a child (i.e., have contact with child at least once per week).\n* Able to speak and read English.\n* Willing and able to provide written informed consent.\n* Willing and able to provide adequate contact\u002Flocator information.\n\nFacilitators (IDI participants)\n\n* Aged 18 years or older.\n* Trained and served as a facilitator of the virtual SDYP intervention.\n* Able to speak and read English.\n* Able and willing to provide verbal informed consent.\n\nExclusion Criteria (Pilot RCT participants):\n\n* Has any other condition that, in the opinion of the PI or their designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.\n* Currently participating or will be participating in a violence prevention education program in the next 3 months.\n* Previously participated in the Empowering Young Parents study.","21 Years",{"count":289,"type":23},80,[26],"This project will study virtual delivery of Safe Dates for Young Parents (SDYP), a 10-session, group-based intimate partner violence (IPV) prevention program tailored for adolescents and young adults who are pregnant or parenting. This program has the potential to improve the health and well-being of young parents and their children, and virtual delivery may improve participants' ability to attend. The main questions it aims to answer are: (1) Is it feasible and acceptable to implement SDYP in a virtual setting? (2) Are SDYP participants less likely to experience IPV than participants in an alternate health education program? Participants will be invited to a series of virtual program sessions for either SDYP or a health education program focused on physical activity and nutrition and will be asked to complete surveys before the programs begin and up to 6 months later.",[293,294],"Gender-based Violence","Intimate Partner Violence",[296,297],"Young Adult Parents","Adolescent Pregnancy","2025-12-09",{"date":300,"type":43},"2025-12-15",{"date":302,"type":43},"2025-11-11",{"date":304,"type":23},"2026-07-31",{"name":49,"class":50},{"id":307,"slug":308,"hasResults":11,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":312,"eligibilityCriteria":313,"healthyVolunteers":17,"sex":18,"minAge":314,"maxAge":287,"enrollmentInfo":315,"targetDuration":4,"studyType":24,"phases":317,"briefSummary":318,"conditions":319,"keywords":320,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":323,"lastUpdatePostDateStruct":324,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":331},"100560365","empowering-young-parents-building-healthy-relationships-study-100560365","NCT06576193","Empowering Young Parents: Building Healthy Relationships Study","Empowering Young Parents: Building Health Relationships Study Evaluation of the Safe Dates for Young Parents Intervention","EYP","Inclusion Criteria:\n\nAdolescent and Young Adult (AYA) \\[EYP study participants\\]\n\n* Aged 14-21 years (inclusive) at Screening.\n* Assigned female sex at birth.\n* Currently pregnant or parenting their child who lives with them at least part-time.\n* Able to speak and read English or Spanish.\n* Able and willing to provide verbal informed consent for enrollment in the EYP study.\n* Able and willing to provide adequate contact\u002Flocator information.\n* Able and willing to complete protocol requirements, including completion of three study interviews over one year.\n\nStudy Facilitators (process evaluation participants)\n\n* Aged 18 years or older.\n* Trained and served as a facilitator of the SDYP intervention.\n* Able to speak and read English.\n* Able and willing to provide verbal informed consent.\n\nExclusion Criteria:\n\n* Per participant report at Screening or Enrollment, intends to travel away from their geographic area of residence for a time period that would interfere with study participation, including with intervention participation should the participant be randomized to the SDYP intervention.\n* Has any other condition that, in the opinion of the Principal Investigator (PI) or their designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives.","14 Years",{"count":316,"type":23},600,[26],"The goal of this trial is to learn how the Safe Dates for Young Parents (SDYP) intervention affects the sexual and reproductive health behaviors, and quality of, and attitudes surrounding intimate partner relationships in adolescents and young adults (AYA) assigned female sex at birth who are pregnant or parenting.\n\nThe main questions it aims to answer are:\n\n* Will the SDYP intervention have any effect on the sexual and reproductive health behaviors during the study period?\n* Will the SDYP intervention have any effect on the prevention or reduction of intimate partner violence (IPV)?\n* Will the SDYP intervention have any effect on the attitudes and beliefs about healthy relationships?\n\nResearchers will compare the behaviors, attitudes, and beliefs about sexual and reproductive health and relationships of participants assigned to the SDYP intervention group to participants assigned to the control (non-SDYP intervention) group to see if there is any difference or changes in those behaviors, attitudes, and beliefs before-and-after or without the SDYP intervention.\n\nParticipants in the SDYP intervention will attend ten (10) 50-minute group sessions that will involve interactive discussions, thinking through life-like scenarios, games, role-plays, brainstorming, and a poster contest and theatrical play.",[293,294],[296,297,321,322],"Adolescent Parents","Healthy Relationships","2025-10-28",{"date":325,"type":43},"2025-10-30",{"date":327,"type":43},"2024-10-16",{"date":329,"type":23},"2028-08",{"name":49,"class":50},12,{"id":333,"slug":334,"hasResults":11,"nctId":335,"briefTitle":336,"officialTitle":336,"acronym":337,"eligibilityCriteria":338,"healthyVolunteers":11,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":339,"targetDuration":4,"studyType":121,"phases":4,"briefSummary":340,"conditions":341,"keywords":343,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":353,"locationsCount":354},"100545744","recruitment-and-engagement-in-care-to-impact-practice-enhancement-recipe-for-sickle-cell-disease-100545744","NCT06385886","Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease","RECIPE","Inclusion Criteria:\n\n* Persons must be \\>\u002F= 18 years of age\n* Persons must have confirmed SCD\n* Persons not seen by a SCD specialist \\> 1 year +\u002F- 3 months\n* Literacy in English will be required of the consenting patient or parent\u002Fguardian\n\nExclusion Criteria:\n\n* Persons \\\u003C 18 years of age\n* Persons that are unable to provide informed consent and do not have a designated care-giver that can consent on his\u002Fher behalf\n* Persons with sickle cell trait (as per hemoglobin electrophoresis)\n* Persons seen by a SCD specialist \\\u003C 1 year +\u002F1 3 months",{"count":148,"type":23},"The goal of this observational study is to help us understand more about the best ways to help individuals living with Sickle Cell Disease (SCD) get the best care. The main question it aims to answer is: How to find individuals unaffiliated from SCD specialist care use three distinct pathways? Once unaffiliated individuals are found using the pathways, Investigators will employ linkage coordinators (trained staff) to engage these patients in care. Participants will be asked to fill out an assessment survey which will cover areas such as previous and current treatment, clinic and hospital experience, pain, and quality of life. Participants will also be given the option of participation in a 1-hour long interview how they feel about treatment for sickle cell disease including clinic experience, pain, and quality of life?",[342],"Sickle Cell Disease",[344,345,346],"Sickle Cell Disease Care","Unaffiliated patients","Linkage Coordinator","2025-06-19",{"date":349,"type":43},"2025-06-22",{"date":351,"type":43},"2023-06-08",{"date":278,"type":23},{"name":49,"class":50},9,{"id":356,"slug":357,"hasResults":11,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":362,"targetDuration":4,"studyType":24,"phases":364,"briefSummary":365,"conditions":366,"keywords":368,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":381,"locationsCount":87},"100587382","ensand-20-evaluation-in-nigeria-100587382","NCT06927661","ENSAND 2.0 Evaluation in Nigeria","Evaluation of the Global Alliance for Improved Nutrition (GAIN) the Enhancing Access to Safe and Nutritious Diets (ENSAND) 2.0 Project in Nigeria","Inclusion Criteria:\n\n* Farmer household or neighbor household recruited by ENSAND farmer\n* Located within an intervention LGA\n* Farmer must be member who is participating in the ENSAND project\n* Adult who is ≥ 18 years old\n* Able to speak English or Hausa\n* Provide informed consent to participate in the study",{"count":363,"type":23},1568,[26],"The Enhancing Access to Safe and Nutritious Diets 2.0 (ENSAND) (2024-2026) project is designed to address the low per capita consumption of vegetables and variety of vegetable consumption in northern Nigeria by working with smallholder farmers to increase production and promoting healthier diets through greater vegetable consumption among farmers and their neighbors. The objective of this evaluation is to assess the effectiveness of GAIN's ENSAND program for increasing the quantity and variety of vegetables consumed by smallholder farmer households participating in the program and neighbor households paired with the farmers. This evaluation will use a quasi-experimental design to assess the impact of GAIN's ENSAND programs on the quantity and diversity of vegetables consumed by smallholder farmers and their neighbors. The evaluation will be guided by the RE-AIM (reach, effectiveness, adoption, implementation, maintenance) framework. RE-AIM is a framework that is useful for evaluating the program impact of multifaceted and multilevel interventions.",[367],"Quantity and Variety of Vegetables Consumed",[369,370,371,372,373],"diet","vegetables","Nigeria","demand generation intervention","agricultural production intervention","2025-05-30",{"date":376,"type":43},"2025-06-04",{"date":378,"type":43},"2025-05-19",{"date":380,"type":23},"2026-12-31",{"name":49,"class":50},{"id":383,"slug":384,"hasResults":11,"nctId":385,"briefTitle":386,"officialTitle":387,"acronym":4,"eligibilityCriteria":388,"healthyVolunteers":17,"sex":59,"minAge":60,"maxAge":4,"enrollmentInfo":389,"targetDuration":4,"studyType":24,"phases":390,"briefSummary":391,"conditions":392,"keywords":393,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":374,"lastUpdatePostDateStruct":395,"startDateStruct":396,"completionDateStruct":398,"leadSponsor":400,"locationsCount":87},"100587383","deliver-evaluation-in-nigeria-100587383","NCT06927674","DELIVER Evaluation in Nigeria","Evaluation of the Global Alliance for Improved Nutrition (GAIN) DEcent LIVelihoods for Small-scale Producers Delivered Through Economic & Resilient Food Systems (DELIVER) Project in Nigeria","Inclusion Criteria:\n\n* Farmer household member or neighbor household recruited by DELIVER farmer\n* Located within the intervention LGA\n* Farmer must be a member who is participating in the DELIVER project\n* Adult who is ≥ 18 years old\n* Able to speak English or Hausa\n* Provide informed consent to participate in the study",{"count":363,"type":23},[26],"The DEcent LIVelihoods for small-scale producers delivered through Economic \\& Resilient food systems in Nigeria (DELIVER) (2024-2027) project is designed to address the low per capita consumption of vegetables and variety of vegetable consumption in northern Nigeria by working with smallholder farmers to increase production and promoting healthier diets through greater vegetable consumption among farmers and their neighbors. The objective of this evaluation is to assess the effectiveness of GAIN's DELIVER program for increasing the quantity and variety of vegetables consumed by smallholder farmer households participating in the program and by neighbor households. This evaluation will use a quasi-experimental design to assess the impact of GAIN's DELIVER programs on the quantity and diversity of vegetables consumed by smallholder farmers and non-farming neighbor households. The evaluation will be guided by the RE-AIM (reach, effectiveness, adoption, implementation, maintenance) framework. RE-AIM is a framework that is useful for evaluating the program impact of multifaceted and multilevel interventions.",[367],[369,370,394,371,373,372],"market intervention",{"date":376,"type":43},{"date":397,"type":43},"2025-05-12",{"date":399,"type":23},"2027-05-31",{"name":49,"class":50},""]