[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Recep Tayyip Erdogan University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":321},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,51,83,112,137,158,182,201,223,245,259,283],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":32,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100634695","kangaroo-care-breastfeeding-success-and-maternal-role-100634695",false,"NCT07543029","Kangaroo Care: Breastfeeding Success and Maternal Role","The Effect of Kangaroo Mother Care Applied in the Early Postpartum Period to Primiparous Mothers on Breastfeeding Success and Perception of the Maternal Role","Inclusion Criteria:\n\n* For mothers:\n\n  * It must be the mother's first birth,\n  * Birth must have been vaginal,\n  * The mother must be healthy,\n  * The mother must voluntarily participate in the study,\n  * The mother must not have any communication-impairing conditions (language, cognitive problems, etc.),\n\nFor babies:\n\n* Birth weight must be between 2500-4000 grams;\n* The newborn must be healthy,\n* Exclusively breastfed,\n* The newborn must be at term gestation (38-42 weeks),\n* The newborn's Apgar score at 1 and 5 minutes must be above 7,\n* The newborn must not have any health problems that could affect breastfeeding (cleft palate, cleft lip, esophageal atresia, etc.).\n\nExclusion Criteria:\n\n\\-",true,"FEMALE","18 Years","49 Years",{"count":21,"type":22},112,"ESTIMATED","INTERVENTIONAL",[25],"NA","Purpose: This is a randomized controlled trial designed to investigate the effects of Kangaroo Mother Care (KMC) applied in the early postpartum period to primiparous mothers on breastfeeding success and the perception of the maternal role.\n\nMethodology and Sample:\n\nSetting and Period: The study will be conducted at the Bucak State Hospital Delivery Unit between June 2025 and June 2026.\n\nSample Size: Based on G\\*Power analysis (alpha=0.05, power=80%, effect size d=0.566), a total of 112 mothers (56 intervention, 56 control) will be included, accounting for a 10% potential attrition rate. Participants will be assigned to groups using the sealed envelope method and randomization via www.random.org.\n\nIntervention:\n\nExperimental Group: Following routine care, the newborn will be placed in a \"chest-to-chest\" position on the mother's bare chest for Kangaroo Care. Intermittent KMC will be maintained for 24 hours, during which breastfeeding attempts will be supported.\n\nControl Group: Mothers and newborns will receive only the hospital's routine care (standard skin-to-skin contact and breastfeeding support).\n\nData Collection Tools:\n\nPersonal Information Form, Semantic Differential Scale-Myself as a Mother (to measure maternal role perception), LATCH Breastfeeding Assessment Tool (to evaluate breastfeeding success).",[28,29,30,31],"Breastfeeding","Maternal Role","Postpartum Care","Kangaroo Care",[33,34,35,36,37],"Primiparity","newborn","breastfeeding","maternal role","kangaroo care","RECRUITING","2026-06-11",{"date":41,"type":42},"2026-06-15","ACTUAL",{"date":44,"type":42},"2025-06-01",{"date":46,"type":22},"2026-12-30",{"name":48,"class":49},"Recep Tayyip Erdogan University","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":57,"eligibilityCriteria":58,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":50},"100608186","the-effect-of-different-flap-closure-techniques-on-postoperative-morbidity-in-impacted-third-molar-surgery-100608186","NCT07198282","The Effect of Different Flap Closure Techniques on Postoperative Morbidity in Impacted Third Molar Surgery","The Effect of Different Flap Closure Techniques on Postoperative Morbidity: A Randomized Controlled Trial for Impacted Third Molar Surgery","GMC02","Inclusion Criteria:\n\n* Patients aged 18-40 years.\n* Patients with no systemic diseases (ASA I).\n* Patients with impacted mandibular third molars indicated for extraction, with bone and\u002For mucosal retention, in similar positions (Pell \\& Gregory Class 2, Position B; Winter classification vertical or mesioangular).\n\nExclusion Criteria:\n\n* Patients classified as ASA II, III, or IV.\n* Known allergy to anesthetic solutions.\n* Allergy to acrylate.\n* Pregnant or breastfeeding women.\n* Individuals with tobacco use ≥10 cigarettes\u002Fday.\n* Alcohol users.\n* Patients using antiplatelet agents.\n* Patients using anticoagulants.\n* Patients with coagulation disorders.\n* Patients with immunosuppressive diseases or receiving immunosuppressive therapy.\n\nPatients with acute pain or local infection at the surgical site.","ALL","40 Years",{"count":62,"type":22},148,[25],"1\\. ABSTRACT This study is a randomized controlled trial comparing the clinical efficacy and safety of four different flap closure techniques in reducing postoperative morbidity (pain, swelling, trismus, wound healing) and improving patient quality of life (GOHAI) following impacted mandibular third molar extraction. The methods include conventional suturing, sutureless technique, surgical drain, and cyanoacrylate tissue adhesive, which are commonly used in oral surgery practice. The study aims to scientifically evaluate the effects of each method on patients and to determine the most appropriate clinical approach.",[66,67,68],"Impacted Mandibular Third Molar","Postoperative Morbidity","Oral Surgery",[70,71,72,73,74],"Impacted third molar","Flap closure techniques","Cyanoacrylate","Sutureless technique","Surgical drain","2026-06-08",{"date":77,"type":42},"2026-06-09",{"date":79,"type":42},"2026-05-08",{"date":81,"type":22},"2026-08-30",{"name":48,"class":49},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":59,"minAge":4,"maxAge":4,"enrollmentInfo":90,"targetDuration":4,"studyType":23,"phases":92,"briefSummary":93,"conditions":94,"keywords":96,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":50},"100598873","swaddling-and-facilitated-tucking-during-nasal-cpap-application-100598873","NCT07077148","Swaddling and Facilitated Tucking During Nasal CPAP Application","Effects of Swaddling and Facilitated Tucking on Newborn Pain, Stress and Comfort Levels During Nasal CPAP Application","Inclusion Criteria:\n\n* Those receiving nasal CPAP support,\n* Newborns between 34 0\u002F7 weeks and 36 6\u002F7 weeks of gestation,\n* Those without congenital anomalies,\n* Those without a health problem that prevents positioning,\n* Those without mental or neurological problems.\n\nExclusion Criteria:\n\n* Those with pneumothorax,\n* Newborns who received opioids or sedatives 4 hours before the procedure,\n* Intubated newborns\n* Newborns with a gestational age greater than 37 weeks",{"count":91,"type":22},114,[25],"This study was planned to determine the effects of fetal position and swaddling during nasal CPAP application on pain, stress level, comfort and physiological parameters of the newborn. The research is a randomized controlled trial. The study will be conducted in the neonatal intensive care unit of a Training and Research Hospital between May 2026 and December 2026. Newborns who meet the study criteria from the specified universe will constitute the sample of the study. \"Newborn Identification Information Form\", \"ALPS Neo Neonatal Pain and Stress Assessment Scale\", \"Premature Baby Comfort Scale\" and \"Physiological Parameter Follow-up Form\" will be used to collect data. will be used.",[95],"Respiratory Disease of A Newborn",[97,98,99,100,101,102],"facilitated tucking","Nasal cpap","swaddling","pain","comfort","stress","NOT_YET_RECRUITING","2026-04-13",{"date":106,"type":42},"2026-04-16",{"date":108,"type":22},"2026-05-01",{"date":110,"type":22},"2027-04-30",{"name":48,"class":49},{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":119,"enrollmentInfo":120,"targetDuration":4,"studyType":23,"phases":122,"briefSummary":123,"conditions":124,"keywords":126,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":136,"locationsCount":4},"100624546","effects-of-body-awareness-therapy-on-physical-and-psychosocial-outcomes-in-adults-with-asthma-100624546","NCT07411040","Effects of Body Awareness Therapy on Physical and Psychosocial Outcomes in Adults With Asthma","Effect of Body Awareness Therapy on Physical and Psychosocial Outcomes in Adults With Asthma: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged between 18 and 65 years.\n* Clinically diagnosed asthma confirmed by a physician.\n* Stable asthma condition (no acute exacerbation in the last 4 weeks).\n* Receiving regular medical treatment for asthma.\n* Able to understand and follow instructions for the intervention.\n* Willing to participate and provide written informed consent.\n\nExclusion Criteria:\n\n* Diagnosis of chronic respiratory diseases other than asthma (e.g., COPD, bronchiectasis).\n* Acute asthma exacerbation within the last 4 weeks.\n* Severe cardiovascular, neurological, or musculoskeletal conditions that may limit participation in physical activity.\n* Current participation in another structured exercise or rehabilitation program.\n* History of major psychiatric disorders that may interfere with participation (e.g., psychotic disorders).\n* Pregnancy.\n* Cognitive impairment affecting the ability to follow instructions.","65 Years",{"count":121,"type":22},67,[25],"This study aims to investigate the effects of Body Awareness Therapy on physical and psychosocial outcomes in adults with asthma. Asthma is a chronic respiratory condition that can affect breathing, physical activity, and emotional well-being. In addition to medical treatment, non-pharmacological approaches that support body awareness and breathing may help individuals manage their symptoms more effectively.\n\nParticipants in this study will be randomly assigned to either a Body Awareness Therapy group or a control group receiving standard care. The Body Awareness Therapy program includes guided exercises focusing on posture, breathing, movement, and awareness of bodily sensations. The program will be delivered over several weeks by a trained physiotherapist.\n\nThe main outcomes of the study include physical function, respiratory symptoms, quality of life, psychological well-being, and body awareness levels. The results of this study are expected to provide evidence on whether Body Awareness Therapy can be an effective supportive approach in asthma management and rehabilitation.",[125],"Asthma",[127,128,129],"asthma","body awareness","body awareness therapy","2026-02-06",{"date":132,"type":42},"2026-02-13",{"date":134,"type":22},"2026-02-01",{"date":108,"type":22},{"name":48,"class":49},{"id":138,"slug":139,"hasResults":11,"nctId":140,"briefTitle":141,"officialTitle":141,"acronym":4,"eligibilityCriteria":142,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":143,"enrollmentInfo":144,"targetDuration":4,"studyType":23,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":154,"startDateStruct":155,"completionDateStruct":156,"leadSponsor":157,"locationsCount":4},"100624548","effects-of-clinical-pilates-on-physical-and-psychosocial-outcomes-in-individuals-with-interstitial-lung-disease-100624548","NCT07411066","Effects of Clinical Pilates on Physical and Psychosocial Outcomes in Individuals With Interstitial Lung Disease","Inclusion Criteria:\n\n* Adults aged 18 to 75 years.\n* Clinically confirmed diagnosis of interstitial lung disease (ILD) by a physician.\n* Clinically stable condition (no acute exacerbation or hospitalization related to ILD within the last 4 weeks).\n* On stable medical treatment and routine follow-up.\n* Able to walk and participate in low-to-moderate intensity exercise as determined by the clinician\u002Fphysiotherapist.\n* Able to understand study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Coexisting chronic respiratory disease that may confound outcomes (e.g., COPD, uncontrolled asthma, bronchiectasis).\n* Acute exacerbation of ILD or hospitalization within the last 4 weeks.\n* Unstable cardiovascular disease or other medical conditions making exercise unsafe (e.g., unstable angina, recent myocardial infarction).\n* Severe neurological, musculoskeletal, or balance disorders limiting safe participation in exercise.\n* Pulmonary hypertension or oxygen dependency requiring unstable\u002Fhigh-flow support if judged unsafe for exercise participation by the treating clinician.\n* Current participation in another structured exercise \u002F pulmonary rehabilitation program during the study period.\n* Major psychiatric disorder or cognitive impairment interfering with participation or adherence.\n* Pregnancy.","75 Years",{"count":145,"type":22},58,[25],"This study aims to investigate the effects of Clinical Pilates on physical and psychosocial outcomes in individuals with interstitial lung disease (ILD). Interstitial lung disease is a group of chronic conditions that affect lung tissue and can lead to breathing difficulties, reduced physical capacity, fatigue, and decreased quality of life.\n\nIn addition to medical treatment, exercise-based rehabilitation approaches may help individuals with ILD improve their physical function and overall well-being. Clinical Pilates is a structured exercise method that focuses on breathing control, posture, core stability, flexibility, and body awareness.\n\nParticipants in this study will be randomly assigned to either a Clinical Pilates group or a control group receiving standard care. The Clinical Pilates program will be delivered by a trained physiotherapist over several weeks through supervised sessions.\n\nThe main outcomes of this study include physical function, respiratory symptoms, quality of life, and psychological well-being. The results of this study are expected to provide evidence on whether Clinical Pilates can be an effective and safe supportive approach for pulmonary rehabilitation in individuals with interstitial lung disease.",[149],"Interstitial Lung Disease (ILD)",[151,152,153],"interstitial lung disease","clinical pilates","pilates",{"date":132,"type":42},{"date":134,"type":22},{"date":108,"type":22},{"name":48,"class":49},{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":166,"enrollmentInfo":167,"targetDuration":4,"studyType":23,"phases":169,"briefSummary":170,"conditions":171,"keywords":173,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":177,"startDateStruct":178,"completionDateStruct":179,"leadSponsor":181,"locationsCount":50},"100624545","body-awareness-based-rehabilitation-on-physical-psychosocial-status-in-patellofemoral-pain-syndrome-100624545","NCT07411027","Body Awareness-Based Rehabilitation on Physical Psychosocial Status in Patellofemoral Pain Syndrome","The Effects of Body Awareness-Based Sensorimotor Rehabilitation on Physical Psychosocial Status in Patellofemoral Pain Syndrome","BASPR-PFP","Inclusion Criteria:\n\n* Adults aged 18-45 years.\n* Clinical diagnosis of patellofemoral pain syndrome with anterior or retropatellar knee pain.\n* Knee pain lasting for at least 3 months.\n* Pain intensity of at least moderate level during functional activities such as stair climbing, squatting, or prolonged sitting.\n* Ability to understand and follow instructions and provide informed consent.\n* Willingness to participate in the rehabilitation program.\n\nExclusion Criteria:\n\n* History of knee surgery within the past 12 months.\n* Presence of other knee pathologies (e.g., ligament injury, meniscal tear, osteoarthritis).\n* Diagnosis of inflammatory or rheumatological diseases.\n* Neurological disorders affecting balance or movement.\n* Current pregnancy.\n* Participation in another structured physiotherapy or rehabilitation program within the past 3 months.\n* Any condition that may prevent safe participation in exercise.","45 Years",{"count":168,"type":22},60,[25],"Patellofemoral pain syndrome is a common knee condition that causes pain around or behind the kneecap, especially during activities such as walking, climbing stairs, squatting, or prolonged sitting. This condition can affect daily activities, movement quality, and psychological well-being.\n\nThe purpose of this study is to investigate the effects of a body awareness-based sensorimotor rehabilitation program on pain behavior, movement quality, and psychosocial outcomes in individuals with patellofemoral pain syndrome.\n\nParticipants will be randomly assigned to either an intervention group receiving body awareness-based sensorimotor rehabilitation or a control group receiving conventional physiotherapy exercises. The rehabilitation program will focus on improving body awareness, posture, balance, and controlled movement patterns.\n\nOutcomes will be assessed before and after the intervention period. The main outcomes include changes in pain-related behaviors, movement quality, and psychosocial status.\n\nThe results of this study are expected to provide evidence on whether body awareness-based sensorimotor rehabilitation can be an effective approach for managing patellofemoral pain and improving both physical and psychological aspects of function.",[172],"Patellofemoral Pain Syndrome",[174,175,176],"Patellofemoral pain syndrome","Body awareness","Physiotherapy",{"date":132,"type":42},{"date":134,"type":22},{"date":180,"type":22},"2026-06-01",{"name":48,"class":49},{"id":183,"slug":184,"hasResults":11,"nctId":185,"briefTitle":186,"officialTitle":186,"acronym":4,"eligibilityCriteria":187,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":119,"enrollmentInfo":188,"targetDuration":4,"studyType":23,"phases":190,"briefSummary":191,"conditions":192,"keywords":194,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":197,"startDateStruct":198,"completionDateStruct":199,"leadSponsor":200,"locationsCount":4},"100624547","the-effects-of-ems-combined-body-awareness-exercises-on-non-specific-low-back-pain-100624547","NCT07411053","The Effects of EMS-Combined Body Awareness Exercises on Non-Specific Low Back Pain","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Diagnosed with non-specific low back pain for at least 3 months\n* Pain intensity of ≥4 on the Numeric Rating Scale (NRS)\n* Ability to understand and follow exercise instructions\n* Willingness to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n* Specific causes of low back pain (e.g., disc herniation with neurological deficit, spinal stenosis, spondylolisthesis, fracture, infection, tumor)\n* History of spinal surgery within the last 12 months\n* Known neurological disorders affecting movement or sensation\n* Diagnosed rheumatological or inflammatory diseases (e.g., ankylosing spondylitis, rheumatoid arthritis)\n* Pregnancy\n* Presence of cardiac pacemaker or implanted electronic devices (contraindication for EMS)\n* Severe osteoporosis or other conditions contraindicating exercise\n* Current participation in another structured physiotherapy or rehabilitation program\n* Cognitive impairment or psychiatric conditions limiting cooperation with the protocol",{"count":189,"type":22},72,[25],"Low back pain is one of the most prevalent musculoskeletal conditions worldwide and is a leading cause of disability and reduced quality of life. Non-specific low back pain (NSLBP), which has no identifiable underlying pathology, accounts for the majority of low back pain cases and often requires a multidisciplinary rehabilitation approach.\n\nBody awareness-based exercises aim to improve postural control, movement quality, and the individual's perception of bodily sensations, and have been shown to be beneficial in chronic pain management. Electrical muscle stimulation (EMS) is a non-invasive modality that enhances neuromuscular activation and may support functional recovery when combined with exercise interventions.\n\nThe purpose of this study is to investigate the effects of EMS-combined body awareness exercises on pain intensity, functional disability, and body awareness in individuals with non-specific low back pain. Participants will be randomly assigned to either an intervention group receiving EMS-assisted body awareness training or a control group receiving standard body awareness exercises. Outcome measures will be assessed before and after the intervention period.\n\nThis study aims to provide evidence on whether the addition of EMS to body awareness-based rehabilitation leads to superior clinical outcomes compared to body awareness exercises alone in individuals with non-specific low back pain.",[193],"Low Back Pain",[193,195,196],"Electrical Muscle Stimulation","Body Awareness",{"date":132,"type":42},{"date":134,"type":22},{"date":180,"type":22},{"name":48,"class":49},{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":207,"eligibilityCriteria":208,"healthyVolunteers":16,"sex":59,"minAge":18,"maxAge":4,"enrollmentInfo":209,"targetDuration":4,"studyType":23,"phases":211,"briefSummary":212,"conditions":213,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":215,"lastUpdatePostDateStruct":216,"startDateStruct":218,"completionDateStruct":220,"leadSponsor":222,"locationsCount":50},"100617357","the-effect-of-body-awareness-therapy-on-pain-function-and-psychosocial-parameters-in-temporomandibular-joint-disorders-100617357","NCT07317570","The Effect of Body Awareness Therapy on Pain, Function and Psychosocial Parameters in Temporomandibular Joint Disorders","A Randomized, Single-Blind Controlled Trial Investigating the Effect of Body Awareness Therapy on Pain, Functional Outcomes, and Psychosocial Parameters in Adults With Temporomandibular Joint Disorders","BAT-TMJ","Inclusion Criteria:\n\nAdults aged 18-65 years. Diagnosed with Temporomandibular Joint Disorders (TMD) according to the Diagnostic Criteria for Temporomandibular Disorders (DC\u002FTMD).\n\nExperiencing orofacial pain or jaw functional limitation for at least the past 3 months.\n\nAbility to understand and follow verbal instructions required for Body Awareness Therapy sessions.\n\nWillingness to participate in the study and to attend all assessment and intervention sessions.\n\nProviding written informed consent.\n\nExclusion Criteria:\n\nHistory of jaw trauma, fracture, or surgery within the past 6 months. Presence of systemic rheumatologic or inflammatory disorders (e.g., rheumatoid arthritis, ankylosing spondylitis) that may affect TMJ function.\n\nNeurological or psychiatric conditions that could interfere with participation or outcome assessments (e.g., major psychiatric disorder, cognitive impairment).\n\nSevere dental or orthodontic conditions requiring immediate treatment (e.g., acute infection, ongoing orthodontic procedures).\n\nUse of occlusal splints, bite guards, or other TMJ-related interventions initiated within the past 3 months.\n\nParticipation in any other physiotherapy or exercise program targeting the jaw, cervical spine, or posture during the study period.\n\nPregnancy, due to potential changes in joint laxity and pain perception. Current use of medications affecting neuromuscular or pain responses, such as muscle relaxants, corticosteroids, or neuropathic pain medications (unless dose has been stable for 3 months).\n\nAny contraindication to performing light-to-moderate physical activity or awareness-based exercises.\n\nInability to attend scheduled therapy sessions or complete study assessments.",{"count":210,"type":22},52,[25],"This randomized, single-blind controlled trial aims to investigate the effectiveness of Body Awareness Therapy (BAT) on pain, functional limitations, and psychosocial outcomes in individuals with temporomandibular joint disorders (TMD). TMD is characterized by orofacial pain, impaired jaw function, and increased psychosocial burden, yet current physiotherapy approaches may not fully address the biopsychosocial mechanisms underlying these symptoms. BAT is a structured mind-body physiotherapy intervention designed to improve postural awareness, interoceptive sensitivity, breathing regulation, and movement control.\n\nIn this study, participants will be randomly assigned to either BAT or a standard physiotherapy control intervention for a defined treatment period. Primary outcomes will include pain intensity and jaw functional limitations, while secondary outcomes will assess body awareness, anxiety, stress, and quality of life. Evaluations will be conducted at baseline and post-intervention. The findings of this trial may provide evidence for integrating biopsychosocial and awareness-based physiotherapy into TMD rehabilitation.",[214],"Temporomandibular Joint Disorders","2026-01-31",{"date":217,"type":42},"2026-02-03",{"date":219,"type":42},"2025-12-20",{"date":221,"type":22},"2026-05-20",{"name":48,"class":49},{"id":224,"slug":225,"hasResults":11,"nctId":226,"briefTitle":227,"officialTitle":228,"acronym":4,"eligibilityCriteria":229,"healthyVolunteers":16,"sex":59,"minAge":18,"maxAge":4,"enrollmentInfo":230,"targetDuration":232,"studyType":233,"phases":4,"briefSummary":234,"conditions":235,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":50},"100619317","evaluation-of-the-effect-of-flowable-composites-on-postoperative-sensitivity-in-class-i-restorations-100619317","NCT07343050","Evaluation of the Effect of Flowable Composites on Postoperative Sensitivity in Class I Restorations.","Evaluation of Dental Restorations","Inclusion Criteria:\n\n* good general health\n* no heart disease\n* no diabetes\n* no systemic diseases such as hypertension\n\nExclusion Criteria:\n\n* Patients with advanced periodontitis and associated postoperative sensitivity,\n* Pregnant and breastfeeding women,\n* Patients undergoing orthodontic treatment,\n* Patients using appliances,\n* Patients with direct pulp capping",{"count":231,"type":22},120,"24 Months","OBSERVATIONAL","The aim of this study is to evaluate the effect of flowable conventional and bulk-fill composites on postoperative sensitivity in class I cavities over long-term follow-up. The hypothesis to be tested in this study is that the type of composite material will not affect clinical success.",[236],"Dentin Caries","2026-01-06",{"date":239,"type":42},"2026-01-15",{"date":241,"type":42},"2025-05-16",{"date":243,"type":22},"2027-08-01",{"name":48,"class":49},{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":4,"eligibilityCriteria":251,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":4,"enrollmentInfo":252,"targetDuration":232,"studyType":233,"phases":4,"briefSummary":253,"conditions":254,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":255,"startDateStruct":256,"completionDateStruct":257,"leadSponsor":258,"locationsCount":50},"100619318","evaluation-of-the-clinical-performance-of-different-composite-materials-in-class-iii-and-iv-restorations-100619318","NCT07343063","Evaluation of the Clinical Performance of Different Composite Materials in Class III and IV Restorations.","Evaluation of Anterior Restorations","Inclusion Criteria:\n\n* Good general health\n* No heart disease,\n* No diabetes\n* No systemic diseases such as hypertension\n\nExclusion Criteria:\n\n* Individuals with advanced periodontitis and associated postoperative sensitivity\n* Pregnant and breastfeeding women\n* Individuals undergoing orthodontic treatment and using appliances\n* Individuals with direct pulp capping\n* Individuals with bruxism",{"count":231,"type":22},"In this study, a universal adhesive was used with different adhesive techniques (self-etch and total-etch modes) and evaluated for 18 months in three different types of composite material class III and class IV restorations according to the FDI criteria. The hypotheses tested in this study are: (1) clinical success will not differ between different composite materials and (2) clinical outcomes will not differ between different application modes of the universal adhesive.",[236],{"date":239,"type":42},{"date":241,"type":42},{"date":243,"type":22},{"name":48,"class":49},{"id":260,"slug":261,"hasResults":11,"nctId":262,"briefTitle":263,"officialTitle":264,"acronym":4,"eligibilityCriteria":265,"healthyVolunteers":16,"sex":59,"minAge":18,"maxAge":119,"enrollmentInfo":266,"targetDuration":4,"studyType":233,"phases":4,"briefSummary":267,"conditions":268,"keywords":271,"overallStatus":103,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":279,"completionDateStruct":281,"leadSponsor":282,"locationsCount":4},"100614527","evaluation-of-25ohd3-and-ll-37-levels-in-periimplant-sulcus-fluid-100614527","NCT07280754","Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid","Evaluation of 25(OH)D3 and LL-37 Levels in Peri-implant Sulcus Fluid in Peri-implant Diseases","Inclusion Criteria:\n\n* Being between the ages of 18-65,\n* Having dental implants and using implant-supported prostheses for at least one year,\n* Not having used systemic and\u002For topical antibiotics\u002Fanti-inflammatory drugs or mouthwashes in the last three months,\n* Not having received periodontal\u002Fperi-implant treatment in the last six months.\n\nExclusion Criteria:\n\n* Having a systemic disease or condition that affects peri-implant status,\n* Having a metabolic bone disease,\n* Bruxism,\n* Being pregnant or lactating,\n* Having received periodontal\u002Fperi-implant treatment within the last 6 months,\n* Smoking and alcohol use,\n* Taking vitamin D supplements.",{"count":189,"type":22},"Despite technological advances that have significantly improved dental implant osseointegration and survival rates, biological complications such as peri-implantitis and peri-implant mucositis are common around the implant. The active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), can be induced by the expression of leucine-lysine-37 (LL-37), a human antimicrobial peptide in the cathelicidin family. Studies have shown that 1,25(OH)2D3 and its precursor, 25(OH)D3, significantly reduce inflammation by suppressing the release of receptor activator nuclear factor kappa b ligand (RANKL), tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1, and IL-6, and by preventing alveolar bone loss. To date, many cytokines have been investigated in peri-implant sulcus fluid (PIOS). The lack of a direct study investigating vitamin D and LL-37 levels in PIOS constitutes the unique value of this project. This study aims to compare LL-37 and 25(OH)D3 levels in PIOS and examine their correlation with markers such as IL-6, IL-10, and MMP-8, as well as clinical parameters. Volunteers aged 18-65 who have received dental implants at the Recep Tayyip Erdoğan University Faculty of Dentistry and have been using their implant-supported prosthesis for at least one year and who have been informed about this study will be included in the study. The groups will be formed as peri-implant health, peri-implant mucositis, and peri-implantitis. The implants of the patients included in the study will be evaluated for probed pocket depth (PPD), clinical attachment level (CAL), suppuration (S), modified gingival index (mGI), plaque index (mPI), bleeding index (mBI), keratinized gingival amount, and attached gingival amount. PIOS and serum samples will be obtained from patients, and their relationship to periodontal status and each other will be statistically evaluated.\n\nThis project may help discover new biomarkers that can be used in the early diagnosis of peri-implantar diseases. This study could contribute to earlier treatment, lower patient costs, and even the development of new treatment plans for these diseases.",[269,270],"Peri Implantitis","Peri Implant Mucositis",[272,273,274,275],"LL-37","peri-implanter sulcus fluid","peri-implantitis","vitamin D","2025-12-12",{"date":278,"type":42},"2025-12-19",{"date":280,"type":22},"2025-12-30",{"date":180,"type":22},{"name":48,"class":49},{"id":284,"slug":285,"hasResults":11,"nctId":286,"briefTitle":287,"officialTitle":288,"acronym":289,"eligibilityCriteria":290,"healthyVolunteers":11,"sex":59,"minAge":18,"maxAge":4,"enrollmentInfo":291,"targetDuration":4,"studyType":233,"phases":4,"briefSummary":293,"conditions":294,"keywords":300,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":312,"lastUpdatePostDateStruct":313,"startDateStruct":315,"completionDateStruct":317,"leadSponsor":319,"locationsCount":320},"100513064","pressure-recording-analytical-method-parameters-and-their-relationship-with-hypotension-in-hypertensive-patients-100513064","NCT05960604","Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients","Observational Study to Evaluate the Pressure Recording Analytical Method Parameters in Patients Susceptible to Post-induction Hypotension Due to Hypertension, Diabetes Mellitus, Cardiovascular Risk Factors, or Major Surgery","PRAM-in-HYPO","Inclusion Criteria:\n\n* Age at least 18 years\n* Undergoing major surgery under general anesthesia\n* Expected surgery time \\>2 h\n* Expected length of postoperative stay \\>2 d\n* Invasive blood pressure (radial or femoral) and Mostcare monitoring\n* Indication for a passive leg raising test: risk of hypovolemia (preoperative fasting, bowel preparation, loss of appetite, limited access to water) or expected major surgery, expected blood loss, cardiovascular comorbidity (hypertension, diabetes mellitus, coronary artery disease, peripheral artery disease, hyperlipidemia, morbidity, active smoking).\n* Recruitment after booking for surgery with sufficient time to read, understand and question study patient information prior to attending for surgery.\n* Ability and willingness to provide informed consent\n\nExclusion Criteria:\n\n* Refuse to consent to the study\n* Arterial wave form distortion\n* Cardiac arrhythmia\n* Inappropriate identification of the dicrotic notch for any reason\n* Planned intraoperative mean arterial blood pressure \\\u003C 65 mmHg\n* Hemodynamic instability defined as mean arterial blood pressure \\\u003C 65 mmHg\n* Preoperative requirement of inotrope\u002Fvasopressor infusion\n* Preoperatively receiving vasoactive drugs\n* Patients fitted with an intra-aortic balloon pump\n* Patients fitted with Extracorporeal Membrane Oxygenation\n* Critically ill patients requiring preoperative intensive care unit\n* Presence of intraabdominal hypertension\n* New York Heart Association Class 3-4 heart failure\n* Congestive heart failure with ejection fraction \\\u003C 35%\n* Glomerular filtration rate \\\u003C 30 ml\u002Fmin\u002F1.73 m2\n* Ongoing renal replacement therapy",{"count":292,"type":22},660,"Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management and improve patient outcomes. Parameters of the Pressure Recording Analytical Method (PRAM; Vygon, Padua, Italy) of the MostCare system, specifically cardiac cycle efficiency has been proposed as such variables. Yet, their value in anesthesia and especially in hypertensive patients is not studied. The goal of the PRAM-in-HYPO study is to prospectively evaluate the relationship between cardiac reserve and efficiency and cardiovascular risk factors in patients wo will undergo major surgical procedures using the state-of-the-art hemodynamic monitors. Also the investigators aim to build a predictive model to identify patients with decreased cardiac reserve due to hypertension and other cardiovascular risk factors, who are susceptible to post-induction hypotension. The investigators seek to include high-risk patients or patients presenting for major surgery, who are monitored with an advanced hemodynamic monitor to adequately evaluate the differences in cardiac reserve and cardiac efficiency.",[295,296,297,298,299],"Cardiovascular Diseases","Surgery","Hypotension","Hypotension on Induction","Hypotension During Surgery",[301,302,303,304,305,306,307,308,309,310,311],"Mostcare","Pressure Recording Analytical Method","Pulse contour analysis","Hemodynamic monitoring","Effective arterial elastance","Cardiac cycle efficiency","Cardiac power output","Myocardial contraction","Cardiac output","Stroke volume","Systemic vascular resistance","2025-04-08",{"date":314,"type":42},"2025-04-09",{"date":316,"type":42},"2024-02-19",{"date":318,"type":22},"2027-06",{"name":48,"class":49},5,""]