[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Royal National Orthopaedic Hospital NHS Trust\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":128},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,39,72,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100643259","clinical-examination-of-cavovarus-feet-100643259",false,"NCT07644078","Clinical Examination of Cavovarus Feet","Identification of Forefoot Morphotypes in Cavovarus Feet Without the Need for Specialised Software","Inclusion Criteria:\n\n* Adult patients aged ≥ 18 years\n* Clinical diagnosis of cavovarus foot deformity, AND confirmed Charcot-Marie-Tooth disease or other hereditary sensorimotor neuropathy\n* Already under the care of the Foot \\& Ankle Unit at RNOH.\n\nAdditionally, for PROSPECTIVE element:\n\n• Capacity to provide written informed consent\n\nAdditionally, for the RETROSPECTIVE element:\n\n* Previously assessed for cavovarus feet at RNOH\n* Forefoot morphotype previously identified using Disior Bonelogic software\n* Clinical examination findings documented in medical notes.\n\nExclusion Criteria:\n\n* Previous surgery to the hindfoot or midfoot\n* Age under 18 years\n\nFor the PROSPECTIVE element:\n\n• Unable to consent\n\nFor the RETROSPECTIVE element:\n\n* Participant has previously withdrawn consent for use of their data in line with NHS Opt-out\n* Insufficient clinical examination data recorded in medical notes.","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","1 Day","OBSERVATIONAL","Cavovarus feet are complex deformities in multiple planes. There is little consensus on the best way to address deformities. Furthermore there are various different phenotypes and we have previously described 4 distinct forefoot morphotypes that exist. It has been hypothesised that the various morphotypes could benefit from differing surgical strategies.\n\nHowever, identification of forefoot morphotypes has only been possible thus far using specialised semi-automated software and 3D animating software to manually identify morphotypes. It is therefore not straightforward to identify which patients may benefit from which surgery and this is not translatable to surgeons outside of a specialist centre.\n\nThe utility of this classification has been thus far limited to research. There is a burning need to explore ways in which identification of forefoot morphotypes can be translated to other centres using techniques such as basic imaging or clinical examination to identify patients with different morphotypes.\n\nAt Royal National Orthopaedic Hospital (RNOH) we have a large, complex cohort of patients with neuromuscular foot and ankle deformity and cavovarus feet. We also have access to advanced imaging techniques which we employ in routine care of our patients. We further have access to the software and previous research tools used to identify forefoot morphotypes.\n\nWe have for many years been examining cavovarus feet and documenting the various clinical findings. We also run teaching clinics combined with registrars where patients are routinely examined as part of routine care and pre-operative work up.\n\nTherefore we are ideally and uniquely placed to carry out this research which is an extension of our previous work. Our primary aim is to identify a reproducible method of distinguishing between the various forefoot morphotypes in cavovarus feet in patients with Charcot Marie Tooth disease (CMT). This will include investigating the utility of clinical examination and manual measurements (without specialised software) on weightbearing CT (WBCT). We will also aim to examine the reproducibility of any techniques such as clinical examination.",[25],"Cavus Foot","RECRUITING","2026-06-08",{"date":29,"type":30},"2026-06-12","ACTUAL",{"date":32,"type":30},"2026-05-28",{"date":34,"type":20},"2027-12-31",{"name":36,"class":37},"Royal National Orthopaedic Hospital NHS Trust","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":4},"100626687","dynamic-lycra-garments-for-hip-dysplasia-feasibility-study-100626687","NCT07438873","Dynamic Lycra Garments for Hip Dysplasia Feasibility Study","Dynamic Lycra Garments to Address Pain and Instability Associated With Hip Dysplasia: a Single Cohort Observational Pilot Study","HIPlycra","Inclusion Criteria:\n\n* 18 years of age or over\n* Clinical diagnosis of Develomental Dysplasia of the Hip (DDH)\n* Clinical diagnosis of hypermobility\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Clinical diagnosis of additional musculoskeletal pathology affecting hips or pelvis",{"count":48,"type":20},12,"INTERVENTIONAL",[51],"NA","Dynamic lycra garments are deployed in rehabilitation and exercise to support unstable areas of the body, enhance sensory feedback to improve movement patterns, reduce fatigue and pain and improve function.\n\n2 case studies have respectively highlighted the effective use of postural correction to reduce hip pain in an adult with acetabular dysplasia while lycra orthoses have reduced pain and improved stability in the hip. Larger scale studies assessing the effect of lycra garments across a clinical population of those presenting with combined hypermobility and hip dysplasia are needed to investigate the extent of generalisable effects.\n\nThe research question underpinning the project is as follows,\"Can the use of dynamic compression shorts during daily activities improve short term treatment outcomes in hip dysplasia patients?\".\n\nThe intention of this single cohort, observational pilot is primarily to establish the feasibility of studying the effect of the garments and assess the justification for further quantitative study, rather than the adjunctive effect of the shorts themselves.\n\nThe investigators are aiming to recruit 8-10 participants who will form a single cohort for observation, with the aim of gathering chiefly qualitative outcomes. This feasibility study is not intended to be blinded.",[54,55],"Hip Dysplasia","Hypermobility Syndrome",[57,58,59,60,61,62],"Hypermobility","Orthotic","Hip dysplasia","Physiotherapy","Lycra","Dynamic lycra garments","NOT_YET_RECRUITING","2026-02-23",{"date":66,"type":30},"2026-02-27",{"date":68,"type":20},"2026-03-03",{"date":70,"type":20},"2027-09-08",{"name":36,"class":37},{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":49,"phases":82,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":38},"100623140","virtual-reality-supported-exercise-for-chronic-musculoskeletal-shoulder-disorders-a-feasibility-study-100623140","NCT07392762","Virtual Reality-Supported Exercise for Chronic Musculoskeletal Shoulder Disorders: a Feasibility Study","Virtual Reality-Supported Exercise for Chronic Musculoskeletal Shoulder Disorders: a Feasibility Study (The V-RECS Study)","V-RECS","Inclusion Criteria:\n\n* Adult patients \\>18 years with diagnosed unilateral\u002F bilateral shoulder pain with\u002F without co-existing symptoms of instability and or stiffness (persisting \\> three months) generated from a Musculoskeletal origin\n* Patients who have been referred for conservative management\n* New or follow-up patients\n* Sufficient English to understand written materials\u002Fverbal instruction\u002For accompanied by family\u002Ffriends able to translate\n* Patients who provide informed, written consent to enter the study\n\nExclusion Criteria:\n\n* Unable to provide informed consent\n* On a waiting list for surgery and\u002For injections\n* Referred for post-operative physiotherapy\n* Shoulder pain not originating from an MSK aetiology (such as hemiplegia or peripheral nerve injury)\n* Active history of seizures\n* Other relevant medical conditions deemed inappropriate for patients to participate e.g. visual impairment, unstable psychiatric illnesses.\n* Shoulder pain associated with bone metastasis\n* Currently taking part in any other upper limb research study\n* Patients who do not adequately understand verbal explanations or written information given in English (or are not accompanied by an interpreter\u002Ffamily member).",{"count":81,"type":20},20,[51],"People with long-term (chronic) shoulder disorders caused by injuries, overuse or conditions (such as arthritis) often need physiotherapy. This usually includes exercise therapy to help reduce pain, rebuild strength and make every day activities easier. However, it can be hard to stick to an exercise programme. People may stop due to pain, fear of making the symptoms worse or simply loosing motivation.\n\nVirtual Reality (VR) is a technology that may help people say engaged with their exercise programmes by making exercises more enjoyable and interactive. When using a headset (similar to goggles), people can see and interact with a 3D virtual world. Their movement, especially their hands and arms, are shown as an 'avatar' (a virtual character) in this virtual world. Exercise can feel more like playing a game or engaging with tasks\u002Fchallenges, rather than performing repetitive movements. This shift might help reduce focus on pain and increase motivation. VR also provides real-time feedback, helping people track their progress and adjust their movements instantly. This might lead to more accurate and consistent exercise performance and better recovery outcomes.\n\nBefore we can test whether VR exercise programmes are effective for people with chronic shoulder disorders, we firstly need to understand whether it is practical and acceptable for patients to use. This 'feasibility' study will therefore involve 20 patients with chronic shoulder disorders referred for physiotherapy at the Royal National Orthopaedic Hospital (RNOH) in Stanmore, United Kingdom. Participants will take part in three VR exercise sessions at the RNOH over a three-week period. Levels of pain, quality of life and sleep quality etc. will be measured before and after three weeks. Interviews will also be held up to two weeks after the final session to explore people's experiences and thoughts towards the VR exercise programme. The results will help us decide if a larger study should go ahead.",[85,86,87],"Shoulder Pain","Chronic Shoulder Pain","Musculoskeletal Shoulder Pain",[89,90,91,87,86,92],"Virtual Reality","VR","Musculoskeletal Rehabilitation","Shoulder pain disorders","2026-01-29",{"date":95,"type":30},"2026-02-06",{"date":97,"type":20},"2026-01-16",{"date":99,"type":20},"2026-12",{"name":36,"class":37},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":108,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":49,"phases":111,"briefSummary":112,"conditions":113,"keywords":116,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":4},"100620768","ra-anatomy---vrvst-study-100620768","NCT07361913","RA Anatomy - VRvST Study","A Multicentre, Randomised Cross-over Equivalence Trial Investigating Knowledge of Anatomy Following Virtual Reality or Standard Teaching in Novice Anaesthetists","Inclusion Criteria:\n\n* Anaesthetists that are residents in a recognised Royal College of Anaesthetists (RCoA) training program\n* Anaesthetic training grades (Stage 1 - 3).\n\nExclusion Criteria:\n\n* Visual impairment (this does not include wearing glasses\u002Fcontact lenses)\n* History of severe diseases affecting physical motion or balance\n* History of any drugs that may affect physical motion or balance within 12 hours of the intervention\n* Pregnancy\n* Individuals who had consumed alcohol within 24 h of the intervention.\n* Resident doctors not in a recognised RCOA training program e.g. Staff grade anaesthetists",true,{"count":110,"type":20},102,[51],"Primary Objective: Score out of 44 on a validated test of anatomy and sono-anatomy\n\nSecondary Objective:\n\nBefore training\n\n* Handedness (Edinburgh Handedness Inventory)\n* Subjective sleepiness (Karolinska scale)\n* Motor reaction time (Psychomotor Vigilance test)\n* Attention control (Anti-Saccade test)\n* Mental rotation (Mental Rotation Task)\n* Depression Anxiety, Stress (DASS score)\n* Visual Search Task (Divided Attention)\n* Knowledge pretraining\n\nAfter training and testing\n\n* Knowledge after training session\n* Acceptability: Client Satisfaction Questionnaire (CSQ-8)\n* Usability: CyberSickness in Virtual Reality Questionnaire (CSQ-VR)\n* Immersion: Witmer and Singer Presence Questionnaire\n* Subjective workload (NASA - TLX scale)\n* Cognitive Demand Battery (CBD)\n* Resource use: Calculation of cost differences between learning Modalities\n\nStudy population: Resident anaesthetists\n\nRecruitment Target: 102\n\nMethodology:\n\nThis is a non-clinical randomised controlled trial of resident anaesthetists undergoing training in regional anaesthesia. Residents will be randomised to one of two groups for each training session day:\n\n* Standard anatomical training (Group A)\n* Virtual reality based anatomical training. (Group B) Then followed by another training day session and participants will enter either standard or VR teaching depending on the previous allocation:\n* Standard anatomical training (Group B)\n* Virtual reality based anatomical training. (Group A)\n\nAnatomical knowledge will be tested in both groups using an on-line questionnaire developed by the Chief Investigator.\n\nEligibility criteria: Inclusion criteria:\n\n1. Anaesthetists that are residents in a recognised Royal College of Anaesthetists (RCoA) training program\n2. Anaesthetic training grades (Stage 1 - 3).\n\nExclusion criteria:\n\n1. Visual impairment (this does not include wearing glasses\u002Fcontact lenses)\n2. History of severe diseases affecting physical motion or balance\n3. History of any drugs that may affect physical motion or balance within 12 hours of the intervention\n4. Pregnancy\n5. Individuals who had consumed alcohol within 24 h of the intervention.\n6. Resident doctors not in a recognised RCOA training program e.g. Staff grade anaesthetists.\n\nStudy treatment:\n\nStandard teaching - control Virtual reality teaching - intervention",[114,89,115],"Virtual Reality Simulation","Education, Medical",[117,118,119],"Virtual reality","sonoanatomy","regional anaesthesia","2026-01-15",{"date":122,"type":30},"2026-01-23",{"date":124,"type":20},"2026-01-01",{"date":126,"type":20},"2027-01-31",{"name":36,"class":37},""]