[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"SB Istanbul Education and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":153},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,47,73,97,124],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100638728","impact-of-chronic-venous-insufficiency-on-outcomes-after-total-knee-arthroplasty-100638728",false,"NCT07577141","Impact of Chronic Venous Insufficiency on Outcomes After Total Knee Arthroplasty","The Impact of Chronic Venous Insufficiency on Postoperative Outcomes and Wound Healing After Total Knee Arthroplasty: A Prospective Observational Study","VENOUS-TKA","Inclusion Criteria:\n\n* Patients undergoing primary total knee arthroplasty\n* Age ≥ 50 years\n* Ability to provide informed consent\n\nExclusion Criteria:\n\n* Revision TKA\n* Peripheral arterial disease (ABI \\\u003C 0.9)\n* Active infection\n* History of deep vein thrombosis within 6 months\n* Immunosuppressive therapy\n* Severe uncontrolled diabetes mellitus",true,"ALL","50 Years","80 Years",{"count":22,"type":23},100,"ESTIMATED","OBSERVATIONAL","Total knee arthroplasty (TKA) is an effective treatment for end-stage knee osteoarthritis; however, postoperative complications-particularly wound healing problems-remain a significant concern. Chronic venous insufficiency (CVI) is associated with venous hypertension, impaired microcirculation, and tissue hypoxia, which may negatively affect wound healing and increase complication rates.\n\nThis prospective observational cohort study aims to evaluate the impact of preoperative CVI on postoperative outcomes following TKA. Patients will be assessed preoperatively using the CEAP classification and Doppler ultrasonography to identify and stratify venous insufficiency.\n\nParticipants will be followed for 12 months postoperatively. The primary outcome will be wound healing complications in the early postoperative period. Secondary outcomes will include functional outcomes assessed by the Knee Society Score (KSS), patient-reported outcomes using the WOMAC score, and overall complication rates.\n\nThe findings of this study are expected to clarify the role of venous insufficiency as a potential risk factor in TKA and may contribute to improved preoperative risk stratification and postoperative management strategies.",[27,28,29],"Total Knee Anthroplasty","Venous Insufficiency (Chronic)(Peripheral)","Doppler Ultrasound Diagnosis",[31,32,33,34],"total knee arthroplasty","chronic venous insufficiency","doppler","wound","NOT_YET_RECRUITING","2026-05-12",{"date":38,"type":39},"2026-05-18","ACTUAL",{"date":41,"type":23},"2026-06",{"date":43,"type":23},"2027-06",{"name":45,"class":46},"SB Istanbul Education and Research Hospital","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":18,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100626248","ultrasound-evaluation-in-carpal-tunnel-syndrome-100626248","NCT07433166","Ultrasound Evaluation in Carpal Tunnel Syndrome","Prospective Evaluation of Median Nerve Cross-Sectionall Area and Power Doppler Signal Changes in Patients With Carpal Tunnel Syndrome","CTS-PD","Inclusion Criteria:\n\n* clinically and electrophysiologically confirmed carpal tunnel syndrome\n* symptom duration \\> 3 months\n* written informed consent\n\nExclusion Criteria:\n\n* previous wrist surgery\n* cervical radiculopathy\n* inflammatory arthritis\n* pregnancy","18 Years","75 Years",{"count":22,"type":23},"This prospective cohort study aims to evaluate median nerve cross-sectional area and intraneural vascularity using power Doppler ultrasonography in patients with carpal tunnel syndrome. Ultrasonographic findings will be compared between diabetic and non-diabetic patients. Clinical severity and electrophysiological findings will be correlated with ultrasonographic parameters.",[60],"Carpal Tunnel Syndrome (CTS)",[62,63,64],"carpal tunnel","ultrasound","power doppler","2026-04-04",{"date":67,"type":39},"2026-04-09",{"date":69,"type":23},"2026-05",{"date":71,"type":23},"2027-01",{"name":45,"class":46},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":94,"leadSponsor":96,"locationsCount":4},"100632740","condylar-offset-and-outcomes-in-primary-total-knee-arthroplasty-100632740","NCT07517614","Condylar Offset and Outcomes in Primary Total Knee Arthroplasty","Prospective Evaluation of Posterior and Anterior Condylar Offset and Their Impact on Functional Outcomes in Primary Total Knee Arthroplasty","OFFSET-TKA","Inclusion Criteria:\n\n* diagnosis of primary knee osteoarthiritis\n* indication of knee arthroplasty\n* 50-85 years\n* ability t oprovide informed consent and comply with follow up\n\nExclusion Criteria:\n\n* revision knee arthroplasty\n* inflammatory arthritis\n* severe corona deformity (\\>20 varus\u002Fvalgus)\n* previous knee surgery or fracture","85 Years",{"count":22,"type":23},"This prospective cohort study aims to evaluate the effect of posterior condylar offset (PCO) and anterior condylar offset (ACO) changes on functional outcomes after primary total knee arthroplasty (TKA). Standardized imaging and clinical assessment protocols will be used to determine optimal PCO and ACO ranges associated with improved postoperative range of motion, patient-reported outcomes, and reduced anterior knee symptoms.",[85],"Knee Arthritis Osteoarthritis",[87,88,89],"knee osteoarthiritis","anterior condylar offset","posterior condylar offset","2026-04-03",{"date":92,"type":39},"2026-04-08",{"date":69,"type":23},{"date":95,"type":23},"2027-07",{"name":45,"class":46},{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":18,"minAge":55,"maxAge":56,"enrollmentInfo":104,"targetDuration":4,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":114,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":123},"100600091","comparison-of-two-different-regional-anesthetic-methods-in-total-knee-arthroplasty-patients-100600091","NCT07092982","Comparison of Two Different Regional Anesthetic Methods in Total Knee Arthroplasty Patients","Comparison of the Effects of Ultrasound-Guided Adductor Canal Block With iPACK (Space Between the Popliteal Artery and the Posterior Knee Capsule) Block Combination and Suprainguinal Fascia Iliaca Block on Postoperative Pain and Stress Response in Patients Undergoing Total Knee Arthroplasty","Inclusion Criteria:\n\n* Patients undergoing total knee arthroplasty\n* Patients aged 18-75\n* Patients with ASA I-II-III\n\nExclusion Criteria:\n\n* Coagulation disorders\n* Allergy to local anesthetics\n* Liver and renal failure\n* Alcohol and drug addiction\n* Cognitive dysfunction that may prevent pain assessment\n* Systemic or needle insertion site infection\n* Analgesic use for more than 3 months\n* Patient refusal to participate in the study\u002Frefusal to consent\n* Presence of a hematoma, hernia, neoplasm, etc. in the area where the block will be performed\n* Pre-existing neurological deficit\n* Patients with contraindications to nerve block",{"count":105,"type":23},52,"INTERVENTIONAL",[108],"NA","Total Knee Arthroplasty patients are among the orthopedic cases that experience severe postoperative pain. In these cases, pain must be controlled. If pain is not controlled, early mobilization cannot be achieved. This can result in delayed physical therapy, prolonged hospital stays, the development of nosocomial infections, and impaired cognitive function. All of these factors contribute to increased patient care costs. Multimodal analgesia methods are used to control this pain. One of these methods is peripheral nerve blocks. Peripheral nerve blocks provide pain control and reduce the likelihood of opioid use and related side effects such as nausea, vomiting, and constipation. Current studies recommend Adductor Canal Blocks and iPACK (space between the popliteal artery and the posterior knee capsule) blocks for Total Knee Arthroplasty patients. In addition, studies are also being conducted on the application of the Suprainguinal Fascia-Iliaca Block in Total Knee Arthroplasty patients. The differences in postoperative analgesic effects between these methods are a matter of interest. No study has been conducted comparing the effects of these two approaches, which are routinely applied in our clinic and comply with guidelines, on the postoperative stress response. Regional anesthesia provides adequate pain control and has a positive effect on the stress response. The investigators aim to see a similar effect in peripheral nerve blocks. Therefore, comparing the methods that mentioned will contribute to the literature. In this study, the effects of these two different approaches on postoperative stress response and analgesic efficacy will be compared in terms of patients' postoperative opioid consumption, pain at rest and with movement, time to first analgesic need and development of motor block. IL-6 and CRP values will be examined pre-operatively and post-operatively to measure the effects on the stress response.",[111,112,113],"Total Knee Arthroplasty","Ultrasound Guided Supra-inguinal Fascia Iliaca Block","Adductor Canal Block","RECRUITING","2026-03-31",{"date":117,"type":39},"2026-04-06",{"date":119,"type":39},"2025-08-04",{"date":121,"type":23},"2026-07",{"name":45,"class":46},1,{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":130,"eligibilityCriteria":131,"healthyVolunteers":11,"sex":18,"minAge":55,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":106,"phases":135,"briefSummary":136,"conditions":137,"keywords":140,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":145,"lastUpdatePostDateStruct":146,"startDateStruct":148,"completionDateStruct":150,"leadSponsor":152,"locationsCount":4},"100598444","new-intraoperative-nerve-monitoring-device-100598444","NCT07071571","New Intraoperative Nerve Monitoring Device","Evaluation of the Usability and Safety of the Newly Developed Piezoelectric Sensor Intraoperative Nerve Monitoring Device in Thyroid and Parathyroid Surgery: A Pilot Study","IONM","Inclusion Criteria:\n\n* Age 18-70, diagnosis of benign\u002Fmalignant thyroid disease, informed consent\n\nExclusion Criteria:\n\n* History of previous nerve injury, concomitant neurological disorder","70 Years",{"count":134,"type":23},40,[108],"This study is testing a new device developed to protect the recurrent laryngeal nerve, which is at risk of damage during thyroid and parathyroid surgeries.",[138,139],"Thryoid Cancer","parathyrıoid Adenoma",[141,142,143,144],"neuromonitorization","introperative","recurrent nerve","new device","2025-07-16",{"date":147,"type":39},"2025-07-17",{"date":149,"type":23},"2025-08-01",{"date":151,"type":23},"2026-12-01",{"name":45,"class":46},""]