[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"SYSNAV\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":85},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,39,62],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100622853","study-to-evaluate-the-feasibility-of-syde-digital-endpoints-for-monitoring-patients-with-progressive-supranuclear-palsy---richardson-syndrome-psp-r-100622853",false,"NCT07389018","Study to Evaluate the Feasibility of Syde® Digital Endpoints for Monitoring Patients With Progressive Supranuclear Palsy - Richardson Syndrome (PSP-R)","Prospective Longitudinal Monocentric Study to Evaluate the Feasibility of Syde® Digital Endpoints for Monitoring Patients With Progressive Supranuclear Palsy - Richardson Syndrome (PSP-R)","PROSPER-SYDE","Inclusion Criteria:\n\n1.18 years old or older\n\n2.Participants affiliated to, or beneficiary from, a social security.\n\n3.Ambulant patients (i.e. able to walk 10 meters without assistance)\n\n4.Signed informed consent form by the patient himself or, by caregivers if the patient is not capable to fill, date and sign the form due to fine motor function difficulties..\n\n5.Possible or probable PSP-R according to MDS criteria 2017(Hoglinger et al., Mov Disorder, 2017).\n\nExclusion Criteria:\n\n1. Patients with extreme cognitive disorders that limit their understanding of the data collection process (training of device use and 4-week recording periods every 4 months, device return at the end of the study), tests to be performed including eye movement recording (every 8 months), the implication of the study and consent.\n2. Patients who do not tolerate to keep the sensors on their ankles.\n3. Patients who have undergone a surgical procedure or who have experienced recent trauma (within fewer than 6 months) affecting the lower limbs.\n4. A concomitant chronic or acute neurological, endocrine, infectious, allergic, or inflammatory pathology within the 3-week period immediately prior to inclusion.\n5. Patients affected by any other disorder having a significant impact on gait or lower limb function.\n6. Participant covered by a legal protection measure (guardianship, curatorship or safeguarding of justice) or who is unable to express their consent.\n7. Absence of caregiver.","ALL","18 Years",{"count":20,"type":21},30,"ESTIMATED","OBSERVATIONAL","The study aims to assess the feasibility\u002Facceptability of real-world activity monitoring by the Syde® wearable device in PSP-R. The Syde® collected data will be compared to on-site conventional clinical endpoints, including functional capacity and cognitive assessments, as well as core scales assessments.",[25],"Progressive Supranuclear Palsy- Richardson Syndrome (PSP-R)","NOT_YET_RECRUITING","2026-04-21",{"date":29,"type":30},"2026-04-22","ACTUAL",{"date":32,"type":21},"2026-05",{"date":34,"type":21},"2028-03",{"name":36,"class":37},"SYSNAV","INDUSTRY",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":17,"minAge":18,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":49,"conditions":50,"keywords":4,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":38},"100622851","investigating-specific-gait-patterns-in-individuals-living-with-multiple-sclerosis-100622851","NCT07388992","Investigating Specific Gait Patterns in Individuals Living With Multiple Sclerosis","GAIT-MS","Inclusion Criteria:\n\nFor people living with multiple sclerosis (pwMS):\n\n1. Age at inclusion between =18 and =65 years old\n2. Signed informed consent and ability to comply with study and follow-up.\n3. Confirmed MS diagnosis according to McDonald criteria (2017)\n4. Expanded Disability Status Scale EDSS = 6\n5. Stable treatment for 2 months before inclusion (for both disease modifying and symptomatic therapies)\n6. Ability and willingness to participate in and comply with all study procedures defined in the protocol\n7. Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category\n\nFor Healthy volunteers :\n\n1. Age at inclusion between =18 and =65 years old\n2. Signed informed consent and ability to comply with study and follow-up.\n3. Ability and willingness to participate in and comply with all study procedures defined in the protocol\n4. Subject will be eligible for enrollment in this study only if either affiliated to, or a beneficiary of a social security category\n\nExclusion Criteria:\n\nFor pwMS:\n\n1. Participants with a relapse within the past 3 months before the inclusion\n2. Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator\n3. Past or present pathology other than MS or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator\n4. Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.\n\nFor healthy volunteers (HV):\n\n1. Participants with significant cognitive disorders, limiting the understanding of the exercises to be performed or presence of apparent communication difficulties hindering the correct collection of data, as assessed by the investigator\n2. Past or present pathology or surgery or trauma impacting gait, ambulatory function or upper limb function, as assessed by the investigator\n3. Vulnerable adults: individuals subject to a legal protection measure (guardianship, limited guardianship, or judicial protection) or unable to express their consent.",true,"65 Years",{"count":20,"type":21},"The study aims to investigate specific ambulation patterns characteristic of the quality of gait in people with MS (pwMS)",[51,52],"Multiple Sclerosis","Healthy Adult","RECRUITING","2026-03-20",{"date":56,"type":30},"2026-03-23",{"date":58,"type":30},"2026-03-16",{"date":60,"type":21},"2026-06",{"name":36,"class":37},{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":11,"sex":17,"minAge":70,"maxAge":47,"enrollmentInfo":71,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":53,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":38},"100622849","prospective-longitudinal-monocentric-study-to-measure-limb-movement-in-patients-with-fgfr3-related-skeletal-dysplasia-100622849","NCT07388966","Prospective Longitudinal Monocentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia","Prospective Longitudinal Monocentric Study to Measure Limb Movement in Patients With FGFR3-related Skeletal Dysplasia Using Syde®","SKY-MOT3","Inclusion Criteria:\n\n1. Aged 3 years old or older at the time of consent.\n2. Written informed consent obtained:\n\n   1. From the parent(s) or legal guardian(s) for participants under 18 years old.\n   2. From participants 18 years old and older.\n3. Affiliated to, or beneficiary of a social security category\n4. Able to walk unassisted for at least 10 meters.\n5. Genetically confirmed diagnosis with one pathogenic variant (ACMG class IV \\& V) of achondroplasia or hypochondroplasia.\n6. Participant (and caregivers for participants under 18 years old) willing and able to comply with all study procedures including: questionnaires, Syde® related procedures\n\nExclusion Criteria:\n\n1. Subjects who have short stature condition other than ACH\u002FHCH.\n2. Presence of cognitive disorders that limit their understanding of the data collection process (training of device use and 4-week recording periods every 6 months, device return at the end of the study), the implication of the study and consent.\n3. Presence or history of any concurrent disease or condition that could interfere with study participation, impact pediatric growth, affect motor or balance or gait function (such as neurological, endocrine, infectious, allergic, osteoarthritis, or inflammatory), assessed by the investigator.\n4. Females who are pregnant, or planning to become pregnant during the study duration.\n5. Body Mass Index = 35 kg\u002Fm2.\n6. Recent upper and\u002For lower limbs injury (trauma\u002Ffracture or surgery) in the 6 months preceding inclusion.\n7. Prior limb lengthening surgery or planned or expected to have limb lengthening surgery while enrolled in the study.\n8. Presence of guided growth hardware (such as 8-plates) or planned orthopedic surgeries during the study.\n9. Vulnerable patient (guardianship, curatorship or safeguarding of justice), unable to provide informed consent or who is unable to express their consent.","3 Years",{"count":72,"type":21},40,"The study aims to identify which Syde®-derived digital outcomes are reliable in FGFR3-related Skeletal Dysplasia. This requires to set-up a natural history study to measure limb movements in patients with ACH or HCH.",[75,76],"Achondroplasia","Hypochondroplasia","2026-02-18",{"date":79,"type":30},"2026-02-20",{"date":81,"type":30},"2026-02-06",{"date":83,"type":21},"2028-02",{"name":36,"class":37},""]