[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Saglik Bilimleri Universitesi\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":620},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,101,0,25,[9,50,74,98,123,144,166,200,231,257,283,306,333,352,380,396,422,449,465,492,519,545,562,579,601],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100054173","maternal-periodontal-inflammation-and-pregnancy-outcomes-salivary-and-amniotic-biomarkers-100054173",false,"NCT07699978","Maternal Periodontal Inflammation and Pregnancy Outcomes: Salivary and Amniotic Biomarkers","The Relationship Between Maternal Periodontal Inflammation and Pregnancy Outcomes: Evaluation Using Inflammatory and Oxidative Stress Biomarkers in Saliva and Amniotic Fluid","Inclusion Criteria:\n\nPregnant women between 28 and 32 weeks of gestation Age 18 to 40 years Singleton pregnancy Systemically healthy Normal gestational diabetes screening (oral glucose tolerance test within the hospital reference range) Receiving only routine prenatal vitamin and iron supplementation (no therapeutic medications) Low-risk pregnancy No history of chorioamnionitis No periodontal treatment within the previous 6 months Able and willing to provide written informed consent\n\nExclusion Criteria:\n\nMultiple pregnancy Use of antibiotics or anti-inflammatory medications during pregnancy Current smoking or alcohol consumption Presence of an acute infection Placental pathology Major fetal anomaly High-risk pregnancy as determined by the obstetrician Refusal or inability to provide informed consent",true,"FEMALE","18 Years","40 Years",{"count":22,"type":23},80,"ESTIMATED","OBSERVATIONAL","Periodontal disease is a chronic inflammatory condition that affects the tissues supporting the teeth and may contribute to systemic inflammation and oxidative stress. Increasing evidence suggests that maternal inflammation during pregnancy may be associated with adverse pregnancy outcomes, including preterm birth. However, the biological mechanisms linking maternal periodontal inflammation to the intrauterine environment remain unclear.\n\nThis prospective observational cohort study aims to investigate the relationship between maternal periodontal status and inflammatory and oxidative stress biomarkers measured in both saliva and amniotic fluid. Eighty healthy pregnant women between 28 and 32 weeks of gestation will be recruited from the Obstetrics and Gynecology Clinic of Gulhane Training and Research Hospital. Participants will undergo a comprehensive periodontal examination and provide unstimulated saliva samples. Amniotic fluid samples will be collected during delivery as part of routine obstetric care, without any additional invasive procedures.\n\nThe concentrations of 8-hydroxy-2'-deoxyguanosine (8-OHdG), malondialdehyde (MDA), interleukin-6 (IL-6), and matrix metalloproteinase-8 (MMP-8) will be measured in saliva and amniotic fluid using enzyme-linked immunosorbent assay (ELISA). Pregnancy outcomes, including gestational age at delivery, birth weight, and pregnancy complications, will also be recorded.\n\nThe study will evaluate whether maternal periodontal inflammation is associated with changes in inflammatory and oxidative stress biomarkers in saliva and amniotic fluid and whether these biomarkers are related to pregnancy outcomes. The findings may improve understanding of the biological relationship between oral health and pregnancy and may contribute to the identification of biomarkers associated with adverse pregnancy outcomes.",[27,28,29],"Periodontal Disease","Pregnancy","Preterm Birth",[31,28,29,32,33,34,35,36,37],"Periodontitis","Oxidative Stress","Inflammation","Saliva","Amniotic Fluid","8-Hydroxy-2'-deoxyguanosine (8-OHdG)","Interleukin-6 (IL-6)","NOT_YET_RECRUITING","2026-07-07",{"date":41,"type":42},"2026-07-13","ACTUAL",{"date":44,"type":23},"2026-08-20",{"date":46,"type":23},"2027-08-15",{"name":48,"class":49},"Saglik Bilimleri Universitesi","OTHER",{"id":51,"slug":52,"hasResults":12,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100644035","game-based-psychological-first-aid-training-for-midwifery-students-100644035","NCT07669480","Game-Based Psychological First Aid Training for Midwifery Students","The Effect of Game-Based Learning-Based Psychological First Aid Training on the Self-Efficacy and Problem-Solving Levels of Midwifery Students","Inclusion Criteria:\n\n* Volunteering to participate in the research.\n* Having internet access.\n* Having a smartphone.\n* Having taken the emergency care and first aid course.\n* Being an active 2nd-year student in the Midwifery Department of Hamidiye Faculty of Health Sciences, Health Sciences University.\n\nExclusion Criteria:\n\n* Being a passive student in the 2nd year of the Midwifery Department at Hamidiye Faculty of Health Sciences, Health Sciences University.\n* Not participating in educational practices.",{"count":58,"type":23},84,"INTERVENTIONAL",[61],"NA","Purpose:\n\nThis study aims to evaluate the effects of an educational digital escape room game-based Psychological First Aid (PFA) training on the PFA self-efficacy and problem-solving levels of undergraduate midwifery students.\n\nMethods:\n\nThe study will be conducted as a randomized controlled trial with a pretest, posttest, and follow-up design at the Health Sciences University (SBU), Hamidiye Faculty of Health Sciences, Department of Midwifery during the spring semester of the 2025-2026 academic year. Second-year midwifery students will be randomly assigned to either the intervention group or the control group using a stratified randomization method based on their Grade Point Average (GPA).\n\nBoth groups will receive a standardized theoretical PFA training program. In addition to this training, the intervention group will participate in an interactive digital escape room game developed on the Genially platform, consisting of short web-based scenarios under 20 minutes. The control group will receive only the standard theoretical education. Data will be collected at baseline (Week 1), post-intervention (Week 3), and during follow-up phases using the Psychological First Aid Self-Efficacy Scale and the Problem Solving Inventory to compare the behavioral and educational outcomes between the two groups.",[64,65],"Digital Escape Room","Game-Based Learning","2026-06-22",{"date":68,"type":42},"2026-06-25",{"date":70,"type":23},"2026-06-15",{"date":72,"type":23},"2026-07-15",{"name":48,"class":49},{"id":75,"slug":76,"hasResults":12,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":12,"sex":81,"minAge":4,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":59,"phases":84,"briefSummary":85,"conditions":86,"keywords":88,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":96,"leadSponsor":97,"locationsCount":4},"100641204","the-effect-of-simulation-based-interprofessional-education-on-attitudes-toward-teamwork-100641204","NCT07655752","THE EFFECT OF SIMULATION-BASED INTERPROFESSIONAL EDUCATION ON ATTITUDES TOWARD TEAMWORK","THE EFFECT OF SIMULATION-BASED INTERPROFESSIONAL EDUCATION ON TEAMWORK ATTITUDES AMONG NURSING AND PARAMEDIC STUDENTS","Inclusion Criteria:\n\nNursing Student:\n\n* Be a 4th-year (senior) student in a bachelor's degree program in nursing\n* Have completed an emergency department rotation as part of the Clinical Practice I course and have finished the emergency department internship\n* Having previously participated in a simulation-based practice\n\nParamedic Student:\n\n* Be a second-year (final-year) student in the paramedic associate degree program\n* Since the emergency department internship is completed in the first year, have completed the first-year summer internship of the Paramedic Program\n* Have taken the Professional Practice-I course\n* Having previously participated in a simulation-based practice\n\nExclusion Criteria:\n\nParamedic and nursing students:\n\n* Must be a graduate of a vocational high school for health professions,\n* Must have worked or currently be working in the field as a nurse or emergency medical technician\n* Having previously participated in an interprofessional simulation-based practice.","ALL",{"count":83,"type":23},56,[61],"Our study aims to evaluate the effect of interprofessional simulation-based learning on teamwork attitudes among nursing and paramedic students during the patient handover process. The study sample consists of fourth-year (senior) students from the Gülhane Faculty of Nursing at the University of Health Sciences and second-year (senior) students from the Paramedic Program at the School of Health Professions. In this study, the intervention will be conducted in two phases: the preparation phase and the implementation phase.",[87],"No Specific Diseases or Conditions Are Being Studied",[89,90,91],"Simulation","Interdisciplinary Education","Teamwork","2026-06-18",{"date":94,"type":42},"2026-06-23",{"date":70,"type":23},{"date":72,"type":23},{"name":48,"class":49},{"id":99,"slug":100,"hasResults":12,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":12,"sex":81,"minAge":20,"maxAge":4,"enrollmentInfo":105,"targetDuration":4,"studyType":59,"phases":107,"briefSummary":108,"conditions":109,"keywords":111,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100641196","the-effects-of-tele-rehabilitation-based-dual-task-upper-extremity-training-in-patients-with-parkinsons-disease-100641196","NCT07641556","The Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease","Investigating the Effects of Tele-Rehabilitation-Based Dual-Task Upper Extremity Training in Patients With Parkinson's Disease","Inclusion Criteria:\n\n* Having been diagnosed with Parkinson's disease by a neurologist according to the UK Brain Bank criteria\n* Being in stage 3 or higher according to the Hoehn-Yahr Scale\n* Having a caregiver capable of providing the necessary assistance during tele-rehabilitation sessions and using the required equipment and programs.\n* Having the device and software to conduct remote video calls for tele-rehabilitation\n\nExclusion Criteria:\n\n* Presence of a neurological disease other than Parkinson's disease\n* Cognitive impairment (Standardized Mini Mental Test score less than 24)\n* Having undergone deep brain stimulation surgery\n* Having a visual, auditory, or perceptual problem\n* Having any orthopedic, rheumatological, or other condition that may affect hand functions",{"count":106,"type":23},40,[61],"The aim of this study is to compare the effects of tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training with clinical based dual-task upper extremity training and conventional single-task upper extremity training in patients with Parkinson's disease. The main questions it aims to answer are:\n\n* Whether there are differences in motor symptoms, hand dexterity, upper extremity functions, grip strength, executive functions, daily living activities, and treatment satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training, clinical-based dual-task upper extremity training, and conventional single-task upper extremity training in patients with Parkinson's disease.\n* Whether there is a difference in telemedicine satisfaction between tele-rehabilitation-based synchronous and asynchronous dual-task upper extremity training in patients with Parkinson's disease.\n\nResearchers will compare conventional single-task upper extremity training, clinical-based dual-task upper extremity training, tele-rehabilitation-based synchronous upper extremity training and tele-rehabilitation-based asynchronous upper extremity training.\n\nParticipants will:\n\n* Receive upper extremity exercise training at the study clinic or home, twice a week for approximately 60 minutes each time, for 6 weeks.\n* Participate in assessments at the study clinic before and after exercise training.",[110],"Parkinson's Disease (PD)",[112,113,114,115],"Parkinson's Disease","Dual Task Training","Upper Extremity","Tele-Rehabilitation","2026-06-16",{"date":92,"type":42},{"date":119,"type":23},"2026-07-01",{"date":121,"type":23},"2026-09-15",{"name":48,"class":49},{"id":124,"slug":125,"hasResults":12,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":12,"sex":81,"minAge":20,"maxAge":4,"enrollmentInfo":130,"targetDuration":4,"studyType":59,"phases":132,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":139,"startDateStruct":140,"completionDateStruct":141,"leadSponsor":142,"locationsCount":143},"100641386","comparison-of-two-different-dual-task-training-methods-in-patients-with-parkinsons-disease-100641386","NCT07641569","Comparison of Two Different Dual-Task Training Methods in Patients With Parkinson's Disease","Comparison of Motor-Motor and Cognitive-Motor Dual-Task Training in Patients With Parkinson's Disease","Inclusion Criteria:\n\n* Having been diagnosed with Parkinson's disease by a neurologist according to the UK Brain Bank criteria.\n* Being in stages 1-3 according to the Hoehn-Yahr Scale.\n\nExclusion Criteria:\n\n* Presence of a neurological disease other than Parkinson's disease\n* Cognitive impairment (Standardized Mini Mental Test score less than 24)\n* Having undergone deep brain stimulation surgery\n* Having a visual, auditory, or perceptual problem\n* Having any orthopedic, rheumatological, or other condition that may affect walking and balance.",{"count":131,"type":23},39,[61],"The aim of this study is to compare the effectiveness of motor-motor dual-task training and cognitive-motor dual-task training in patients with Parkinson's disease.The main questions it aims to answer are:\n\n\\- Whether there is a difference between motor-motor dual-task training and cognitive-motor dual-task training in patients with Parkinson's disease in terms of their effects on motor symptoms, balance, gait, functional mobility, activities of daily living, dual-task activities, cognitive functions, and balance confidence.\n\nResearchers will compare single-task training, motor-motor dual task training and cogvitive-motor dual task training.\n\nParticipants will:\n\n* Receive exercise training at the study clinic twice a week for approximately 45 minutes each time, for 6 weeks.\n* Participate in assessments at the study clinic before and after exercise training.",[110],[112,113,136,137],"Motor-Motor","Cognitive-Motor","RECRUITING",{"date":92,"type":42},{"date":70,"type":42},{"date":121,"type":23},{"name":48,"class":49},1,{"id":145,"slug":146,"hasResults":12,"nctId":147,"briefTitle":148,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":4,"enrollmentInfo":150,"targetDuration":4,"studyType":59,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":162,"completionDateStruct":163,"leadSponsor":165,"locationsCount":143},"100641252","the-effect-of-breastfeeding-education-using-the-pecha-kucha-technique-on-breastfeeding-self-efficacy-and-breastfeeding-success-in-the-early-postpartum-period-a-randomized-controlled-trial-100641252","NCT07655765","The Effect of Breastfeeding Education Using the Pecha Kucha Technique on Breastfeeding Self-Efficacy and Breastfeeding Success in the Early Postpartum Period: A Randomized Controlled Trial","Inclusion Criteria:\n\n* \\- Being primiparous\n* Having a full-term, singleton birth\n* Having a healthy newborn\n* Having a spontaneous vaginal birth\n\nExclusion Criteria:\n\n* Being multiparous (having given birth more than once)\n* Having given birth preterm or postterm\n* Having a mother or newborn with health problems\n* Having had a multiple pregnancy\n* Having had a cesarean section",{"count":151,"type":23},128,[61],"Breast milk is considered the most biologically appropriate source of nutrition, essential for the healthy growth and development of newborns. Thanks to its optimal nutrients, immunological factors, and growth regulators, it not only meets nutritional needs but also protects against infections, reducing neonatal morbidity and mortality rates. The Pecha Kucha presentation technique keeps presentations concise and dynamic, creating a fast-paced, light, and engaging experience. It minimizes distractions and maximizes engagement. Because there is no text to read in the Pecha Kucha technique, presenters are required to be more prepared and strive to create a coherent narrative, resulting in a flawless narrative. Thus, the aim is to ensure the success and effectiveness of breastfeeding education with this technique, and ultimately, to promote breastfeeding education using the Pecha Kucha technique to healthcare professionals. The population of this randomized, controlled experimental study consists of primiparous postpartum women who gave birth in the Obstetrics Department of the Physical Therapy Annex Building of the Gaziosmanpaşa Training and Research Hospital at the University of Health Sciences. A power analysis was conducted using the G\\*Power package program, Version 3.1.9.4, to determine the sample size of the study. Because no similar research was found in the literature, Cohen's medium effect size was chosen as the effect size, anticipating that tests assessing the difference between two independent groups would be used when examining the differences in variables between the control and intervention groups. Accordingly, with 64 participants in the control group and 64 in the intervention group, a power of 80% was calculated at a significance level of 0.5 (medium) effect size and 0.05, and a minimum sample size of 128 was determined. The study, planned using an experimental design, is planned to be conducted on two groups: an intervention and a control group. Within the scope of the study, pretest data will be collected by administering the Breastfeeding Self-Efficacy Scale and the LATCH Breastfeeding Diagnostic and Assessment Scale, along with an introductory information form, to postpartum women who agree to participate in the study.",[155],"Pecha Kuka",[157,158,159],"pecha kucha","breast feeding","postpartum period","2026-06-13",{"date":92,"type":42},{"date":160,"type":23},{"date":164,"type":23},"2026-12-01",{"name":48,"class":49},{"id":167,"slug":168,"hasResults":12,"nctId":169,"briefTitle":170,"officialTitle":171,"acronym":172,"eligibilityCriteria":173,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":174,"enrollmentInfo":175,"targetDuration":4,"studyType":59,"phases":176,"briefSummary":177,"conditions":178,"keywords":182,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":143},"100637800","multimodal-fascial-plane-block-for-postoperative-analgesia-in-isolated-cabg-surgery-100637800","NCT07587320","Multimodal Fascial Plane Block for Postoperative Analgesia in Isolated CABG Surgery","Effect of Induction-Time Multimodal Fascial Plane Block on Postoperative Analgesia and Opioid Consumption in Patients Undergoing Isolated Coronary Artery Bypass Grafting: A Prospective Randomized Controlled Trial","BLOCKCABG","Inclusion Criteria:\n\n* Age between 18 and 80 years\n* Scheduled for elective isolated coronary artery bypass grafting (CABG) with saphenous vein graft harvesting\n* ASA physical status II-IV\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known coagulopathy or contraindication to regional anesthesia\n* Use of anticoagulant therapy precluding regional block\n* Known allergy to local anesthetics\n* Local infection at planned block sites\n* Chronic opioid use or chronic pain syndrome\n* Emergency surgery\n* Redo sternotomy\n* Severe neurological disorder affecting pain assessment","80 Years",{"count":83,"type":23},[61],"Postoperative pain following coronary artery bypass grafting (CABG) via median sternotomy remains a significant clinical problem and is associated with increased opioid consumption and postoperative complications. Fascial plane blocks have emerged as part of multimodal analgesia strategies in cardiac surgery.\n\nThis prospective, randomized, controlled, single-blinded study aims to evaluate the effect of an induction-time multimodal fascial plane block package-consisting of bilateral superficial parasternal block, bilateral serratus anterior plane block, and adductor canal block-on postoperative analgesia, opioid consumption, and clinical outcomes in patients undergoing elective isolated CABG with saphenous vein graft harvesting.\n\nPatients will be randomized in a 1:1 ratio to receive either the multimodal fascial plane block package in addition to standard postoperative analgesia or standard postoperative analgesia alone. The primary outcome is total opioid consumption within the first 24 postoperative hours. Secondary outcomes include pain scores, time to first opioid requirement, extubation time, postoperative pulmonary complications, atrial fibrillation, and length of ICU and hospital stay.",[179,180,181],"Coronary Artery Bypass Graft (CABG)","Postoperative Pain","Sternotomy",[183,184,185,186,187,188,189,190,191],"Parasternal Block","Serratus Anterior Plane Block","Adductor Canal Block","Opioid Consumption","Multimodal Analgesia","Randomized Controlled Trial","Cardiac Surgery","Fascial Plane Block","Coronary Artery Bypass Graft","2026-05-12",{"date":194,"type":42},"2026-05-14",{"date":196,"type":42},"2026-01-01",{"date":198,"type":23},"2026-09",{"name":48,"class":49},{"id":201,"slug":202,"hasResults":12,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":4,"eligibilityCriteria":206,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":207,"enrollmentInfo":208,"targetDuration":4,"studyType":59,"phases":210,"briefSummary":211,"conditions":212,"keywords":217,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":143},"100640077","trauma-informed-yoga-intervention-in-young-women-100640077","NCT07589777","Trauma-Informed Yoga Intervention in Young Women","Trauma-Informed Yoga Intervention: A Randomized Controlled Trial on Psychological Trauma, Emotion Regulation, and Interoceptive Awareness in Young Adult Women","Inclusion Criteria:\n\n* Being a woman aged 18-25 years\n* Providing voluntary written informed consent after being informed about the study\n* Scoring within the highest 25th percentile on the Transmitted Psychological Trauma Scale based on the pre-screening assessment, indicating high levels of trauma-related symptoms\n* Having no physical limitations that would prevent participation in weekly sessions and being medically eligible to engage in yoga practices\n* Agreeing to comply with the study protocol, including attendance at intervention sessions and completion of all assessments\n\nExclusion Criteria:\n\n* Inability to provide reliable responses due to the presence of active psychotic disorder, bipolar disorder, or severe cognitive impairment\n* Being in an acute psychological crisis\n* Initiation of intensive psychotherapy targeting trauma symptoms (e.g., trauma-focused therapy) within the past 3 months or participation in a similar structured psychosocial intervention during the study period\n* Presence of serious musculoskeletal, cardiovascular, or neurological conditions or injuries that would prevent participation in yoga, or medical restriction of physical activity by a physician\n* Having an established regular practice of yoga or meditation","25 Years",{"count":209,"type":23},46,[61],"The aim of this study is to evaluate the effects of a trauma-informed yoga intervention on psychological trauma symptoms, difficulties in emotion regulation, and interoceptive awareness in young adult women.",[213,214,215,216],"Trauma","Young Adult Females","Awareness","Emotional Regulation",[218,219,220,221,222],"trauma-informed yoga","emotion regulation","interoceptive awareness","psychological trauma","randomized controlled trial","2026-05-09",{"date":225,"type":42},"2026-05-15",{"date":227,"type":23},"2026-06-01",{"date":229,"type":23},"2026-11-30",{"name":48,"class":49},{"id":232,"slug":233,"hasResults":12,"nctId":234,"briefTitle":235,"officialTitle":236,"acronym":4,"eligibilityCriteria":237,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":238,"targetDuration":4,"studyType":59,"phases":239,"briefSummary":240,"conditions":241,"keywords":246,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":252,"startDateStruct":253,"completionDateStruct":254,"leadSponsor":256,"locationsCount":143},"100637653","prenatal-yoga-intervention-in-pregnant-women-100637653","NCT07585916","Prenatal Yoga Intervention in Pregnant Women","Effects of a Prenatal Yoga Intervention on Traumatic Childbirth Perception, Self-Perception, and Delivery Preferences in Pregnant Women","Inclusion Criteria:\n\n* Being at or beyond the 16th week of gestation (second trimester or later)\n* Being aged 18 years or older\n* Having no diagnosis of high-risk pregnancy based on obstetric evaluation\n* Having no medical restriction on physical activity or yoga practice as determined by a physician\n* Providing written informed consent after being informed about the study\n\nExclusion Criteria:\n\n* Diagnosis of high-risk pregnancy (e.g., preeclampsia, placenta previa, premature rupture of membranes, risk of preterm birth, or other serious obstetric complications)\n* Physician-imposed restriction on physical activity\n* Presence of serious systemic conditions that would prevent participation in yoga practice\n* Inability to complete the questionnaires reliably due to psychiatric or cognitive conditions\n* Declining to participate or not providing informed consent",{"count":209,"type":23},[61],"The aim of this study is to determine the effects of a prenatal yoga intervention on traumatic childbirth perception, self-perception, and delivery preferences in pregnant women.",[242,243,213,244,245],"Pregnant Women","Prenatal Yoga","Body Image","Delivery",[247,248,249,250,251],"perception of traumatic childbirth","body image","preferred mode of delivery","pregnant women","prenatal yoga",{"date":194,"type":42},{"date":225,"type":23},{"date":255,"type":23},"2026-12-30",{"name":48,"class":49},{"id":258,"slug":259,"hasResults":12,"nctId":260,"briefTitle":261,"officialTitle":262,"acronym":263,"eligibilityCriteria":264,"healthyVolunteers":17,"sex":81,"minAge":265,"maxAge":266,"enrollmentInfo":267,"targetDuration":4,"studyType":59,"phases":269,"briefSummary":270,"conditions":271,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":276,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":4},"100636155","investigation-of-allergen-sensitization-in-newborn-babies-diagnosed-with-necrotizing-enterocolitis-100636155","NCT07562009","Investigation of Allergen Sensitization in Newborn Babies Diagnosed With Necrotizing Enterocolitis.","Allergy Risk and Sensitization Following Necrotizing Enterocolitis","AlisNEC","Inclusion Criteria:\n\n1. Infants born in our hospital and diagnosed with NEC during the study period.\n2. Age-matched control infants born in our hospital during the same period but without NEC diagnosis.\n3. Written and verbal informed consent obtained from at least one parent.\n\n   \\-\n\nExclusion Criteria:\n\n1. Infants whose parents did not provide written or verbal consent.\n2. Infants with major congenital anomalies.\n3. Infants with chromosomal disorders.\n4. Infants with gastrointestinal malformations (e.g., duodenal atresia, gastroschisis, omphalocele).\n5. Infants diagnosed with immunodeficiency. -","12 Months","24 Months",{"count":268,"type":23},130,[61],"To evaluate the frequency of allergy between 12 and 24 months of age in infants who were treated in the neonatal clinic and had NEC. To investigate the relationship between NEC development and the development of allergy in the later period.",[272,273,274],"Necrotizing Enterocolitis","Allergy","Preterm","2026-04-24",{"date":277,"type":42},"2026-05-01",{"date":279,"type":23},"2026-04-01",{"date":281,"type":23},"2028-01-01",{"name":48,"class":49},{"id":284,"slug":285,"hasResults":12,"nctId":286,"briefTitle":287,"officialTitle":288,"acronym":4,"eligibilityCriteria":289,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":290,"enrollmentInfo":291,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":293,"conditions":294,"keywords":297,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":300,"startDateStruct":302,"completionDateStruct":303,"leadSponsor":305,"locationsCount":4},"100635744","effect-of-high-level-headphone-sound-exposure-on-exercise-responses-in-young-healthy-individuals-100635744","NCT07556666","Effect of High-Level Headphone Sound Exposure on Exercise Responses in Young Healthy Individuals","The Effect of High-Level Headphone Sound Exposure on Cardiorespiratory Responses and Perceived Exertion","Inclusion Criteria:\n\n* Healthy adults aged 18 to 30 years\n* Male or female participants\n* No regular exercise habit\n* Voluntary participation with written informed consent\n\nExclusion Criteria:\n\n* Any cardiopulmonary, neurological, or musculoskeletal disease\n* Any acute cardiovascular, respiratory, or musculoskeletal complaint\n* Infection, fever, dizziness, fatigue, or similar temporary health problem on the test day\n* Alcohol consumption within 12 hours before testing\n* Caffeine consumption within 3 hours before testing\n* Vigorous physical activity within 24 hours before testing\n* Inability to complete the exercise protocol or withdrawal from the study","30 Years",{"count":292,"type":23},38,"This study will investigate the effect of high-level headphone sound exposure on cardiorespiratory responses and perceived exertion during a submaximal treadmill exercise test in young healthy individuals. Healthy volunteers aged 18 to 30 years will complete two exercise sessions under two different conditions: zero-sound and high-level sound exposure. Heart rate, oxygen saturation, blood pressure, and perceived exertion will be evaluated before, during, and after exercise.",[295,296],"Sound Exposure","Exercise Performance",[298,299],"Noise","Exercise",{"date":301,"type":42},"2026-04-29",{"date":277,"type":23},{"date":304,"type":23},"2027-05-01",{"name":48,"class":49},{"id":307,"slug":308,"hasResults":12,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":4,"eligibilityCriteria":312,"healthyVolunteers":17,"sex":81,"minAge":4,"maxAge":4,"enrollmentInfo":313,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":315,"conditions":316,"keywords":319,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":275,"lastUpdatePostDateStruct":326,"startDateStruct":328,"completionDateStruct":330,"leadSponsor":332,"locationsCount":143},"100613065","clinical-evaluation-of-customized-attachment-composites-in-clear-aligner-therapy-100613065","NCT07261735","Clinical Evaluation of Customized Attachment Composites in Clear Aligner Therapy","Three-Dimensional Evaluation of Wear and Clinical Survival of Attachments Reproduced With Customized Composites for Clear Aligner Therapy: A Prospective Observational Clinical Study","Inclusion Criteria:\n\n* Fully erupted permanent dentition.\n* No existing prosthetic restorations.\n* Mild-to-moderate dental crowding or spacing (2-6 mm).\n* Patients who are scheduled to undergo clear aligner therapy at the Department of Orthodontics, Gülhane Faculty of Dentistry, between 01.08.2025 and 01.08.2026.\n* Patients who agree to participate and provide informed consent.\n\nExclusion Criteria:\n\n* History of previous fixed orthodontic treatment.\n* Patients with poor predicted compliance or low cooperation.\n* Presence of severe or generalized periodontal disease.\n* High caries incidence or untreated caries.\n* Poor oral hygiene\n* Habitual consumption of hard foods.\n* Bruxism\n* Congenitally missing permanent teeth.\n* Dental developmental anomalies.\n* Teeth with existing composite resin restorations or ceramic crowns on buccal surfaces (which may interfere with attachment bonding or wear analysis)",{"count":314,"type":23},24,"This prospective observational clinical study aims to evaluate the three-dimensional surface wear and clinical survival of orthodontic attachments fabricated with customized composite materials used in clear aligner therapy. Attachments play a critical role in the biomechanical efficiency of aligner treatment by facilitating planned tooth movements. However, the mechanical and surface properties of the composites used for attachment fabrication may affect their wear behavior and long-term stability.\n\nIn this study, four different composite materials will be tested using a split-mouth design in patients treated with clear aligners. Each quadrant will receive a different composite, including both customized and universal types. All attachments will be fabricated using standardized digital templates and bonded under identical clinical conditions. Surface wear will be evaluated using three-dimensional optical scanning and metrology software at baseline, 1 week, 1 month, 3 months, and 6 months. Lost attachments will be replaced and recorded but excluded from wear analysis.\n\nThe results of this study are expected to provide valuable insights into the optimal material selection for clear aligner attachments, improving treatment accuracy and clinical durability.",[317,318],"Clear Aligner Therapy","Aligner Attachment Wear",[320,321,322,323,324,325],"Clear aligner therapy","Orthodontic attachments","Split-mouth design","Customized composites","Surface wear","Clinical survival",{"date":327,"type":42},"2026-04-30",{"date":329,"type":42},"2025-08-25",{"date":331,"type":23},"2026-08",{"name":48,"class":49},{"id":334,"slug":335,"hasResults":12,"nctId":336,"briefTitle":337,"officialTitle":337,"acronym":4,"eligibilityCriteria":338,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":339,"enrollmentInfo":340,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":342,"conditions":343,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":347,"startDateStruct":349,"completionDateStruct":350,"leadSponsor":351,"locationsCount":143},"100634613","investigation-of-the-effect-of-screen-time-before-sleep-on-posture-disorders-and-dynamic-balance-100634613","NCT07541963","Investigation of the Effect of Screen Time Before Sleep on Posture Disorders and Dynamic Balance","Inclusion Criteria:\n\n* Healthy adults\n* Aged 18 to 35 years\n* Willing to participate voluntarily in the study\n\nExclusion Criteria:\n\n* History of orthopedic injury or surgery affecting balance\n* Use of medications that may affect attention or balance\n* Refusal to provide informed consent","35 Years",{"count":341,"type":23},34,"The widespread use of electronic devices such as smartphones, tablets, and laptops has significantly increased screen exposure, especially before sleep. Prolonged screen use may contribute to poor posture by promoting forward head posture, rounded shoulders, and other musculoskeletal problems. In addition, screen exposure before sleep may negatively affect sleep quality and neuromuscular performance, which may in turn influence postural control and balance.",[344,345],"Postural Disorders","Balance Problems","2026-04-22",{"date":348,"type":42},"2026-04-27",{"date":277,"type":23},{"date":304,"type":23},{"name":48,"class":49},{"id":353,"slug":354,"hasResults":12,"nctId":355,"briefTitle":356,"officialTitle":357,"acronym":358,"eligibilityCriteria":359,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":360,"enrollmentInfo":361,"targetDuration":4,"studyType":59,"phases":363,"briefSummary":364,"conditions":365,"keywords":370,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":376,"startDateStruct":377,"completionDateStruct":378,"leadSponsor":379,"locationsCount":143},"100635966","act-based-group-therapy-and-mobile-application-intervention-for-emotional-eating-100635966","NCT07559552","ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating","The Effect of Acceptance and Commitment Therapy and a Mobile App on Emotional Eating, Emotion Regulation, and Psychological Flexibility in Overweight Individuals","ACT-EE","Inclusion Criteria:\n\n* Agreeing to participate in the study,\n* Being between 18-65 years of age,\n* Having a body mass index ≤ 25 (BMI ≤ 29.9),\n* Being able to read and write,\n* Having an iOS or Android smartphone,\n* Having internet access,\n* Having a home environment suitable for online sessions (having a computer\u002Fsmartphone, internet access at home, the patient being able to be alone in the room during the session, etc.),\n\nExclusion Criteria:\n\n* Having communication problems that would prevent the interview,\n* Having a diagnosis of a mental disorder, including an eating disorder, that would prevent participation in the study, or having concomitant serious medical conditions that could potentially jeopardize study participation.\n* Having undergone bariatric surgery. • Being on the waiting list for bariatric surgery.\n* Being pregnant, breastfeeding, or planning to become pregnant within the next 6 months.\n* Receiving therapy\u002Fcounseling for emotional eating and emotion regulation problems,\n* Using a mobile application for emotional eating and emotion regulation problems,","65 Years",{"count":362,"type":23},78,[61],"This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in overweight individuals. Emotional eating is a condition in which individuals frequently use eating behavior as a coping mechanism for negative emotions.\n\nParticipants will be randomly assigned to intervention groups receiving ACT-based group therapy, ACT-based group therapy combined with an ACT-based mobile app, or a control group. The intervention will last six weeks and will include structured group sessions as well as mobile-based exercises, reminders, and coping strategies.\n\nOutcome measures will include emotional eating, emotion regulation, and psychological flexibility. Assessments will be conducted at baseline, post-intervention, and during the follow-up phase. The findings of this study are expected to contribute to the development of accessible and effective interventions for emotional eating.",[366,367,368,369],"Emotional Eating","Emotion Regulation","Overweight","Psychological Flexibility",[371,366,367,369,372,373,374,368,375],"Acceptance and Commitment Therapy","Mobile Health (mHealth)","Mobile Application","Group Therapy","Digital Intervention",{"date":327,"type":42},{"date":70,"type":23},{"date":255,"type":23},{"name":48,"class":49},{"id":381,"slug":382,"hasResults":12,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":4,"eligibilityCriteria":386,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":290,"enrollmentInfo":387,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":389,"conditions":390,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":392,"startDateStruct":393,"completionDateStruct":394,"leadSponsor":395,"locationsCount":143},"100634612","balance--respiratory-muscle-strength-in-healthy-adults-100634612","NCT07541950","Balance & Respiratory Muscle Strength in Healthy Adults","Is There a Relationship Between Balance and Respiratory Muscle Strength in Healthy Individuals?","Inclusion Criteria:\n\n* Healthy individuals\n* Aged between 18-30 years\n* Voluntary participation\n\nExclusion Criteria:\n\n* Respiratory system disease\n* History of neurological disorders\n* Cardiovascular disease\n* Recent respiratory infection (last 3 months)",{"count":388,"type":23},32,"The study aims to examine the acute effects of balance exercises on balance performance in healthy individuals. It will be conducted with healthy males and females aged 18-25.\n\nThe research is an experimental study with a single-blind pre-test\u002Fpost-test design. Initially, participants' balance will be assessed using the Single Leg Stance Test. Then, a short balance exercise program lasting 8-10 minutes will be applied. Exercises include single-leg stance, eyes-closed balance, and unstable surface training. After the exercise, the same test will be repeated to evaluate changes. Perceived exertion will be measured using the Modified Borg Scale.\n\nThe collected data will be analyzed using SPSS software. The results are expected to contribute to improving balance, performance, and reducing injury risk.",[391],"Balance Disorders",{"date":348,"type":42},{"date":277,"type":23},{"date":304,"type":23},{"name":48,"class":49},{"id":397,"slug":398,"hasResults":12,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":402,"eligibilityCriteria":403,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":4,"enrollmentInfo":404,"targetDuration":265,"studyType":24,"phases":4,"briefSummary":406,"conditions":407,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":415,"lastUpdatePostDateStruct":416,"startDateStruct":417,"completionDateStruct":419,"leadSponsor":421,"locationsCount":4},"100617607","quality-of-life-and-functional-outcomes-in-laryngeal-cancer-patients-100617607","NCT07320820","Quality of Life and Functional Outcomes in Laryngeal Cancer Patients","Assessment of Quality of Life, Patient Satisfaction, Swallowing Function, Voice Outcomes, Pain, and Anxiety-Depression at Baseline and at 3-, 6-, and 12-Month Follow-Up in Patients Diagnosed With Laryngeal Squamous Cell Carcinoma: A Prospective Questionnaire-Based Study","QoL in LSSC","Inclusion Criteria:\n\n* Age ≥ 18 years at the time of enrollment.\n* Histopathologically confirmed diagnosis of laryngeal squamous cell carcinoma.\n* Planned to undergo surgical treatment or radiotherapy\u002Fchemoradiotherapy as part of standard oncological care.\n* Willing and able to participate in the study and to provide written informed consent.\n* No history of psychiatric or neurological disorders that could impair comprehension, questionnaire completion, or study participation.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years.\n* Presence of comorbid conditions that may independently affect swallowing or voice functions.\n* Patients who withdraw consent or request to discontinue participation during or after the treatment period.\n* History of psychiatric disorders or use of psychiatric medications that may interfere with study participation or completion of patient-reported outcome measures.",{"count":405,"type":23},120,"Laryngeal squamous cell carcinomas are head and neck malignancies that directly affect both swallowing and voice functions and are associated with a significant deterioration in patients' quality of life throughout the treatment process.\n\nThe aim of this study is to evaluate quality of life, voice and swallowing functions, pain, anxiety-depression levels, and patient satisfaction at the pre-treatment period and at the 3rd, 6th, and 12th months post-treatment in patients with laryngeal malignancies, using validated questionnaires, in order to:\n\nElucidate the course of functional recovery following treatment,\n\nIndividualize rehabilitation and follow-up strategies, and\n\nExamine the relationship between functional outcomes and oncological survival.",[408,409,410,411,412,413,414],"Laryngeal Carcinoma","Quality of Life (QOL)","Patient Satisfaction","Voice Quality","Swallowing Function","Pain Management","Anxiety Depression","2026-04-21",{"date":346,"type":42},{"date":418,"type":23},"2026-04-02",{"date":420,"type":23},"2027-12-31",{"name":48,"class":49},{"id":423,"slug":424,"hasResults":12,"nctId":425,"briefTitle":426,"officialTitle":427,"acronym":4,"eligibilityCriteria":428,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":4,"enrollmentInfo":429,"targetDuration":431,"studyType":24,"phases":4,"briefSummary":432,"conditions":433,"keywords":438,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":415,"lastUpdatePostDateStruct":444,"startDateStruct":445,"completionDateStruct":446,"leadSponsor":448,"locationsCount":4},"100616900","workplace-violence-and-safety-perception-among-ent-physicians-in-turkey-100616900","NCT07311629","Workplace Violence and Safety Perception Among ENT Physicians in Turkey","Perceived Safety and Security Against Workplace Violence Among Otolaryngology-Head and Neck Surgery Physicians: A Multicenter Cross-Sectional Survey Study in Turkey","Inclusion Criteria:\n\n* Licensed ENT-HNS specialist or resident physician\n* Aged 18 years or older\n* Willingness to participate and provide informed consent\n\nExclusion Criteria:\n\n* Physicians from other medical specialties\n* Surveys with more than 20% missing data",{"count":430,"type":23},450,"1 Day","This multicenter, cross-sectional survey study aims to evaluate the perceived level of safety and security against workplace violence among otolaryngology-head and neck surgery (ENT-HNS) physicians in Turkey. The study investigates the association between exposure to workplace violence and perceived safety, as well as the adequacy of institutional support mechanisms. Data will be collected through an anonymous online questionnaire distributed nationwide. The findings are expected to contribute to awareness and the development of preventive strategies and institutional safety policies for healthcare professionals.",[434,435,436,437],"Workplace Violence","Perceived Safety","Occupational Health","Otolaryngology-Head and Neck Surgery Physicians",[439,440,441,442,443],"Workplace violence","Safety perception","Otolaryngology","Healthcare professionals","Turkey",{"date":346,"type":42},{"date":418,"type":23},{"date":447,"type":23},"2026-09-01",{"name":48,"class":49},{"id":450,"slug":451,"hasResults":12,"nctId":452,"briefTitle":453,"officialTitle":454,"acronym":4,"eligibilityCriteria":455,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":339,"enrollmentInfo":456,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":457,"conditions":458,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":462,"completionDateStruct":463,"leadSponsor":464,"locationsCount":143},"100634504","smartphone-use-and-hand-function-in-young-adults-100634504","NCT07540546","Smartphone Use and Hand Function in Young Adults","The Relationship Between Daily Smartphone Use Duration and Dominant Hand Grip Strength, Thumb Strength, Wrist and Thumb Proprioception in Young Adults","Inclusion Criteria:\n\n* Healthy adults\n* Aged between 18 and 35 years\n* Voluntary participation in the study\n\nExclusion Criteria:\n\n* History of hand or wrist surgery\n* Fracture or serious injury in the hand\u002Fthumb within the last 6 months\n* Neurological disorders\n* Rheumatologic diseases\n* Cognitive impairment preventing understanding of instructions",{"count":58,"type":23},"This observational cross-sectional study aims to investigate the relationship between daily smartphone usage duration and hand function parameters in young adults. Specifically, the study will examine the association between smartphone screen time and dominant hand grip strength, thumb strength, and wrist and thumb proprioception. Healthy individuals aged 18-35 years will be included. All participants will undergo a single-session assessment including measurement of smartphone usage duration, hand grip strength, pinch strength, and joint position sense of the wrist and thumb. The findings are expected to provide insight into the potential effects of prolonged smartphone use on hand function and proprioceptive performance in young adults.",[459],"Smartphone Addiction","2026-04-18",{"date":346,"type":42},{"date":277,"type":23},{"date":304,"type":23},{"name":48,"class":49},{"id":466,"slug":467,"hasResults":12,"nctId":468,"briefTitle":469,"officialTitle":470,"acronym":4,"eligibilityCriteria":471,"healthyVolunteers":12,"sex":81,"minAge":360,"maxAge":4,"enrollmentInfo":472,"targetDuration":4,"studyType":59,"phases":474,"briefSummary":475,"conditions":476,"keywords":480,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":485,"lastUpdatePostDateStruct":486,"startDateStruct":488,"completionDateStruct":489,"leadSponsor":491,"locationsCount":4},"100635028","effect-of-animation-based-digital-education-on-risk-knowledge-and-frailty-in-older-adults-100635028","NCT07547358","EFFECT OF ANIMATION-BASED DIGITAL EDUCATION ON RISK KNOWLEDGE AND FRAILTY IN OLDER ADULTS","THE IMPACT OF A DIGITAL TRAINING MODEL DEVELOPED USING ANIMATION TECHNIQUE ON RISK KNOWLEDGE LEVEL AND FRAILTY AMONG OLDER ADULTS","Inclusion Criteria:\n\n* Aged 65 years or older\n* Ability to speak and understand Turkish\n* Minimum literacy level (able to read and write)\n* Mini-Mental State Examination (MMSE) score ≥ 24\n* No visual or auditory impairment, or ability to compensate for such impairments with assistive devices\n* Ability to interact with digital devices such as smartphones or tablets at a basic level\n\nExclusion Criteria:\n\n* Diagnosis of cognitive impairment or dementia\n\nWITHDRAWAL CRITERIA:\n\n* Participants will be withdrawn from the study if:\n* Serious health problems occur during any phase of the study or death occurs\n* Perception or compliance problems are identified during sessions\n* The participant fails to attend at least one educational session",{"count":473,"type":23},66,[61],"With the global aging trend, the management of geriatric risks faced by older adults and the effectiveness of health education for this population are gaining increasing importance. Literature indicates that health education for older adults, when delivered through methods that support individual engagement and the use of digital tools, yields more effective results in terms of learning and behavior change. This doctoral study aims to evaluate the effect of a digital education model, structured based on the Health Belief Model and developed using branching scenario animation technique, on geriatric risk knowledge level and frailty status among older adults residing in nursing homes.\n\nThe study will be conducted as a randomized controlled trial in three nursing homes in Istanbul, with measurements at baseline (T0), immediately post-intervention (T1), 1-month follow-up (T2), and 3-month follow-up (T3). Based on power analysis, 66 participants will be randomly assigned to intervention and control groups (33 per group) using block randomization. The intervention group will receive scenario-based digital animation education developed on the Vyond platform and structured according to the theoretical components of the Health Belief Model. The control group will receive standard care during the study period and will be offered the same digital animation education after completion of all assessments (post 3-month follow-up).\n\nThe primary outcome is geriatric risk knowledge level, assessed using an interactive digital game called \"Knowledge Wheel.\" Secondary outcomes include frailty status, measured by the Edmonton Frail Scale, and technology acceptance. Changes in knowledge and frailty levels measured through assessment tools will reveal the short- and medium-term effects of the education. Thus, the model's impact on health-related behavior change in older adults will be comprehensively evaluated.\n\nThe unique aspect of this study is that it will be one of the first experimental studies to implement an interactive scenario-based digital education model in older adults. The findings are expected to contribute to the development of age-friendly health education models.",[477,478,479],"Aging","Frail Elderly","Geriatric Syndromes",[481,482,483,484],"frailty","Older Adults","Digital Health Education","Branching Scenario Animation","2026-04-17",{"date":487,"type":42},"2026-04-23",{"date":447,"type":23},{"date":490,"type":23},"2027-02-01",{"name":48,"class":49},{"id":493,"slug":494,"hasResults":12,"nctId":495,"briefTitle":496,"officialTitle":497,"acronym":4,"eligibilityCriteria":498,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":4,"enrollmentInfo":499,"targetDuration":4,"studyType":59,"phases":501,"briefSummary":502,"conditions":503,"keywords":505,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":512,"lastUpdatePostDateStruct":513,"startDateStruct":514,"completionDateStruct":516,"leadSponsor":518,"locationsCount":143},"100635197","effect-of-manual-chest-wall-vibration-on-respiratory-function-and-chest-tube-duration-after-thoracic-surgery-100635197","NCT07549555","Effect of Manual Chest Wall Vibration on Respiratory Function and Chest Tube Duration After Thoracic Surgery","The Effect of Manual Chest Wall Vibration on Respiratory Functions and Chest Tube Duration in Patients Undergoing Thoracic Surgery","Inclusion Criteria:\n\n* Having undergone thoracic surgery\n* Having a chest tube in the postoperative period\n* Being hemodynamically stable\n* Agreeing to participate in the study\n* Being open to communication and cooperation\n\nExclusion Criteria:\n\n* Severe cardiac instability\n* Patients unable to tolerate the procedure due to neurological or cognitive impairment\n* Clinical conditions that would prevent the application of vibration to the chest wall\n* Patients diagnosed with pneumonia\n* Patients with a newly implanted transvenous or subcutaneous pacemaker",{"count":500,"type":23},60,[61],"This study was conducted to determine the effects of a manual vibration technique applied to the chest wall on the duration of chest tube placement, secretion clearance, and hemodynamic parameters in patients with chest tubes.",[504],"Thoracic Diseases",[506,507,508,509,510,511],"Thoracic surgery","Chest tubes","Chest wall oscillation","Physical therapy modalities","Postoperative care","Airway Clearance Techniques","2026-04-16",{"date":275,"type":42},{"date":515,"type":42},"2025-10-01",{"date":517,"type":23},"2026-05",{"name":48,"class":49},{"id":520,"slug":521,"hasResults":12,"nctId":522,"briefTitle":523,"officialTitle":524,"acronym":4,"eligibilityCriteria":525,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":360,"enrollmentInfo":526,"targetDuration":4,"studyType":59,"phases":528,"briefSummary":529,"conditions":530,"keywords":532,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":539,"startDateStruct":541,"completionDateStruct":542,"leadSponsor":544,"locationsCount":143},"100634354","medication-training-via-ignite-based-on-roy-model-in-heart-failure-medication-adherence-and-symptom-management-100634354","NCT07538596","Medication Training Via Ignite Based on Roy Model in Heart Failure: Medication Adherence and Symptom Management","The Effect of Medication Management Training Delivered Via the Digital Presentation Format Ignite, Based on the Roy Adaptation Model, on Medication Adherence and Symptom Management in Individuals Diagnosed With Heart Failure","Inclusion Criteria:\n\n* Must be 18 years of age or older.\n* Individuals who are willing to participate in the study\n* No communication problems\n* Having been diagnosed with KY for at least 6 months\n* Having the ability to read, write and speak Turkish .\n* Mildly reduced ejection fraction (left ventricular EF 41-49%)\n* Individuals with WhatsApp application\n* Individuals who can use a smartphone\n\nExclusion Criteria:\n\n* Not being willing to participate in the study don't be under the age of 18\n* Lack of ability to read, write and speak Turkish\n* Low ejection fraction (left ventricle EF. 40%)\n* Preserved ejection fraction (left ventricular EF.50%)",{"count":527,"type":23},70,[61],"The goal of this clinical trial is to learn if a structured medication training program can help people with heart failure better manage their condition. The program is based on the Roy Adaptation Model and is designed to support how people adjust to their illness.\n\nThe main questions it aims to answer are:\n\nDoes the training program improve heart failure symptoms? Does the training program help participants take their medications as prescribed?\n\nResearchers will compare a training program group to a control group receiving standard care to see if the program is effective.\n\nParticipants will:\n\nBe randomly assigned to either a training program group or a control group Receive the training program through WhatsApp after hospital discharge or receive standard discharge education Be followed for 12 weeks Complete questionnaires at the start of the study, at 4 weeks, and at 12 weeks",[531],"Hearth Failure With Reduced Ejection Fraction (HFrEF)",[533,534,535,536,537],"hearth failure","roy adaptation","nurse care","digital presentation","education","2026-04-15",{"date":540,"type":42},"2026-04-20",{"date":538,"type":23},{"date":543,"type":23},"2026-11-25",{"name":48,"class":49},{"id":546,"slug":547,"hasResults":12,"nctId":548,"briefTitle":549,"officialTitle":549,"acronym":4,"eligibilityCriteria":550,"healthyVolunteers":17,"sex":81,"minAge":19,"maxAge":207,"enrollmentInfo":551,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":552,"conditions":553,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":557,"lastUpdatePostDateStruct":558,"startDateStruct":559,"completionDateStruct":560,"leadSponsor":561,"locationsCount":4},"100634505","the-effect-of-coffee-consumption-on-balance-100634505","NCT07540559","The Effect of Coffee Consumption on Balance","Inclusion Criteria:\n\n* Healthy adult\n* Between 18-25 years of age\n* University students\n* Body Mass Index (BMI) \\\u003C 25 kg\u002Fm²\n* Voluntary participation in the study\n\nExclusion Criteria:\n\n* Smoking\n* Presence of any systemic, orthopedic, or cardiopulmonary condition that may prevent participation in exercise tests\n* Diagnosed respiratory, vascular, or cardiovascular disease",{"count":388,"type":23},"This study aims to investigate the effects of daily coffee consumption on balance performance in healthy university students. Caffeine is a widely consumed psychoactive substance that may influence neuromuscular control, reaction time, and postural stability. Participants will be categorized based on their habitual caffeine intake levels, and balance performance will be assessed using standardized clinical tests. The results are expected to contribute to the understanding of the relationship between caffeine consumption and balance performance.",[554,555,556],"Balanced","Postural; Defect","Coffee Consumption","2026-04-13",{"date":540,"type":42},{"date":277,"type":23},{"date":304,"type":23},{"name":48,"class":49},{"id":563,"slug":564,"hasResults":12,"nctId":565,"briefTitle":566,"officialTitle":566,"acronym":4,"eligibilityCriteria":567,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":568,"enrollmentInfo":569,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":571,"conditions":572,"keywords":4,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":557,"lastUpdatePostDateStruct":574,"startDateStruct":575,"completionDateStruct":576,"leadSponsor":578,"locationsCount":143},"100619440","turkish-validation-of-the-nijmegen-questionnaire-in-copd-100619440","NCT07344649","Turkish Validation of the Nijmegen Questionnaire in COPD","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Diagnosis of COPD confirmed according to GOLD criteria\n* Clinically stable disease (no acute exacerbation or hospitalization within the last 4 weeks)\n* Ability to read and understand Turkish\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Acute COPD exacerbation or respiratory infection within the previous 4 weeks\n* Presence of severe cardiac, neurological, or systemic disease affecting questionnaire responses\n* Coexisting pulmonary conditions such as bronchiectasis, lung cancer, prior pulmonary tuberculosis, pleural disease, or history of lung surgery\n* Moderate to severe cognitive impairment or communication difficulties\n* Severe visual or hearing impairment preventing questionnaire completion\n* Pregnancy\n* Refusal to participate or withdrawal during the study","75 Years",{"count":570,"type":23},90,"Dysfunctional breathing is a common and clinically relevant problem in patients with chronic obstructive pulmonary disease (COPD), contributing to increased dyspnea perception, reduced exercise tolerance, and impaired quality of life. The Nijmegen Questionnaire (NQ) is a widely used symptom-based instrument for screening dysfunctional breathing; however, a validated Turkish version for patients with COPD is currently unavailable.\n\nThis observational methodological study aims to translate, culturally adapt, and evaluate the validity and reliability of the Turkish version of the Nijmegen Questionnaire (NQ-TR) in individuals with stable COPD.",[573],"COPD",{"date":538,"type":42},{"date":557,"type":42},{"date":577,"type":23},"2027-01-01",{"name":48,"class":49},{"id":580,"slug":581,"hasResults":12,"nctId":582,"briefTitle":583,"officialTitle":583,"acronym":4,"eligibilityCriteria":584,"healthyVolunteers":17,"sex":81,"minAge":20,"maxAge":585,"enrollmentInfo":586,"targetDuration":4,"studyType":59,"phases":587,"briefSummary":588,"conditions":589,"keywords":591,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":557,"lastUpdatePostDateStruct":595,"startDateStruct":596,"completionDateStruct":598,"leadSponsor":600,"locationsCount":143},"100614903","brain-and-peripheral-muscle-oxygenation-in-patients-with-chronic-obstructive-pulmonary-disease-100614903","NCT07285642","Brain and Peripheral Muscle Oxygenation in Patients With Chronic Obstructive Pulmonary Disease","Inclusion Criteria\n\n* Age 40-70 years\n* Diagnosis of moderate-to-severe COPD (GOLD stage II-III)\n* Stable disease (no exacerbation in previous 4 weeks)\n* BMI 18.5-24.9 kg\u002Fm²\n* Manual muscle strength ≥ 4 (MRC scale)\n* Ability to perform exercise tests safely\n* Written informed consent\n\nExclusion Criteria\n\n* Severe comorbid conditions (uncontrolled cardiac, neurological, or orthopedic disease)\n* Need for high-flow oxygen therapy (\\>2 L\u002Fmin)\n* History of cerebrovascular disease or transient ischemic attack\n* Musculoskeletal or dermatological conditions impairing NIRS measurement sites\n* Restrictive lung disease, interstitial lung disease, or small-airway disease\n* Participation in an exercise program within the last 12 months\n\nHealthy Controls\n\n* Age 40-70 years\n* No acute or chronic disease\n* Non-smoker\n* BMI 18.5-24.9 kg\u002Fm²\n* No musculoskeletal limitations","70 Years",{"count":500,"type":23},[61],"This interventional study aims to investigate the acute effects of different types of exercise on cerebral and peripheral muscle oxygenation in patients with chronic obstructive pulmonary disease (COPD). Functional near-infrared spectroscopy (fNIRS) and near-infrared spectroscopy (NIRS) will be used simultaneously to measure oxygenation changes in the prefrontal cortex and the vastus lateralis muscle during rest, Stroop task performance, the six-minute walk test, aerobic, strengthening, and breathing exercises.\n\nThe study will compare COPD patients and age- and sex-matched healthy controls to determine how brain and muscle oxygenation responses differ between groups and among exercise modalities. The findings are expected to guide the design of safe, individualized pulmonary rehabilitation programs that optimize oxygenation without compromising safety.",[590],"Copd",[573,592,593,594],"FNIRS","Brain","Quadriceps femoris",{"date":538,"type":42},{"date":597,"type":42},"2025-04-30",{"date":599,"type":23},"2026-11-01",{"name":48,"class":49},{"id":602,"slug":603,"hasResults":12,"nctId":604,"briefTitle":605,"officialTitle":606,"acronym":4,"eligibilityCriteria":607,"healthyVolunteers":12,"sex":81,"minAge":19,"maxAge":608,"enrollmentInfo":609,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":611,"conditions":612,"keywords":4,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":557,"lastUpdatePostDateStruct":614,"startDateStruct":615,"completionDateStruct":617,"leadSponsor":619,"locationsCount":143},"100595439","social-media-addiction-and-compulsive-exercise-behaviors-100595439","NCT07032467","Social Media Addiction and Compulsive Exercise Behaviors","Examining the Relationship Between Social Media Addiction and Compulsive Exercise Behaviors in University Students","Inclusion Criteria:\n\n* Healthy adult\n* Between 18-24 years of age\n* Spending at least 4 hours a day on social media\n* Voluntarily participating in the study\n\nExclusion Criteria:\n\n* Participants must be under 18 and over 24 years of age,\n* Surf social media for less than 4 hours a day,\n* Have a diagnosed psychiatric disorder","24 Years",{"count":610,"type":23},187,"This cross-sectional study investigates the association between social media addiction levels and compulsive exercise behaviors among university students aged 18-24. Using validated self-report instruments, the study explores how increasing digital media engagement relates to exercise patterns and dependency traits, offering insights into the psychological-behavioral dynamics of young adults in the digital age.",[613],"Healthy",{"date":538,"type":42},{"date":616,"type":42},"2025-08-26",{"date":618,"type":23},"2026-06-20",{"name":48,"class":49},""]