[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Saint Luke's Health System\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":86},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,62],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100469076","effect-of-a-quality-improvement-initiative-to-address-social-determinants-of-health-on-rehospitalization-rates-in-patients-with-heart-failure-100469076",false,"NCT05388097","Effect of a Quality Improvement Initiative to Address Social Determinants of Health on Rehospitalization Rates in Patients With Heart Failure","A Novel Strategy for Addressing Social Barriers to a Successful, Sustained Discharge From the Hospital for Acute Heart Failure","Inclusion Criteria:\n\n* Aged 18-99 years\n* Resident of Missouri or Kansas\n* Current inpatient admission for acute heart failure\n\nExclusion Criteria:\n\n* Under 18 years or over 99 years of age","ALL","18 Years","99 Years",{"count":20,"type":21},320,"ESTIMATED","INTERVENTIONAL",[24],"NA","The objective of this program is to improve post-acute care coordination for necessary social services for patients leaving the hospital after recovering from an episode of decompensated heart failure.",[27],"Heart Failure",[29],"heart failure","RECRUITING","2024-06-13",{"date":33,"type":34},"2024-06-14","ACTUAL",{"date":36,"type":34},"2021-05-03",{"date":38,"type":21},"2026-06",{"name":40,"class":41},"Saint Luke's Health System","OTHER",{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":55,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},"100446463","quantification-of-debris-captured-using-tcep-during-viv-tavr-with-bvf-100446463","NCT05093764","Quantification of Debris Captured Using TCEP During VIV TAVR With BVF","Quantification of Debris Captured Using Transcatheter Cerebral Embolic Protection (TCEP) During Valve in Valve Transcatheter Aortic Valve Replacement (VIV TAVR) With Bioprosthetic Valvular Fracture (BVF)","Inclusion Criteria:\n\n* Men and Women ≥ 18 years of age\n* The patient has severe bioprosthetic aortic valve degeneration (stenosis, insufficiency, or mixed valve disease) and a clinical indication for VIV TAVR\n* The bioprosthetic valve can be fractured with high pressure balloon inflation.\n* The patient is deemed at prohibitive or high mortality risk related to surgical aortic valve replacement as assessed by the Heart Team\n* For procedural planning, all patients must have a CT angiogram of the chest, abdomen and pelvis to confirm:\n\nA. Adequate femoral access for the TAVR procedure B. Appropriate right subclavian, carotid and brachiocephalic as well as left carotid artery anatomy for the SENTINEL device deployment.\n\n* The patient or legal representative is able to understand and willing to provide written informed consent to participate in the trial\n* The patient is able and willing to return for required follow-up visits and examinations\n* The patient is evaluated by the multidisciplinary heart-valve team and found to be a suitable for the procedure.\n\nExclusion Criteria:\n\n* Patients with low or moderate mortality risk from surgical aortic valve replacement\n* Patients with bioprosthetic valves that cannot be fractured with standard non-compliant valvuloplasty balloons (Table 1)\n* Patients with evidence of significant carotid artery stenosis (i.e., carotid stenosis ≥ 50%), noted on ultrasound duplex imaging or CT angiography.\n* Patients with evidence of right subclavian\u002Fbrachiocephalic artery stenosis\n* Patients with right arm\u002Fforearm dialysis fistula or graft.\n* Patients with harvested right radial artery for a previous coronary bypass surgery.\n* Patients with prohibitive aortic arch anomalies for SENTINEL device implantation.\n* The patient with history of cerebrovascular event (CVA) within within 6 months.\n* Patient with incidental left atrial appendage thrombus noted on TEE or CT imaging.\n* The patient is actively enrolled in another trial of a cardiovascular device or an investigational drug (post-market study participation and registries are acceptable)\n* The patient is pregnant, or pregnancy is planned during the course of the investigation if patient is of child-bearing potential\n* Any clinically significant medical condition or presence of any laboratory abnormality performed prior to randomization that is considered by the investigator to be clinically important and could interfere with the conduct of the study or not meeting procedure guidelines for TAVR or SENTINEL\n* The patient has a life expectancy of less than one year",{"count":50,"type":21},20,[24],"The objective of this study is to quantify the amount of debris captured by the SENTINEL transcatheter cerebral embolic protection (TCEP) device in patients undergoing valve in valve transcatheter aortic valve replacement (VIV TAVR) with bioprosthetic valvular fracture (BVF)",[54],"Aortic Valve Disease",{"date":33,"type":34},{"date":57,"type":34},"2022-03-02",{"date":59,"type":21},"2025-12-31",{"name":40,"class":41},1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":66,"acronym":67,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":22,"phases":72,"briefSummary":73,"conditions":74,"keywords":4,"overallStatus":76,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},"100508433","feasibility-and-success-trial-of-remote-patient-monitoring-in-heart-failure-100508433","NCT05900362","Feasibility and Success Trial of Remote Patient Monitoring in Heart Failure","FAST-RPM-HF","Inclusion Criteria:\n\n* A clinical diagnosis of heart failure\n* New York Heart Association Class II or III congestive HF symptoms\n* Admission to hospital within 12 months for symptomatic heart failure.\n* Own a smartphone or tablet or comfortable with using one\n* English as primary language\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Left Ventricular Ejection Fraction \\\u003C 35%\n* Implanted cardiac device (permanent pacemaker (PPM), implantable cardioverter defibrillator (ICD), chronic resynchronization therapy (CRT), implantable loop recorder (ILR))\n* CardioMEMS\n* Left ventricular assist device (LVAD)\n* NYHA Class I or IV congestive HF symptoms\n* Listed for cardiac transplant\n* Pregnant at time enrollment\n* End-stage renal disease","80 Years",{"count":71,"type":21},30,[24],"Previous research has investigated the use of remote patient monitoring in various clinical contexts, however there has not been a clinical trial examining use of the VitalCare platform for ambulatory management of heart failure. This trial will serve as a pilot study examining the feasibility of use of the VitalCare platform for ambulatory heart failure management and examine the effect of remote patient monitoring on patient engagement. To the investigators' knowledge, this will be the first study examining the effect of remote patient monitoring with the VitalCare platform on heart failure clinical outcomes, such as hospitalization for heart failure exacerbations and emergency room visits for heart failure.",[75],"Congestive Heart Failure","NOT_YET_RECRUITING","2024-06-05",{"date":79,"type":34},"2024-06-06",{"date":81,"type":21},"2024-08-01",{"date":83,"type":21},"2026-04-30",{"name":40,"class":41},4,""]