[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sakarya Applied Sciences University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":80},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100600090","comparison-of-the-effects-of-aerobic-anaerobic-exercises-on-hormonal-and-immune-biomarkers-100600090",false,"NCT07092969","Comparison of the Effects of Aerobic-Anaerobic Exercises on Hormonal and Immune Biomarkers","Comparison of the Effects of Aerobic and Anaerobic Exercises on Hormonal and Immune Biomarkers Measured by Blood and Saliva in Young Individuals","Biomarkers","Inclusion Criteria:\n\n* Being a university student,\n* Being between the ages of 18 and 25.\n\nExclusion Criteria:\n\n* Having orthopedic problems that prevent exercise,\n* Having cognitive or mental health problems that prevent participation in exercise,\n* Having chronic systemic diseases such as cardiac, pulmonary, or nephrological.",true,"ALL","18 Years","25 Years",{"count":22,"type":23},90,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study aims to compare the effects of aerobic and anaerobic exercise on hormonal, immunological, and metabolic biomarkers in young individuals using blood and saliva samples. It will also assess participants' physical activity levels, depression levels, and general lifestyle habits to explore their relationship with biomarker profiles. Biomarkers such as testosterone, progesterone, cortisol, IgA, alpha-amylase, insulin, lactate, and various inflammatory cytokines will be measured using ELISA. The study seeks to evaluate the physiological and psychosocial effects of different types of exercise in a holistic manner.",[29,15,30,31],"Activity, Motor","Exercise","Immunity",[33,34,35,36],"Exercise physiology","Aerobic and anaerobic exercis","Hormonal and immunological responses","Physical activity","NOT_YET_RECRUITING","2025-07-28",{"date":40,"type":41},"2025-07-30","ACTUAL",{"date":43,"type":23},"2025-09-15",{"date":45,"type":23},"2026-09-15",{"name":47,"class":48},"Sakarya Applied Sciences University","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":57,"minAge":19,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":24,"phases":61,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100598963","effect-of-respiratory-exercises-with-pelvic-floor-rehab-on-dyspareunia--autonomic-function-in-women-100598963","NCT07078318","Effect of Respiratory Exercises With Pelvic Floor Rehab on Dyspareunia & Autonomic Function in Women","The Effect of Respiratory Exercises Given in Addition to Pelvic Floor Rehabilitation on Dyspareunia and Autonomic Nervous System in Women With Musculoskeletal Dyspareunia","Dyspareunia","Inclusion Criteria:\n\nFemale participants aged between 18 and 45 years\n\nExperiencing dyspareunia of musculoskeletal origin for at least 6 months\n\nIn a stable sexual relationship and sexually active\n\nWilling and able to attend weekly treatment sessions for 8 weeks\n\nAble to provide informed consent\n\nNo pelvic surgery within the last 6 months\n\nNormal cognitive function and ability to follow instructions\n\nBaseline FSFI score indicating sexual dysfunction (e.g., ≤ 26.55)\n\nExclusion Criteria:\n\n* Presence of neurological, gynecological, or urological pathologies causing pelvic pain (e.g., endometriosis, pelvic inflammatory disease)\n\nPregnancy or postpartum period within the last 6 months\n\nDiagnosed psychiatric disorders (e.g., major depression, psychosis)\n\nUse of medications that affect autonomic nervous system function (e.g., beta-blockers, antidepressants)\n\nHistory of pelvic radiation, cancer, or pelvic trauma\n\nParticipation in other rehabilitation or psychotherapy programs during the study period\n\nInability to tolerate manual therapy or perform breathing exercises\n\nBMI \\> 35, which may interfere with ultrasonographic assessment\n\nNon-compliance risk, such as irregular attendance or language barriers","FEMALE","45 Years",{"count":60,"type":23},45,[26],"Background and Aim:\n\nDyspareunia, or pain during sexual intercourse, is a common component of female sexual dysfunction and may have multifactorial origins, including musculoskeletal and autonomic factors. While pelvic floor rehabilitation is an established treatment approach for musculoskeletal dyspareunia, it may not sufficiently address the autonomic dysregulation commonly observed in chronic pain conditions. The aim of this study is to investigate the effects of adding diaphragmatic breathing exercises and diaphragm manual therapy to standard pelvic floor rehabilitation on pain severity, pelvic floor function, and autonomic nervous system regulation in women diagnosed with musculoskeletal-origin dyspareunia.\n\nMethods:\n\nThis randomized controlled clinical trial will be conducted between September 1, 2025, and December 1, 2025, at the Kurbaa Training and Consultation Center in Istanbul. A total of 45 participants aged 18-45 years who meet the inclusion criteria will be randomly assigned into three equal groups (n = 15):\n\nGroup I: Pelvic floor rehabilitation only\n\nGroup II: Pelvic floor rehabilitation + diaphragmatic breathing exercises\n\nGroup III: Pelvic floor rehabilitation + diaphragmatic breathing exercises + diaphragm manual therapy\n\nInterventions will be administered once per week for 8 weeks. Pre- and post-intervention assessments will include pain intensity (Visual Analog Scale), pelvic floor muscle function (ultrasonography), sexual function (Female Sexual Function Index), anxiety level (Beck Anxiety Inventory), and autonomic regulation (Heart Rate Variability using Elite HRV). Statistical analyses will be performed using SPSS with significance set at p \\\u003C 0.05.\n\nExpected Contribution:\n\nThis study is expected to contribute to the development of more comprehensive treatment protocols for dyspareunia by integrating physical and neurophysiological rehabilitation components. It may also provide evidence supporting the role of autonomic regulation in improving treatment outcomes for female sexual pain disorders.",[64,65,66],"Dyspareunia (Female Excluding Psychogenic)","Female Sexual Dysfunction (FSD)","Chronic Pelvic Pain",[55,68,69,70,71],"Pelvic Floor Rehab","Manual Therapy","Autonomic Regulation","Sexual Dysfunction","2025-07-13",{"date":74,"type":41},"2025-07-22",{"date":76,"type":23},"2025-09-01",{"date":78,"type":23},"2026-12-01",{"name":47,"class":48},""]