[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sardar Umer Rehman\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100625962","phase-1-comparison-of-clinical-outcomes-of-intraperitoneal-bupivacaine-instillation-versus-placebo-as-preemptive-analgesia-in-patients-undergoing-open-appendectomy-100625962",false,"NCT07429448","Comparison Of Clinical Outcomes of Intraperitoneal Bupivacaine Instillation Versus Placebo as Preemptive Analgesia in Patients Undergoing Open Appendectomy","Inclusion Criteria:\n\n* Patients presenting to the emergency department undergoing open appendectomy.\n\nExclusion Criteria:\n\n* Patients undergoing interval appendectomy or having perforated appendix as evident by examination (abdominal tenderness\u002F fever) and USG findings (presence of abscess, fluid collection, or free air).\n* Uncontrolled medical disease (DM: BSL \\>200mg\u002Fdl, HTN: BP \\>140\u002F90)\n* History of chronic kidney or liver disease\u002F psychiatric illness\u002F Active peptic ulcer disease (as determined on history and medical records)\n* Alcoholics\n* History of chronic pain or patients on analgesic medications\n* Pregnant females\n* History of allergy to bupivacaine\u002F ketorolac as determined on history\n* Children, Adolescents and patients with mental illness.","ALL","20 Years","60 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"PHASE1","To compare the clinical outcomes of intraperitoneal bupivacaine instillation vs placebo as preemptive analgesia in patients undergoing open appendectomy",[26],"Appendectomy",[28,29,30],"Analgesia","Bupivacaine","Open Appendectomy","RECRUITING","2026-02-17",{"date":34,"type":35},"2026-02-24","ACTUAL",{"date":37,"type":35},"2025-12-16",{"date":39,"type":20},"2026-06-16",{"name":41,"class":42},"Sardar Umer Rehman","OTHER_GOV",""]