[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Schulthess Klinik\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":168},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,41,64,96,123,143],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100608133","validity-and-reliability-of-calf-raise-tests-in-patients-with-achilles-tendon-rupture-and-lateral-ankle-sprain-100608133",false,"NCT07197593","Validity and Reliability of Calf Raise Tests in Patients With Achilles Tendon Rupture and Lateral Ankle Sprain","General Inclusion Criteria:\n\n* Signed informed consent\n* Aged 18-65 years\n* German or English speaking\n\nInclusion Criteria:\n\nLAS individuals: Unilateral LAS 4-16 weeks post-injury diagnosed by a physician as LAS, supination trauma, ankle distortion or ligamentous ankle injury.\n\nATR individuals: Unilateral ATR 6- 24 months post-injury\u002Fsurgery (surgical or conservative treatment).\n\nHealthy controls: Matched to Patients by Group Level: Physical Activity, Age and Gender.\n\nExclusion Criteria:\n\nLAS individuals: Medial Ligament injuries (Grade II or III) ATR individuals: Previous ATR\n\nGeneral Exclusion Criteria:\n\n* Chronic Ankle Instability (defined by symptoms such as giving way, perceived instability and at least one LAS within the last 6 months)\n* Previous ATR\n* Other lower limb injury and\u002For surgery in the last year (e.g. fractures, ligament reconstructions or other conditions resulting in ≥ 6 months of sports inactivity)\n* Impaired motor function of the lower limb due to neurovascular or neurological diseases\n* Vestibular or visual disturbances\n* Or any other pathoanatomic abnormality that would affect motor performance (e.g. foot arthrodesis, toe amputation\u002Fmissing toes or other conditions such as joint deformities, severe chronic pain).",true,"ALL","18 Years","65 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to evaluate the validity and reliability of clinically used Calf Raise Test parameters (collected with the \"the Calf Raise App\") between patients with Lateral Ankle Sprain or Achilles Tendon Repair and healthy controls.",[27,28],"Achilles Tendon","Ankle Sprain","NOT_YET_RECRUITING","2025-09-22",{"date":32,"type":33},"2025-09-29","ACTUAL",{"date":35,"type":21},"2025-10-01",{"date":37,"type":21},"2026-05-31",{"name":39,"class":40},"Schulthess Klinik","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":22,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":4},"100604993","effect-of-contralateral-nmes-on-quadriceps-activation-after-acl-injury-or-surgery-100604993","NCT07156734","Effect of Contralateral NMES on Quadriceps Activation After ACL Injury or Surgery","Does NMES Applied to the Contralateral Uninjured Side Facilitate Voluntary Quadriceps Activation Before and After ACL Surgery?","ACLQuadAct","Inclusion Criteria:\n\n* Patients undergoing ACL surgery with semitendinosus tendon autograft in the Schulthess Clinic\n* Unilateral and primary ACL injury (with\u002Fwithout diagnoses of additional meniscus injury)\n\nExclusion Criteria:\n\n* Previous surgery\u002Fligament rupture in injured or uninjured knee or hip\n* Severe pain in the uninjured-side quadriceps or knee joint\n* Ongoing pregnancy\n* BMI \\>30 kg\u002Fm²\n* Neuromuscular disease\n* Open wounds or tissue injuries on the anterior aspect of the thigh\n* Additional rupture of other knee ligaments (posterior cruciate ligament, medial collateral ligament, lateral collateral ligament)\n* Implanted metallic\u002Felectronic devices (cardiac pacemakers, defibrillators)\n* Patients getting a femoralis block (peripheral nerve block) after surgery will be excluded for the post-surgical appointment\n* Insufficient language comprehension","50 Years",{"count":51,"type":21},25,[24],"A major complication after cruciate ligament injury and surgery is arthrogenic muscle inhibition of the quadriceps, which is characterised by a deficit in voluntary muscle activation in the affected leg. This can hinder rehabilitation processes, lead to impaired knee function, and negatively impact the patients' quality of life. The primary objective of this study is to assess whether voluntary quadriceps activation on the injured side is facilitated by the concomitant application of neuromuscular electrical stimulation (NMES) on the contralateral quadriceps.",[55],"ACL Injury","2025-08-27",{"date":58,"type":33},"2025-09-05",{"date":60,"type":21},"2025-09",{"date":62,"type":21},"2026-09",{"name":39,"class":40},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":70,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":16,"minAge":72,"maxAge":4,"enrollmentInfo":73,"targetDuration":4,"studyType":75,"phases":4,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},"100563183","validation-of-the-single-item-sleep-quality-scale-100563183","NCT06612853","Validation of the Single-item Sleep Quality Scale","Cross-cultural Adaptation Into German and Italian, Validation, Reproducibility, and Responsiveness of the Single-item Sleep Quality Scale in Spine Patients","SQS","Inclusion Criteria:\n\n* both male and female patients\n* German-speaking or Italian-speaking\n* diagnosis of spine pathology\n* age ≥ 14 years\n* cognitively intact (self-reported)\n\nExclusion Criteria:\n\n* pregnancy (self-reported)\n* medical and\u002For pharmacological treatment for sleep disorders\n* melatonin intake\n* daily use of smart-watch or applications for automatic sleep detection\n* inability to give informed consent","14 Years",{"count":74,"type":21},240,"OBSERVATIONAL","The single-item sleep quality scale (SQS) allows patients to provide a self-assessment of sleep quality over a 7-day recall period without significant additional burden. However, the SQS has not yet been utilized or validated in patients with spine pathologies. The main purpose of this study is to cross-culturally adapt the SQS from English to German and Italian and to test its validity in patients with back disorders. The study will be conducted in two stages. The first stage will involve the translation and cross-cultural adaptation of the SQS from English to German and Italian. The second stage will involve the evaluation of the instrument's face, content, and construct validity, reproducibility, and responsiveness in patients with back disorders.",[78],"Spine Disorder",[80,81,82,83,84,70,85],"Cross cultural adaptation","Translation","Validity","Reproducebility","Responsiveness","Sleep quality","RECRUITING","2024-11-26",{"date":89,"type":33},"2024-11-29",{"date":91,"type":33},"2024-10-01",{"date":93,"type":21},"2025-12-31",{"name":39,"class":40},1,{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":110,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":117,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":95},"100533278","spine-deformity-patients-with-optoelectronic-motion-capture-100533278","NCT06223737","Spine Deformity Patients With Optoelectronic Motion Capture","Characterization of Patients Suffering From Adult Spine Deformities With Optoelectronic Motion Analysis","Inclusion Criteria:\n\n* both male and female subjects\n* BMI \\\u003C 30 kg\u002Fm2\n* cognitively intact\n* degenerative spinal deformity presenting with at least one criterion:\n\n  * Coronal Cobb angle ≥20°\n  * sagittal vertical axis (SVA) ≥5 cm\n  * thoracic kyphosis (TK) ≥60°\n  * pelvic tilt (PT) ≥25°.\n\nExclusion Criteria:\n\n* age under 18 years or over 75 years\n* any prior spinal surgery or other musculoskeletal surgery having an impact on movement\n* pregnancy\n* inability to perform the planned set of daily activities\n* inability to give consent.","75 Years",{"count":105,"type":21},30,[24],"Aging-induced changes in the spine can lead to adult spinal deformity, causing a forward and\u002For lateral shift of the trunk. While mild cases may have compensatory mechanisms, severe deformities necessitate treatment. Surgery with instrumentation effectively corrects deformities, but complications are common. Precise pre-operative planning based on X-rays is essential. However, radiological imaging has limitations, including ionizing radiation exposure and static nature. Marker-based optoelectronic motion analysis systems offer potential benefits for dynamic spine assessment.\n\nThis study aims to test the feasibility of using motion analysis systems to characterize spinal alignment and balance in patients with adult spine deformity. The primary objective is to assess the practical implementation, measurement capability, and resources required for motion analysis. Secondary objectives include investigating errors in absolute spinal curvature assessment and developing compensation strategies.\n\nThe project will recruit 20 patients (non-operated and operated) seeking medical attention for adult spine deformities and 10 healthy controls. Participants will undergo biplanar imaging and motion analysis to capture static and dynamic spine alignment during common activities. The data will help build patient-specific musculoskeletal models, offering potential insights into improving surgical planning for adult spine deformities.",[109],"Spine Deformity",[111,112,113,114,115,116],"Adult Spine Deformity","Surgical Planning","Spinal Deformity","Optoelectronic Motion Analysis","Biplanar Radiography","Absolute Spinal Curvature",{"date":89,"type":33},{"date":119,"type":21},"2025-05-01",{"date":121,"type":21},"2026-12-30",{"name":39,"class":40},{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":4,"eligibilityCriteria":129,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":4,"targetDuration":4,"studyType":130,"phases":4,"briefSummary":131,"conditions":132,"keywords":134,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":4,"completionDateStruct":4,"leadSponsor":142,"locationsCount":95},"100355250","robot-assisted-physical-therapy-for-pseudoparalysis-in-massive-rotator-cuff-tear-100355250","NCT03905499","Robot Assisted Physical Therapy for Pseudoparalysis in Massive Rotator Cuff Tear","Can Robot Assited Physical Therapy Affect Pseudoparalysis in Patients Treated for Massive Rotator Cuff Tear? A Feasibility Study","Inclusion Criteria:\n\n* Active flexion \\\u003C45°\n* Massive, irreparable, atraumatic RC tear at least two tendons\n* Almost full passive ROM glenohumeral (140-180°)\n* Fatty infiltration of the muscle Goutallier grade III or IV\n* Persistent loss of active ROM after injection\n* Ability to speak and understand German or English\n\nExclusion Criteria:\n\n* Neurological disease\n* Clinical diagnosis of rheumatoid arthritis, glenohumeral osteoarthritis, periarthritis and necrosis\n* RC repair in the previous two years\n* Acute fracture\n* Acute traumatic RC tear\n* Capsular shoulder stiffness","EXPANDED_ACCESS","The primary objective of this study is to assess the efficacy of a robot assisted therapy in a clinical setting and its potential benefit for patients with rotator cuff tear associated with pseudoparalysis. eighty patients with clinical signs of pseudoparalysis will be recruited through doctors and physical therapists based on eligibility criteria. After completing the baseline assessments, patients will be randomized into the robot-assisted physical therapy intervention or control comparison group. Enrolled patients will conduct a specific trainings program with the MJS Tecnobody (Multi Joint System 614P Tecnobody Srl, IT) three times a week over a period of six weeks. Feasibility assessment will be performed six and twelve weeks after baseline and secondary outcomes (Oxford shoulder score, subjective shoulder value, pain level during activity of daily living, active shoulder flexion and abduction and quality of life EQ-5D-5L) will be assessed at baseline, six and twelve weeks post intervention.",[133],"Pseudoparalysis Due to Massive Rotator Cuff Tear",[135,136,137],"Massive rotator cuff tear","Pseudoparalysis","Robotic mediated therapy","AVAILABLE","2024-06-06",{"date":141,"type":33},"2024-06-07",{"name":39,"class":40},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":4,"eligibilityCriteria":149,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":49,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":95},"100512484","tunnel-widening-in-augmented-acl-integration-via-prp-enriched-collected-autologous-bone-vs-standard-acl-technique-100512484","NCT05953051","Tunnel Widening in Augmented ACL Integration Via PrP Enriched Collected Autologous Bone vs Standard ACL Technique","A Single-center, Patient-blinded, Randomized, 2-year, Parallel-group, Superiority Study to Compare the Efficacy of Augmented ACL Integration Via Platelet-rich-plasma Enriched Collected Autologous Bone Versus Standard ACL Technique","Inclusion Criteria:\n\n* Age 18-50 years\n* Primary ACL rupture\n* Time from injury to surgery: 4 weeks to 6 months\n* Single ACL rupture (isolated rupture)\n* ACL surgery with one of the participating senior surgeons\n* Informed Consent as documented by signature\n\nExclusion Criteria:\n\n* Concomitant ligamentous instability\u002Frupture\n* Requirement for Meniscus suture (partial resection accepted, hoop and roots remain intact)\n* Requirement for cartilage invasive treatment (debridement accepted)\n* Osteoarthritis at index knee joint\n* Leg axis deviation over 3° valgus or 4° varus\n* Claustrophobia (contra-indication for the MRI)\n* Women who are pregnant or breast feeding or intention to become pregnant during the study\n* Known or suspected non-compliance, drug or alcohol abuse\n* Inability of the patient to follow the study procedures, e.g. language problems, psychological disorders, dementia, etc.",{"count":151,"type":21},107,[24],"The purpose of this clinical study is to compare the outcomes of two surgical techniques for reconstruction of the anterior cruciate ligament (ACL) after a single, primary ACL rupture.\n\nThe main question to be answered is:\n\n\\- Does less widening of the tibial tunnel occur when a bone\u002FPlatelet rich plasma (PrP) composite material is placed directly into the tibial tunnel after fixation of the implant (experimental group) compared to the same surgery without the use of the composite material (control group)?\n\nParticipants will be randomized into one of the two groups and they will not know which group they belong to. After 12 months they will undergo CT, MRI, medical examination and functional knee testing. They will have a further medical examination and functional knee testing at 24 months. Patient Reported Outcomes will be collected before surgery, 6, 12 and 24 months after surgery.",[155],"Anterior Cruciate Ligament Tear",[157,158,159],"Anterior Cruciate Ligament Reconstruction","Platelet-Rich Plasma","Bone Tunnel Widening","2024-01-26",{"date":162,"type":33},"2024-01-29",{"date":164,"type":21},"2024-01",{"date":166,"type":21},"2027-08",{"name":39,"class":40},""]