[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":314},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,53,81,110,143,179,202,224,250,276,296],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100643122","the-effects-of-anesthesia-on-postoperative-cognitive-functions-in-patients-undergoing-sleeve-gastrectomy-100643122",false,"NCT07637357","The Effects of Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy","The Effects of Total Intravenous Anesthesia and Inhalational Anesthesia on Postoperative Cognitive Functions in Patients Undergoing Sleeve Gastrectomy","Inclusion Criteria:\n\nPatients of both sexes, Patients Aged between 18 and 65 years, Patients classified as ASA(American Society of Anesthesiologists) physical status I- III, Patients with a BMI (Body Mass Index) between 35 and 50 kg\u002Fm² scheduled to undergo sleeve gastrectomy as a type of bariatric surgery for the first time.\n\nExclusion Criteria:\n\nPatients classified as ASA physical status 4 or high, Patients with known allergy to any of the drugs used in the study, Patients with bleeding disorders, Patients with serum creatinine levels \\>2 mg\u002FdL, Patients with severe arrhythmias and EF\\\u003C30%, Patients with a known history of drug abuse are excluded.","ALL","18 Years","65 Years",{"count":20,"type":21},60,"ESTIMATED","3 Months","OBSERVATIONAL","In this study, the investigators want to examine the effects of intravenous anesthetic drugs and gases on cognitive functions in the postoperative period in individuals who will undergo surgery for obesity. The investigators believe that the anesthesia method we apply with inhalation gases is also as reliable method as total intravenous anesthesia for postoperative cognitive functions in these patients who undergoe sleeve gastrectomy.\n\nThe anesthesia method applied intravenously and with inahalational gases have been applied safely for many years. Comparisons between these two anesthesia technics in obese individuals and for postoperative cognitive dysfunctions are limited.\n\nStudies on the examination of cognitive functions in postoperative patients have gained momentum with the use of neuropsychiatric tests performed on patients who have undergone cardiac surgery and these tests have also been performed on individuals who have undergone non-cardiac surgery. And yet, similar declines in cognitive functions have been observed. For these reasons, the effects of surgery itself and anesthesia methods on cognitive functions have been studied up to date.\n\nIn this study, the investigators plan to evaluate patients who will undergo obesity surgery in both anesthesia methods by the recovery times from anesthesia and the residual effects of anesthesia, and after awakening they plan to evaluate their cognitive functions with neuropsychiatric tests that will be performed at certain intervals.",[26,27,28,29,30,31,32,33,34],"POCD - Postoperative Cognitive Dysfunction","Recovery Time","Postoperative Neurocognitive Disorder","Postoperative Delirium","Bariatric Sleeve Gastrectomy","Delayed Neurocognitive Recovery","Total Intravenous Anesthesia","Inhalational Anesthesia","Cognitive Functions",[36,37,38,39],"total intravenous anesthesia","inhalational anesthesia","sleeve gastrectomy","postoperative cognitive dysfunctions","RECRUITING","2026-06-04",{"date":43,"type":44},"2026-06-09","ACTUAL",{"date":46,"type":44},"2025-09-30",{"date":48,"type":21},"2026-07-30",{"name":50,"class":51},"Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":52},"100636413","the-effect-of-motor-imagery-on-upper-extremity-function-in-stroke-rehabilitation-100636413","NCT07565363","The Effect of Motor Imagery on Upper Extremity Function in Stroke Rehabilitation","The Effect of Motor Imagery on Upper Extremity Function in Stroke Rehabilitation: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Being aged 18 years or older\n* Having a diagnosis of ischemic or hemorrhagic stroke confirmed by computed tomography (CT) or magnetic resonance imaging (MRI)\n* Being in the late subacute phase (more than 3 months post-stroke) or chronic phase (more than 6 months post-stroke) following stroke onset\n* Presence of unilateral extremity hemiparesis\n* Upper extremity stage between II and V for both proximal and distal segments according to the Modified Brunnstrom Classification\n* A score of 21 or higher on the Mini-Mental State Examination (MMSE)\n\nExclusion Criteria:\n\n* Severe spasticity in the affected upper extremity, defined as a Modified Ashworth Scale score \\> 2\n* Presence of impaired consciousness, or severe hearing, visual impairment or global aphasia.\n* Musculoskeletal disorders affecting upper extremity motor function, such as fracture or arthritis in the affected upper limb",{"count":61,"type":21},51,"INTERVENTIONAL",[64],"NA","Stroke is one of the leading causes of mortality and disability worldwide. A proportion of individuals who experience a stroke fail to achieve the desired level of motor recovery in the affected upper extremity following rehabilitation, resulting in significant limitations in activities of daily living. After stroke, rehabilitation programs are essential to reduce disability and enhance functional outcomes.\n\nThis study aims to evaluate whether the addition of Motor Imagery (MI) to a standard rehabilitation program contributes to improvements in upper extremity motor function in individuals with stroke. MI is a mental practice technique in which individuals cognitively rehearse movements without physically performing them. Although the movement is not executed, the brain regions involved in the movement are activated.\n\nEligible participants will be randomly assigned to three groups. All groups will receive a standard physical therapy and rehabilitation program. The first group will receive only standard physical therapy and rehabilitation. The second group will receive, in addition to conventional therapy, 15 minutes of MI training three days per week, while the third group will receive 15 minutes of MI training five days per week. The total treatment duration for all groups is planned as 30 sessions.\n\nAssessments will be conducted at baseline, at the end of the treatment period, and again at the 12th week. This study is based on the hypothesis that adding MI practice to a conventional upper extremity rehabilitation program after stroke will contribute to improvements in activities of daily living and functional recovery, and that these effects may be associated with the frequency of the intervention.",[67],"Stroke Rehabilitation",[69,70,71,72],"Motor Imagery (MI)","Upper Extremity","Stroke","Rehabilitation","2026-06-03",{"date":75,"type":44},"2026-06-08",{"date":77,"type":44},"2026-05-01",{"date":79,"type":21},"2026-12-15",{"name":50,"class":51},{"id":82,"slug":83,"hasResults":11,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":87,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":91,"conditions":92,"keywords":96,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":52},"100639461","comparison-of-meta-peng-and-suprainguinal-fascia-iliaca-plane-block-in-hip-fractures-100639461","NCT07612761","Comparison of Meta-PENG and Suprainguinal Fascia Iliaca Plane Block in Hip Fractures","Comparison of the Effects of Ultrasound-Guided Meta-PENG Block and Suprainguinal Fascia Iliaca Plane Block in Patients Undergoing Hip Fracture Surgery Under Spinal Anesthesia","META-SIFI","Inclusion Criteria:\n\n* Age greater than 18 years\n* ASA physical status I-III\n* Scheduled to undergo hip fracture surgery under spinal anesthesia\n* Written informed consent obtained from the patient or the patient's legal representative\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* ASA physical status IV-V\n* Presence of central or autonomic nervous system disease\n* Known allergy to the drugs used in the study",{"count":90,"type":21},80,"This prospective observational single-center study will compare the effects of ultrasound-guided meta-PENG block and suprainguinal fascia iliaca plane block in patients undergoing hip fracture surgery under spinal anesthesia.\n\nHip fracture surgery can cause significant pain before, during, and after the operation. Regional anesthesia techniques may help reduce pain, improve positioning for spinal anesthesia, decrease the need for additional analgesics, and support earlier mobilization.\n\nPatients included in the study will be adults scheduled for hip fracture surgery under spinal anesthesia. According to routine clinical practice and the anesthesiologist's decision, patients will receive either ultrasound-guided meta-PENG block or ultrasound-guided suprainguinal fascia iliaca plane block. The study will not assign patients to a treatment group by randomization.\n\nThe main outcome will be pain during positioning for spinal anesthesia, measured using the Numeric Rating Scale. Additional outcomes will include postoperative pain at rest and during activity, additional analgesic consumption, patient satisfaction, mobilization time, and length of hospital stay.",[93,94,95],"Hip Fracture","Postoperative Pain","Regional Anesthesia",[97,98,99,100,101],"Hip fracture","Meta-PENG block","Suprainguinal fascia iliaca plane block","Postoperative analgesia","Regional anesthesia","2026-05-23",{"date":104,"type":44},"2026-05-29",{"date":106,"type":44},"2026-05-14",{"date":108,"type":21},"2026-12-31",{"name":50,"class":51},{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":4,"eligibilityCriteria":116,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":117,"enrollmentInfo":118,"targetDuration":4,"studyType":62,"phases":120,"briefSummary":121,"conditions":122,"keywords":124,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":52},"100632778","the-role-of-fascia-and-breathing-exercises-in-the-treatment-of-cervicogenic-headache-100632778","NCT07518108","The Role Of Fascia And Breathing Exercises In The Treatment Of Cervicogenic Headache","The Role Of Fascia And Breathing Exercises In The Treatment Of Cervicogenic Headache: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adults aged 18-60 years\n* Diagnosis of cervicogenic headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3)\n* Headache duration of at least 3 months\n* Presence of headache associated with cervical movement limitation or provoked by neck movement\n* Pain intensity of ≥3 on the Visual Analog Scale (VAS) at baseline\n* Ability to understand and comply with the study procedures\n* Willingness to participate and provision of written informed consent\n\nExclusion Criteria:\n\n* Presence of other primary headache disorders (e.g., migraine, tension-type headache, cluster headache)\n* Diagnosis of rheumatologic diseases (e.g., rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus)\n* Serious cervical spine pathologies (e.g., cervical myelopathy, spinal stenosis)\n* Presence of neurological deficits or central nervous system disorders\n* Received physical therapy for the cervical region within the past 3 months\n* Severe psychiatric disorders or cognitive impairment that may interfere with participation\n* Pregnancy\n* Cardiopulmonary conditions contraindicating exercise\n* Musculoskeletal disorders that may interfere with exercise adherence","60 Years",{"count":119,"type":21},72,[64],"This study aims to investigate the effect of specific exercise programs on individuals suffering from cervicogenic headaches, a type of headache originating from neck problems. While traditional physiotherapy is the standard approach, this research examines whether the addition of specific \"fascia-focused\" exercises or \"breathing exercises\" provides improved relief.\n\nFascia is a thin, protective membrane layer surrounding every muscle and organ in the body. In this study, participants will be divided into three groups. All participants will receive standard neck exercises and posture training. One group will perform dynamic exercises targeting the body's connective tissue (fascia) to improve flexibility and coordination. Another group will practice specific breathing techniques to help reduce muscle tension and stress-related triggers. The exercises will be administered to participants for 12 weeks.\n\nIt is expected that fascia exercises and breathing exercises will have positive effects on headaches as a result of the applied treatments.",[123],"Cervicogenic Headache",[125,126,127,128,129,130,131,123,132,133],"Thoracolumbar Fascia","Fascia Exercise","Breathing Exercise","Randomized Controlled Trial","Pain","Physical Therapy","Headache Impact Test","Fascia thickness","Ultrasound imaging","NOT_YET_RECRUITING","2026-04-18",{"date":137,"type":44},"2026-04-22",{"date":139,"type":21},"2026-04-20",{"date":141,"type":21},"2026-10-30",{"name":50,"class":51},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":151,"minAge":152,"maxAge":117,"enrollmentInfo":153,"targetDuration":4,"studyType":62,"phases":155,"briefSummary":156,"conditions":157,"keywords":162,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":52},"100631101","comparison-of-oral-dydrogesterone-and-vaginal-progesterone-in-menopausal-hormone-therapy-100631101","NCT07496294","Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy","Comparison of Oral Dydrogesterone and Vaginal Micronized Progesterone Regimens Combined With Transdermal Estradiol in Menopausal Hormone Therapy: A Prospective Randomized Controlled Trial","PRO-MHT","Inclusion Criteria:\n\n* Women aged 45-60 years\n* Postmenopausal status (absence of menstruation for ≥12 months)\n* Intact uterus\n* Presence of menopausal symptoms requiring menopausal hormone therapy\n* Willingness to participate and provide written informed consent\n\nExclusion Criteria:\n\n* Unexplained vaginal bleeding\n* History of breast cancer or endometrial cancer\n* Known hypersensitivity to study medications\n* History of thromboembolic disease (e.g., deep vein thrombosis or pulmonary embolism)\n* Severe liver disease\n* Uncontrolled hypertension\n* Any condition that, in the opinion of the investigator, makes participation inappropriate","FEMALE","45 Years",{"count":154,"type":21},200,[64],"Menopause is a natural stage in a woman's life that can be associated with symptoms such as hot flashes, night sweats, sleep problems, and vaginal dryness. Menopausal hormone therapy is commonly used to relieve these symptoms. In women with an intact uterus, progesterone must be used together with estrogen to protect the lining of the uterus.\n\nThe purpose of this study is to compare two commonly used progesterone treatment methods in women receiving menopausal hormone therapy. All participants will use transdermal estradiol gel, and they will be randomly assigned to receive either oral dydrogesterone or vaginal micronized progesterone.\n\nThis prospective randomized controlled study will evaluate the effects of these treatments on endometrial thickness, menopausal symptoms, vaginal health parameters, bleeding patterns, and quality of life over a 12-month follow-up period.\n\nThe results of this study may help determine the most appropriate progesterone regimen for women undergoing menopausal hormone therapy.",[158,159,160,161],"Menopausal Women","Menopausal Symptom Relief","Hormone Therapy","Menopausal Hormone Therapy",[163,164,165,166,167,168,169,170],"Menopausal hormone therapy","Dydrogesterone","Micronized progesterone","Transdermal estradiol","Progesterone route of administration","Endometrial thickness","Postmenopausal women","Randomized controlled trial","2026-03-23",{"date":173,"type":44},"2026-03-27",{"date":175,"type":21},"2026-04",{"date":177,"type":21},"2027-10",{"name":50,"class":51},{"id":180,"slug":181,"hasResults":11,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":185,"eligibilityCriteria":186,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":187,"enrollmentInfo":188,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":190,"conditions":191,"keywords":193,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":196,"startDateStruct":198,"completionDateStruct":199,"leadSponsor":201,"locationsCount":4},"100627796","dysregulation-of-the-soluble--klotho-fgf23-axis-in-hashimotos-thyroiditis-a-case-control-study-100627796","NCT07453290","Dysregulation of the Soluble α-Klotho-FGF23 Axis in Hashimoto's Thyroiditis: A Case-Control Study","The KLASH Study: Dysregulation of the Soluble α-Klotho-FGF23 Axis in Hashimoto's Thyroiditis - A Prospective Case-Control Study","klofgfhashi","Inclusion Criteria:\n\nAdults aged 18-65 years\n\nAbility to provide written informed consent\n\nHashimoto group: Diagnosis of Hashimoto's thyroiditis based on positive anti-thyroid peroxidase (anti-TPO) and\u002For anti-thyroglobulin (anti-TG) antibodies with compatible clinical\u002Fultrasound findings (as available)\n\nControl group: No history of thyroid disease or autoimmune disease; normal thyroid function tests (TSH and free T4 within reference range)\n\nExclusion Criteria:\n\nPregnancy or breastfeeding\n\nKnown chronic kidney disease (eGFR \\\u003C 60 mL\u002Fmin\u002F1.73 m²)\n\nActive infection or acute inflammatory condition within the past 4 weeks\n\nKnown malignancy under active treatment\n\nChronic inflammatory\u002Fautoimmune disease other than Hashimoto's thyroiditis (e.g., rheumatoid arthritis, SLE, IBD)\n\nUse of systemic glucocorticoids or immunosuppressive therapy within the past 3 months\n\nKnown parathyroid disease or disorders of calcium\u002Fphosphate metabolism\n\nCurrent use of medications strongly affecting mineral metabolism (e.g., phosphate binders, active vitamin D analogs)","80 Years",{"count":189,"type":21},150,"Hashimoto's thyroiditis (HT) is the most common autoimmune thyroid disease and is increasingly recognized as a condition associated with chronic low-grade systemic inflammation beyond thyroid hormone dysfunction. The soluble α-Klotho-fibroblast growth factor 23 (FGF23) axis plays a central role in mineral metabolism, inflammation, and aging-related pathways; however, its involvement in HT has not been adequately characterized.\n\nThis prospective case-control study aims to compare serum soluble α-Klotho and FGF23 levels between adults with Hashimoto's thyroiditis and age- and sex-matched healthy controls, and to investigate their associations with thyroid function parameters, inflammatory markers, and autoimmune burden. In addition, the FGF23\u002FsKlotho ratio will be evaluated as an integrated marker of functional imbalance within the Klotho-FGF23 axis.\n\nThe study seeks to determine whether Hashimoto's thyroiditis is associated with systemic dysregulation of the Klotho-FGF23 pathway independent of renal function and mineral metabolism.",[192],"Autoimmune Thyroiditis",[194],"Hashimoto Disease","2026-03-02",{"date":197,"type":44},"2026-03-05",{"date":195,"type":21},{"date":200,"type":21},"2026-05-20",{"name":50,"class":51},{"id":203,"slug":204,"hasResults":11,"nctId":205,"briefTitle":206,"officialTitle":207,"acronym":208,"eligibilityCriteria":209,"healthyVolunteers":210,"sex":16,"minAge":211,"maxAge":212,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":214,"conditions":215,"keywords":218,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":195,"lastUpdatePostDateStruct":220,"startDateStruct":221,"completionDateStruct":222,"leadSponsor":223,"locationsCount":4},"100627797","comprehensive-geriatric-assessment-in-adults-aged-40-years-and-older-living-with-hiv-100627797","NCT07453303","Comprehensive Geriatric Assessment in Adults Aged 40 Years and Older Living With HIV","Prospective Comparative Evaluation of Frailty, Sarcopenia, Nutritional Status, Cognitive Function, and Functional Performance in Adults Aged 40 Years and Older Living With HIV and Age- and Sex-Matched Healthy Controls","HIV-AGE40","Age ≥ 40 years\n\nConfirmed diagnosis of HIV infection (for HIV group)\n\nOn stable antiretroviral therapy for at least 6 months (for HIV group)\n\nHIV-negative status confirmed by medical history or testing (for control group)\n\nAbility to provide informed consent\n\nExclusion Criteria:\n\nAcute infection or hospitalization within the last 4 weeks\n\nKnown active malignancy under treatment\n\nSevere psychiatric disorder interfering with assessment\n\nSevere cognitive impairment preventing participation",true,"40 Years","99 Years",{"count":90,"type":21},"People living with HIV are experiencing longer life expectancy due to effective antiretroviral therapy; however, they may develop age-related conditions earlier than the general population. This prospective observational study aims to evaluate frailty, sarcopenia, nutritional status, cognitive function, and functional performance in adults aged 40 years and older living with HIV and to compare them with age- and sex-matched healthy controls.",[216,217],"Frailty","Sarcopenia",[219],"HIV Infections",{"date":197,"type":44},{"date":195,"type":21},{"date":139,"type":21},{"name":50,"class":51},{"id":225,"slug":226,"hasResults":11,"nctId":227,"briefTitle":228,"officialTitle":229,"acronym":230,"eligibilityCriteria":231,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":232,"targetDuration":4,"studyType":62,"phases":234,"briefSummary":235,"conditions":236,"keywords":239,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":242,"lastUpdatePostDateStruct":243,"startDateStruct":245,"completionDateStruct":247,"leadSponsor":249,"locationsCount":52},"100594784","effect-of-phenol-addition-to-laser-treatment-on-epithelialization-and-healing-process-in-pilonidal-sinus-100594784","NCT07023952","Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus","Effect of Phenol Addition to Laser Treatment on Epithelialization and Healing Process in Pilonidal Sinus: A Prospective Randomized Controlled Clinical Trial","PLEPS","Inclusion Criteria:\n\n* Age 18 years and older\n* Primary pilonidal sinus disease\n* Three or fewer pit counts\n* Willing to participate in the study and signed informed consent form\n* Able to attend follow-up visits\n\nExclusion Criteria:\n\n* Age under 18 years\n* More than three pit counts\n* Acute abscess presentation\n* Bilateral lateral extension\n* Recurrent pilonidal sinus disease\n* Immunocompromised patients\n* Patients unable to attend follow-up visits\n* Pregnancy (if applicable)\n* Severe comorbidities that contraindicate surgery under local anesthesia",{"count":233,"type":21},130,[64],"This study compares two treatment approaches for pilonidal sinus disease: laser treatment alone versus laser treatment combined with phenol application. Pilonidal sinus is a common condition that affects young adults and can cause significant discomfort and time off work.\n\nParticipants will be randomly assigned to receive either laser treatment only (Group A) or laser treatment plus phenol application (Group B). Both treatments are minimally invasive and performed under local anesthesia as day surgery procedures.\n\nThe main goal is to determine if adding phenol to laser treatment speeds up the healing process (epithelialization) and improves patient outcomes. We will measure healing time, pain levels, return to daily activities, and quality of life over a 3-month follow-up period.\n\nThis research may help develop more effective treatment protocols that reduce healing time and improve patient comfort for people with pilonidal sinus disease.",[237,238],"Pilonidal Sinus Disease","Laser Therapy",[240,241],"Minimally Invasive Treatment","Day Surgery","2025-06-14",{"date":244,"type":44},"2025-06-17",{"date":246,"type":44},"2025-05-01",{"date":248,"type":21},"2025-11-01",{"name":50,"class":51},{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":4,"eligibilityCriteria":256,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":257,"targetDuration":4,"studyType":62,"phases":258,"briefSummary":259,"conditions":260,"keywords":265,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":270,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":274,"leadSponsor":275,"locationsCount":52},"100566524","eoib-for-laparoscopic-cholecystectomy-100566524","NCT06656299","EOIB for Laparoscopic Cholecystectomy","Evaluation of Post-Operative Analgesic Efficacy of Bilateral External Oblique Intercostal Plane Block Versus Wound Site Infiltration Control Group in Patients Underwent Laparoscopic Cholecystectomy Surgery","Inclusion Criteria:\n\n* Patients aged 18 to 65 who will be scheduled for an elective laparoscopic cholecystectomy under general anesthesia\n* ASA (American Society of Anesthesiologists) I-II-III\n\nExclusion Criteria:\n\n* presence of coagulation disorder\n* infection at the injection site of the block\n* known allergy to local anesthetics\n* advanced hepatic, heart or renal failure\n* history of abdominal surgery or trauma\n* conversion of laparoscopic to open surgery\n* consumption of any pain killers within the 24 h before the operation\n* chronic opioid consumption\n* pregnancy\n* alcohol or drug abuse\n* body mass index (BMI) ≥ 35 kg m-2\n* Impairment of the patient's cognitive functions (such as Alzheimer's disease, dementia, etc.).\n* Cholecystectomy cases performed under emergency conditions.",{"count":20,"type":21},[64],"Laparoscopic cholecystectomy, while less painful compared to conventional methods, is still a surgery that can cause significant pain for patients. Preventing postoperative pain is crucial for reducing respiratory complications, shortening hospital stays, and increasing patient satisfaction. Interfascial plane blocks have been widely used for postoperative analgesia in recent years worldwide. The External Oblique Intercostal Plane Block is one of the interfascial plane blocks used in abdominal surgeries. In our study, we aimed to compare the postoperative pain scores of patients who underwent laparoscopic cholecystectomy under general anesthesia, specifically between those who received the external oblique intercostal plane block and those who had trocar entry site infiltration.",[261,262,263,264],"Cholecystitis","Cholecystitis, Acute","Cholecystitis, Chronic","Cholecystitis; Gallstone",[266,267,268,269],"External Oblique Intercostal Plan Block","Wound Infiltration","Laparoscopic Cholecystectomy","Postoperative pain","2024-10-30",{"date":272,"type":44},"2024-11-01",{"date":270,"type":44},{"date":248,"type":21},{"name":50,"class":51},{"id":277,"slug":278,"hasResults":11,"nctId":279,"briefTitle":280,"officialTitle":280,"acronym":4,"eligibilityCriteria":281,"healthyVolunteers":11,"sex":151,"minAge":17,"maxAge":4,"enrollmentInfo":282,"targetDuration":284,"studyType":23,"phases":4,"briefSummary":285,"conditions":286,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":52},"100555931","outcomes-of-karydakis-primary-closure-and-pit-picking-methods-in-the-treatment-of-pilonidal-sinus-a-prospective-study-in-women-100555931","NCT06518499","Outcomes of Karydakis, Primary Closure, and Pit Picking Methods in the Treatment of Pilonidal Sinus: A Prospective Study in Women","Inclusion Criteria:\n\n* Female patients 18 years old and older\n* Diagnosed with pilonidal sinus disease, having 3 or fewer pits.\n* No previous surgical treatment for pilonidal sinus.\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Pregnancy\n* Presented with acute abscesses\n* Patients with recurrent disease, Stage-R.\n* \\>3 pit\n* Collagen tissue disease\n* Exceed to navicular area\n* Lateral extension in both directions\n* Accidentally discovered (asymptomatic) sinus or with follow-up \\\u003C12 months",{"count":283,"type":21},145,"12 Months","Although there are many methods for the surgical treatment of pilonidal sinus disease, the number of studies specific to women is limited in the literature. In addition to post-treatment recurrence and complication rates in women, aesthetic results are also of great importance. This study will compare the Karydakis procedure, a flap method, and the Bascom's pit-pick procedure, a minimally invasive procedure, in terms of recurrence, complications and aesthetics, especially in female patients with three or fewer pits.",[287],"Pilonidal Sinus","2024-10-05",{"date":290,"type":44},"2024-10-08",{"date":292,"type":44},"2024-07-01",{"date":294,"type":21},"2026-08-20",{"name":50,"class":51},{"id":297,"slug":298,"hasResults":11,"nctId":299,"briefTitle":300,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":302,"targetDuration":284,"studyType":23,"phases":4,"briefSummary":304,"conditions":305,"keywords":306,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":308,"startDateStruct":309,"completionDateStruct":311,"leadSponsor":313,"locationsCount":52},"100555852","comparison-of-pit-picking-phenol-and-combined-pit-picking-and-phenol-applications-in-pilonidal-sinus-treatment-100555852","NCT06517472","Comparison of Pit Picking, Phenol and Combined Pit Picking and Phenol Applications in Pilonidal Sinus Treatment","Inclusion Criteria:\n\n* Having two pits or less\n\nExclusion Criteria:\n\n* With bilateral lateral extension,\n* Stage-R with recurrent disease\n* Number of pits more than three pits,\n* Collagen tissue disease,\n* Patients with a postoperative follow-up period of less than 12 months",{"count":303,"type":21},165,"Pilonidal sinus disease is a common condition, and treatment options and outcomes vary greatly. Chronic symptomatic pilonidal sinus disease (PSD) primarily affects young adults and causes work loss. In this study, three treatment methods will be performed: the minimally invasive pit-picking procedure, crystallized phenol application (CPT), and a combined method (minimally invasive pit-picking procedure and CPT). The aim of this study is to compare the effectiveness of these three methods, evaluate short- and long-term results, and determine treatment success, the incidence of postoperative complications, chronic pain levels, recurrence rates, and patient satisfaction. Additionally, the effects of these methods on hospital stay, wound healing time, and workforce loss will also be examined.",[287],[307],"Pilonidal sinus",{"date":290,"type":44},{"date":310,"type":21},"2024-10-01",{"date":312,"type":21},"2026-10-01",{"name":50,"class":51},""]