[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shanghai High Myopia Study Group\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":119},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,69,96],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100563464","artificial-intelligence-for-highly-myopic-cataract-100563464",false,"NCT06616506","Artificial Intelligence for Highly Myopic Cataract","AI-HMC","Inclusion Criteria:\n\nAxial length ≥ 26 mm and patients with high myopia complicated by cataracts who visit our hospital.\n\nPreoperative anterior segment photography and cataract severity assessment, along with fundus OCT examination, have been performed.\n\nIf surgical treatment is conducted, the postoperative follow-up period should be no less than 1 month.\n\nThere are no missing clinical data before and after the surgery.\n\nExclusion Criteria:\n\nPatients who are unable to cooperate with the required examinations for this study.","ALL",{"count":18,"type":19},500000,"ESTIMATED","OBSERVATIONAL","This study aims to establish a multi-center artificial intelligence model for the accurate calculation of intraocular lens and its clinical application in highly myopic cataract, so as to improve the accuracy of the prediction of postoperative diopter in highly myopic cataract patients.",[23,24,25,26,27,28],"Cataract","High Myopia","Myopia","Automatic Judgement","Risk Reduction","Diagnoses Disease",[30,31,32,33],"highly myopic cataract","artificial intelligence","cataract","big data","RECRUITING","2026-05-06",{"date":37,"type":38},"2026-05-11","ACTUAL",{"date":40,"type":38},"2016-01-01",{"date":42,"type":19},"2035-12-31",{"name":44,"class":45},"Shanghai High Myopia Study Group","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":58,"studyType":20,"phases":4,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":46},"100290540","shanghai-high-myopia-study-100290540","NCT03062085","Shanghai High Myopia Study","Visual Outcome Evaluation and Genetic Analysis: Shanghai High Myopia Study","Inclusion Criteria:\n\n* Clinical diagnosis of cataract\n* Must be able to cooperate with the ophthalmic examination\n\nExclusion Criteria:\n\n* Clinical diagnosis of mental illness\n* Mentally disabled","20 Years","100 Years",{"count":57,"type":19},60000,"5 Years","The purpose of this study is to evaluate the long-term visual outcome of the cataract surgery using a large-scale and comprehensive database of high myopic cataract and age-related cataract patients. The investigators will further investigate into the various genetic and environmental factors that may contribute to the pathogenesis of high myopic cataract.",[24,23,61,62],"Visual Outcome","Genetic Anticipation",{"date":37,"type":38},{"date":65,"type":38},"2015-01-01",{"date":67,"type":19},"2045-12-31",{"name":44,"class":45},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":5},"100625675","multicenter-study-of-transcranial-magnetic-stimulation-on-vision-restoration-100625675","NCT07425717","Multicenter Study of Transcranial Magnetic Stimulation on Vision Restoration","Effectiveness of TMS for Visual Restoration: a Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* between 45 and 70 years old\n* bilateral severe MMD (META-PM grades ≥ 3)\n* no prior TMS history or contraindications to TMS\n\nExclusion Criteria:\n\n* other significant ocular diseases, such as refractive media opacity, glaucoma, uveitis, ocular trauma, untreated retinal detachment, or lens dislocation\n* received anti-vascular endothelial growth factor treatment or other ocular surgeries within 3 months\n* history of epilepsy or family history of epilepsy, intracranial metal implants, or severe cerebrovascular diseases\n* mental illness, cognitive impairment (MMSE score \\\u003C 24), unable to communicate effectively\n* severe heart disease, liver or kidney dysfunction, or coagulation disorders\n* pregnant or lactating women\n* currently participating in other clinical trials.","45 Years","70 Years",{"count":79,"type":19},136,"INTERVENTIONAL",[82],"NA","The goal of this clinical trial is to learn if transcranial magnetic stimulation (TMS) works to restore vision in adults with severe retinal degeneration. It will also learn about the safety of TMS treatment. The main questions it aims to answer are:\n\n1. Does TMS treatment improve the visual function of participants?\n2. What medical problems do participants have when receiving TMS treatment? Researchers will compare TMS treatment to a sham stimulation (identical procedures using a sham coil without effective magnetic field output) to see if TMS treatment works to restore their vision.\n\nParticipants will:\n\nUndergoTMS treatment to a sham stimulation for consecutive 5 days Visit the clinic at 5 days, 4 weeks, 3 months, 6 months, 12 months after start of the treatment for checkups and tests",[85,86],"Retinal Degeneration","Vision Impairment and Blindness","NOT_YET_RECRUITING","2026-02-20",{"date":90,"type":38},"2026-02-23",{"date":92,"type":19},"2026-06-01",{"date":94,"type":19},"2029-05-31",{"name":44,"class":45},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":80,"phases":107,"briefSummary":108,"conditions":109,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":46},"100562266","evaluation-of-tms-visual-outcome-100562266","NCT06600932","Evaluation of TMS Visual Outcome","Effects of Transcranial Magnetic Stimulation on Visual Outcome in Patients After Cataract Surgery","Inclusion Criteria:\n\n* Post cataract surgery\n* Best-corrected visual acuity less than 0.1logMAR\n\nExclusion Criteria:\n\n* Diagnosed with cognitive impairment or mental disorders and unable to cooperate with treatment;\n* Diagnosed with significant opacity of refractive media that affects observation of visual function;\n* History of epileptic seizures;\n* Long term use of psychotropic drugs；\n* Metal implants in the body.","30 Years","80 Years",{"count":106,"type":19},200,[82],"The goal of this clinical trial is to learn if transcranial magnetic stimulation (TMS) can improve the visual outcomes in patients after cataract surgery. The main question it aims to answer is:\n\n• Does TMS improve the visual outcome in patients after cataract surgery? Researchers will compare TMS to the sham-controlled treatment (exposure to recorded sounds of pulses without real magnetic stimulation) to see if TMS works to improve the visual outcomes of patients after cataract surgery.\n\nParticipants will\n\n* Undergo TMS treatment or a sham-controlled treatment for consecutive 5 days.\n* Visit the clinic once every 2 weeks for checkups and tests.",[110],"Cataract Surgery Experience","2024-09-15",{"date":113,"type":38},"2024-09-19",{"date":115,"type":19},"2024-10",{"date":117,"type":19},"2026-10",{"name":44,"class":45},""]