[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shanghai Pudong New Area Gongli Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100641225","oropharyngeal-flushing-suction-tube-with-laryngoscope-for-stroke-associated-pneumonia-100641225",false,"NCT07647666","Oropharyngeal Flushing Suction Tube With Laryngoscope for Stroke-Associated Pneumonia","Translational Application of an Oropharyngeal Flushing Suction Tube Combined With Laryngoscope for Improving Prognosis in Stroke-Associated Pneumonia: A Prospective Randomized Controlled Trial","OFST-SAP","Inclusion Criteria:\n\n1. Confirmed acute ischemic stroke by cranial CT or MRI.\n2. Age 18 years or older.\n3. Glasgow Coma Scale score of 6 to 12.\n4. No artificial airway and no requirement for invasive mechanical ventilation at enrollment.\n5. Written informed consent provided by the participant or legally authorized representative.\n\nExclusion Criteria:\n\n1. Existing artificial airway or invasive mechanical ventilation at ICU admission or screening.\n2. Pre-existing pulmonary infection at enrollment, or definite extra-pulmonary organ or tissue infection during the study period.\n3. Hemorrhagic blood disorder, clinically significant coagulopathy, or bleeding risk precluding laryngoscopy.\n4. Oral or maxillofacial deformity impeding laryngoscope insertion.\n5. Cervical spine fracture, atlantoaxial instability, or other condition restricting neck extension or movement.\n6. Confirmed or suspected pregnancy.\n7. Irreversible critical illness with anticipated survival less than 28 days.\n8. Uncontrolled hypertension or recurrent malignant arrhythmias.\n9. Other conditions judged by investigators to make participation unsuitable.","ALL","18 Years",{"count":20,"type":21},120,"ESTIMATED","INTERVENTIONAL",[24],"NA","Stroke-associated pneumonia is a common and clinically important complication after acute ischemic stroke, especially in non-intubated patients with impaired consciousness and reduced cough or swallowing reflexes. Conventional oral or nasal suction may be insufficient for removing deep oropharyngeal secretions. This prospective randomized controlled trial will evaluate whether a patented oropharyngeal flushing suction tube combined with direct laryngoscopy reduces the 28-day incidence of stroke-associated pneumonia compared with laryngoscope-guided standard suction and conventional oral\u002Fnasal suction.",[27,28],"Acute Ischemic Stroke","Stroke-Associated Pneumonia (SAP)",[30,31,32,33,34],"Oropharyngeal Suction","Laryngoscope","Airway Management","Suction Tube","Aspiration Pneumonia","NOT_YET_RECRUITING","2026-06-17",{"date":38,"type":39},"2026-06-18","ACTUAL",{"date":41,"type":21},"2026-08-01",{"date":43,"type":21},"2029-07-31",{"name":45,"class":46},"Shanghai Pudong New Area Gongli Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":58,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100608956","real-world-study-on-preoperative-application-of-rezvilutamide-100608956","NCT07208292","Real-world Study on Preoperative Application of Rezvilutamide","RWS-GU001","Inclusion Criteria:\n\n* Pathological confirmation: Confirmed as prostate adenocarcinoma by ultrasound\u002FMRI-guided prostate biopsy, with ISUP grade ≥ 2 (Gleason score ≥ 7);\n* Clinical staging (based on AJCC 8th edition):High-risk localized: cT3a or PSA \\> 20 ng\u002Fml or Gleason score ≥ 8;Locally advanced: cT3b-4 or positive pelvic lymph nodes (cN1);\n* Surgical feasibility: Multidisciplinary team (MDT) assessment considers that R0\u002FR1 resection can be achieved;\n* Laboratory requirements:Hemoglobin ≥ 90 g\u002FL, platelets ≥ 100×10\\^9\u002FL;Liver function: ALT\u002FAST ≤ 2.5×ULN, bilirubin ≤ 1.5×ULN;Renal function: eGFR ≥ 30 mL\u002Fmin\u002F1.73m².\n\nExclusion Criteria:\n\n* Disease-related: Distant metastasis (M1, including bone metastasis or visceral metastasis);Pathology indicating neuroendocrine differentiation or small cell carcinoma component \\> 10%;\n* Treatment-related:Previous history of receiving radiotherapy, cryotherapy, or systemic chemotherapy for prostate cancer;History of other malignant tumors within 5 years (except non-melanoma skin cancer);\n* Comorbidities: Uncontrolled cardiovascular diseases (e.g., NYHA Class III heart failure, myocardial infarction within 6 months);History of severe epilepsy (requiring long-term use of anticonvulsant drugs);・Others:Known allergy to relugolix or LHRH analogs;Participation in other interventional clinical trials.","MALE",{"count":57,"type":21},115,"1 Year","OBSERVATIONAL","Real-world study on Preoperative Application of Rezvilutamide",[62],"Preoperative Evaluation",[64],"prostate cancer","2025-09-26",{"date":67,"type":39},"2025-10-06",{"date":69,"type":21},"2025-10-15",{"date":71,"type":21},"2027-07-15",{"name":45,"class":46},""]