[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shi Yun\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":68},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,45],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100523521","the-correlation-between-ovarian-function-and-serum-biomarkers-100523521",false,"NCT06096766","The Correlation Between Ovarian Function and Serum Biomarkers","Study on the Correlation Between Ovarian Function and Serum Biomarkers","Inclusion Criteria:\n\n1. The selection criteria for healthy individuals are follows.\n\n   * women aged 18-45.\n\n     * Basic FSH\\\u003C10IU\u002FL, and AMH is within the normal range.\n\n       * Regular menstruation.\n\n         * Agree and sign an informed consent form.\n2. The selection criteria for DOR patients are follows.\n\n   * women aged 18-45.\n\n     * For two consecutive menstrual cycles, 25 ≥ basal FSH ≥ 10IU\u002FL or AMH\\\u003C1.1ng\u002Fml.\n\n       * Agree and sign an informed consent form.\n3. Selection criteria for POI patients are follows.\n\n   * 18 ≤ females aged \\\u003C40 years old.\n\n     * Two consecutive menstrual cycles with basal FSH\\>25IU\u002FL or AMH\\\u003C1.1ng\u002Fml.\n\n       * Agree and sign an informed consent form.\n\nExclusion Criteria:\n\n1. Patients with congenital gonadal developmental abnormalities or a family history similar to \"early menopause\".\n2. Patients with acquired organic lesions or decreased ovarian function caused by ovarian surgery.\n3. Patients who have undergone artificial cycle therapy with Western medicine or other endocrine treatments within the past three months.\n4. Patients with severe primary diseases and mental disorders such as crdiovascular, cerebrovascular, liver, kidney, and hematopoietic system.\n5. Patients during lactation or pregnancy.\n6. Patients who are allergic to the drugs used in this study or have a history of allergic reactions to traditional Chinese medicine.\n\nThose who meet any of the above 5 criteria for DOR and POI will be excluded and not included in this study. The exclusion criteria for healthy subjects are as (1), (3), (4), and (5).",true,"FEMALE","18 Years","45 Years",{"count":21,"type":22},35,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to find differences in serum biomarkers between ovarian function and normal individuals.",[26,27,28,29,30,31],"Premature Ovarian Insufficiency","Diminished Ovarian Reserve","Biomarker","Copper","Ceruloplasmin","Aging","RECRUITING","2024-12-04",{"date":35,"type":36},"2024-12-09","ACTUAL",{"date":38,"type":36},"2023-10-25",{"date":40,"type":22},"2025-11-11",{"name":42,"class":43},"Shi Yun","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":51,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":44},"100542178","the-bone-metabolism-characteristics-of-premature-ovarian-insufficiency-100542178","NCT06339489","The Bone Metabolism Characteristics of Premature Ovarian Insufficiency","Explore the Bone Metabolism Characteristics of Premature Ovarian Insufficiency","POI","Inclusion Criteria:\n\nPatients diagnosed by Western medicine with premature ovarian insufficiency. 18 ≤ patients' age ≤ 39 years;. Patients who voluntarily participate in this study, sign an informed consent form.\n\nExclusion Criteria:\n\nPatients with congenital gonadal dysplasia or a family history similar to \"early menopause\".\n\nPOI patients with acquired organic lesions or ovarian surgery. Patients who have taken Western or herbal medicine artificial cycle therapy or other endocrine therapy in the past three months.\n\nPatients with serious primary diseases and mental disorders such as cardiovascular and cerebrovascular, liver, kidney and hematopoietic system.\n\nPatients who are breastfeeding or pregnant.","39 Years",{"count":55,"type":22},60,"Explore the bone metabolism characteristics of premature ovarian insufficiency.",[26,58,59],"Bone Diseases, Metabolic","Bone Mineral Density","2024-06-21",{"date":62,"type":36},"2024-06-25",{"date":64,"type":36},"2024-04-01",{"date":66,"type":22},"2025-02-01",{"name":42,"class":43},""]