[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shifa International Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":78},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100639574","personalized-meal-timing-and-walking-based-on-glucose-patterns-in-adults-with-prediabetes-100639574",false,"NCT07618663","Personalized Meal Timing and Walking Based on Glucose Patterns in Adults With Prediabetes","CGM-Phenotyped Circadian Glycemic Vulnerability Windows to Personalize Meal Timing and Postprandial Activity in Prediabetes : A Randomized Controlled Trial","CLOCK-PRIME","Inclusion Criteria:\n\n* Age 30 to 70 years\n* Prediabetes, defined as either:\n* HbA1c 5.7% to 6.4% within 3 months of screening, or\n* Fasting plasma glucose 100 to 125 mg\u002FdL on two separate occasions\n* Body mass index 23 to 40 kg\u002Fm²\n* Owns a smartphone compatible with study applications\n* Willing to wear a continuous glucose monitor and wrist activity monitor during the study period\n* Willing to record meals using timestamped meal-photo logging\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Current or prior diagnosis of type 1 diabetes or type 2 diabetes\n* Use of glucose-lowering medication within the past 3 months\n* Use of systemic corticosteroid medication within the past 3 months\n* Use of prescription weight-loss medication within the past 3 months\n* Current shift work\n* Transmeridian travel across more than 2 time zones within 4 weeks before enrollment\n* Known untreated or unstable sleep disorder, including obstructive sleep apnea, narcolepsy, or insomnia disorder\n* Pregnancy, planned pregnancy, or breastfeeding\n* Gastrointestinal disease or surgery likely to affect nutrient absorption\n* Current participation in a structured dietary or exercise intervention program\n* Estimated glomerular filtration rate less than 60 mL\u002Fmin\u002F1.73 m²\n* Inability or unwillingness to comply with continuous glucose monitoring, wrist actigraphy, meal logging, or study visits","ALL","30 Years","70 Years",{"count":21,"type":22},105,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will test whether glucose sensor data can be used to identify the time of day when adults with prediabetes are most likely to have high blood sugar after meals. Participants will first wear a continuous glucose monitor and wrist activity monitor and record meal times for 10 days. These data will be used to classify each participant's personal \"glycemic vulnerability window,\" such as morning, evening, or generally variable patterns.\n\nParticipants will then be randomly assigned to either personalized meal timing plus a short walk after their most vulnerable meal, or to an attention-matched control group receiving sleep hygiene and general step-count advice. The main outcome will be the change in post-meal glucose exposure during each participant's vulnerable window after 4 weeks.",[28,29,30],"Prediabetes","Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)","Prediabetes or Diabetes",[28,32,33,34,35],"Continuous Glucose Monitoring","Precision Lifestyle Medicine","Meal Timing","Glycemic Variability","RECRUITING","2026-05-24",{"date":39,"type":40},"2026-06-01","ACTUAL",{"date":39,"type":22},{"date":43,"type":22},"2026-07-15",{"name":45,"class":46},"Shifa International Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":47},"100578133","transforming-diabetes-care-pharmacist-led-education-and-its-impact-on-patient-knowledge-self-management-and-health-outcomes-100578133","NCT06807333","Transforming Diabetes Care: Pharmacist-Led Education and Its Impact on Patient Knowledge, Self-Management, and Health Outcomes","TRIPLE-CARE","Inclusion Criteria:\n\n* We will include all confirmed diabetic patients who visit the SIH endocrinology OPD Clinic during the study duration.\n\n  * Both male and female patients visiting the Endocrinology Unit of the hospital will be eligible.\n  * Patients with HbA1c levels greater than 8% will be included.\n  * Both follow-up and newly diagnosed patients will be considered.\n  * Patients who sign the informed consent form will be enrolled in the study.\n\nExclusion Criteria:\n\n* We will exclude patients with gestational diabetes mellitus (GDM).\n\n  * Patients with central obesity will not be included in the study.\n  * Type 1 diabetes mellitus (DM) patients under the age of 20 will be excluded.\n  * Patients with inadequate medical history will be excluded from participation.\n  * Patients with HbA1c levels less than 8% will not be included.\n  * Patients who do not provide informed consent or express a lack of interest in the study will be excluded.","18 Years","60 Years",{"count":58,"type":22},385,[25],"This interventional study is to evaluate the impact of pharmacist-led education on diabetic patients' knowledge, self-management, and overall health outcomes. Participants in this study will attend pharmacist-led educational sessions designed to improve their understanding of diabetes and self-care practices. Researchers will assess changes in patients' knowledge, self-management behaviors, and clinical health markers before and after the intervention. The study will compare pre- and post-intervention results to determine the effectiveness of pharmacist-led education in transforming diabetes care.",[62],"Diabetes Mellitus",[64,65,66,67,68],"Pharmacist","Patient Knowledge","Self-Management","Health Outcome","HbA1c","NOT_YET_RECRUITING","2025-01-29",{"date":72,"type":40},"2025-02-04",{"date":74,"type":22},"2025-02-01",{"date":76,"type":22},"2025-07-31",{"name":45,"class":46},""]