[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Shuxiu Wang\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100551360","application-of-thrive-in-burn-children-with-suspected-difficult-airway-100551360",false,"NCT06459076","Application of THRIVE in Burn Children With Suspected Difficult Airway","Application of Transnasal Humidified Rapid-insufflation Ventilatory Exchange (THRIVE) in Burn Children With Suspected Difficult Airway：A Single-center, Randomized Controlled Study","Inclusion Criteria:\n\n* \\\u003C 18 years\n* ASA Grade I \\~ III\n* Children with head, face and neck scald or burn or flame or electrical c hemical or other\n\nExclusion Criteria:\n\n* Refusal or failure to sign an informed consent\n* Proposed to transnasal intubation\n* Fracture of the nasal bone, nasal bleeding, nasal deformity or obstruction\n* Tracheotomy status or severe head, face and neck burn or burn scar (difficult airway)\n* Unsuitable for rapid sequence induction\n* Basicranial fracture\n* Cyanotic congenital heart defect\n* At risk of malignant hyperthermia\n* And is participating in other clinical studies","ALL","18 Years",{"count":19,"type":20},120,"ESTIMATED","INTERVENTIONAL",[23],"NA","In order to improve intubation conditions in burn children, our aim is to investigate the efficacy of transnasal humidified rapid-insufflation ventilatory exchange technique（THRIVE) in children aged between 0 and 18 years who with head, face, and neck injuries by fire, scalding, chemical, electric,explosions, and others. We hypothesise that THRIVE increases first attempt success without hypoxemia in intubation of children and compared with routine practice.\n\nDoes the THRIVE can prolong apnoea time and delay the onset of desaturation to increase the success rate of the first tracheal intubation without desaturation?\n\nResearchers will compare THRIVE group with Routine care group to see successful intubation on the first attempt without desaturation.\n\nParticipants will received intravenous anesthesia induction, followed by 2-3 minutes preoxygenation, before intubation, the mask was removed from the children's face and a THRIVE nasal plug was placed. During intubation, the Routine care group had no oxygen supply,and the THRIVE group will be maintained throughout the apnoeic period with selected flow rates during intubation attempts.",[26],"Intubation; Difficult or Failed",[28,29,30,31],"THRIVE","burn children","airway","intubation","NOT_YET_RECRUITING","2024-07-02",{"date":35,"type":36},"2024-07-05","ACTUAL",{"date":38,"type":20},"2024-07-01",{"date":40,"type":20},"2026-05",{"name":42,"class":43},"Shuxiu Wang","OTHER",""]