[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sindh Institute of Urology and Transplantation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":185},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,46,76,104,130,160],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100636829","impact-of-dialysis-duration-and-diuresis-on-bladder-capacity-and-compliance-in-end-stage-renal-disease-patients-awaiting-renal-transplant-100636829",false,"NCT07570771","IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT","ESRD","Inclusion Criteria:\n\n* Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD)\n* Patients on maintenance dialysis for a duration of 6 to 24 months\n* ESRD secondary to non-urological causes\n* Patients awaiting renal transplantation\n\nExclusion Criteria:\n\n* Patients with diabetes mellitus\n* Patients with neurogenic bladder\n* Patients with prior urological surgeries\n* Patients with active urinary tract infection\n* Patients with pre-existing lower urinary tract symptoms before dialysis\n* Patients on medications affecting lower urinary tract function\n* Patients with neurological or systemic diseases affecting bladder function","ALL","18 Years","65 Years",{"count":20,"type":21},87,"ESTIMATED","01 Weeks","OBSERVATIONAL","Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation.\n\nOur prospective observational study is designed to investigate how dialysis duration and residual urine output (diuresis) influence bladder capacity and compliance in ESRD patients who are waiting for kidney transplantation. The adult patients undergoing regular dialysis will be assessed clinically, and they will also be subjected to laboratory tests, imaging, and urodynamic studies.\n\nThrough this study, we aim to determine the frequency of bladder malfunction and its correlation with the length of dialysis and the amount of urine excretion. The results might enhance the pre-transplant workup and offer a basis for urological post-transplantation management that could minimize complications.",[26,27],"End-Stage Renal Disease Requiring Haemodialysis","Bladder Dysfunction",[29,30,31,32],"Dialysis Duration","Bladder Capacity","Bladder Compliance","Renal Transplant Candidates","RECRUITING","2026-04-29",{"date":36,"type":37},"2026-05-06","ACTUAL",{"date":39,"type":37},"2026-02-02",{"date":41,"type":21},"2027-02",{"name":43,"class":44},"Sindh Institute of Urology and Transplantation","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":57,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":45},"100636272","early-oral-hydration-in-relieving-postoperative-thirst-100636272","NCT07563530","Early Oral Hydration in Relieving Postoperative Thirst","Effectiveness of Early Oral Hydration in Relieving Postoperative Thirst in Patients Undergoing Urological Endoscopic Procedures: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Male and female patients aged 18-65 years.\n2. Scheduled for elective urological endoscopic procedures under general anesthesia.\n3. Day-care endoscopic procedures.\n4. ASA classification I-III.\n\nExclusion Criteria:\n\n1. Known gastrointestinal disorders contraindicating early oral hydration (e.g., peptic ulcer disease, hiatal hernia, irritable bowel syndrome, esophagitis, or prior gastrointestinal surgery).\n2. Inability to express thirst or communicate (e.g., language barrier, altered consciousness).\n3. Requirement for nasogastric suction.\n4. History of facial, oropharyngeal, or laryngeal surgery.\n5. Swallowing dysfunction or delayed gastric emptying (e.g., gastroparesis).\n6. Incomplete reversal of muscle relaxant at PACU admission (no adequate spontaneous breathing or protective airway reflexes).",true,{"count":55,"type":21},200,"INTERVENTIONAL",[58],"NA","This study aims to evaluate whether allowing early oral hydration on demand effectively relieves postoperative thirst and enhances patient satisfaction in individuals undergoing urological endoscopic procedures",[61,62],"Thirst; Due to Deprivation of Water","Patient Satisfaction",[64,65,66,67],"Postoperative","Thirst","Oral Hydration","Satisfaction","2026-04-25",{"date":70,"type":37},"2026-05-04",{"date":72,"type":37},"2026-04-18",{"date":74,"type":21},"2026-10-18",{"name":43,"class":44},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":56,"phases":86,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":95,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":45},"100632168","retrograde-intrarenal-surgery-versus-extracorporeal-shockwave-lithotripsy-100632168","NCT07510178","Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy","Role Of Retrograde Intrarenal Surgery Versus Extracorporeal Shockwave Lithotripsy In Lower Calyceal Calculi","Inclusion Criteria\n\n* Those patients will be included with lower calyceal renal stones and size up to 1.5 cm.\n* Patients' ages will be between 18 and 60 years.\n* Both genders will be included.\n\nExclusion Criteria:\n\n* Untreated Urine culture positive will be excluded\n* Patients using anticoagulants and females with pregnancies and those lactating will be excluded.\n* Anatomical abnormalities like horseshoe kidney, duplex system, pelvic kidney, malrotated kidney, calyceal diverticulum, steep infundibulopelvic angle, infundibular stenosis, long infundibular length\u002Fnarrow infundibular width, pelvic ureteric junction obstruction, ureterocele, and ureteral stricture will be excluded.","60 Years",{"count":85,"type":21},66,[58],"The study's aim is to determine which treatment modality, either ESWL or RIRS, is more effective in achieving stone clearance for lower calyceal calculi.\n\nInvestigators hypothesize that retrograde intrarenal surgery is better as compared to extracorporeal shockwave lithotripsy. It will target those patients suffering from kidney stones in lower calyces with sizes up to 1.5 cm in an open-label, randomized controlled trial.",[89,90],"Renal Stone","Stone in Calyceal Diverticulum",[92,93,94],"renal stone","lithotripsy","retrograde","NOT_YET_RECRUITING","2026-04-10",{"date":98,"type":37},"2026-04-15",{"date":100,"type":21},"2026-04-30",{"date":102,"type":21},"2026-10-30",{"name":43,"class":44},{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":53,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":111,"targetDuration":4,"studyType":56,"phases":113,"briefSummary":114,"conditions":115,"keywords":119,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":45},"100632196","comparison-of-stress-response-evoked-by-conventional-versus-videolaryngoscope-100632196","NCT07510542","Comparison of Stress Response Evoked by Conventional Versus Videolaryngoscope","Comparison of the Efficacy of Non-channelled Video Laryngoscopy Versus Direct Laryngoscopy in Terms of Stress Response and Intubation Time: a Single-blinded Randomized Controlled Trial","Inclusion Criteria:\n\n* ASA I \\& II\n* Age 18-60 years.\n* Preoperatively nonhypertensive and hemodynamically stable patients\n* Patients scheduled for elective procedures not involving airway surgeries\n* Patients with informed consent\n* Mallampati score I and II\n* Interincisor gap \\> 3 cms\n* BMI less than 30 kg\u002Fm²\n\nExclusion Criteria\n\n* Patient refusal\n* ASA III, IV \\& V\n* Hemodynamically unstable patients\n* Patients with Hypertension and Ischemic Heart Disease (whether controlled or uncontrolled)\n* Airway abnormalities, including congenital airway malformations \\& maxillofacial abnormalities\n* Head, neck or any facial traumas or history of prior head, neck or airway surgeries\n* Emergency procedures\n* Pregnancy",{"count":112,"type":21},124,[58],"Impact of using video laryngoscopy versus direct laryngoscopy technique in terms of improved hemodynamics post intubation and time taken for intubation.",[116,117,118],"Laryngoscopy","Stress Response","Duration",[116,120,121],"Stress response","Video laryngoscope","2026-04-01",{"date":124,"type":37},"2026-04-03",{"date":126,"type":37},"2026-03-05",{"date":128,"type":21},"2026-09-05",{"name":43,"class":44},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":136,"eligibilityCriteria":137,"healthyVolunteers":11,"sex":138,"minAge":17,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":56,"phases":142,"briefSummary":143,"conditions":144,"keywords":148,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":45},"100632319","single-versus-double-drains-in-the-axillary-and-pectoral-regions-after-modified-radical-mastectomy-100632319","NCT07512141","Single Versus Double Drains in the Axillary and Pectoral Regions After Modified Radical Mastectomy","Comparative Analysis of Quilting Sutures With a Single Axillary Drain Versus Double Drains in the Axillary and Pectoral Regions for the Prevention of Seroma After Modified Radical Mastectomy","SVDD","Inclusion Criteria:\n\n* All patients older than 18 years but less than 70 years of age,\n* Diagnosed with breast carcinoma.\n* All the patients undergoing upfront MRM,\n* All patients undergoing MRM post-neoadjuvant chemotherapy.\n\nExclusion Criteria:\n\n* Mastectomy \\& sentinel lymph node biopsy\n* Breast reconstruction surgery\n* Defect covering flaps","FEMALE","70 Years",{"count":141,"type":21},60,[58],"Normally, after this surgery, skin is stitched in the usual simple way, with no quilting, and two drains are put in to remove serosa, one under the arm and one on the chest. In this study, the investigator will use a different type of stitch called a quilting stitch, which helps stick the skin to the chest muscle so there is less serosa collection. The investigator will compare two groups:\n\n* Group A: Quilting stitches with two drains (one under the arm and one on the chest).\n* Group B: Quilting stitches with one drain only (under the arm).",[145,146,147],"Seroma Following Procedure","Infections","Pain, Postoperative",[149,150,151],"Seroma","Mastectomy","Breast","2026-03-30",{"date":154,"type":37},"2026-04-06",{"date":156,"type":37},"2026-03-27",{"date":158,"type":21},"2027-03-31",{"name":43,"class":44},{"id":161,"slug":162,"hasResults":11,"nctId":163,"briefTitle":164,"officialTitle":165,"acronym":4,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":167,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":169,"conditions":170,"keywords":173,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":177,"lastUpdatePostDateStruct":178,"startDateStruct":180,"completionDateStruct":182,"leadSponsor":184,"locationsCount":45},"100630875","difficult-airway-prediction-by-integrating-stop-bang-criteria-100630875","NCT07493356","Difficult Airway Prediction by Integrating STOP-BANG Criteria","Enhancing Difficult Airway Prediction in Obese Patients: Integrating STOP-BANG With Additional Airway Assessment Tools","Inclusion Criteria:\n\n* Male \\& Female aged 18-60 years.\n* Body mass index 30 or more\n* American Society of Anesthesiologists (ASA) status II-III.\n* Scheduled for elective surgery under general anesthesia with endotracheal intubation.\n\nExclusion Criteria:\n\n* Patients' refusal to participate.\n* American Society of Anesthesiologists (ASA) IV \\& V.\n* Neuromuscular diseases or facial abnormalities.\n* Cardiothoracic, head and neck, or emergency surgery.\n* Previously diagnosed with OSA (by polysomnography) will be excluded.\n* Any airway-related anatomical deformity (e.g., Down's syndrome).\n* History of radiation exposure.\n* Patient with mouth opening \\\u003C2 fingers",{"count":168,"type":21},233,"This study is being done to determine the diagnostic accuracy of the STOP-BANG questionnaire in predicting difficult mask ventilation and intubation among obese patients.\n\nDuring the preoperative assessment, eligible participants will be enrolled in the study. The modified Mallampati score, thyromental distance, mouth opening, and upper lip bite tests will be performed along with STOP-Bang scores.\n\nLater in the operating room, general anesthesia will be given, and bag-mask ventilation and intubation grade will be assessed and recorded. A correlation will be assessed between the difficult airway assessment findings, along with the STOP-BANG score and the bas-mask difficulty scores and intubation grades.",[171,172],"Ventilatory Defect","Intubation; Difficult or Failed",[116,174,175,176],"Ventilation of lungs","Bag-mask","General Anesthesia","2026-03-19",{"date":179,"type":37},"2026-03-25",{"date":181,"type":37},"2026-03-09",{"date":183,"type":21},"2026-09-08",{"name":43,"class":44},""]