[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Singapore Institute of Food and Biotechnology Innovation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":115},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,87],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100642924","the-savor-study-appetite-and-physiological-responses-100642924",false,"NCT07636369","The SAVOR Study: Appetite and Physiological Responses","Seniors' Appetite: Vibrant Opportunities for Revitalization (SAVOR)","SAVOR","Inclusion Criteria:\n\n* Postmenopausal female\n* Aged 65-74 years\n* Habitual breakfast consumer (consumes breakfast between 7am to 10am)\n* Willingness to consume meals and follow intervention protocol\n* English speaking\n\nExclusion Criteria:\n\n* BMI ≥ 27.5\n* Diagnosed with medical condition that may influence appetite or microbiome (e.g. diabetes, thyroid disorders, gastrointestinal diseases)\n* Currently taking any medications or supplements that may influence appetite or the microbiome (e.g. probiotics, antibiotics, appetite stimulants\u002Fsuppressants) one month prior to their first visit in consultation with study physician, PI and study team\n* Following a special diet for weight management (e.g. low-calorie, low carbohydrate)\n* History of bariatrics surgery\n* Intentional attempt to change body weight or composition\n* History of severe vasovagal syncope (blackouts or near faints) following blood draw\n* Drug abuse within last 5 years\n* Excessive alcoholic beverage consumption \\> 2 servings per day (1 serving defined as 360 mL beer, 150 mL wine or 45 mL distilled spirits)\n* Smoking (cigarette, e-cigarette, cigar, pipe, vape)\n* Engaging in habitual vigorous physical activity (as defined by physical activity questionnaire-PAQ)\n* Loose teeth or jaw pain\n* Not missing \\> 2 non-wisdom molars\n* Involvement in other clinical studies that may influence the outcome of the study\n* A study team member or their immediate family member",true,"FEMALE","65 Years","74 Years",{"count":22,"type":23},20,"ESTIMATED","INTERVENTIONAL",[26],"NA","The study aims to identify key physiological factors that differentiate older adults with healthy appetites from those experiencing appetite decline. The investigators hypothesize that seniors experiencing appetite decline will exhibit distinct oro-sensory, gastrointestinal, and hormonal profiles compared to seniors with healthy appetites, suggesting underlying biological mechanisms contributing to reduced appetite.",[29,30],"Anorexia of Aging","Malnutrition or Risk of Malnutrition",[32,33,34,35,36,37],"appetite decline","elderly","anorexia of aging","malnutrition","Asian seniors","appetite regulation","NOT_YET_RECRUITING","2026-06-03",{"date":41,"type":42},"2026-06-09","ACTUAL",{"date":44,"type":23},"2026-06",{"date":46,"type":23},"2026-10",{"name":48,"class":49},"Singapore Institute of Food and Biotechnology Innovation","OTHER_GOV",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":17,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":24,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":78,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":50},"100623524","sodium-rich-condiments-unifying-health-and-taste-100623524","NCT07397754","Sodium-rich COndiments Unifying Health and Taste","Scout","Inclusion Criteria:\n\n1. ≥ 50, \\\u003C 75 years old\n2. Male or postmenopausal female (self-reported)\n3. ≥ 50 kg body weight\n4. Systolic blood pressure (≥ 130, \\\u003C 160 mmHg) or diastolic blood pressure (≥ 85, \\\u003C 100 mmHg)\n5. Willing and able to follow intervention protocol\n6. Ability to identify basic tastes (determined by taste discrimination test)\n7. English speaking\n\nExclusion Criteria:\n\n1. Prescribed and taking medication which may affect study outcomes (i.e. for blood pressure management, blood thinning etc.) in consultation with study physician (Prof Melvin Leow) and PI(Dr Darel Toh)\n2. Type 1 or type 2 diabetes mellitus (i.e. fasting blood glucose ≥ 7.0 mmol\u002FL or HbA1c ≥ 6.5 %)\n3. Taking dietary supplements which may affect study outcomes one month prior to their first visit in consultation with study physician, PI and study team\n4. Obesity (BMI ≥ 27.5 kg\u002Fm2)\n5. History or known present diagnosis of hematological (G6PD and coagulation disorders), hepatic (hepatitis B and C), renal, gastrointestional or other relevant disease \u002F disorders which may affect the outcomes of interest in consultation with study physician, PI and study team\n6. History of arteriovenous shunt or mastectomy\n7. Women who are pregnant, lactating or planning pregnancy\n8. History or present diagnosis of HIV and\u002For tuberculosis\n9. History of severe vasovagal syncope (blackouts or near faints) following blood draw\n10. Drug abuse within last 5 years\n11. Excessive alcoholic beverage consumption \\> 2 servings per day (1 serving defined as 360 mL beer, 150 mL wine or 45 mL distilled spirits)\n12. Smoking (cigarette, e-cigarette, cigar, pipe, vape)\n13. Engaging in habitual vigorous physical activity (as defined by physical activity questionnaire-PAR)\n14. Allergic or intolerance to intervention foods.\n15. Dislike or unwilling to consume intervention foods\n16. Photophobic (sensitivity to intense lights and colours), particularly to intense red lights\n17. Has sinus problems problems that affect taste and smell\n18. Involvement in other clinical studies that may influence the outcome of the study\n19. An ASTAR Staff.\n20. A study team member or their immediate family member","ALL","50 Years","75 Years",{"count":62,"type":23},32,[26],"This research aims to develop an evidence-based classification for sodium-rich condiments (natremic index) based on their CVD-related risks. It is hypothesised that the acute cardiovascular and physiological response (effectively extrapolated to long-term CVD risks) to meals prepared with various sodium-rich condiments can be leveraged upon for the development of such an index that will systematically classify sodium-rich condiments based on the risk they present to cardiovascular health.",[66,67,68],"Elevated Blood Pressure","Vascular Health","Sensory Evaluation",[70,71,72,73,74,75,76,77],"sodium intake","natremic index","elevated blood pressure","cardiometabolic outcomes","condiments","Asian","vascular health","sensory evaluation","RECRUITING","2026-02-05",{"date":81,"type":42},"2026-02-09",{"date":83,"type":42},"2025-09-22",{"date":85,"type":23},"2026-09-22",{"name":48,"class":49},{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":17,"sex":95,"minAge":96,"maxAge":59,"enrollmentInfo":97,"targetDuration":4,"studyType":24,"phases":99,"briefSummary":100,"conditions":101,"keywords":103,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":4},"100564026","alternative-protein-satiety-study-apes-study-100564026","NCT06623812","Alternative ProtEin Satiety Study (APES Study)","Satiety Responses of Meals Consisting of Different Protein Sources","APES","Inclusion Criteria:\n\n* Healthy male\n* Aged between 21 and 50-year-old\n* Are of normal weight (BMI 18-25kg\u002Fm2)\n* Stable weight for the previous 12 months (\\<5kg weight fluctuation in the previous year)\n* Healthy dentition and ability to bite, chew and swallow normally\n* No history of pain or discomfort in jaw movements or excessive teeth clenching or grinding\n* No dental carries or periodontal disease\n* Own a mobile device with Apple iOS Operating System version 15.0 -17.3 or Android Operating System version 10-14\n* Have access to a data plan\n* Comfortable with needles and insertion of a Continuous Glucose Monitoring System device for 3-7 days\n\nExclusion Criteria:\n\n* Are a smoker\n* Have any dislikes, intolerances or allergies to foods or common food ingredients e.g. nuts, soya, wheat, gluten, cereal, fruits, biscuits, dairy products, rice, vegetable, meat, seafood, sugar and sweetener, gelatin, natural food colourings or flavourings (e.g. MSG), etc.\n* Have any specific dietary requirements and\u002F or restrictions (e.g. Vegan\u002F vegetarian, religious beliefs, lactose intolerance, calorie restricted diet etc.)\n* Known sensitivity to medical-grade adhesives\n* Bleeding disorders (e.g Hemophilia, von Willebrand disease etc.)\n* Have sinus problems that affect your taste and smell\n* Have known glucose-6-phosphate dehydrogenase (G6PD) deficiency\n* Are taking insulin or medication known to affect your appetite or metabolism\n* Have major chronic diseases such as heart disease, cancer or diabetes mellitus etc.\n* Have active Tuberculosis (TB) or currently receiving treatment for TB\n* Have any known Chronic Infection or known to suffer from or have previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV)\n* Are a member of the research team or their immediate family members. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted\n* Are enrolled in a concurrent research study judged not to be scientifically or medically compatible with this study","MALE","21 Years",{"count":98,"type":23},50,[26],"This project aims to study the effects of different protein quality (i.e. high vs. low) and protein sources (i.e. plant protein vs. conventional animal protein) on post-meal satiety and satisfaction. The protein quality score of meals will be calculated using the published digestible indispensable amino acid score (DIAAS). The proposed study will investigate the link between protein quality, protein source, and the post-meal satiety responses, using a realistic lunch meal approach, in humans. Other than the self-reported visual analogue scale (VAS) satiety response, the postprandial glucose dips (i.e. 2-3hours post-meal) will be collected by continuous glucose monitoring (CGMS) as an objective indicator of postprandial self-reported hunger and subsequent energy intake. In addition, the oral processing behaviours of participants will be captured and compared between the test meals.",[102],"Healthy Male Adults Participants",[104,105,106],"Satiety","Alternative Protein","Protein Quality","2024-09-30",{"date":109,"type":42},"2024-10-02",{"date":111,"type":23},"2024-10",{"date":113,"type":23},"2024-12",{"name":48,"class":49},""]