[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"SleepUp Tecnologia em Saúde Ltda\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":95},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,76],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100435373","sleepup-digital-cbti-based-platform-for-insomnia-100435373",false,"NCT04949360","SleepUp Digital CBTi-based Platform for Insomnia","Evaluation of SleepUp Digital CBTi-based Platform in the Treatment of Insomnia","Inclusion Criteria:\n\n* Literate Brazilian portuguese speakers.\n* Insomnia symptoms (as measured by ISI).\n* An Android-based smartphone or tablet with access to the Internet.\n\nExclusion Criteria:\n\n* Previous experience with CBTi.\n* Use of sleeping pills or any other treatment for insomnia for two or more days a week in the last three months.","ALL","20 Years","60 Years",{"count":20,"type":21},280,"ESTIMATED","INTERVENTIONAL",[24],"NA","Cognitive-Behavioral Therapy for insomnia (CBTi) is a well-established therapeutic intervention for insomnia. SleepUp provides a digital therapeutics platform based on CBTi and additional features. This clinical trial aims at analyzing the efficacy of the CBTi-based platform offered by SleepUp in reducing symptoms of insomnia and will be conducted in 2 phases.\n\nPhase 1\n\nThe sample will be composed of 160 individuals, both males and females, from 20 to 60 years old, with insomnia symptoms considered as at least mild. Those who accept to participate will be randomized and distributed in four groups:\n\n* Standard CBTi (CBTi-S): This treatment consists of an eight-week treatment composed by weekly and structure appointments with board-certified sleep psychologists. The appointments will be made remotely (video calls with psychologists).\n* Minimal intervention - Sleep hygiene (MI-SH): This group will receive an educational program on sleep hygiene through the SleepUp app. Its content covers topics that are also covered in the online CBTi sessions. This procedure is more adequate as a control than the commonly used no treatment or waiting list controls, due to the behavioral\n* Online CBTI (CBTI-O): This group will receive access to an eight-weeks CBTi-based treatment through the SleepUp app. The participants of this group will receive interventions equivalent to the standard in-person CBTi, but provided through a digital platform.\n* Online CBTi + additional features (CBTi-O+): This group will have access to the complete premium version of SleepUp platform. It includes those presented in the CBTi-O group and other therapeutic and complementary features (including meditation audios and videos, mindfulness therapy, relaxation soundtracks, sleep hygiene tips, virtual assistant, and telehealth.\n\nAll participants in all groups will be assessed periodically throughout the eight weeks of intervention with standard sleep questionnaires and sleep logs. Equivalent intervals will be applied to the MI-SH group.\n\nPhase 2\n\nThis phase will comprise 120 individuals, both males and females, from 20 to 60 years old, with insomnia symptoms considered as at least mild. Those who accept to participate will be randomized and distributed in three groups:\n\n* Minimal intervention - Sleep hygiene (MI-SH): This group will receive an educational program on sleep hygiene through the SleepUp app. Its content covers topics that are also covered in the online CBTi sessions. This procedure is more adequate as a control than the commonly used no treatment or waiting list controls, due to the behavioral\n* Online CBTI (CBTI-O): This group will receive access to an eight-weeks CBTi-based treatment through the SleepUp app. The participants of this group will receive interventions equivalent to the standard in-person CBTi, but provided through a digital platform.\n* Online CBTi + additional features (CBTi-O+): This group will have access to the complete premium version of SleepUp platform. It includes those presented in the CBTi-O group and other therapeutic and complementary features (including meditation audios and videos, mindfulness therapy, relaxation soundtracks, sleep hygiene tips, virtual assistant, and telehealth.\n\nAll participants in all groups will be assessed periodically throughout the eight weeks of intervention with standard sleep questionnaires and sleep logs. Equivalent intervals will be applied to the MI-SH group.",[27,28,29],"Insomnia","Sleep Disorder","Sleep Hygiene",[27,31,32,33],"Sleep","Cognitive-behavioral therapy","CBTi","RECRUITING","2025-12-20",{"date":37,"type":38},"2025-12-29","ACTUAL",{"date":40,"type":38},"2025-05-19",{"date":42,"type":21},"2026-12-01",{"name":44,"class":45},"SleepUp Tecnologia em Saúde Ltda","INDUSTRY",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":54,"sex":16,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":59,"studyType":60,"phases":4,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":46},"100534362","wearable-technologies-for-sleep-in-children-and-adolescents-100534362","NCT06237842","Wearable Technologies for Sleep in Children and Adolescents","Evaluation of Wearable Technologies for Sleep Monitoring in Children and Adolescents","Inclusion Criteria:\n\n* All genders\n* 3 to 18 years olnde\n* Resident in the city of São Paulo\n* Candidate to perfome a polysomnography test at the Sleep Laboratory of the Children's Institute of the Hospital das Clínicas of the University of São Paulo.\n\nExclusion Criteria:\n\n* None.",true,"3 Years","18 Years",{"count":58,"type":21},48,"1 Day","OBSERVATIONAL","This study aims to evaluate the viability of wearable and portable technologies for sleep staging in children and adolescents. The results will be compared with polysomnography, in order to achieve clinical and diagnostic validation. Three domains of devices will be used: movement sensors, wearable EEG band and pulse oximetry.\n\nThe project will include individuals between the ages of 3 and 18 who reside in São Paulo city and undergo a polysomnography test at the Sleep Laboratory of the Children's Institute of the Hospital das Clínicas of the University of São Paulo.",[31,63],"Pediatric Sleep Apnea",[65,66,67],"Pediatric sleep","Adolescent sleep","EEG","2025-11-24",{"date":70,"type":38},"2025-12-02",{"date":72,"type":38},"2024-11-22",{"date":74,"type":21},"2027-05-01",{"name":44,"class":45},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":60,"phases":4,"briefSummary":86,"conditions":87,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":89,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":93,"locationsCount":94},"100434927","actigraphy-wearable-eeg-band-and-smartphone-for-sleep-staging-100434927","NCT04943562","Actigraphy, Wearable EEG Band and Smartphone for Sleep Staging","Evaluation of the Viability of Actigraphy, Wearable EEG Band and Smartphone for Sleep Staging in Comparison With Polysomnography","FIRST STAGE (Healthy volunteers)\n\nInclusion Criteria:\n\n* Age between 20 and 80 years old\n* Living in the city of São Paulo, Brazil\n* No physical or intellectual disability that prevent attending to a in-lab polysomnography or understanding its instructions.\n\nExclusion Criteria:\n\n* Excessive daytime sleepiness (as measured by the Epworth Sleepiness Scale)\n* Poor sleep quality (as measured by the Pittsburgh Sleep Quality Index)\n* Insomnia symptoms at any level (as measured by the Insomnia Severity Index)\n* Symptoms of depression (as measured by the Beck Depression Inventory)\n* High risk to sleep apnea (as measured by the Stop-Bang questionnaire)\n* Presence of sleep-related symptoms (as measured by the UNIFESP (Federal University of São Paulo sleep questionnaire)\n* Self-reported abuse of alcohol, use of abuse drugs or use of medicine that might impact the normal sleep pattern (including hypnotics, benzodiazepines, antidepressants, corticosteroids, etc).\n* Self-reported chronic diseases\n* Diagnosis of any sleep disorders during the polysomnography\n\nSECONDS STAGE (volunteers with sleep disorders or complaints)\n\nInclusion Criteria:\n\n* Age between 20 and 80 years old\n* Living in the city of São Paulo, Brazil\n* No physical or intellectual disability that prevent attending to a in-lab polysomnography or understanding its instructions.\n* At least one sleep disorder or sleep complaint. . Among these, at least 30% of the sample should have moderate to severe insomnia (as measured by the insomnia severity index), 30% should have high risk to sleep apnea (as measured by the STOP-BANG questionnaire) and 70% should have excessive sleepiness scale (as measured by the Epworth sleepiness scale).\n\nExclusion criteria:\n\n* Absence of sleep disorders.","80 Years",{"count":85,"type":21},96,"This study aims to evaluate the viability of the combined use of wearable and portable technologies for sleep staging. The results will be compared with polysomnography, in order to achieve clinical and diagnostic validation. Three domains of devices will be used: Movement sensors, wearable EEG band and smartphones\n\nThe project will be composed of two stages:\n\nIn the first stage, the use of the combination of actigraphy and EEG will be used for sleep staging in a sample of 12 healthy volunteers from 20 to 80 years old, both genders and with no sleep disorders for each combination of ACT+EEG. Considering there will two of each (thus four combinations), the final sample will be composed of 48 individuals. Once recruited, evaluated according to the inclusion and exclusion criteria and consented with the terms of this study, the participants will be referred to the sleep lab, in which they will undergo a full night type-1 in lab polysomnography, following the setup recommended by the American Academy of Sleep Medicine. Concomitantly with the polysomnography, the participants will also use the combination of ACT+EEG.\n\nIn the second stage, the most successful combination tested in the first stage will be tested in a clinical sample, composed by 60 participants from both genders, from 20 to 80 years old and with at least one sleep disorder or complaint. Among these, at least 30% of the sample should have moderate to severe insomnia, 30% should have high risk to sleep apnea and 70% should have excessive sleepiness scale. All the procedures, including the polysomnography will be performed identically to the first step.",[31,27,88],"Sleep Apnea Syndrome, Obstructive",{"date":70,"type":38},{"date":91,"type":38},"2021-09-09",{"date":42,"type":21},{"name":44,"class":45},2,""]