[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Société Française d'Anesthésie et de Réanimation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":140},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,40,59,80,101,120],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100643046","diagnosis-and-treatment-of-late-neurological-ischemic-deficit-in-patients-suffering-from-subarachnoid-hemorrhage-100643046",false,"NCT07634172","Diagnosis and Treatment of Late Neurological Ischemic Deficit in Patients Suffering From Subarachnoid Hemorrhage.","Diagnosis and Treatment of Late Neurological Ischemic Deficit in Patients Suffering From Subarachnoid Hemorrhage","DINTESA-France","Inclusion Criteria:\n\n1. Age ≥ 18 years\n2. Primary diagnosis of subarachnoid hemorrhage due to rupture of a cerebral artery aneurysm, confirmed by cerebral CT angiography or intracranial angiography, requiring admission to an intensive care unit (ICU)\n3. No objection to the use of data in accordance with regulations.\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years\n* Primary diagnosis of subarachnoid hemorrhage sine materia, i.e. post-traumatic or caused by arteriovenous malformation or bleeding from a brain tumor.","ALL","18 Years",{"count":20,"type":21},1000,"ESTIMATED","OBSERVATIONAL","Recent studies state that patients affected by aneurysmal subarachnoid hemorrhage (aSAH) today survive longer because they are treated early. Unfortunately, patients often develop chronic disabling neurological deficits at a rate that is still unacceptable given the progress in the specific treatment of this pathology and the volume of systems of neurological monitoring available to date in Italy.\n\nThe main cause of unfavorable neurological outcome is delayed cerebral ischemia (DCI), often resulting from symptomatic vasospasm defined as delayed neurological ischemic deficit (DIND). The incidence of DIND is not defined and is difficult to diagnose early as there is no gold standard for identifying it, nor guidelines regarding the most effective treatment.\n\nGiven these gaps, the primary objective of this study is to describe the incidence of DIND in patients affected by aSAH, collecting information regarding the diagnostic imaging (neurological symptom on clinical examination or alteration on instrumental monitoring). Secondary objectives will be to evaluate the different therapeutic strategies adopted in the different participating centers and compare these strategies to mortality and short- and long-term functional neurological outcome. Furthermore, as there are no data in the literature, the Investigators want to describe the indications, usefulness and intensity of treatment in the aSAH patient in case of monitoring of parenchymal intracranial pressure.\n\nSame as italian study, with their consent. For France addition of medical imaging",[25,26],"Aneurysmal Subarachnoid Haemorrhage","Delayed Ischemic Neurological Deficit","NOT_YET_RECRUITING","2026-06-03",{"date":30,"type":31},"2026-06-08","ACTUAL",{"date":33,"type":21},"2026-06-15",{"date":35,"type":21},"2028-06-15",{"name":37,"class":38},"Société Française d'Anesthésie et de Réanimation","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":48,"conditions":49,"keywords":4,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":52,"lastUpdatePostDateStruct":53,"startDateStruct":55,"completionDateStruct":57,"leadSponsor":58,"locationsCount":39},"100607004","factors-associated-with-early-readmission-in-critical-care-100607004","NCT07182916","Factors Associated With Early Readmission in Critical Care","FRASC","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Hospitalized or admitted to the ICU\n\nExclusion Criteria:\n\n* Objection to the use of their data (by patient or a relative when applicable)\n* Patients under legal protection",{"count":20,"type":21},"The COVID-19 health crisis has highlighted pre-existing challenges in patient flow management within healthcare facilities, especially in critical care units. This has sparked debate regarding the sufficiency of critical care beds in France, while drawing attention to the lack of downstream structures. Inefficient patient flow, leading to bed occupancy bottlenecks, has been correlated with both critical care length of stay and morbidity. Unplanned early readmission to critical care further exacerbates these strains and prolongs hospital length of stay. Currently, no standardized criteria are available to guide safe discharge from critical care. A recent Delphi consensus study proposed a set of criteria, although largely subjective. The primary outcome of the present study is to identify factors associated with unplanned early readmission to critical care within 48 hours of discharge. Delayed discharge from critical care represents another major bottleneck contributing to system strain. The secondary outcome of this study is therefore to assess the proportion of critical care beds occupied by patients deemed ready for discharge by the medical team, as well as to analyze the reasons underlying such delayed transfers.",[50],"Early Readmission to the ICU","RECRUITING","2026-05-28",{"date":54,"type":31},"2026-05-29",{"date":56,"type":31},"2026-01-12",{"date":33,"type":21},{"name":37,"class":38},{"id":60,"slug":61,"hasResults":11,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":67,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":69,"conditions":70,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":39},"100633402","prognostic-factors-in-critically-ill-patients-admitted-after-caustic-ingestion-in-france-100633402","NCT07526220","Prognostic Factors in Critically Ill Patients Admitted After Caustic Ingestion in France","Prognostic Factors in Critically Ill Patients Admitted After Caustic Ingestion in France: a National Retrospective Multicentre Study","DATACAUSTIC","Inclusion Criteria:\n\n* age 18 years or older;\n* admission to a critical care unit for caustic ingestion within 72 hours;\n* no opposition to participation\u002Fdata collection\n\nExclusion Criteria:\n\n* Refus de participer à la recherche\n* Ingestion de caustique ne nécessitant pas une prise en charge en soins critiques",{"count":68,"type":21},100,"DATACAUSTIC is a national retrospective multicentre observational study designed to identify prognostic factors associated with outcomes in critically ill adult patients admitted after caustic ingestion in France.",[71],"Poisoning","2026-04-10",{"date":74,"type":31},"2026-04-13",{"date":76,"type":21},"2026-04-15",{"date":78,"type":21},"2027-06-30",{"name":37,"class":38},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":84,"acronym":85,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":89,"conditions":90,"keywords":4,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},"100535867","perioperative-hemostasis-management-in-liver-transplantation-100535867","NCT06257407","Perioperative Hemostasis Management in Liver Transplantation","HEMOTRANSPLANT","Inclusion Criteria:\n\n* Patients aged 18 or over\n* Liver transplant patient\n\nExclusion Criteria:\n\n* Multi-organ transplantation\n* Protected populations: under guardianship or curatorship\n* Patients not affiliated to a social security scheme",{"count":88,"type":21},1200,"Liver transplantation (LT) is a surgery with risk of bleeding. Several risk factors have been identified: complex dissection, portal hypertension, history of ascites fluid infections, history of surgical procedures, pre-existing complex hemostatic disorders and those acquired during the procedure. Diffuse bleeding can occur at any time during the 3 phases of surgery: dissection, anhepatic and neohepatic. However, intraoperative bleeding and transfusion requirements remain difficult to predict. Current predictive models are based in particular on preoperative characteristics and do not take into account the course and different phases of the operation.\n\nThe need for transfusions has largely decreased over the last 20 years, and currently around 20-25% of patients are transfused (transfusion of at least 1 blood product during LT). However, massive transfusion is necessary in 10% of LT. The European Society of Anaesthesiology (ESA) has issued recommendations on the management of severe bleeding during surgery. However, these recommendations are not specific to LT. Moreover, transfusion strategies vary widely from one center to another. The implementation of protocols within teams dedicated to LT has led to a reduction in bleeding and transfusion, with or without the use of viscoelastic testing.\n\nIntraoperative bleeding and transfusion requirements, as well as postoperative thromboembolic complications, remain difficult to predict. Predictive models of bleeding risk have been developed, but they are based solely on preoperative characteristics and do not take into account the course and various phases of the operation. In addition, new methods such as Bayesian inference or machine learning have been developed, and seem capable of providing different information from that obtained by conventional models.\n\nThe overall aim of this prospective multicenter observational study is to investigate the risk factors for bleeding and thrombosis in per- and post-operative LT using different predictive methods, and to describe the management of bleeding and post-operative anticoagulation in metropolitan France.",[91],"Liver Transplant; Complications","2026-03-27",{"date":94,"type":31},"2026-04-02",{"date":96,"type":31},"2024-10-17",{"date":98,"type":21},"2026-12-31",{"name":37,"class":38},16,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":110,"conditions":111,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":119,"locationsCount":39},"100617362","impact-of-implementing-a-national-classification-of-surgical-emergencies-on-postoperative-morbidity-and-mortality-a-prospective-multicenter-observational-study-after-implementation-100617362","NCT07317635","Impact of Implementing a National Classification of Surgical Emergencies on Postoperative Morbidity and Mortality: a Prospective Multicenter Observational Study After Implementation.","CLASSES","Inclusion Criteria:\n\n* Adults (≥18 years) undergoing non-cardiac emergency surgery, defined as surgery with a preoperative anesthetic consultation performed less than 48 hours before the surgical procedure.\n\nPatient managed in a University Hospital (Centre Hospitalo-Universitaire) or General Hospital (Centre Hospitalier Général).\n\nPatients must receive initial management and diagnosis in the emergency department of the investigating center.\n\nExclusion Criteria:\n\n\\-",{"count":109,"type":21},2500,"The ACUTE committee of the French Society of Anesthesia and Intensive Care (SFAR), in consultation with surgical societies, has developed a national classification of surgical emergencies to define the ideal time to surgery for each indication.\n\nThe goal is to integrate this classification with a cognitive aid to improve patient triage and reduce waiting times for emergency surgery.\n\nThis classification will be presented at the 2026 SFAR Congress and as a practical decision-making tool.\n\nA prospective, multicenter study will then evaluate its impact by measuring the rate of severe postoperative complications at 30 days using the Comprehensive Complication Index (CCI).\n\nThe study will include 2500 patients over two-week periods between February and June 2027.\n\nExpected benefits include reduced patient morbidity and hospital stay, along with better emergency surgery planning and standardization across healthcare centers.",[112],"Surgical Emergencies","2025-12-19",{"date":115,"type":31},"2026-01-05",{"date":117,"type":21},"2026-02-02",{"date":78,"type":21},{"name":37,"class":38},{"id":121,"slug":122,"hasResults":11,"nctId":123,"briefTitle":124,"officialTitle":124,"acronym":125,"eligibilityCriteria":126,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":127,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":128,"conditions":129,"keywords":4,"overallStatus":51,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":139},"100575148","icu-management-of-brain-dead-donors-before-multi-organ-procurement-and-factors-associated-with-the-number-of-organs-retrieved-100575148","NCT06768515","ICU Management of Brain-Dead Donors Before Multi-Organ Procurement and Factors Associated With the Number of Organs Retrieved","DONOR-OBS","Inclusion Criteria:\n\n* Patients over 18 years of age, hospitalized in the ICU\n* In a state of brain death\n* No objection to organ donation during their lifetime\n* Patients with social security coverage\n\nExclusion Criteria:\n\n* Objection to the use of their data during their lifetime\n* Registration in the national refusal registry",{"count":20,"type":21},"Solid organ transplantation is the treatment of choice for end stage organ failure to improve patients' quality of life and survival. Each year, more than 5,000 solid organ transplants are performed in France, mainly from brain death donors (BDD).\n\nApproximately 1,500 BDD donors have one or more organs removed each year. Despite the growing demand for transplanted organs, the number of organs available from deceased donors has remained stable over the past few decades. This highlights the need to optimize the management of potential BDD, in order to increase both the quality and number of transplanted organs. Several studies have found an association between the characteristics and management of BDD donors and the number of organs, or even the function of transplanted organs. Data suggest that hemodynamic, respiratory, and metabolic therapeutic targets during BDD management prior to multi-organ procurement were associated with a higher number of transplanted organs compared to standard care. However, this has never been confirmed in a French population. Furthermore, while the impact of these therapeutic goals has been studied after the donor is in a state of brain death, the events occurring in the ICU before reaching brain death status and their impact on the number of organs retrieved have not been investigated. Lastly, the intensity of the therapeutic interventions used to achieve these goals, and certain management delays, have only been partially studied.\n\nOur hypothesis is that achieving a bundle of therapeutic goals, and the intensity of the interventions used to reach these goals, both before and after BDD, are associated with a greater number of organs retrieved.",[130],"Death, Brain","2025-05-13",{"date":133,"type":31},"2025-05-16",{"date":135,"type":31},"2025-04-23",{"date":137,"type":21},"2026-02-15",{"name":37,"class":38},2,""]