[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Société d'Exploitation des Thermes d'Amnéville\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100620830","therapeutic-efficacy-of-the-phlebology-oriented-thermal-cure-at-the-saint-eloy-thermal-center-in-the-treatment-of-symptoms-of-severe-chronic-venous-insufficiency-100620830",false,"NCT07362719","Therapeutic Efficacy of the Phlebology-oriented Thermal Cure at the Saint-Eloy Thermal Center in the Treatment of Symptoms of Severe Chronic Venous Insufficiency","AMNEVILLE-PHL","Inclusion Criteria:\n\n* Adult male or female (≥ 18 years of age).\n* Patients with severe chronic venous insufficiency of the lower limbs (C4a,b,c - C5 according to the CEAP (Clinical manifestations, Etiology, Anatomic distibution, Pathophysiology) classification (2020 revision) for at least one of the legs) confirmed by venous Doppler ultrasound of the lower limbs.\n* Patients with an indication for a thermal cure exclusively focused on phlebology.\n* Patients available to participate in a 3-week consecutive thermal cure at the Saint-Eloy Thermal Center, followed by 6 months of clinical follow-up, in accordance with the protocol schedule.\n* Patients available to attend the visits scheduled in the protocol and able to complete the data collection documents.\n* For women of childbearing age: patient using effective contraception.\n* Patient affiliated with a health insurance plan or beneficiary (Art. L.1121-8-1, French Public Health Code).\n* Patient who has given their informed consent in writing regarding their participation in the protocol.\n\nExclusion Criteria:\n\n* Patients with a contraindication to thermal cure.\n* Patients who have participated in thermal cure (regardless of type) within the last 9 months.\n* Patients who have had an ulcer on their lower limbs that has healed within the last 3 months.\n* Patients without venous trophic disorders of the lower limbs, and in particular patients with isolated class C3 chronic venous insufficiency or less in both lower limbs.\n* Patients with an open ulcer on a lower limb (class C6).\n* Patients for whom interventional venous treatment is due to begin within the next 6 months.\n* Patients scheduled to undergo orthopedic surgery on the lower limbs within the next 6 months.\n* Patients who are unable to walk.\n* Patients with a known allergy to sulfur.\n* Patients with any medically significant findings or significant history that may impact safety, interpretation of results, and\u002For subject participation in the study at 6 months, in the investigator's opinion.\n* Patients simultaneously participating in another clinical trial or who have participated in another clinical trial for which the exclusion period has not ended.\n* Vulnerable persons (Art. L.1121-5 to 8, and L1122-1-2, French Public Health Code).","ALL","18 Years",{"count":19,"type":20},84,"ESTIMATED","INTERVENTIONAL",[23],"NA","Chronic venous insufficiency (CVI) is a common progressive vascular disease that affects nearly one-third of the French population. Despite considerable advances in the treatment of chronic venous insufficiency, this condition remains a burden for patients and national healthcare systems.\n\nBalneotherapy-which includes thermal cures-is part of the therapeutic arsenal used in the treatment of chronic venous insufficiency. It is a relatively effective alternative with a relatively low cost compared to drug or surgical treatments. Phlebology is a thermal treatment orientation recognized by the French social security system.\n\nThe Saint-Eloy Thermal Center is listed among the thermal stations approved by the French Ministry of Health. It currently uses thermal water from Amnéville-les-Thermes to treat rheumatological and respiratory conditions, and wants to expand its range of orientations by adding phlebology. The AMNEVILLE-PHL study therefore aims to evaluate the efficacy and safety of the Saint-Eloy thermal cure for phlebology in patients suffering from severe chronic venous insufficiency.",[26],"Venous Insufficiency of Leg",[28,29,30,31,26],"Severe chronic venous insufficiency","Thermal cure","Phlebology","Balneology","RECRUITING","2026-02-27",{"date":35,"type":36},"2026-03-02","ACTUAL",{"date":33,"type":36},{"date":39,"type":20},"2027-05",{"name":41,"class":42},"Société d'Exploitation des Thermes d'Amnéville","OTHER",""]