[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sormland County Council, Sweden\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100548042","behavioral-activation-for-the-prevention-and-treatment-of-depression-in-older-adults-in-a-municipal-context-100548042",false,"NCT06415838","Behavioral Activation for the Prevention and Treatment of Depression in Older Adults in a Municipal Context","Behavioral Activation for the Prevention and Treatment of Depression in Older Adults in a Municipal Context: a Randomized Controlled Trial","DePrevent","Inclusion Criteria:\n\n* 65 years or older\n* 5 points or above on the Geriatric Depression Scale 15, GDS-15\n* Fluent in written and spoken Swedish\n* Consents to participate in the trial\n\nExclusion Criteria:\n\n* Not able to use the patient materials due to visual impairment\n* Not able to communicate with therapist due to hearing impairment\n* Diagnosis of major neurocognitive disorder\n* Below 25 points on the Mini Mental State Examination, MMSE\n* Elevated suicide risk\n* Current substance- or alcohol use disorder\n* Previous or current psychotic disorder\n* Previous or current bipolar disorder\n* Ongoing psychological treatment\u002Fpscyhotherapy","ALL","65 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this randomized clinical trial is to investigate if a brief psychological treatment called Behavioral Activation (BA) works to prevent and treat depression in older adults in a municipal context in Sweden. It will also learn about the patients' and therapists' experiences of the BA-treatment.\n\nThe main questions it aims to answer are if the BA-treatment has an effect on the short and long term on:\n\n* Depressive symptoms\n* Anxiety symptoms\n* Self-rated activation\n* Functional ability\n* Loneliness\n* Self efficacy\n* Mental wellbeing\n* Quality of life\n* Need for community care services\n\nAll participants will continue their care as usual (CAU), and half of the participants will be randomized to receive a five-session BA-treatment spread over two months as an add-on to CAU. All participants will answer a questionnaire in the beginning of the study, after two months, and after 3-, 6- and 12 months.",[27,28],"Depression","Depressive Symptoms",[30,31,32,33,34],"Behavioral activation","Behavior therapy","Psychological treatment","Older adults","Geriatric","RECRUITING","2024-12-11",{"date":38,"type":39},"2024-12-16","ACTUAL",{"date":41,"type":39},"2024-06-27",{"date":43,"type":21},"2026-08",{"name":45,"class":46},"Sormland County Council, Sweden","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":47},"100525843","metacognitive-training-for-negative-symptoms-100525843","NCT06127004","Metacognitive Training for Negative Symptoms","Metacognitive Training for Negative Symptoms (MCT Minus)","Inclusion Criteria:\n\n* Over the age of 18\n* Clinical diagnosis of schizophrenia, delusional disorder or non-affective psychosis\n* Resident in Region Sörmland, Region Västmanland or Region Uppland\n\nExclusion Criteria:\n\n* Evidence of severe organic brain dysfunction\n* Learning disabilities\n* Difficulty with the Swedish language\n* Visual and\u002For hearing impairment\n* Being unable or unwilling to provide written informed consent","18 Years",{"count":57,"type":21},90,[24],"There is a clear rationale for developing interventions targeting negative symptoms of schizophrenia as these are a stronger indicator of current and future functioning than positive symptoms and because they respond poorly to medication and existing psychological interventions. This is reflected in the NIMH-MATRICS consensus statement that emphasised that persistent negative symptoms represent an unmet therapeutic need for patients suffering from schizophrenia.\n\nThe purpose of this study is to evaluate, in a scientific manner, the intervention developed by Swanson et al. 2021: Metacognitive Training (MCT) Minus. The MCT was adapted to target negative symptoms in psychotic disorders (e.g. schizophrenia, schizoaffective or non-affective functional psychosis) as the original version of the intervention focused exclusively on positive symptoms. The specific aim is to study whether MCT Minus is a promising treatment for the intended population in terms of reductions in negative symptoms, severity of defeatist attitudes, internalised stigma, and depression as well as improvements in reflective ability and overall functioning.\n\nThe research will add to existing research by identifying and measuring potential mechanisms of change for negative symptoms (i.e., defeatist attitudes, reflective functioning, stigma and depression). It will also add to the existing evidence base by measuring whether the cognitive biases addressed in MCT lead to changes in the wider conceptualisation of metacognition used elsewhere and whether the promising results seen in the feasibility study of MCT Minus can be replicated in a randomised controlled trial (RCT) with a control group and a blinded assessor. The researchers also hope to replicate the findings of a previous study, where MCT was found to be related to the modulation of default-mode network (DMN) homogeneity in schizophrenia, an area thought to be involved in self- and other-reflectivity.",[61],"Negative Symptoms in Schizophrenia","2024-02-05",{"date":64,"type":39},"2024-02-06",{"date":66,"type":39},"2024-01-01",{"date":68,"type":21},"2032-12",{"name":45,"class":46},""]