[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"St Vincent's University Hospital, Ireland\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":4,"briefSummary":21,"conditions":22,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100638437","chemokeyp-a-feasibility-study-for-realtime-safety-data-capture-for-potential-serious-adverse-drug-events-100638437",false,"NCT07592234","Chemokeyp: A Feasibility Study for Realtime Safety Data-Capture for Potential Serious Adverse Drug Events","Chemokeyp: A Feasibility Study to Evaluate and Further Develop Patient Safety Software Enabling Efficient and Effective Information Exchange for Patients Undergoing Systemic Cancer Treatment Who Access Emergency or Unscheduled Care.","Inclusion Criteria:\n\n* Patient undergoing treatment for cancer at SVUH\n\nExclusion Criteria:\n\n* Presence of a condition(s) or diagnosis, either physical or psychological, or physical exam finding that precludes participation (inability to give informed consent)","ALL",{"count":18,"type":19},100,"ESTIMATED","OBSERVATIONAL","Chemokeyp is a feasibility study testing a secure ED-Oncology interface for patients receiving chemotherapy who may present to unscheduled care with possible treatment-related complications.\n\nParticipants are enrolled through Oncology and issued a medical-alert-style wristband with a QR code. If they attend the Emergency Department, staff can scan the QR code, access a generic study landing page, and, after SVUH authentication, complete a short structured checklist about possible serious adverse events such as infection, chest pain, vomiting, syncope, or other red-flag symptoms.\n\nThe platform is designed as a secure research data-capture portal, not an electronic health record or clinical documentation system. It does not read from or write to the hospital EHR, does not provide clinical decision support, and does not change usual clinical care. Data entered by ED clinicians are limited to predefined structured fields for research and safety-signal feasibility purposes.\n\nThe study will assess whether ED clinicians can complete the checklist in real time, whether the information can support earlier notification to the research\u002Ftrial team, and whether this data accurately corresponds with verified serious adverse events. If feasible, Chemokeyp could help improve communication between Oncology, Emergency Medicine, and trial teams, supporting safer care for patients on chemotherapy and informing future development of ED-oncology digital safety tools.",[23,24,25,26],"Serious Adverse Events","Patient Safety","Pharmacovigilance","Oncology","RECRUITING","2026-05-11",{"date":30,"type":31},"2026-05-18","ACTUAL",{"date":33,"type":31},"2026-02-01",{"date":35,"type":19},"2027-01-01",{"name":37,"class":38},"St Vincent's University Hospital, Ireland","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":11,"sex":16,"minAge":47,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":50,"phases":51,"briefSummary":53,"conditions":54,"keywords":57,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":4},"100568773","efficacy-of-topical-5-fluorouracil-vs-calcipotriol-as-photodynamic-therapy-pre-treatment-for-field-actinic-keratoses-100568773","NCT06685588","Efficacy of Topical 5-Fluorouracil Vs Calcipotriol As Photodynamic Therapy Pre-treatment for Field Actinic Keratoses","Efficacy of Topical 5-FUvs Calcipotriol As PDT Pre-treatment for Field Actinic Keratoses","Inclusion Criteria:\n\n* Adult (\\>18 years old)\n* Field actinic keratoses on scalp\n* Generally good health\n\nExclusion Criteria:\n\n* Immunosuppression\n* Unable to provide consent\n* Abnormal photosensitivity\n* Contact allergy to metvix \u002F 5-FU \u002F calcipotriol \u002F topical corticosteroids\n* Pregnancy or breastfeeding","18 Years",{"count":49,"type":19},50,"INTERVENTIONAL",[52],"NA","The purpose of this study is to compare two different creams (5-fluorouracil, known as Efudix, and calcipotriol, known as Dovonex) to see which one works better when used before Photodynamic Therapy (PDT) to treat sun-damaged skin on the scalp (called actinic keratoses).\n\nPDT is often used on its own to treat these spots, but it doesn't always remove them completely. Using Efudix or Dovonex before PDT might improve the results, but we don't yet know which is better.\n\nThe main questions are -\n\n1. Is efudix or dovonex better at treating actinic keratoses when used prior to PDT\n2. Is efudix or dovonex more tolerable for patients?\n\nParticipants will be randomised to treat their scalp with efudix or dovonex for seven days prior to their first PDT treatment. They will be reviewed on day 7, prior to starting PDT, and again a week later when they present for their second PDT treatment.\n\nDuring follow up, patients will be reviewed at 28 days, 3, 6, 9, and 12 months after treatment.\n\nAt each of these visits, the number of actinic keratoses will be counted, graded, mapped and photographed to allow assessment of improvement before and after treatment.",[55,56],"Actinic Keratosis of Face and Scalp","Actinic Keratoses",[58,59,60,61,62,63],"efudix","dovonex","5-fluorouracil","calcipotriol","actinic keratosis","actinic keratoses","NOT_YET_RECRUITING","2024-11-10",{"date":67,"type":31},"2024-11-12",{"date":69,"type":19},"2025-01",{"date":71,"type":19},"2026-01",{"name":37,"class":38},""]