[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"St. Boniface Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":150},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,73,96],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100606133","tailoring-post-discharge---remote-education-and-access-for-cardiac-health-100606133",false,"NCT07171580","Tailoring Post Discharge - Remote Education and Access for Cardiac Health","TPD-REACH: Tailoring Post Discharge - Remote Education and Access for Cardiac Health","TPD-REACH","Inclusion Criteria:\n\n\\>18 years old, type 1 myocardial infarction27, resident of Manitoba\n\nExclusion Criteria:\n\nPatients unable to consent or fully participate in the study due to:\n\n1. Technology barriers\n\n   1. Lack of digital device, internet access or data\n   2. Discomfort with using technology\n2. Communication or language barriers preventing participation\n3. Cognitive or mental health limiting informed consent or participation\n\n   1. Dementia or cognitive impairment\n   2. Active or severe psychosis or other significant mental health conditions c. Active substance abuse\n4. High-risk ACS where patients require more frequent or in person visits a. Cardiac:\n\n   i. Coronary\n   * Unrevascularizedleftmainormultivessellargeepicardialcoronary artery disease (\\>2.5mm)\n   * Coronary artery bypass surgery (CABG) during index hospitalization ii. Arrhythmias\n   * Cardiac arrest during index event\u002Fhospitalization (ventricular tachycardia (VT)\u002Fventricular fibrillation (VF), pulseless electrical activity (PEA)) iii. Cardiomyopathy\n   * Left ventricular ejection fraction (LVEF) \\\u003C35% (most recent EF assessment)\n   * Cardiogenic shock requiring pressors\u002Finotropes for more than 24 hours\n   * Requiring intubation\u002Fpositive pressure ventilation\u002Fhi-flow oxygen for more than 24 hours\n   * Switchedfromintravenous(IV)tooral(PO)loopdiureticwithinlast 48 hours\n   * Change in PO loop diuretic dose within last 48 homes (home re- start of 80mg or less is allowed)\n   * B-type natriuretic peptide (BNP) did not reduce by 30% iv. Cardiac Care Unit (CCU)\u002FIntensive Care Unit (ICU) o Any CCU\u002FICU stay for more than 24 hours b. Medical: i. any condition with prognosis less than 1 year or a high LACE (Length of stay, Acuity of admission, Comorbidities, Emergency department use) score (\\>15)28 ii. any medical comorbidity requiring in-person assessment within 2 weeks TPD-REACH PROTOCOL v3 29Aug2025 8 of 17 TPD-REACH: Remote Education and Access for Cardiac Health iii. transition to an alternative living arrangement\u002Fcompromised independent living iv. need medication adjustment or investigation within 2 weeks c. Social: i. severe financial strain ii. no fixed address or housing instability iii. severe food insecurity iv. significant hearing or vision impairment v. poor health literacy While we aim to promote health equity, patients facing these challenges need more support than this project can offer and should be connected to appropriate services before discharge.\n5. Non-atherosclerotic causes of ACS (spontaneous coronary artery dissection, stress- induced cardiomyopathy, myocarditis) as the education and treatment is different\n6. Any additional factor preventing full participation in the study","ALL","18 Years",{"count":20,"type":21},300,"ESTIMATED","INTERVENTIONAL",[24],"NA","Heart attacks are one of the top causes of death in Canada, with over 2,100 cases treated each year in Manitoba. Even though hospital care has improved, the period after going home is still risky. Many patients feel anxious and unsure about their recovery, and without enough support, they often end up back in the emergency department (ED). This is an even bigger challenge for people in rural areas, where getting follow-up care can be much harder. Filling these gaps is important to help patients get better and to reduce stress on the healthcare system.\n\nIn a previous study, the investigators found that extra support made a big difference: only 8% of participants using a digital health tool returned to the ED within 30 days, compared to 22% of participants without it. Now, the investigators want to expand this study across Manitoba to see if digital health tools can help more people recover safely at home. The investigators will compare two types of follow-up care: education only versus education with extra support (like symptom tracking and virtual appointments). The investigators will look at how this affects hospital visits, mental well-being, and healthcare costs. The goal is to create a better support system for people after a heart attack, leading to healthier recoveries, less strain on hospitals, and better care for Manitobans - no matter where they live.",[27,28],"Acute Coronary Syndrome","Myocardial Infarction (MI)",[30,31,32,33,34],"Percutaneous Coronary Intervention","Education","Support","Digital Health Tool","Remote Home Monitoring","NOT_YET_RECRUITING","2025-09-08",{"date":38,"type":39},"2025-09-12","ACTUAL",{"date":41,"type":21},"2025-12-01",{"date":43,"type":21},"2027-04-30",{"name":45,"class":46},"St. Boniface Hospital","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100553823","effect-of-flax-in-yogurt-on-blood-cyanide-levels-100553823","NCT06491095","Effect of Flax in Yogurt on Blood Cyanide Levels","A Randomized, Controlled, Cross-over Trial Examining the Effect of Flaxseed on Blood Cyanide Levels in Healthy Adults","Inclusion Criteria:\n\n1. Generally healthy adult, 18 years or older;\n2. Willing to provide informed consent;\n3. Willing\u002Fable to comply with the requirements of the study.\n\nExclusion Criteria:\n\n1. Pregnant or lactating;\n2. Medical history of disease that is currently under treatment;\n3. Active treatment for any type of cancer within 1 year prior to study start;\n4. Presence of a gastrointestinal disorder, daily use of any stomach acid-lowering medications or laxatives (including fibre supplements) within the past month or antibiotic use within the past 6 weeks;\n5. Plasma concentration of vitamin B12 \\\u003C 148 pmol\u002FL;\n6. Complete blood count outside normal range;\n7. Medical history of liver disease or liver dysfunction (defined as plasma AST or ALT ≥3 times the upper limit of normal (ULN));\n8. Fasting blood glucose ≥6.1 mmol\u002FL and\u002For HbA1c ≥6.0%;\n9. Fasting plasma total cholesterol \\>7.8 mmol\u002FL;\n10. Fasting plasma HDL \\\u003C0.9 mmol\u002FL;\n11. Fasting plasma LDL \\>5.0 mmol\u002FL;\n12. Fasting plasma triglycerides \\>2.3 mmol\u002FL;\n13. Systolic blood pressure \\>140 mmHg or diastolic blood pressure \\>90 mmHg;\n14. Major surgery within the last 3 months;\n15. Smoking, use of tobacco, vape or cannabis (within the last week);\n16. Allergies to flaxseed or yogurt;\n17. Aversion or unwillingness to eat study foods;\n18. Participation in another clinical trial, current or in the past 4 weeks",true,{"count":57,"type":21},12,[24],"A randomized, controlled, cross-over post-prandial trial in healthy human volunteers will be conducted at the IH Asper Institute to determine the effect whole ground flaxseed, roasted then ground whole flaxseed, whole intact flaxseed and flaxseed hulls mixed into yogurt on blood cyanide levels.",[61],"Healthy",[63,64],"Flax","Blood Cyanide","2024-11-26",{"date":67,"type":39},"2024-12-02",{"date":69,"type":21},"2025-01-16",{"date":71,"type":21},"2026-03-28",{"name":45,"class":46},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":55,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":47},"100446086","survey-assessing-how-consumers-adapt-their-diet-in-response-to-health-claim-messaging-100446086","NCT05088863","Survey Assessing How Consumers Adapt Their Diet in Response to Health Claim Messaging","Inclusion Criteria:\n\n1. Man or woman, age ≥18 years;\n2. Willing to provide informed consent;\n3. Willing\u002Fable to comply with the requirements of the study;\n4. Have a mailing address in the Winnipeg census metropolitan area (City of Winnipeg and the municipalities of West St. Paul, East St. Paul, Headingley, Macdonald, Richot, Tache, Springfield, Rosser, St. Francois Xavier and St. Clements)4.\n\nExclusion Criteria:\n\n1. Allergy, aversion or unwillingness to eat whole ground flaxseed;\n2. Consuming ≥40g whole ground flaxseed\u002Fday;\n3. A family member within the same household is participating or has participated in this study;\n4. Currently participating in a food trial or dietary program that does not allow change in food choice.\n5. Pregnant or lactating",{"count":80,"type":21},384,[24],"A survey designed to examine how consumers adapt their diet in response to health claim messaging.",[84],"Health Claim Implementation",[86,87],"health claim","flax","RECRUITING",{"date":90,"type":39},"2024-11-29",{"date":92,"type":39},"2022-03-03",{"date":94,"type":21},"2025-11",{"name":45,"class":46},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":102,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":104,"minAge":105,"maxAge":4,"enrollmentInfo":106,"targetDuration":108,"studyType":109,"phases":4,"briefSummary":110,"conditions":111,"keywords":115,"overallStatus":88,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":47},"100357753","womens-advanced-risk-assessment-in-manitoba-100357753","NCT03938155","Women's Advanced Risk-assessment in Manitoba","Women's Advanced Risk-assessment in Manitoba (WARM) Hearts - Examining Cardiovascular Disease Risk in Middle Aged and Older Women","WARM","Inclusion Criteria:\n\n* women aged 55 and older\n* possess a Manitoba Personal Health Information Number\n\nExclusion Criteria:\n\nPrevious hospitalization or treatment for:\n\n* Ischemic heart disease\n* Acute myocardial infarction\n* Stroke\u002FTransient ischemic attack\n* Percutaneous coronary intervention\n* Coronary artery bypass surgery\n* Congestive heart failure\n* Peripheral artery disease\n* Congenital heart defects\n* Arrhythmia\n\nAdditional exclusion:\n\n* Medical advice against physical activity\n* Previous participant in the Assessment of Large and Small Artery Elasticity for the Early Detection of Cardiovascular Disease (NCT02863211)","FEMALE","55 Years",{"count":107,"type":21},1000,"5 Years","OBSERVATIONAL","The main objective of this study is to test the ability of novel cardiovascular disease (CVD) prognostic tools to identify women at risk for future CVD. We plan to establish a cardiovascular health screening program at the St. Boniface Hospital and to test the efficacy of these tests for predicting adverse cardiovascular outcomes amongst a cohort of 1000 Manitoban women aged 55 years and older in the 5-year period after screening.\n\nA second purpose of this project is to identify novel CVD biomarkers that may indicate a person is at risk for cardiovascular disease. Therefore, we plan to ask participants for permission to collect and store a sample of both their blood and stool for future research.",[112,113,114],"Cardiovascular Disease (CVD)","Cardiovascular Risk Factor","Vascular Stiffness",[116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141],"female","humans","aged","cardiovascular system","cardiovascular diseases","cardiovascular diseases\u002Fepidemiology","early diagnosis","frailty","frailty elderly","prospective studies","Manitoba\u002Fepidemiology","gastrointestinal microbiome","cohort studies","cause of death","risk assessment","biomarkers","risk factors","pulse wave analysis","accelerometry","exercise","physical fitness","gender","sex","women","early detection","screening program","2021-01-25",{"date":144,"type":39},"2021-01-28",{"date":146,"type":39},"2019-10-01",{"date":148,"type":21},"2026-10",{"name":45,"class":46},""]