[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"St. Mary's University, Twickenham\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":146},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,64,95,123],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100629515","effects-of-short-term-acute-creatine-supplementation-on-power-speed-and-muscular-strengths-in-young-football-players-100629515",false,"NCT07475676","Effects of Short-term Acute Creatine Supplementation on Power, Speed and Muscular Strengths in Young Football Players","The inclusion criteria require individuals:\n\n* Male or female between the age of 18-45\n* Trained individuals currently playing at a semi-professional (regional) level currently training and competing no more than three times a week\n* Free of long-term injuries for the last six months\n* Not supplementing creatine within the last 3 months.\n* Able to swallow pills\n* No medical conditions\n\nExclusion Criteria:\n\n* Individuals will be excluded from participation if they are under the age of 18 or over the age of 45\n* Not currently playing football at a semi-professional (regional) level.\n* Train and\u002For compete more than three times per week\n* Have any current injury or have experienced a long-term injury within the previous six months that may affect performance or increase the risk of injury during testing.\n* Individuals who have supplemented with creatine within the last three months, - Any medical condition will not be eligible to take part in the study.","ALL","18 Years","45 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","Creatine has been widely studies within the strength and conditioning background and has been seen to show positive effects on performance assess the effects of creatine on sports requiring a range of different fitness components to be successful such as football. Previous research has suggested benefits of creatine supplementation such as increasing PCr (phosphocreatine) stores to aid ATP (adenosine triphosphate) production, increasing muscle water retention resulting in enhanced protein synthesis, reduced muscle damage and anti-inflammation. Identifying supplements that are scientifically proved to aid performance can help optimise training and develop physical ability of athletes to enhance performance.",[26],"Performance Enhancement","NOT_YET_RECRUITING","2026-03-11",{"date":30,"type":31},"2026-03-16","ACTUAL",{"date":33,"type":20},"2026-03-01",{"date":35,"type":20},"2026-04-13",{"name":37,"class":38},"St. Mary's University, Twickenham","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":15,"minAge":16,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":4},"100626743","long-term-omega-3-and-omega-3-index-8-effects-on-physiological-recovery-100626743","NCT07439601","Long-Term Omega-3 and Omega-3 Index >8%: Effects on Physiological Recovery","The Impact of Long-term Omega-3 Supplementation and an Omega-3 Index Above 8% on Physiological Recovery Following Exercise-Induced Muscle Damage","IMPROVE-8","Inclusion Criteria:\n\n* An Omega-3 index of ≤ 6%\n* Age 18-50 years\n* Sub-elite to elite athletes from local sports teams (e.g. cycling, triathlon)\n* Male and female\n\nExclusion Criteria:\n\n* inflammatory diseases, injuries that prevent them exercising.",true,"50 Years",{"count":51,"type":20},46,[23],"The Omega-3 Index measures how much of the Omega-3 fats EPA and DHA are built into red blood cell membranes. These fats are essential for health, but the body cannot make enough of them, so they must come from foods like oily fish or from supplements. The Index reflects long-term Omega-3 intake and is considered optimal at 8% or higher. Levels below this range have been linked with poorer cardiovascular health (Harris \\& Von Schacky, 2004).\n\n. For athletes, Omega-3 research suggests they can help reduce inflammation, ease muscle soreness, and support immune function. Despite this, many elite athletes appear to have Omega-3 Index values around 4-5%, well below the recommended level of 8%.\n\nTherefore, the aim of this study is to investigate whether increasing the Omega-3 index has any recovery benefits post a bout of downhill running in athletes. Downhill running is commonly used as way to cause exercise-induced muscle damage and study recovery. The Omega-3 index will be increased with a daily fish oil supplement.",[55],"Focus on Omega 3 Index on Recovery","2026-02-23",{"date":58,"type":31},"2026-02-27",{"date":60,"type":20},"2026-02-28",{"date":62,"type":20},"2028-12-30",{"name":37,"class":38},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":4,"eligibilityCriteria":69,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":70,"targetDuration":4,"studyType":72,"phases":4,"briefSummary":73,"conditions":74,"keywords":77,"overallStatus":86,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":39},"100608864","observational-case-series-of-patients-with-parkinsons-disease-pd-attending-a-complementary-medicine-neuro-degenerative-disease-ndd-clinic-100608864","NCT07207096","Observational Case Series of Patients With Parkinson's Disease (PD) Attending a Complementary Medicine Neuro-degenerative Disease (NDD) Clinic.","Inclusion Criteria: A diagnosis of Parkinson's Disease (self-reported), and Parkinsonism from any causes (patients may have co-existing other health conditions)\n\nExclusion Criteria: Patients requiring acute medical assessment and management, (as this is beyond the scope of this clinic service) Patients with any other NDD condition Patients without a diagnosis of PD\u002FParkinsonism. E.g. those at risk of PD such as through a family history (patients in this category may receive treatment at the clinic but are not included in the Observational Case series.",{"count":71,"type":20},100,"OBSERVATIONAL","When the charity Homeopathy UK launched a new London based charitable clinic for Neurodegenerative Diseases (NDD), including Parkinson's Disease (PD), it was considered important to document patient's experiences of a high-quality complementary medicine clinic, to enable a greater understanding of the role of complementary medicine for PD.\n\nRoutine clinical data, including a couple of questionnaires, is collected from consecutive patients with PD seen in the NDD clinic. Treatments provided are complementary to patients' usual medical treatment, and include homeopathy, herbalism, hypnosis, and healing. Patients may also be provided with self-help advice for lifestyle changes, mindfulness or meditation techniques, and dietary advice, as indicated for complementary therapy management of their condition. Consultations take place approximately every 3 months and patients complete questionnaires at the time of each consultation.",[75,76],"Parkinson Disease","Parkinsonism",[78,79,80,81,82,83,84,85,75],"homeopathy","herbalism","hypnosis","healing","complementary medicine","lifestyle","self-help","mindfulness","RECRUITING","2025-09-26",{"date":89,"type":31},"2025-10-03",{"date":91,"type":31},"2025-09-19",{"date":93,"type":20},"2027-08-31",{"name":37,"class":38},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":48,"sex":102,"minAge":16,"maxAge":17,"enrollmentInfo":103,"targetDuration":4,"studyType":21,"phases":105,"briefSummary":106,"conditions":107,"keywords":110,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":115,"lastUpdatePostDateStruct":116,"startDateStruct":118,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100602875","the-effects-of-caffeine-on-exercise-physiology-and-time-trial-performance-in-a-hot-environment-100602875","NCT07129200","The Effects of Caffeine on Exercise Physiology and Time-trial Performance in a Hot Environment","The Effects of Caffeine Supplementation on Exercise Physiology and Time-trial Performance in a Hot Environment","Inclusion Criteria:\n\n* Healthy trained runners\n\nExclusion Criteria:\n\n\\-","MALE",{"count":104,"type":20},15,[23],"Maintaining a stable core temperature is vital for physiological function; yet, exercise in heat can be problematic, and there is risk of exertional heat-related illness (Flouris \\& Schlader, 2015; Leyk et al., 2019; Périard et al., 2021; Tyler et al., 2016; Veltmeijer et al., 2015). While aerobic fitness improves heat tolerance (Alhadad et al., 2019), strategies like acclimation and pre-cooling also mitigate heat stress (Casadio et al., 2016; Lorenzo et al., 2010; Ross et al., 2013; Siegel et al., 2010). Caffeine, an ergogenic aid (Del Corso et al., 2011; John et al., 2024), is known to enhance performance via adenosine antagonism and increased catecholamines in normothermic environments (Fredholm et al., 1999; Graham \\& Spriet, 1991). However, effects in heat are inconsistent (Ganio et al., 2009; Zhang et al., 2014), possibly due to caffeine reducing the ability to thermoregulate effectively. Therefore, the aim of this study is to investigate the effects of a moderate dose of caffeine (5 mg\u002Fkg) on thermoregulation during a 30-minute running time trial in 35°C heat.",[108,109],"Caffeine","Thermoregulation",[111,112,113,114],"caffeine","thermoregulation","time trial","exercise physiology","2025-08-12",{"date":117,"type":31},"2025-08-19",{"date":119,"type":20},"2025-08-22",{"date":121,"type":20},"2026-06-30",{"name":37,"class":38},{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":48,"sex":102,"minAge":16,"maxAge":129,"enrollmentInfo":130,"targetDuration":4,"studyType":21,"phases":132,"briefSummary":133,"conditions":134,"keywords":135,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":4},"100587963","the-repeatability-of-the-effect-of-caffeine-supplementation-on-submaximal-physiological-responses-and-cycling-time-trial-performance-100587963","NCT06935214","The Repeatability of the Effect of Caffeine Supplementation on Submaximal Physiological Responses and Cycling Time Trial Performance","Inclusion Criteria:\n\n* To be considered for inclusion in the study, participants must be regular cyclists, between 18 and 35 years of age, capable of completing a 20 km cycling time trial at a minimum speed of 30 km\u002Fh (arbitrary inclusion criteria to ensure a sufficient standard of athlete).\n\nExclusion Criteria:\n\n\\-","35 Years",{"count":131,"type":20},12,[23],"Recently, Grgic (2018) discussed the concept of responders and non-responders to caffeine supplementation highlighting the importance of the repeatability of results. However, the number of studies that have investigated this idea by repeating the same time-trial performance test multiple times with the same caffeine dose is sparse (Astorino et al., 2012; Del Coso et al., 2019). Furthermore, studies have shown that differences in the CYP1A2 genotype may account for some of the variation in time-trial performance (Guest et al., 2018). Thus, the current study aims to identify whether the effects of moderate caffeine supplementation (5 mg\u002Fkg) on time-trial performance are repeatable to aid the identification of responders and non-responders. Additionally, the study aims to determine if the CYP1A2 genotype may explain any of the variability in time-trial performance in trained male cyclists.",[108],[111,136,137,113],"genetics","cycling","2025-04-11",{"date":140,"type":31},"2025-04-20",{"date":142,"type":20},"2025-05-01",{"date":144,"type":20},"2025-12-31",{"name":37,"class":38},""]