[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"State Scientific Centre of Coloproctology, Russian Federation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":129},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,48,74,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100613566","combined-method-of-surgical-treatment-of-anal-fissure-100613566",false,"NCT07268261","Combined Method of Surgical Treatment of Anal Fissure","Inclusion Criteria:\n\n* • Patients with chronic anal fissure with spasm of anal sphincter\n\nExclusion Criteria:\n\n* • Inflammatory diseases of the colon\n\n  * Pectenosis\n  * Previous surgical interventions on the anal canal\n  * IV grade internal and external hemorrhoids\n  * Rectal fistula\n  * Severe somatic diseases at the decompensation stage\n  * Pregnancy and lactation\n  * Anal sphincter insufficiency\n  * Chronic paraproctitis\n  * Individual intolerance and hypersensitivity to botulinum toxin\n  * Myasthenia gravis and myasthenic syndromes\n  * History of allergic reaction to anticoagulants.\n  * Blood diseases (thrombocytopenia, splenomegaly, etc.)","ALL","18 Years","70 Years",{"count":19,"type":20},122,"ESTIMATED","INTERVENTIONAL",[23],"NA","The purpose of this study is to improve treatment outcomes for patients with chronic anal fissure.",[26],"Chronic Anal Fissure",[28,29,30,31,32,33,34],"Fissure in Ano","Anal fissure","botulinum toxin A","Chronic anal pain","Fecal incontinence","Spasm of the internal sphincter","Anal sphincter insufficiency","RECRUITING","2025-12-03",{"date":38,"type":39},"2025-12-05","ACTUAL",{"date":41,"type":39},"2023-09-01",{"date":43,"type":20},"2026-09-01",{"name":45,"class":46},"State Scientific Centre of Coloproctology, Russian Federation","OTHER_GOV",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":21,"phases":59,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":47},"100552175","effectiveness-of-artificial-intelligence---assisted-colonoscopy-in-colorectal-neoplasms-100552175","NCT06469671","Effectiveness of Artificial Intelligence - Assisted Colonoscopy in Colorectal Neoplasms","Artificial Intelligence - Assisted Colonoscopy in Diagnosis of Colorectal Neoplasms: Russian Multicenter Randomised Open - Label Trial","ArtInCol","Inclusion Criteria:\n\n* Screening coloscopy is needed\n\nExclusion Criteria:\n\n* Indications for colonoscopy\n* Previously detected colorectal neoplasms\n* Previously performed colorectal surgery\n* Colorectal cancer\n* Inflammatory bowel disease","90 Years",{"count":58,"type":20},1000,[23],"The primary goal of this study is to estimate the effectiveness of a medical decision support system based on artificial intelligence in the endoscopic diagnosis of benign tumors.\n\nResearchers will compare Adenoma detection rate between \"artificial intelligence - assisted colonoscopy\" and \"conventional colonoscopy\" groups to evaluate the clinical effectiveness of artificial intelligence model.",[62,63,64],"Colonic Neoplasms","Colonic Polyp","Diagnosis","NOT_YET_RECRUITING","2024-06-17",{"date":68,"type":39},"2024-06-21",{"date":70,"type":20},"2024-07",{"date":72,"type":20},"2024-12",{"name":45,"class":46},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":81,"targetDuration":83,"studyType":84,"phases":4,"briefSummary":85,"conditions":86,"keywords":91,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":47},"100477346","prospective-multicenter-registry-study-to-assess-the-frequency-of-lynch-syndrome-among-patients-with-colorectal-cancer-100477346","NCT05495776","Prospective Multicenter Registry Study to Assess the Frequency of Lynch Syndrome Among Patients With Colorectal Cancer","MSIRus22","Inclusion Criteria:\n\n* Provision of written informed consent;\n* Patients with histologically verified colon adenocarcinoma or patients with histologically verified synchronous neoplasms who have not previously received treatment for a second tumor;\n* Age ≥ 18 years;\n* Absence of antitumor treatment for a real tumor (it is allowed to include patients who have a history of antitumor treatment for other malignant tumors, if the period after treatment is more than 12 months).\n* The ability of the patient, according to the Researcher, to fulfill the requirements of the Protocol;\n\nExclusion Criteria:\n\n\\- Patients receiving chemotherapy or radiotherapy for colon cancer at the time of screening",{"count":82,"type":20},2500,"5 Years","OBSERVATIONAL","Prospective multicenter registry study to assess the frequency of Lynch syndrome among patients with colorectal cancer in Russia",[87,88,89,90],"Colorectal Cancer","Lynch Syndrome","Hereditary Colorectal Cancer","MSI",[87,88,89,90,92],"Frequency","2022-10-24",{"date":95,"type":39},"2022-10-25",{"date":97,"type":39},"2022-08-01",{"date":99,"type":20},"2028-12-31",{"name":45,"class":46},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":112,"conditions":113,"keywords":114,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":128},"100351378","phase-4-complex-treatment-of-a-chronic-anal-fissure-100351378","NCT03855046","Complex Treatment of a Chronic Anal Fissure","A Comparative Efficacy and Safety Study of Lateral Subcutaneous Sphincterotomy and Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure","Inclusion Criteria:\n\n* Patients with chronic anal fissure\n\nExclusion Criteria:\n\n* Inflammatory diseases of the colon\n* Pectenosis\n* Previous surgical interventions on the anal canal\n* IV grade internal and external hemorrhoids\n* Rectal fistula\n* Severe somatic diseases at the decompensation stage\n* Pregnancy and lactation\n* Individual intolerance and hypersensitivity to botulinum toxin\n* Myasthenia gravis and myasthenia-like syndromes\n* Anal sphincter insufficiency",{"count":109,"type":20},340,[111],"PHASE4","This study is aimed at studying the efficacy and safety of treating chronic anal fissure with botulinum toxin versus lateral subcutaneous sphincterotomy.",[28],[115,29,116,30,117,118,31,32,33,34,119],"Internal sphincterotomy","Chronic anal fissure","proctologic diseases","surgical treatment","randomized","2022-01-26",{"date":122,"type":39},"2022-01-27",{"date":124,"type":39},"2019-09-01",{"date":126,"type":20},"2022-11-01",{"name":45,"class":46},7,""]