[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"State University of Londrina\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100633064","exercise-training-in-women-with-metastatic-breast-cancer-100633064",false,"NCT07521826","Exercise Training in Women With Metastatic Breast Cancer","Randomized Controlled Trial of a Combined Exercise Training Program on Physical Function and Quality of Life in Women With Metastatic Breast Cancer","FITCAN","Inclusion Criteria:\n\n* Women aged ≥ 18 years;\n* Confirmed diagnosis of stage IV (metastatic) breast cancer;\n* Currently undergoing medical treatment;\n* Willingness and functional independence to participate in the exercise program;\n* Medical clearance to engage in structured physical exercise.\n\nExclusion Criteria:\n\n* Presence of unstable bone metastases.\n* Untreated or symptomatic brain metastases;\n* Evidence of severe cardiovascular disease identified by electrocardiogram (ECG);\n* Severe active infection;\n* Uncontrolled severe respiratory insufficiency or dependence on supplemental oxygen at rest or during exercise;\n* Uncontrolled severe pain;\n* Any other medical condition contraindicating participation in physical exercise;\n* Conditions that impair adherence to study procedures or the ability to provide informed consent;\n* Pregnancy.","FEMALE","18 Years",{"count":20,"type":21},78,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary objective of the study is to evaluate the effects of exercise on physical function, physical fitness, and body composition, with the main components including muscular strength, cardiorespiratory fitness, muscle mass, fat mass, and fat-free mass. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (HRQoL), cancer-related fatigue, and sleep quality. Additionally, the feasibility and safety of the exercise program will be assessed.",[27,28],"Cancer","Metastases",[30,31,32,33,34],"Low muscle strength","muscle loss","loss of physical function","cardiorespiratory fitness","multimodal exercise","NOT_YET_RECRUITING","2026-04-07",{"date":38,"type":39},"2026-04-13","ACTUAL",{"date":41,"type":21},"2026-04",{"date":43,"type":21},"2028-12",{"name":45,"class":46},"State University of Londrina","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":70,"locationsCount":47},"100631308","exercise-for-the-treatment-of-cancer-related-sarcopenia-100631308","NCT07498985","Exercise for the Treatment of Cancer-Related Sarcopenia","Exercise for the Treatment of Cancer-Related Sarcopenia: a Randomised Controlled Trial.","HERA","Inclusion Criteria:\n\n* \\> 18 years old women with a confirmed diagnosis of breast or gynecological cancer.\n* Any level of sarcopenia (pre-sarcopenia, sarcopenia, or severe sarcopenia).\n* Patients must have completed their primary treatment regimen (surgery, chemotherapy, and\u002For radiotherapy) for at least 2 weeks and up to 2 years before enrolment.\n* have received the medical consent to be engaged in physical exercise programs.\n\nExclusion Criteria:\n\n* The presence of one or more comorbidities that could potentially interfere with attendance or test results (e.g., other cancers or acute or chronic renal failure);\n* Already in exercise programs comparable to the HERA program;\n* Evidence of severe cardiovascular disease as a result of an electrocardiogram.",{"count":20,"type":21},[24],"Our primary objective is to assess the effects of exercise on cancer-related sarcopenia and its hallmarks, including muscle strength, muscle mass, and physical performance. The secondary objectives are to examine exercise adherence and the effects of exercise on health-related quality of life (QoL), cancer-related fatigue, and sleep quality. Additionally, we will explore the effects of exercise on bone and fat mass as secondary outcomes.",[27,60],"Sarcopenia",[31,62,63],"Frail","Resistance Training","2026-03-24",{"date":66,"type":39},"2026-03-27",{"date":68,"type":21},"2026-04-01",{"date":43,"type":21},{"name":45,"class":46},""]