[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":501},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,48,78,103,130,151,170,194,228,252,275,298,317,338,363,382,403,427,455,482],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100644211","immediate-effects-of-plantar-fascia-release-combined-with-foot-exercises-on-fms-subscores-in-young-adults-with-pes-planus-100644211",false,"NCT07664332","Immediate Effects of Plantar Fascia Release Combined With Foot Exercises on FMS Subscores in Young Adults With Pes Planus","Immediate Effects of Plantar Fascia Release Combined With Foot Exercises on Functional Movement Screen Subscores in Young Adults With Pes Planus: A Randomized Crossover Study","FMS-PP","Inclusion Criteria:\n\n* Being between 18 and 35 years of age\n* Voluntarily agreeing to participate in the study and providing written informed consent\n* Having pes planus according to the Navicular Drop Test result\n* Having the cognitive ability to understand and perform the Functional Movement Screen (FMS) test instructions\n* Being classified as sufficiently physically active according to the International Physical Activity Questionnaire (IPAQ), defined as at least 1,500 MET-min\u002Fweek of vigorous-intensity activity or at least 3,000 MET-min\u002Fweek of moderate-intensity activity\n* Having no history of lower-extremity surgery within the previous 6 months\n* Having no history of lower-extremity injury or disability within the previous 6 months\n* Agreeing to complete the study protocol over two days\n\nExclusion Criteria:\n\n* Having a history of ankle sprain, particularly recurrent ankle sprains\n* Presence of hallux valgus deformity\n* Presence of hammer toe deformity\n* Presence of generalized ligamentous laxity\n* Having a history of systemic disease, such as rheumatic, neurological, or metabolic disorders\n* Presence of ongoing lower-extremity pain\n* Having any orthopedic or neurological condition that may prevent the safe performance of the Functional Movement Screen tests","ALL","18 Years","35 Years",{"count":21,"type":22},29,"ESTIMATED","INTERVENTIONAL",[25],"NA","This randomized crossover clinical study aims to investigate the immediate effects of plantar fascia release combined with foot exercises on Functional Movement Screen sub-scores in physically active young adults with pes planus.\n\nParticipants aged 18-35 years with pes planus, determined by the Navicular Drop Test, will complete two different intervention protocols in a randomized order. Protocol A will include foot-core exercises combined with plantar fascia stretching. Protocol B will include the same foot-core exercises and plantar fascia stretching, with the addition of plantar fascia myofascial release. Each participant will receive both interventions on separate sessions, with a 24-hour washout period between sessions.\n\nFunctional movement quality will be assessed using two Functional Movement Screen subtests: Deep Squat and Hurdle Step. These tests will be performed before and after each intervention session to evaluate acute changes in movement performance.\n\nThe main hypothesis of the study is that plantar fascia myofascial release combined with foot-core exercises and plantar fascia stretching will produce greater immediate improvements in Functional Movement Screen Deep Squat and Hurdle Step scores compared with foot-core exercises and plantar fascia stretching alone.",[28,29],"Pes Planus","FMS",[28,31,32,33,34],"Functional Movement Screen","Plantar Facia","Deep squat","Hurdle Step","NOT_YET_RECRUITING","2026-06-24",{"date":38,"type":39},"2026-06-29","ACTUAL",{"date":41,"type":22},"2026-07-18",{"date":43,"type":22},"2026-08-14",{"name":45,"class":46},"Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":66,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":4},"100642999","investigation-of-pain-modulation-phenotypes-in-female-patients-with-fibromyalgia-100642999","NCT07640607","Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia","Inclusion Criteria:\n\n1. Having received a diagnosis of fibromyalgia according to the 2016 ACR diagnostic criteria\n2. Female patients aged 18-65\n3. Being literate\n4. Having signed the informed consent form upon agreeing to participate in the study\n\nExclusion Criteria:\n\n1. Being under 18 or over 65 years of age\n2. Having any condition that may lower the pain threshold or cause chronic pain (Rheumatoid Arthritis, Ankylosing Spondylitis, systemic inflammatory diseases, malignancies, etc.)\n3. Any neurological condition (stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies…)\n4. Peripheral artery disease\n5. Severe cardiopulmonary insufficiency (stage 3-4)\n6. Uncontrolled systemic diseases such as hypertension and diabetes\n7. Presence of an active infection\n8. Pregnancy\n9. Presence of cognitive impairment, hearing loss, or communication difficulties that would prevent understanding of questionnaires and protocols","FEMALE","65 Years",{"count":57,"type":22},82,"OBSERVATIONAL","Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization. While both mechanisms have been independently associated with disease severity, their interrelationship remains unclear. This cross-sectional study aims to investigate whether central sensitization symptoms mediate the relationship between conditioned pain modulation and fibromyalgia impact.",[61,62,63,64,65],"Fibromyalgia (FM)","Quantitative Sensory Testing","Central Sensitization","PRESSURE PAIN THRESHOLD","Pain Perception",[67,68,69],"Fibromyalgia","Pain sensitization","Conditioned pain modulation","2026-06-05",{"date":72,"type":39},"2026-06-11",{"date":74,"type":22},"2026-06-01",{"date":76,"type":22},"2026-09-01",{"name":45,"class":46},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":85,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":86,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":47},"100642747","relationship-between-central-sensitization-and-clinical-features-in-plantar-fasciitis-100642747","NCT07640620","Relationship Between Central Sensitization and Clinical Features in Plantar Fasciitis","IInvestigation of the Relationship Between Central Sensitization and Clinical, Functional, and Ultrasonographic Parameters In Plantar Fasciitis","Plantar Fasciitis Group\n\n1. Inclusion criteria\n\n   * Be between the ages of 18-65\n   * Have unilateral heel pain that has been ongoing for at least 3 months, particularly worsening with the first few steps in the morning and increasing with weight-bearing activities throughout the day\n   * Have tenderness on palpation of the medial calcaneal tubercle\n   * Have read and signed the volunteer consent form (VCF)\n2. Exclusion criteria\n\n   * Being under 18 years old or over 65 years old\n   * Having a history of physical therapy, injection, radiation, or surgery targeting the plantar fascia within the last 6 months\n   * Calcaneus fracture, tumor, or cyst related to the plantar fascia\n   * Foot deformity (club foot, pes cavus, calcaneovalgus, etc.)\n   * Lumbosacral radiculopathy, tarsal tunnel syndrome, peripheral neuropathy\n   * Rheumatic diseases such as rheumatoid arthritis, ankylosing spondylitis, gout\n   * Foot and ankle osteoarthritis\n   * Presence of osteomyelitis or skin infection in the foot\n   * Systemic diseases such as kidney and liver failure, diabetes, peripheral arterial vascular disease\n\nHealthy Control\n\n1. Inclusion criteria\n\n   * Being completely healthy\n   * Being between the ages of 18 - 65\n   * Having read and signed the volunteer consent form (BGOF)\n2. Exclusion criteria\n\n   * Being under 18 or over 65 years old\n   * Having any acute or chronic illness\n   * Being illiterate and not giving consent to participate in the study",true,{"count":87,"type":22},128,"Plantar fasciitis is a common cause of heel pain and is traditionally considered a mechanical musculoskeletal disorder. Recent evidence suggests that central sensitization may also contribute to pain in individuals with plantar fasciitis. This study aims to investigate the relationships between neurophysiological variables (pressure pain threshold, central sensitization, and pain intensity), psychological factors (pain catastrophizing, kinesiophobia, anxiety, and depression), ultrasonographic findings (plantar fascia thickness), and functional outcomes (foot function and quality of life) in patients with plantar fasciitis.",[90],"Plantar Fasciitis",[92,93,94,95],"plantar fasciitis","central sensitization","pain pressure threshold","kinesiophobia","RECRUITING",{"date":72,"type":39},{"date":99,"type":39},"2026-04-07",{"date":101,"type":22},"2026-09-20",{"name":45,"class":46},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":111,"targetDuration":4,"studyType":23,"phases":113,"briefSummary":114,"conditions":115,"keywords":117,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":127,"leadSponsor":129,"locationsCount":47},"100640547","the-effect-of-nerve-blocks-on-analgesia-in-breast-cancer-surgery-100640547","NCT07601490","The Effect of Nerve Blocks on Analgesia in Breast Cancer Surgery","Comparison of Postoperative Analgesic Efficacy of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block in Modified Radical Mastectomy Surgery","breast surgery","Inclusion Criteria:\n\n* Female patients aged between 18 and 65 years\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Body Mass Index (BMI) \\\u003C35 kg\u002Fm²\n* Normal International Normalized Ratio (INR) value and platelet count\n* Normal liver and renal function tests\n* Patients scheduled for elective modified radical mastectomy surgery\n\nExclusion Criteria:\n\n* Bleeding diathesis\n* Allergy to local anesthetic agents\n* Suspected infection or inflammation at the planned block site\n* ASA physical status IV or higher\n* Long-term medication use due to chronic pain\n* Advanced hepatic or renal failure\n* Presence of severe pulmonary disease\n* Use of any opioid medication within 24 hours before surgery\n* Cognitive impairment\n* Patients undergoing revision surgery",{"count":112,"type":22},70,[25],"Postoperative pain following modified radical mastectomy remains a significant clinical concern and may adversely affect patient recovery, opioid consumption, and overall patient satisfaction. Ultrasound-guided regional anesthesia techniques have gained increasing importance as part of multimodal analgesia strategies in breast surgery. The serratus anterior plane (SAP) block is a commonly used interfascial plane block for postoperative analgesia in thoracic and breast procedures. Recently, the serratus posterior superior intercostal plane (SPSIP) block has emerged as a novel regional anesthesia technique with potentially wider thoracic dermatomal spread and effective analgesic properties.\n\nThis prospective randomized controlled study aims to compare the postoperative analgesic efficacy of the SPSIP block and SAP block in patients undergoing modified radical mastectomy under general anesthesia. Patients will be randomly allocated into two groups to receive either ultrasound-guided SPSIP block or SAP block preoperatively. Primary outcomes will include postoperative pain scores and opioid consumption within the first 24 hours after surgery. Secondary outcomes will include time to first analgesic request, rescue analgesic requirements, intraoperative hemodynamic parameters, postoperative nausea and vomiting, block-related complications, and patient satisfaction.\n\nThe study is designed to evaluate whether SPSIP block provides superior postoperative analgesia compared with SAP block in modified radical mastectomy surgery.",[116],"Breast Cancer Surgery Pain",[118,119,120,121],"modified radical mastectomy","Serratus Posterior Superior Intercostal Plane Block","Serratus Anterior Plane Block","Postoperative analgesia","2026-05-22",{"date":124,"type":39},"2026-05-27",{"date":126,"type":22},"2026-06-15",{"date":128,"type":22},"2026-10-16",{"name":45,"class":46},{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":137,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":138,"conditions":139,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":146,"completionDateStruct":148,"leadSponsor":150,"locationsCount":47},"100640028","assessment-of-venous-insufficiency-and-clinical-features-in-lipedema-100640028","NCT07603076","Assessment of Venous Insufficiency and Clinical Features in Lipedema","Evaluation of Venous Insufficiency and Its Association With Clinical Features in Patients With Lipedema: A Cross-Sectional Study","Inclusion Criteria:\n\n* Female participants aged 18 years or older\n* Clinically diagnosed lipedema according to established diagnostic criteria\n* Ability to provide written informed consent\n* Ability to complete clinical assessments and questionnaires\n\nExclusion Criteria:\n\n* History of lower extremity venous surgery or sclerotherapy\n* Known peripheral arterial disease\n* Secondary lymphedema or other causes of lower extremity edema\n* Active infection, cellulitis, or inflammatory disease affecting the lower extremities\n* Pregnancy or postpartum period\n* Neurological, rheumatological, or musculoskeletal disorders significantly affecting lower extremity function\n* Malignancy or severe systemic disease\n* Inability to undergo venous Doppler ultrasonography\n* Inability to understand or complete study assessments and questionnaires",{"count":57,"type":22},"Lipedema is a chronic adipose tissue disorder characterized by disproportionate fat accumulation, pain, tenderness, edema, and functional impairment. Venous symptoms such as heaviness, swelling, and discomfort are frequently reported in individuals with lipedema; however, the relationship between venous Doppler ultrasonography findings and lipedema-related clinical manifestations remains insufficiently investigated. This cross-sectional controlled study aims to evaluate venous insufficiency parameters in patients with lipedema using Doppler ultrasonography and to examine their associations with pain severity, lower extremity function, disease severity, and quality of life.",[140,141,142,143],"Lipedema","Venous Insufficiency","Venous Disease","Disability Physical","2026-05-17",{"date":122,"type":39},{"date":147,"type":22},"2026-05-20",{"date":149,"type":22},"2026-08-01",{"name":45,"class":46},{"id":152,"slug":153,"hasResults":11,"nctId":154,"briefTitle":155,"officialTitle":156,"acronym":4,"eligibilityCriteria":157,"healthyVolunteers":85,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":158,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":159,"conditions":160,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100628902","perioperative-hypothermia-and-sevoflurane-consumption-in-elderly-patients-100628902","NCT07467681","Perioperative Hypothermia and Sevoflurane Consumption in Elderly Patients","Perioperative Hypothermia and Sevoflurane Consumption in Elderly Patients Undergoing Hip Arthroplasty","Inclusion Criteria:\n\n* Age ≥ 65 years\n* Elective hip arthroplasty under general anesthesia\n* ASA physical status I-III\n\nExclusion Criteria:\n\n* Preoperative Mini-Cog score ≤ 2\n* Neurological or psychiatric disorders affecting cognitive function\n* Endocrine or metabolic disorders affecting thermoregulation\n* Excessive intraoperative blood loss\n* Emergency surgery",{"count":112,"type":22},"This prospective observational study aims to evaluate the association between perioperative hypothermia and sevoflurane consumption in elderly patients undergoing hip arthroplasty under general anesthesia. Patients aged 65 years and older will be included. Perioperative body temperature and anesthetic consumption will be recorded, and the relationship between hypothermia and anesthetic requirements will be analyzed. The findings may help clarify whether hypothermia influences anesthetic depth monitoring and anesthetic consumption in elderly surgical patients.",[161],"Perioperative Hypothermia","2026-03-08",{"date":164,"type":39},"2026-03-12",{"date":166,"type":22},"2026-03-20",{"date":168,"type":22},"2026-07-01",{"name":45,"class":46},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":11,"sex":17,"minAge":55,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":179,"conditions":180,"keywords":182,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":4},"100607685","the-importance-of-anesthesia-method-in-fragile-patients-100607685","NCT07191769","The Importance of Anesthesia Method in Fragile Patients","The Effect of the Selected Anaesthesia Method on Morbidity and Mortality in Frail Patients Scheduled for Transurethral Surgery","Inclusion Criteria:\n\n* Elderly patients aged 65 and over\n* ASA (American Society of Anaesthesiologists) physical condition classification I-III patients\n* meeting the criteria for frailty\n\nExclusion Criteria:\n\n* Non-elective emergency surgeries\n* Patients under 65 years of age\n* Patients classified as ASA Class IV\n* Patients unable to provide informed consent due to cognitive impairment\n* Patients who have previously undergone major neurological or cardiac surgery",{"count":178,"type":22},180,"The aim of this study is to comparatively evaluate the effects of different anaesthesia methods (spinal anaesthesia and general anaesthesia) administered to frail elderly patients scheduled for transurethral surgery (e.g. TUR-Prostate or TUR-Bladder) on postoperative morbidity and mortality rates.",[181],"Frail Elderly Syndrome",[183,184,185],"frail patient","general anaesthesia","regional anaesthesia","2025-09-23",{"date":188,"type":39},"2025-09-25",{"date":190,"type":22},"2025-10-01",{"date":192,"type":22},"2026-02",{"name":45,"class":46},{"id":195,"slug":196,"hasResults":11,"nctId":197,"briefTitle":198,"officialTitle":199,"acronym":4,"eligibilityCriteria":200,"healthyVolunteers":11,"sex":17,"minAge":201,"maxAge":4,"enrollmentInfo":202,"targetDuration":4,"studyType":23,"phases":204,"briefSummary":205,"conditions":206,"keywords":211,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":47},"100595041","the-insertion-of-i-gel-and-classic-lma-in-different-head-positions-in-elderly-patients-100595041","NCT07027293","The Insertion of I-gel and Classic LMA in Different Head Positions in Elderly Patients","Evaluation of the Insertion of I-gel and Classic LMA in Different Head Positions in Elderly Patients","Inclusion Criteria:\n\n* ASA classification I-III\n* Age over 75 years\n\nExclusion Criteria:\n\n* Known or anticipated difficult airway\n* Contraindications for the use of a supraglottic airway device\n* Patients scheduled for endotracheal intubation","75 Years",{"count":203,"type":22},120,[25],"This prospective, randomized, double-blind clinical study aims to evaluate the insertion success of two supraglottic airway devices, the classic Laryngeal Mask Airway (LMA) and the I-gel, in different head and neck positions in elderly patients undergoing elective urological surgery under general anesthesia. A total of 120 patients aged over 75 years with ASA physical status I-III will be randomly assigned to one of four groups: standard position with I-gel, right lateral rotation with I-gel, standard position with classic LMA, and right lateral rotation with classic LMA. The study will compare insertion time, ease and success of placement, number of attempts, hemodynamic responses, oropharyngeal leak pressures, fiberoptic scores, and airway-related complications. The findings aim to provide clinical guidance on the optimal use of supraglottic airway devices in geriatric patients in various head positions.",[207,208,209,210],"Airway Management Assessment","Supraglottic Airways","Supraglottic Airways for General Anesthesia","Laryngeal Mask Airways",[212,213,214,215,216,217,218,219],"Supraglottic airway device","i-gel","Classic laryngeal mask airway","Elderly patients","Airway management","Head position","General anesthesia","Insertion success","2025-09-10",{"date":222,"type":39},"2025-09-17",{"date":224,"type":39},"2025-06-20",{"date":226,"type":22},"2025-09-15",{"name":45,"class":46},{"id":229,"slug":230,"hasResults":11,"nctId":231,"briefTitle":232,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":234,"targetDuration":236,"studyType":58,"phases":4,"briefSummary":237,"conditions":238,"keywords":240,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":245,"startDateStruct":247,"completionDateStruct":249,"leadSponsor":251,"locationsCount":47},"100606046","investigation-of-the-relationship-between-ultrasonographic-parameters-and-tactile-sensation-in-carpal-tunnel-syndrome-100606046","NCT07170449","Investigation of the Relationship Between Ultrasonographic Parameters and Tactile Sensation in Carpal Tunnel Syndrome","Inclusion Criteria:\n\n* Electrodiagnostic diagnosis of carpal tunnel syndrome with pain, numbness, burning, and tingling consistent with the median nerve dermatomal area lasting at least 6 weeks.\n* Literate\n* Agree to participate in the study\n\nExclusion Criteria:\n\n* Concomitant diabetes, systemic inflammatory disease, active infection, and history of malignancy\n* Being \\\u003C18 and \\>65 years old\n* Being illiterate\n* Refusing to participate in the study\n* Having a disease with neuropathic pain, such as polyneuropathy, radiculopathy, or MS\n* Other concomitant upper extremity entrapment neuropathies (e.g., cubital tunnel syndrome)\n* Having undergone surgery for carpal tunnel syndrome\n* Rheumatoid arthritis, advanced hand osteoarthritis",{"count":235,"type":22},84,"3 Months","The aim of this study was to investigate the relationship between different ultrasonographic indices used in patients with carpal tunnel syndrome and the level of tactile sensation.\n\nThe primary questions the study aimed to answer are:\n\n• To what extent are the ultrasonographic parameters used in the diagnosis of carpal tunnel syndrome related to the level of sensory complaints in the patient?",[239],"Carpal Tunnel Syndrome (CTS)",[241,242,243],"Carpal Tunnel Syndrome","Ultrasonography","Tactile Sensation","2025-09-05",{"date":246,"type":39},"2025-09-12",{"date":248,"type":39},"2025-08-01",{"date":250,"type":22},"2026-04-30",{"name":45,"class":46},{"id":253,"slug":254,"hasResults":11,"nctId":255,"briefTitle":256,"officialTitle":256,"acronym":4,"eligibilityCriteria":257,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":258,"targetDuration":4,"studyType":23,"phases":260,"briefSummary":261,"conditions":262,"keywords":266,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":269,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":273,"locationsCount":274},"100593028","investigation-of-the-effectiveness-of-kinesiological-taping-in-cubital-tunnel-syndrome-100593028","NCT07001111","Investigation of the Effectiveness of Kinesiological Taping in Cubital Tunnel Syndrome","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Patients with at least 3 points of pain according to the Numeric Rating Scale (NRS)\n* Patients diagnosed with Cubital Tunnel Syndrome via Electroneuromyography (ENMG)\n* Literate\n* Willing to consent to participate in the study\n\nExclusion Criteria:\n\n* Having any secondary entrapment neuropathy such as diabetes, inflammatory arthritis, or hypothyroidism\n* Pregnancy\n* Active cancer presence\n* Skin infection, burns, wounds, or scars on the forearm\n* History of elbow trauma\n* Cervical radiculopathy or brachial plexopathy\n* Polyneuropathy\n* Having previously undergone Cubital Tunnel decompression surgery\n* Having received a corticosteroid injection into the Cubital Tunnel within the last 3 months\n* Illiterate\n* Not consenting to participate in the study",{"count":259,"type":22},36,[25],"This study aims to investigate the effect of kinesiological taping, applied in addition to exercise, on clinical symptoms in patients diagnosed with Cubital Tunnel Syndrome. The patients will be randomized into three groups (exercise, exercise + kinesiological taping, exercise + sham taping) and will be evaluated at the 1st and 3rd months after a 3-week treatment period.",[263,264,265],"Cubital Tunnel Syndrome","Kinesio Taping","Ulnar Neuropathies",[263,267,268],"Kinesio taping","ulnar neuropathies",{"date":246,"type":39},{"date":271,"type":39},"2025-04-21",{"date":192,"type":22},{"name":45,"class":46},2,{"id":276,"slug":277,"hasResults":11,"nctId":278,"briefTitle":279,"officialTitle":279,"acronym":4,"eligibilityCriteria":280,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":281,"enrollmentInfo":282,"targetDuration":4,"studyType":23,"phases":284,"briefSummary":285,"conditions":286,"keywords":291,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":292,"startDateStruct":293,"completionDateStruct":295,"leadSponsor":297,"locationsCount":274},"100589843","the-effect-of-kinesiotaping-on-posture-and-balance-in-patients-with-postural-thoracic-hyperkyphosis-100589843","NCT06959680","The Effect of Kinesiotaping on Posture and Balance in Patients With Postural Thoracic Hyperkyphosis","Inclusion Criteria:\n\n* Being between the ages of 18-45\n* Among the patients who applied to the physical medicine and rehabilitation outpatient clinic with poor posture or nonspecific back pain, the kyphosis angle was measured as ≥ 40 on the thoracic lateral radiograph\n* Being literate\n* Agreeing to participate in the research\n\nExclusion Criteria:\n\n* Patients younger than 18 years and older than 45 years\n* Spinal deformity, Scheuermann disease, disc herniation\n* Previous spine surgery and trauma\n* Neuromuscular, peripheral neuropathic disease\n* Pregnant and postmenopausal women\n* Vertigo disease (central or peripheral cause)\n* Use of medication that may cause dizziness (in the last 3 months)\n* Defect of vision\n* Presence of physical deformity or additional disease that will prevent exercise\n* Active skin disease in the area where tape will be applied","45 Years",{"count":283,"type":22},48,[25],"The primary aim of our research is to evaluate the positive effects of exercise and kinesiotaping on the thoracic kyphosis angle in young adults between the ages of 18-45 with a thoracic kyphosis angle of 40 degrees and above. Secondary aims are to investigate the effects of kinesiotaping on dynamic and static balance, pain, and quality of life in patients with thoracic hyperkyphosis.",[287,288,264,289,290],"Kyphosis Thoracic","Kyphosis Postural Thoracic","Postural Kyphosis","Balance",[290,289,267],{"date":246,"type":39},{"date":294,"type":39},"2025-04-29",{"date":296,"type":22},"2026-01-29",{"name":45,"class":46},{"id":299,"slug":300,"hasResults":11,"nctId":301,"briefTitle":302,"officialTitle":303,"acronym":4,"eligibilityCriteria":304,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":305,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":307,"conditions":308,"keywords":311,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":312,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":316,"locationsCount":47},"100589014","relationship-between-central-sensitization-symptoms-and-cognitive-dysfunction-in-fibromyalgia-100589014","NCT06948903","Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Fibromyalgia","Investigation of the Relationship Between Central Sensitization Symptoms and Cognitive Dysfunction in Patients With Fibromyalgia","Inclusion Criteria:\n\n* Being diagnosed with fibromyalgia according to American College of Rheumatology 2016 criteria\n* Being between 18-65 years old\n* Being literate\n* Accepting to participate in the study\n\nExclusion Criteria:\n\n* Concomitant systemic inflammatory disease, central nervous system disease (cortical involvement), active infection and malignancy history\n* History of illness that may lead to cognitive impairment\n* Being \\\u003C18 and \\>65 years old\n* Being illiterate\n* Not accepting to participate in the study",{"count":306,"type":22},100,"The aim of the study is to investigate the relationship between central sensitization parameters and cognitive dysfunction in patients with fibromyalgia.The main questions it aims to answer are:\n\nDo central sensitization symptoms affect cognitive dysfunction in patients with fibromyalgia? To what extent do central sensitization symptoms affect objective and subjective cognitive complaints in fibromyalgia patients? How do cognitive complaints relate to other clinical parameters, including disease severity, in these patients?",[67,309,310],"Cognitive Dysfunction","Central Sensitisation",[67,309,310],{"date":246,"type":39},{"date":314,"type":39},"2023-01-10",{"date":190,"type":22},{"name":45,"class":46},{"id":318,"slug":319,"hasResults":11,"nctId":320,"briefTitle":321,"officialTitle":322,"acronym":4,"eligibilityCriteria":323,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":324,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":326,"conditions":327,"keywords":330,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":332,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":337,"locationsCount":47},"100581498","investigation-of-the-relationship-between-central-sensitization-and-balance-in-fibromyalgia-100581498","NCT06851091","Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia","Investigation of the Relationship Between Central Sensitization Parameters and Balance Changes in Patients With Fibromyalgia","Inclusion Criteria:\n\n* Diagnosis of FMS according to the ACR 2016 diagnostic criteria\n* Being between the ages of 18 and 65\n* Being literate\n* Providing informed consent by signing the voluntary consent form\n\nExclusion Criteria:\n\n* Being under 18 years old or over 65 years old\n* Presence of vestibular disorders\n* Having undergone spinal and\u002For extremity surgery (such as for back\u002Fhip\u002Fknee\u002Ffoot) within the last 6 months\n* History of lower extremity amputation\n* Presence of spinal deformities\n* Peripheral arterial disease\n* Vitamin B12 deficiency\n* Any neurological disorder (e.g., stroke, traumatic brain injury, multiple sclerosis, Parkinson's disease, central nervous system malignancies, etc.)\n* Severe cardiopulmonary insufficiency (stage 3-4)\n* Uncontrolled systemic diseases such as hypertension and diabetes\n* Presence of systemic inflammatory diseases, malignancies, or active infections\n* Pregnancy",{"count":325,"type":22},75,"The aim of the study is to investigate the relationship between central sensitization parameters and changes in static and dynamic balance in patients with fibromyalgia.\n\nThe main questions it aims to answer are:\n\n* Do central sensitization parameters differ in patients with fibromyalgia compared to healthy individuals?\n* How is balance performance in these individuals compared to healthy controls?\n* Do central sensitization parameters affect static and dynamic balance in patients with fibromyalgia?\n* Do central sensitization parameters lead to quantitative changes in balance in patients with fibromyalgia?",[328,310,329],"Fibromyalgia Syndrome","Postural Balance",[67,310,331,329],"Balance Changes",{"date":246,"type":39},{"date":334,"type":39},"2025-02-18",{"date":336,"type":22},"2025-12",{"name":45,"class":46},{"id":339,"slug":340,"hasResults":11,"nctId":341,"briefTitle":342,"officialTitle":343,"acronym":4,"eligibilityCriteria":344,"healthyVolunteers":85,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":345,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":347,"conditions":348,"keywords":351,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":357,"startDateStruct":358,"completionDateStruct":360,"leadSponsor":362,"locationsCount":274},"100575878","investigation-of-ultrasonographic-measurements-of-lower-extremity-nerves-in-type-2-diabetes-patients-with-peripheral-polyneuropathy-100575878","NCT06778005","Investigation of Ultrasonographic Measurements of Lower Extremity Nerves in Type 2 Diabetes Patients With Peripheral Polyneuropathy","Investigation of the Relationship of Ultrasonographic Measurements of Lower Extremity Nerves With Gait and Balance Performance in Type 2 Diabetes Patients With Peripheral Polyneuropathy","Inclusion Criteria (Group 1):\n\n* Being between the ages of 18-65\n* Being literate\n* Signed a voluntary consent form agreeing to participate in the study\n\nInclusion Criteria (Group 2):\n\n* Diagnosed with Type 2 Diabetes based on at least one of the following diagnostic criteria: fasting plasma glucose ≥ 126 mg\u002Fdl, 2-hour plasma glucose ≥ 200 mg\u002Fdl in an oral glucose tolerance test, HbA1c ≥ 6.5%, or diabetes symptoms (excessive thirst, eating, urination, and weight loss) + random plasma glucose ≥ 200 mg\u002Fdl. (14)\n* Diagnosed with diabetic peripheral polyneuropathy through EMG evaluation in addition to Type 2 Diabetes.\n* Being between the ages of 18-65\n* Being literate\n* Signed a voluntary consent form agreeing to participate in the study.\n\nExclusion Criteria:\n\n* Individuals under 18 years old and over 65 years old\n* Diagnosed with Type 1 diabetes\n* Use of medications that can cause polyneuropathy\n* Other causes of neuropathic pain (lumbar radiculopathy, spinal stenosis, -hereditary, inflammatory, entrapment neuropathies)\n* Undergoing lower extremity surgery (spine\u002Fhip\u002Fknee\u002Ffoot) in the last 6 months\n* Having peripheral artery disease\n* B12 vitamin deficiency\n* Active foot ulcer\n* History of lower extremity amputation\n* Severe cardiopulmonary insufficiency (stage 3-4)\n* History of myocardial infarction within the last 1 month\n* History of unstable angina\n* Active systemic inflammatory diseases and active malignancy\n* Presence of vestibular disorders\n* Presence of cognitive impairment\n* Osteoarthritis in the lower extremity\n* Pregnancy\n* Body Mass Index (BMI) of 30 or higher",{"count":346,"type":22},86,"The aim of this study is to quantitatively evaluate ultrasonographic measurements of the lower extremity nerves in patients diagnosed with diabetic polyneuropathy and to investigate the relationship with gait, static and dynamic balance performance.\n\nIn this study, we aimed to investigate the effect of ultrasonographic findings of lower extremity nerves on quality of daily life, physical activity, gait and balance in patients with diabetic peripheral polyneuropathy.",[349,350],"Diabetes","Diabetic Polyneuropathy",[352,353,354,355,356],"polyneuropathy","Ultrasound","diabetes","balance","gait",{"date":246,"type":39},{"date":359,"type":39},"2025-01-01",{"date":361,"type":22},"2025-11-01",{"name":45,"class":46},{"id":364,"slug":365,"hasResults":11,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":85,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":370,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":372,"conditions":373,"keywords":374,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":244,"lastUpdatePostDateStruct":375,"startDateStruct":377,"completionDateStruct":379,"leadSponsor":381,"locationsCount":47},"100575311","investigation-of-central-sensitization-and-associated-factors-in-patients-with-lipedema-100575311","NCT06770634","Investigation of Central Sensitization and Associated Factors in Patients With Lipedema","Investigation of the Prevalence of Central Sensitization and Associated Factors in Patients With Lipedema","Inclusion Criteria:\n\n1. Lipedema; Diagnosis of lipedema Aged between 18 and 65 years Literate Willing to participate in the study\n2. control group; Being completely healthy (no internal\u002Fmetabolic issues such as diabetes, obesity, or hypothyroidism, and no diagnosis of lipedema) BMI ≤ 30 Aged between 18 and 65 years Literate Willing to participate in the study\n\nExclusion Criteria:\n\n1. Lipedema group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, or fibromyalgia Illiterate Not willing to participate in the study\n2. Control group; Under 18 or over 65 years of age Presence of concurrent lymphedema, chronic venous insufficiency, deep vein thrombosis, polyneuropathy, fibromyalgia, systemic rheumatic diseases, active cancer, infections, or pregnancy Illiterate Not willing to participate in the study",{"count":371,"type":22},50,"This study aims to investigate the presence of central sensitization and its associated parameters in patients with lipedema. Lipedema is a chronic and hereditary condition that primarily affects the lower extremities in women and is often associated with hormonal changes. Symptoms such as pain, swelling, and tenderness are common in lipedema, and these symptoms may be related to central sensitization. Additionally, the ultrasonographic findings and pain sensitivity in lipedema will be compared with those of healthy individuals. This study seeks to contribute to the diagnosis and treatment process of lipedema.",[140,310],[93,140],{"date":376,"type":39},"2025-09-08",{"date":378,"type":39},"2024-12-06",{"date":380,"type":22},"2025-12-30",{"name":45,"class":46},{"id":383,"slug":384,"hasResults":11,"nctId":385,"briefTitle":386,"officialTitle":387,"acronym":4,"eligibilityCriteria":388,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":281,"enrollmentInfo":389,"targetDuration":4,"studyType":23,"phases":391,"briefSummary":393,"conditions":394,"keywords":4,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":396,"lastUpdatePostDateStruct":397,"startDateStruct":399,"completionDateStruct":400,"leadSponsor":402,"locationsCount":47},"100602858","phase-4-efficacy-and-safety-evaluation-of-ruscus-aculeatus-l-in-patients-with-hemorrhoids-100602858","NCT07128979","Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With Hemorrhoids","Efficacy and Safety Evaluation of Ruscus Aculeatus L in Patients With Hemorrhoids: A Randomized, Double-blind Phase IV Clinical Trial","Inclusion Criteria:\n\n1. Patients between the ages of 18-45 with complaints (symptomatic) consistent with hemorrhoidal disease\n2. Patients with Stage II and III hemorrhoids according to the Goligher Hemorrhoid Rating system using physical examination (digital rectal examination, anoscopy\u002Frectoscopy performed within a maximum of four weeks before the examination)\n3. Patients who have signed the Informed Consent Form\n\nExclusion Criteria:\n\n* Patients aged \\\u003C18 and \\>45 years\n* Stage I and IV hemorrhoids according to the Goligher Hemorrhoid Rating system\n* Surgery for hemorrhoids at any time\n* Injection treatment for multiple hemorrhoids in the last 3 years\n* Perianal sepsis, inflammatory bowel disease, colorectal malignancy, or pre-existing sphincter injury within the last 3 years\n* Immunodeficiency\n* In addition to hemorrhoids, patients with anal fissures and perianal fistulas detected by simultaneous physical examination or anoscopy\u002Frectoscopy",{"count":390,"type":22},250,[392],"PHASE4","Hemorrhoidal disease is characterized by distal displacement and deterioration of structural integrity of vascular cushions in the anal canal, which physiologically help defecation and continence. Unlike advanced stage (stage IV) hemorrhoids, which require surgical intervention, various topical agents (gels, ointments, creams), oral venoactive drugs, homeopathic and phytotherapeutic products and nutritional supplements are widely used in stage II and III hemorrhoidal disease. The genus Ruscus (family Asparagaceae) is a group of plants native to the Mediterranean basin, Southern and Western Europe, and Iran, represented by perennial, rhizome-based, and evergreen shrubs. Among the species belonging to this genus, Ruscus aculeatus L. has the widest distribution area. The subsoil parts of the Ruscus plant are rich in steroidal saponins and show vasoconstrictor, diuretic, anti-inflammatory and venotonic effects, especially with ruscogenin and neoruscogenin compounds. Due to these properties, R. aculeatus stands out as a traditional phytotherapy agent that has been used for a long time in chronic venous insufficiency. However, there are no controlled clinical studies in the literature evaluating the efficacy and safety of Ruscus aculeatus L. in hemorrhoidal disease. Therefore, this study was aimed to systematically evaluate the contribution of a phytotherapeutic product containing R. aculeatus to the treatment of stage II-III hemorrhoidal patients and to provide scientific evidence of a new and potentially safe herbal treatment option that can be used in the treatment of hemorrhoids.",[395],"Hemorrhoid","2025-08-18",{"date":398,"type":39},"2025-08-19",{"date":248,"type":39},{"date":401,"type":22},"2026-11-02",{"name":45,"class":46},{"id":404,"slug":405,"hasResults":11,"nctId":406,"briefTitle":407,"officialTitle":408,"acronym":4,"eligibilityCriteria":409,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":55,"enrollmentInfo":410,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":412,"conditions":413,"keywords":415,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":419,"lastUpdatePostDateStruct":420,"startDateStruct":422,"completionDateStruct":424,"leadSponsor":426,"locationsCount":47},"100601778","symptom-distribution-and-pain-sensitization-in-carpal-tunnel-syndrome-100601778","NCT07114913","Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome","Evaluation of Central Sensitization Parameters Based on Extra Median Symptom Distribution in Carpal Tunnel Syndrome: A Cross-sectional Study","Inclusion Criteria:\n\n* Having been diagnosed with carpal tunnel syndrome based on clinical and electrodiagnostic findings\n* Being between 18 and 65 years of age\n* Being literate\n* Agreeing to participate in the study\n\nExclusion Criteria:\n\n* Having a history of concomitant diabetes, systemic inflammatory disease, active infection, or malignancy\n* Being \\\u003C18 and \\>65 years of age\n* Being illiterate\n* Refusing to participate in the study\n* Having a disease associated with neuropathic pain, such as polyneuropathy, radiculopathy, or multiple sclerosis\n* History of injection or surgery for CTS within the last 6 months",{"count":411,"type":22},80,"This study aims to compare central sensitization parameters between carpal tunnel syndrome (CTS) patients with extra median symptom distribution and those with typical, median nerve-related symptoms. Extra median sensory spread, observed in some CTS patients beyond the anatomical boundaries of the median nerve, may reflect central sensitization mechanisms. Using the Central Sensitization Inventory and pressure pain threshold measurements, this study will assess whether extra median symptom patterns are associated with increased central sensitization.",[241,310,414],"Pain, Radiating",[416,93,417,418],"carpal tunnel syndrome","central sensitization inventory","pressure pain threshold","2025-08-06",{"date":421,"type":39},"2025-08-11",{"date":423,"type":39},"2025-06-21",{"date":425,"type":22},"2026-03-01",{"name":45,"class":46},{"id":428,"slug":429,"hasResults":11,"nctId":430,"briefTitle":431,"officialTitle":432,"acronym":4,"eligibilityCriteria":433,"healthyVolunteers":85,"sex":54,"minAge":18,"maxAge":434,"enrollmentInfo":435,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":437,"conditions":438,"keywords":441,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":447,"lastUpdatePostDateStruct":448,"startDateStruct":450,"completionDateStruct":452,"leadSponsor":454,"locationsCount":47},"100470252","biomechanical-and-viscoelastic-properties-of-thoracolumbar-fascia-in-pregnancy-pelvic-girdle-pain-100470252","NCT05403424","Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnancy Pelvic Girdle Pain","Investigation of Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnant Women With Pelvic Girdle Pain","Inclusion Criteria:\n\n* First-time pregnancy\n* Pregnant women diagnosed with pelvic girdle pain in 1st and 2nd trimesters\n* Pregnant women who do not have pelvic girdle pain in 1st and 2nd trimesters\n* Women not being pregnant\n* Pre-pregnancy Body-Mass-Index (BMI) \\\u003C 30 kg\u002Fm2\n\nExclusion Criteria:\n\n* Presence of connective tissue disease\n* Deterioration of skin integrity in measurement areas\n* Presence of orthopedic, neurological, rheumatic problems that may cause musculoskeletal disorders and deviations from normal biomechanical alignment\n* History of spine, pelvis, or lower extremity surgery or fracture in the past 6 months\n* Definition of chronic low back-pelvic region pain (lasting for more than 3 months and pain severity \\>4 according to VAS) before pregnancy\n* Identification of metabolic disorders such as Type I, II diabetes, gestational diabetes mellitus (GDM), preeclampsia before and\u002For during pregnancy)","40 Years",{"count":436,"type":22},60,"It has not been objectively clarified how the thoracolumbar fascia (TLF) changes the biomechanical adaptations that occur in the lumbopelvic region during pregnancy and whether it is associated with pelvic girdle pain (PGP). Therefore, the aim of this study is to determine the biomechanical and viscoelastic properties of TLF, which adapts to the changes in the lumbopelvic region in pregnant women with pelvic girdle pain, and to investigate its relationship with PGP.",[439,440],"Pregnant Women","Pelvic Girdle Pain",[442,443,444,445,446],"pregnant women","pelvic girdle pain","thoracolumbar fascia","stiffness","creep","2024-09-04",{"date":449,"type":39},"2024-09-19",{"date":451,"type":39},"2022-06-01",{"date":453,"type":22},"2025-10-15",{"name":45,"class":46},{"id":456,"slug":457,"hasResults":11,"nctId":458,"briefTitle":459,"officialTitle":460,"acronym":4,"eligibilityCriteria":461,"healthyVolunteers":11,"sex":17,"minAge":462,"maxAge":463,"enrollmentInfo":464,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":466,"conditions":467,"keywords":469,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":474,"lastUpdatePostDateStruct":475,"startDateStruct":477,"completionDateStruct":479,"leadSponsor":481,"locationsCount":47},"100559327","assessment-of-methods-used-in-evaluating-balance-rehabilitation-in-parkinsons-patients-100559327","NCT06562686","Assessment of Methods Used in Evaluating Balance Rehabilitation in Parkinson's Patients","Assessment of Methods Used in Evaluating Balance Rehabilitation in Parkinson's Patients: Determination of Responsiveness and Minimal Clinically Important Difference Values","Inclusion Criteria:\n\n* Diagnosis of Parkinson's disease\n* Aged between 50-80 years\n* Modified Hoehn and Yahr stage 1.5 - 3\n* On stable medical treatment for the last 3 months\n* Mini-Mental State Examination score \\> 23\n* Approval of the informed consent form\n\nExclusion Criteria:\n\n* Age below 50 or above 80 years\n* Musculoskeletal disorders, severe osteoarthritis, peripheral neuropathy, or history of -previous lower extremity joint replacement\n* Cardiovascular disease, especially uncontrolled hypertension exceeding 180\u002F110 mm Hg at rest within the last four weeks, or recent myocardial infarction\n* Orthostatic hypotension\n* Body weight exceeding 100 kg\n* Respiratory system disease\n* Presence of severe dyskinesia, visual impairment, and uncontrolled on-off fluctuations","50 Years","80 Years",{"count":465,"type":22},83,"Balance rehabilitation holds an important place in the treatment of Parkinson's patients. Before and after treatment, patients are evaluated using various measurement methods. In calculations of changes post-treatment, although statistically significant changes are detected, clinical differences are often not observed. Jaeschke et al. developed the concept of minimal clinically important difference (MCID) to address this. They have worked on methods to determine the level of MCID. These measurements help clinicians understand which results can be interpreted as clinically meaningful for the patient.\n\nResponsiveness refers to how sensitive a measurement tool is to changes, whereas MCID focuses on determining whether these changes are clinically significant. Both concepts are crucial for understanding and interpreting the performance of measurement tools.\n\nIdentifying which patients have a high risk of balance problems and falls, and screening those at risk, is important for making treatment decisions. Determining which change values are clinically significant (MCID) and identifying which tests are more sensitive in detecting changes (responsiveness) are essential in monitoring patients.",[468],"Parkinson Disease",[355,470,471,472,473],"Biodex balance system","Responsiveness","MCID","Parkinson's disease","2024-08-17",{"date":476,"type":39},"2024-08-20",{"date":478,"type":22},"2024-08",{"date":480,"type":22},"2025-07",{"name":45,"class":46},{"id":483,"slug":484,"hasResults":11,"nctId":485,"briefTitle":486,"officialTitle":486,"acronym":4,"eligibilityCriteria":487,"healthyVolunteers":85,"sex":17,"minAge":462,"maxAge":4,"enrollmentInfo":488,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":490,"conditions":491,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":493,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":498,"leadSponsor":500,"locationsCount":47},"100551188","determination-of-risk-factors-of-shoulder-pathologies-in-parkinson-disease-100551188","NCT06456840","Determination of Risk Factors of Shoulder Pathologies in Parkinson Disease","Inclusion Criteria:\n\nGroup1\n\n* Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria\n* Being over 50 years old\n* Being in the Hoehn \\& Yahr stage I-IV range\n* Identification of pain in at least one shoulder (VAS\\>3)\n* Agreeing to participate in the study\n* Being literate\n\nGroup2\n\n* Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria\n* Being over 50 years old\n* Being in the Hoehn \\& Yahr stage I-IV range\n* No pain in both shoulders (VAS: 0)\n* Agreeing to participate in the study\n* Being literate\n\nGroup 3\n\n* Describe pain \\>3 on the visual pain scale in any shoulder\n* Being over 50 years old\n* Becoming literate\n* Agreeing to participate in the study\n\nGroup 4\n\n1. Not defining pain with a score of 0 on the visual pain scale in both shoulders\n2. Being over 50 years old\n3. Being literate\n4. Agreeing to participate in the study\n\nExclusion Criteria:\n\n* Scoring less than 24 points in the Mini Mental Test\n* Having had a myocardial infarction\n* Having had a cerebrovascular accident\n* Having a rheumatological disease\n* Known endocrine disease (Diabetes Mellitus, Hypo\u002Fhyperthyroidism)\n* Cervical disc herniation defining radiculopathy\n* Active trigger point palpated in the shoulder girdle muscles\n* Having had any shoulder surgery\n* Concomitant history of active systemic inflammatory disease, active infection and active malignancy\n* Physical Therapy modalities have been applied in the last 6 months\n* Having had an interventional procedure performed on the shoulder area within the last 6 months\n* Using medications that may cause tendinopathy (Fluoroquinolines)",{"count":489,"type":22},160,"Parkinson's disease was first described in history in 1817 by James Parkinson in his monograph \"An essay on swinging palsy\", and today it is the 2nd most common neurodegenerative disease after Alzheimer's, affecting approximately 6.1 million people. Its main histopathological feature is the decrease in dopaminergic secretion in the basal ganglia and there are three cardinal findings: Bradykinesia, Tremor, Rigidity. Although joint and skeletal deformities are seen in approximately 70% of Parkinson's patients, they are not adequately evaluated and cause significant functional disability and chronic pain, independent of motor symptoms.Musculoskeletal pathologies seen in Parkinson's patients can be classified as: musculoskeletal pain, articular problems, postural problems and bone mineralization defects. The shoulder girdle is a joint with complex and delicate function, consisting of four joints (glenohumeral, sternoclavicular, acromioclavicular and scapulothoracic), supporting muscles and periarticular ligaments, which seriously affects the patient's quality of daily life and function. Although magnetic resonance imaging (MRI) is the best imaging tool in the diagnosis of musculoskeletal system pathologies, it is quite sensitive to artifact-forming motion. Ultrasound (US) imaging is widely used in the evaluation of rotator cuff muscles, biceps muscle and glenohumeral joint pathologies and has many advantages over MRI, such as providing fast, cheap and dynamic imaging. Although many studies have proven that shoulder girdle musculoskeletal pathologies such as bicipital tendinitis, m.supraspinatus tendinosis, subacromial\u002Fsubdeltoid bursitis, subacromial impingement syndrome, and adhesive capsulitis are seen more frequently in Parkinson's patients by ultrasonographic imaging, these shoulder girdle pathologies seen in Parkinson's patients are more common. The risk factors for pathologies have not been defined. In this study, we aimed to determine the ultrasonographic findings and risk factors of shoulder pathologies in Parkinson's patients and to investigate the effects of shoulder pathologies on quality of daily life, physical activity, falls and balance.",[468,492],"Shoulder Pain","2024-06-07",{"date":495,"type":39},"2024-06-13",{"date":497,"type":22},"2024-07-15",{"date":499,"type":22},"2024-12-30",{"name":45,"class":46},""]