[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Taipei City Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":146},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,53,83,107,128],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100634332","laser-acupuncture-for-fatigue-in-hemodialysis-patients-100634332",false,"NCT07538310","Laser Acupuncture for Fatigue in Hemodialysis Patients","Laser Acupuncture Improves Fatigue and Quality of Life in Hemodialysis Patients: a Randomized Double-blind Clinical Trial Pilot Study","LA-HD-Fatigue","Inclusion Criteria:\n\n* Patients with End-Stage Renal Disease (ESRD) who require regular maintenance hemodialysis.\n* Must undergo hemodialysis treatment at least 3 times per week.\n* Aged 18 years or older.\n* Willing and able to provide informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Presence of acute infectious symptoms.\n* Unstable vital signs.\n* Diagnosis of malignant tumors.\n* Pregnancy.\n* Presence of open wounds at the sites designated for laser intervention.\n* Patients with implanted cardiac pacemakers or other cardiac devices.","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis. It will also learn about how laser acupuncture affects blood circulation and autonomic nervous system balance.\n\nThe main questions it aims to answer are:\n\n1. Does laser acupuncture reduce the severity of fatigue and its interference with daily life?\n2. Can laser acupuncture improve related symptoms such as insomnia, poor appetite, and skin itching?\n3. How does laser acupuncture affect objective markers like microcirculation and heart rate variability? Researchers will compare laser acupuncture to a sham treatment (a look-alike procedure using a device that does not emit a laser) to see if laser acupuncture works to treat fatigue.\n\nParticipants will:\n\n1. Receive laser acupuncture or a sham treatment during their regular hemodialysis sessions 3 times a week for 4 weeks.\n2. Have their fatigue and life quality assessed through questionnaires on the first day, at 4 weeks, and at 8 weeks.\n3. Undergo non-invasive tests to measure microcirculation, heart rate variability, and pulse waves, and have photos of their tongue taken for Chinese medicine assessment.",[27,28,29],"ESRD (End Stage Renal Disease)","Dialysis","Fatigue",[31,32,33,34,29,35,36,37,38,39],"Hemodialysis","End-Stage Renal Disease","Laser Acupuncture","Photobiomodulation","Quality of Life","Microcirculation","Low-Level Laser Therapy","Traditional Chinese Medicine","Heart Rate Variability","NOT_YET_RECRUITING","2026-04-12",{"date":43,"type":44},"2026-04-20","ACTUAL",{"date":46,"type":21},"2026-04-08",{"date":48,"type":21},"2027-08-31",{"name":50,"class":51},"Taipei City Hospital","OTHER_GOV",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":52},"100542003","tcm-therapy-program-impact-on-breast-cancer-patients-vital-energy-100542003","NCT06337214","TCM Therapy Program Impact on Breast Cancer Patients' Vital Energy","A Holistic Medical Approach - The Effect of \"Traditional Chinese Medicine Therapy Program for Reinforcing Vital Energy\" on Breast Cancer Patients Undergoing Cancer Therapy","Inclusion Criteria:\n\n* Individuals aged 18 years and above and below 85 years, willing to voluntarily participate in the study.\n* Diagnosed with malignant breast tumors, ICD-10: C50, by conventional medicine.\n* Patients currently undergoing cancer treatment, including chemotherapy, radiotherapy, or targeted therapy.\n\nExclusion Criteria:\n\n* Diagnosed solely with carcinoma in situ or benign tumors, including fibrocystic breast conditions, by conventional medicine.\n* Patients regularly receiving Astragalus polysaccharide injections.\n* Patients with a history of allergies to Traditional Chinese Medicine.\n* Pregnant or breastfeeding women.\n* Individuals with a drug addiction habit, including both narcotic and non-narcotic drugs.\n* Any other situation where the participant is unable to cooperate (e.g., due to any factor that prevents participation, deemed unsuitable for participation by study staff, unwillingness to sign the consent form).","85 Years",{"count":62,"type":21},80,[24],"The goal of this study is to evaluate the impact of the \"Traditional Chinese Medicine Therapy Program for Reinforcing Vital Energy\" on patients with breast cancer who are currently undergoing conventional Western medical treatments in Taiwan. The main questions it aims to answer are:\n\nCan the \"Traditional Chinese Medicine Therapy Program\" alleviate symptoms experienced by breast cancer patients? Does the program improve the quality of life for breast cancer patients receiving Western medical treatments? How does the program contribute to the management of side effects associated with Western oncological therapies?\n\nParticipants will:\n\nEngage in the \"Traditional Chinese Medicine Therapy Program for Reinforcing Vital Energy\" provided by the Taiwan Compassionate Cancer Care Association.\n\nReceive supportive and educational services, including auxiliary Chinese medicine treatment courses, lifestyle and health education, and psychological counseling.\n\nThis study seeks to integrate the concept of holistic healthcare, emphasizing coordinated care that encompasses physical, mental, and social aspects, into the treatment of breast cancer.",[66,67,68,69],"Breast Cancer","Neoplasm, Breast","Patient Participation","Mental Health Issue",[66,71,72,73],"Reinforcing Vital Energy","Patients Association","Patients Educatioin","RECRUITING","2025-05-31",{"date":77,"type":44},"2025-06-04",{"date":79,"type":44},"2024-03-13",{"date":81,"type":21},"2025-12-31",{"name":50,"class":51},{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":88,"acronym":4,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":97,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":52},"100506312","theta-burst-stimulation-for-gambling-disorder-100506312","NCT05872750","Theta Burst Stimulation for Gambling Disorder","Rolling Deep With Gambling Disorder: From Building up of Scales, Biomarkers to Therapeutic Innovation","Inclusion Criteria:\n\n1. age between 18 and 65 years;\n2. fulfilling at least 4 of the Diagnostic and Statistical Manual version 5 (DSM-5) criteria of gambling disorder for at least 12-month assessed by the Structured Clinical Interview\n\nExclusion Criteria:\n\n1. Inability to provide informed consent or comprehend the study procedure;\n2. A major psychiatric illness that required chronic psychotropic medication or inpatient treatment, including schizophrenia spectrum disorder, bipolar spectrum disorder, and major depressive disorder with psychotic features.\n3. A current DSM-5 diagnosis of substance use disorder except nicotine use disorder or the use of one to two low-potency benzodiazepine tablets for sleep impairment;\n4. Have known preexisting noise-induced hearing loss, concurrent treatment with ototoxic medications, or with cochlear implants.\n5. Unstable medical illness, including malignancy, uncontrolled diabetes mellitus, unstable cardiac disease or recent myocardial infarction, or cerebrovascular or cardiovascular risk factors that require intensive medical management\n6. On medications known to lower seizure threshold (e.g., TCA, bupropion, clozapine)\n7. Implants controlled by physiological signals, including pacemaker, implantable cardioverter defibrillator, cochlear implant.\n8. Metallic objects in the head, including stenting, suture.\n9. Elevated risk of seizure due to traumatic brain history, seizure history, and head trauma, intracranial lesion, and alcohol or benzodiazepines withdrawal syndrome, stimulant intoxication.","65 Years",{"count":92,"type":21},75,[24],"The goal of this clinical trial is to investigate the efficacy of theta burst stimulation in individuals with gambling disorder. The main goal is to compare the severity of gambling problems following 2 weeks of intervention between active group and sham group. Participants will be randomized into active and sham group. The severity of gambling problems are assessed by self-reported questionaires.",[96],"Gambling Disorder",[98,96],"theta burst stimulation","2023-05-14",{"date":101,"type":44},"2023-05-24",{"date":103,"type":44},"2023-04-17",{"date":105,"type":21},"2026-06",{"name":50,"class":51},{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":11,"sex":17,"minAge":114,"maxAge":90,"enrollmentInfo":115,"targetDuration":4,"studyType":22,"phases":117,"briefSummary":118,"conditions":119,"keywords":120,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":123,"startDateStruct":125,"completionDateStruct":126,"leadSponsor":127,"locationsCount":52},"100504928","the-effect-of-theta-burst-stimulation-on-serum-bdnf-100504928","NCT05854706","The Effect of Theta-burst Stimulation on Serum BDNF","Antidepressant Effect of Prolonged Intermittent Theta-burst Stimulation on Serum Brain-derived Neurotrophic Factor Levels of Patients With Depression: A Randomized, Double-Blind, Sham-Controlled Study","Inclusion Criteria:\n\n1. age between 20 and 65 years;\n2. fulfilling the Diagnostic and Statistical Manual version 5 (DSM-5) criteria of Major depressive disorder assessed by the Structured Clinical Interview\n\nExclusion Criteria:\n\n1. Inability to provide informed consent or comprehend the study procedure;\n2. A major psychiatric illness including schizophrenia spectrum disorder, bipolar spectrum disorder, and major depressive disorder with psychotic features.\n3. A current DSM-5 diagnosis of substance use disorder except nicotine use disorder or the use of one to two low-potency benzodiazepine tablets for sleep impairment;\n4. Have known preexisting noise-induced hearing loss, concurrent treatment with ototoxic medications, or with cochlear implants.\n5. Unstable medical illness, including malignancy, uncontrolled diabetes mellitus, unstable cardiac disease or recent myocardial infarction, or cerebrovascular or cardiovascular risk factors that require intensive medical management\n6. On medications known to lower seizure threshold (e.g., TCA, bupropion, clozapine)\n7. Implants controlled by physiological signals, including pacemaker, implantable cardioverter defibrillator, cochlear implant.\n8. Metallic objects in the head, including stenting, suture.\n9. Elevated risk of seizure due to traumatic brain history, seizure history, and head trauma, intracranial lesion, and alcohol or benzodiazepines withdrawal syndrome, stimulant intoxication.","20 Years",{"count":116,"type":21},60,[24],"The goal of this clinical trial is to investigate the effect of theta burst stimulation for depression and serum brain-derived neurotrophic factor (BDNF) in individuals with major depression. The main question it aims to answer is whether 10 sessions of theta burst stimulation can influence the serum level of BDNF.\n\nParticipants will be randomized into active group and sham group. Researchers will compare the level of BDNF in these groups.",[96],[121],"Brain-Derived Neurotrophic Factor, Theta Burst Stimulation","2023-05-02",{"date":124,"type":44},"2023-05-11",{"date":103,"type":44},{"date":105,"type":21},{"name":50,"class":51},{"id":129,"slug":130,"hasResults":11,"nctId":131,"briefTitle":132,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":114,"maxAge":90,"enrollmentInfo":135,"targetDuration":4,"studyType":22,"phases":136,"briefSummary":137,"conditions":138,"keywords":140,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":122,"lastUpdatePostDateStruct":142,"startDateStruct":143,"completionDateStruct":144,"leadSponsor":145,"locationsCount":52},"100504927","trans-cranial-direct-current-stimulation-on-alcohol-craving-100504927","NCT05854693","Trans-cranial Direct Current Stimulation on Alcohol Craving","Exploring the Effect of Trans-cranial Direct Current Stimulation on Craving and Serum BDNF of Patients With Alcohol Dependence","Inclusion Criteria:\n\n1. Be between 20-65 years of age\n2. have sufficient cognitive function to understand the study and complete the informed consent process\n3. Be diagnosed with alcohol dependence as defined by DSM-IV through a structured interview (Mini-International Neuropsychiatric Interview, M.I.N.I.)\n\nExclusion Criteria:\n\n1. Intellectual disabilities\n2. bipolar disorder\n3. Psychosis (schizophrenia)\n4. Major physical illness (brain hemorrhage, brain tumor, myocardial infarction, epilepsy or history of seizures)\n5. intracorporeal electronic or metal implants (e.g., cardiac pacemaker)\n6. Pregnant or breastfeeding women\n7. Allergy to headgear and electrode materials\n8. Trauma or infection to the head\n9. Intracranial space occupied lesion (such as brain tumor, AVM, etc.) or patients who have undergone brain surgery, meningitis and encephalitis\n10. Patients who are expected to undergo brain and major surgery during the trial period",{"count":116,"type":21},[24],"The goal of thisclinical trial is to investigate the efficacy of trans cranial direct current stimulation (tDCS) for alcohol craving in individuals with alcohol dependence. The main question it aims to answer is whether 10 sessions of tDCS can reduce craving for alcohol.\n\nParticipants will be randomized into active group and sham group. Researchers will compare the severity of craving in these groups.",[139],"Alcohol Dependence",[141],"Transcranial Direct Current Stimulation, craving",{"date":124,"type":44},{"date":103,"type":44},{"date":105,"type":21},{"name":50,"class":51},""]