[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Taipei Medical University Shuang Ho Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":408},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,51,76,99,122,159,186,209,236,268,291,319,345,361,387],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100626444","facilitating-surgical-choice-in-patient-with-chronic-hypertrophic-rhinitis-using-a-patient-decision-aid-100626444",false,"NCT07435714","Facilitating Surgical Choice in Patient With Chronic Hypertrophic Rhinitis Using a Patient Decision Aid","Facilitating Surgical Choice in Patient With Chronic Hypertrophic Rhinitis Using a Patient Decision Aid: A Randomized Control Trial","Inclusion Criteria:\n\n* Diagnosed with chronic hypertrophic rhinitis.\n* Outpatients or inpatients scheduled to undergo surgical intervention.\n* Aged 18 years or older and able to communicate in Chinese.\n\nExclusion Criteria:\n\n* Presence of other structural nasal pathologies (e.g., nasal polyps, tumors).\n* Patients undergoing emergency surgery.\n* Individuals unable to live independently or fully comprehend the questionnaire content.\n* Individuals unable to complete the questionnaires.","ALL","18 Years",{"count":19,"type":20},158,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study is a prospective randomized controlled trial that aims to enroll 158 patients diagnosed with chronic hypertrophic rhinitis who are candidates for inferior turbinate surgery. Participants will be randomly assigned to either the \"standard group\" or the \"PDA group.\" The standard group will receive conventional shared decision-making (SDM) explanations using verbal and visual aids, while the PDA group will additionally receive a printed patient decision aid (PDA) to assist in evaluating the pros and cons of each surgical option. The study will assess patients' decision certainty and decision regret using the SURE scale and the Decision Regret Scale (DRS), respectively, administered before surgery and one month postoperatively. Surgical satisfaction and outcomes will also be evaluated using pre- and postoperative symptom questionnaires. All data will be collected and analyzed by blinded outcome assessors to ensure objectivity. This study involves no invasive procedures and is classified as a low-risk behavioral study. The primary aim is to optimize clinical decision-making processes for patients with chronic hypertrophic rhinitis considering surgical intervention in the otolaryngology setting.",[26],"Allergic Rhinitis",[28,29,30,31,32,33,34,35,36,37],"hypertrophic rhinitis","shared decision making","patient decision aid","Carbon dioxide laser turbinoplasty","Submucosal resection of the inferior turbinate","Microdebrider-assisted inferior turbinoplasty","Radiofrequency thermal ablation of the inferior turbinate","Potassium Titanyl Phosphate laser turbinoplasty","rhinitis","chronic hypertrophic rhinitis","RECRUITING","2026-05-11",{"date":41,"type":42},"2026-05-14","ACTUAL",{"date":44,"type":42},"2026-03-01",{"date":46,"type":20},"2027-07-31",{"name":48,"class":49},"Taipei Medical University Shuang Ho Hospital","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":60,"studyType":61,"phases":4,"briefSummary":62,"conditions":63,"keywords":4,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":50},"100636150","3d-printed-mobile-phone-holder-for-individuals-with-upper-limb-impairments-100636150","NCT07561944","3D-Printed Mobile Phone Holder for Individuals With Upper Limb Impairments","Design and Implementation of a 3D-Printed Mobile Phone Holder Selection and Fitting Process for Individuals With Upper Limb Functional Impairments","Inclusion Criteria:\n\n* Currently receiving occupational therapy in the Department of Physical Medicine and Rehabilitation.\n* Onset of condition \\> 3 months.\n* Presence of upper-limb functional impairment that causes difficulty or limitations in smartphone use.\n* Able to understand instructions for using the assistive device.\n* Montreal Cognitive Assessment (MoCA) score \\> 24.\n\nExclusion Criteria:\n\n* Age younger than 18 years.\n* Severe visual or hearing impairments that would affect the ability to perform smartphone tasks.\n* Unstable medical condition that may interfere with participation in the study.",{"count":59,"type":20},30,"1 Week","OBSERVATIONAL","Individuals with upper limb functional impairments, such as those resulting from stroke, spinal cord injury, musculoskeletal disorders, or degenerative joint disease, often experience difficulties operating smartphones. Standard devices typically require bilateral, precise fine motor control, which can limit independence, participation, and access to digital communication for this population. Although assistive products such as phone stands, straps, or styluses are available, they are often designed as \"one-size-fits-all,\" lack individualization, and may not be well integrated into daily life.\n\nThree-dimensional (3D) printing offers advantages of customization, modularity, low cost, and rapid production, and may support better matching between users and assistive devices. However, in clinical practice, the use of 3D-printed assistive technology is constrained by the lack of an integrated resource platform and standardized fitting procedures.\n\nThis exploratory intervention study aims to develop a 3D assistive device selection interface and a standardized fitting process for smartphone-related devices targeting adults with upper limb dysfunction. Approximately 30 outpatients will be recruited from a regional teaching hospital in northern Taiwan and will receive a 1-week intervention using a 3D-printed mobile phone holder or related assistive device, with occupational therapist support. Pre- and post-intervention assessments will examine smartphone task performance and satisfaction with the assistive technology. Feasibility, usability, and preliminary effectiveness will be evaluated to inform the development of a sustainable clinical service model.",[64,65,66,67],"Upper Limb Dysfunction","Hand Function Impairment","Musculoskeletal Disorders Affecting Hand Function","Difficulty Operating Smartphones Due to Upper Limb Impairment","NOT_YET_RECRUITING","2026-05-06",{"date":39,"type":42},{"date":72,"type":20},"2026-06-01",{"date":74,"type":20},"2026-12-30",{"name":48,"class":49},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":11,"sex":16,"minAge":83,"maxAge":4,"enrollmentInfo":84,"targetDuration":4,"studyType":21,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":50},"100601077","dance-intervention-to-improve-executive-function-and-physical-performance-in-older-adults-with-cognitive-impairment-100601077","NCT07105800","Dance Intervention to Improve Executive Function and Physical Performance in Older Adults With Cognitive Impairment","A Pilot Study of Dance Intervention for Enhancing Executive Function and Physical Performance in Cognitively Impaired Older Adults","Inclusion Criteria:\n\n* Subjective Cognitive Decline (SCD) with a score ≥5 on the SCD-Q9 questionnaire, or Mild Behavioral Impairment (MBI) with a score ≥7 on the MBI-Checklist, with symptoms persisting for more than three months.\n* Ability to follow instructions.\n* Ability to stand unsupported or with assistive devices for at least 10 minutes.\n* Ability to walk at least 10 meters, either unsupported or with assistive devices.\n\nExclusion Criteria:-Age below 55 years.\n\n* Severe visual or hearing impairment.\n* Score \\\u003C16 on the Montreal Cognitive Assessment (MoCA).\n* Emotional or anxiety symptoms caused by psychiatric medications that significantly impair the ability to perform study-related motor tasks.","55 Years",{"count":85,"type":20},50,[23],"This pilot study investigates the effects of a music-based dance intervention on executive function and physical performance in middle-aged and older adults with cognitive impairment. Dance, as a form of dual-task training, integrates music, rhythmic movement, and cognitive-motor coordination. When combined with group interaction and partner-guided physical cues, it has the potential to enhance both cognitive and motor functions simultaneously.\n\nThe intervention features a simple, structured dance sequence designed to stimulate rhythm, attention, and coordination through music-based movement. This study aims to evaluate the feasibility and preliminary efficacy of this approach in improving executive function and lower limb physical performance among individuals with cognitive impairment.",[89,90],"Older Adults","Cognitive Impairment, Mild","2026-04-27",{"date":93,"type":42},"2026-04-28",{"date":95,"type":42},"2025-11-01",{"date":97,"type":20},"2026-06-30",{"name":48,"class":49},{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":106,"enrollmentInfo":107,"targetDuration":4,"studyType":21,"phases":109,"briefSummary":110,"conditions":111,"keywords":113,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":50},"100554762","the-effect-of-doppler-ultrasound-on-calcified-tendinitis-100554762","NCT06503302","The Effect of Doppler Ultrasound on Calcified Tendinitis","The Effect of Doppler Ultrasound on Calcified Tendinitis: a Double Blind, Randomized Controlled Trial","Inclusion Criteria:\n\n1. chronic shoulder pain for more than 1 month\n2. shoulder X-ray showed calcified deposit\n\nExclusion Criteria:\n\n1. patient with needle phobia\n2. patient with known allergy to medication like Triamcinolone and Lidocaine","80 Years",{"count":108,"type":20},100,[23],"Calcific tendinitis of the shoulder, is a self-limiting disease characterized by the deposition of calcium phosphate crystals in the rotator cuff tendons. Patients will develop complications such as decreased range of motion of the shoulder joint, and thus reducing their quality of life. The most common site of occurrence is 1.5-2 cm away from the supraspinatus tendon insertion site on the greater tuberosity. The primary treatment for calcific tendinitis is conservative, such as non-steroidal anti-inflammatory analgesics for pain relieving, extracorporeal shock wave therapy, subacromial steroid injections, ultrasound-guided barbotage technique for aspirating and washing out calcific deposits. Ultrasound is being used in calcified tendinitis for evaluating its size, location, quality, and also using the color Doppler ultrasonography to evaluate its reactive inflammatory changes. However, the use of color Doppler ultrasonography in diagnosing and treating a shoulder pain with calcification is not being concluded yet. Therefore, the aim of this study is to evaluate the efficacy of color Doppler ultrasonography in calcified tendinitis.",[112],"Calcific Tendinitis of Shoulder",[114],"Doppler ultrasound",{"date":116,"type":42},"2026-05-01",{"date":118,"type":42},"2024-07-10",{"date":120,"type":20},"2026-06",{"name":48,"class":49},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":127,"acronym":128,"eligibilityCriteria":129,"healthyVolunteers":130,"sex":16,"minAge":131,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":21,"phases":135,"briefSummary":136,"conditions":137,"keywords":142,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":152,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":156,"leadSponsor":158,"locationsCount":4},"100622212","on-demand-ai-support-via-line-based-gpt-assistant-to-improve-emotional-resilience-and-reduce-burnout-among-clinical-nurses-100622212","NCT07380685","On-Demand AI Support Via LINE-Based GPT Assistant to Improve Emotional Resilience and Reduce Burnout Among Clinical Nurses","A Human-Centered, On-Demand AI Emotional Support Intervention Using a LINE-Based GPT Assistant to Enhance Resilience, Reduce Compassion Fatigue, and Improve Occupational Well-Being Among Clinical Nurses: A Prospective Interventional Study","Nurse-AI-CARE","Inclusion Criteria:\n\n1. Adults aged 20 to 65 years.\n2. Currently employed as clinical nursing staff in the participating institution, including inpatient wards or intensive care units.\n3. Able to read Traditional Chinese and receive daily messages via LINE or Email.\n4. Willing to participate and able to provide written informed consent.\n5. Expected to remain employed in the clinical unit for the full 4-week study period (not planning resignation or extended leave).\n\nExclusion Criteria:\n\n1. Refusal or inability to provide informed consent.\n2. Unable to receive daily messages through LINE or Email (e.g., no smartphone or internet access).\n3. Currently undergoing psychiatric treatment or in the acute phase of major physical\u002Fmental illness, where participation may interfere with clinical care.\n4. Cognitive or communication impairments that prevent understanding of study material or completion of questionnaires.",true,"20 Years","65 Years",{"count":134,"type":20},120,[23],"Clinical nurses are frequently exposed to high emotional demands due to heavy workloads, time pressure, patient suffering, and the interpersonal complexity of clinical care. These stressors may contribute to compassion fatigue, burnout, reduced resilience, and decreased occupational well-being. However, timely and accessible psychological support is often limited in busy clinical environments, and many nurses may hesitate to seek help due to stigma, time constraints, or limited resources.\n\nThis study is a prospective, randomized, controlled, parallel-group interventional trial designed to evaluate the feasibility and effectiveness of an on-demand, human-centered emotional support intervention delivered through a LINE-based GPT assistant. The AI assistant provides real-time supportive conversations, reflective prompts, stress-coping guidance, and resilience-enhancing strategies tailored specifically for clinical nurses, offering a private and easily accessible support resource.\n\nEligible clinical nurses (target sample size: 100-120) are randomly assigned to either an Intervention Group, which interacts with the AI assistant, or a Control Group, which receives non-interactive static messages, over a four-week intervention period. Primary outcomes include changes in compassion fatigue, burnout, and compassion satisfaction, as measured by the Professional Quality of Life Scale (ProQOL). Secondary outcomes include changes in resilience (Brief Resilience Scale), general self-efficacy (General Self-Efficacy Scale), and perceived stress (Perceived Stress Scale-10).\n\nThe results of this study are expected to provide evidence on the feasibility and potential effectiveness of AI-based emotional support as a scalable and accessible tool to promote psychological well-being among clinical nurses, thereby informing future digital mental health interventions in healthcare settings.",[138,139,140,141],"Occupational Stress and Mental Health in Clinical Nurses","Burnout","Compassion Fatigue","Psychological Resilience",[143,144,145,146,147,148,140,149,150,151],"AI-based supportive intervention","ChatGPT","LINE platform","Clinical Nursing","Emotional Resilience","Occupational Burnout","Digital Mental Health","Self-Efficacy","Perceived Stress","2026-03-09",{"date":154,"type":42},"2026-03-11",{"date":116,"type":20},{"date":157,"type":20},"2026-09-25",{"name":48,"class":49},{"id":160,"slug":161,"hasResults":11,"nctId":162,"briefTitle":163,"officialTitle":164,"acronym":165,"eligibilityCriteria":166,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":4,"enrollmentInfo":167,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":168,"conditions":169,"keywords":171,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":180,"startDateStruct":182,"completionDateStruct":184,"leadSponsor":185,"locationsCount":50},"100612731","fall-risk-assessment-in-parkinsons-disease-using-kinetikos-health-100612731","NCT07257393","Fall Risk Assessment in Parkinson's Disease Using Kinetikos Health","Validation of a Mobile Health Application for Fall Risk Assessment in Parkinson's Disease: A Comparative Study Before and After Dopaminergic Medication Adjustment","PD_FALLRISK","Inclusion Criteria:\n\n1. Age ≥20;\n2. PD diagnosis (MDS criteria);\n3. On levodopa monotherapy with motor fluctuations;\n4. Planned to start opicapone or safinamide;\n5. Consent provided.\n\nExclusion Criteria:\n\n1. Atypical\u002Fsecondary parkinsonism;\n2. Moderate-severe dementia;\n3. DBS\u002FMRgFUS\u002Fneurosurgery within 6 months;\n4. Severe comorbidities limiting test",{"count":108,"type":20},"This is a single-center, prospective observational study aiming to validate the Kinetikos Health App for fall risk assessment in PD patients undergoing dopaminergic medication adjustments.",[170],"Idiopathic Parkinsonism",[172,173,174,175,176,177,178],"Parkinson's disease","Fall risk","Motor fluctuation","Dopaminergic medication","Mobile health","Sit-to-Stand","Kinetikos Health App","2025-12-03",{"date":181,"type":42},"2025-12-04",{"date":183,"type":20},"2025-12-01",{"date":97,"type":20},{"name":48,"class":49},{"id":187,"slug":188,"hasResults":11,"nctId":189,"briefTitle":190,"officialTitle":190,"acronym":4,"eligibilityCriteria":191,"healthyVolunteers":11,"sex":16,"minAge":192,"maxAge":193,"enrollmentInfo":194,"targetDuration":4,"studyType":21,"phases":195,"briefSummary":196,"conditions":197,"keywords":200,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":179,"lastUpdatePostDateStruct":202,"startDateStruct":204,"completionDateStruct":206,"leadSponsor":208,"locationsCount":50},"100610652","clinical-validation-of-ai-powered-smart-vehicle-assisted-gait-training-in-neurodegenerative-disorders-100610652","NCT07230366","Clinical Validation of AI-powered Smart Vehicle Assisted Gait Training in Neurodegenerative Disorders","Inclusion Criteria:\n\n1. Patients with neurodegenerative diseases (such as Parkinson's disease or dementia).\n2. Age between 50-85 years.\n3. Capable of walking for at least 10 meters, but may have unsteady gait or history of falls.\n4. Able to understand the trial procedures and give informed consent.\n\nExclusion Criteria:\n\n1. Severe cardiopulmonary disease or recent major surgery.\n2. Unable to walk or requiring comprehensive physical support.\n3. Severe cognitive impairment preventing understanding of the trial procedures or giving informed consent.\n4. Visual or auditory impairments severe enough to prevent following trial instructions.","50 Years","85 Years",{"count":134,"type":20},[23],"This study aims to verify the safety and preliminary clinical benefits of long-term gait training using AI-powered smart electric vehicles for patients with neurodegenerative diseases such as Parkinson's disease and dementia.",[198,199],"Parkinson's Disease (PD)","Dementia",[201],"Neurodegenerative Diseases, Smart Electric Vehicles, Gait Training",{"date":203,"type":42},"2025-12-10",{"date":205,"type":20},"2026-01-02",{"date":207,"type":20},"2028-12-31",{"name":48,"class":49},{"id":210,"slug":211,"hasResults":11,"nctId":212,"briefTitle":213,"officialTitle":213,"acronym":214,"eligibilityCriteria":215,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":216,"enrollmentInfo":217,"targetDuration":4,"studyType":61,"phases":4,"briefSummary":219,"conditions":220,"keywords":222,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":228,"lastUpdatePostDateStruct":229,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":50},"100607706","investigation-of-using-non-wearable-devices-to-assess-sleep--disordered-breathing-in-hospitalized-patients-with-schizophrenia-100607706","NCT07192042","Investigation of Using Non-Wearable Devices to Assess Sleep- Disordered Breathing in Hospitalized Patients With Schizophrenia","IUNWD","Inclusion Criteria:\n\n* Age: Participants must be between 20 and 70 years old.\n* Diagnostic Criteria: Schizophrenia spectrum disorders, including schizophrenia, schizoaffective disorder, and schizophreniform disorder, diagnosed according to DSM-5 criteria and confirmed with the MINI 7.0 (Chinese version).\n* Clinical Stability and Informed Consent: At the time of admission, participants should be in a relatively stable condition, able to understand the study procedures, and capable of providing written informed consent. If patients are unable to fully comprehend due to illness severity or cognitive limitations, consent may be obtained from a legal guardian or family member, with subsequent confirmation of consent by the patient once their condition improves.\n\nExclusion Criteria:\n\n* Treatment-related: Patients who are currently receiving continuous positive airway pressure (CPAP) therapy for OSA.\n* Other Major Central Nervous System Disorders: Presence of other serious conditions that may significantly affect central nervous system function, aside from schizophrenia, such as major depressive disorder or bipolar disorder.\n* Severe Medical Illnesses: Including, but not limited to, malignant tumors, end-stage cardiopulmonary disease, neuromuscular disorders severely affecting motor or respiratory function, uncontrolled epileptic seizures, or other serious medical conditions that prevent patients from sleeping in the supine position.\n* Clinical Judgment: Patients deemed unsuitable for participation due to clinical conditions (e.g., agitation, non-cooperation, or other safety concerns).","70 Years",{"count":218,"type":20},80,"This research project aims to evaluate the prevalence of comorbid OSA and its impact on disease progression among hospitalized schizophrenia patients using non-wearable devices.",[221],"Schizophrenia and Schizophrenia Spectrum Psychosis",[223,224,225,226,227],"Schizophrenia","Sleep- Disordered Breathing","Obstructive Sleep Apnea","Non-Wearable Devices","Hospitalized Patients","2025-09-17",{"date":230,"type":42},"2025-09-25",{"date":232,"type":42},"2025-09-09",{"date":234,"type":20},"2026-04-30",{"name":48,"class":49},{"id":237,"slug":238,"hasResults":11,"nctId":239,"briefTitle":240,"officialTitle":240,"acronym":241,"eligibilityCriteria":242,"healthyVolunteers":130,"sex":16,"minAge":131,"maxAge":243,"enrollmentInfo":244,"targetDuration":4,"studyType":21,"phases":246,"briefSummary":247,"conditions":248,"keywords":251,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":263,"completionDateStruct":265,"leadSponsor":267,"locationsCount":50},"100606716","neurobiological-investigations-of-mindfulness-depression-and-sleep-disturbances-in-medical-staffs-and-community-elders-100606716","NCT07179172","Neurobiological Investigations of Mindfulness, Depression and Sleep Disturbances in Medical Staffs and Community Elders","NIMDS","Inclusion Criteria:\n\n1. Hospital staff aged 20-65 years, or elderly individuals aged 55-90 years.\n2. Individuals willing to participate in the entire mindfulness course and comply with study enrollment procedures.-\n\nExclusion Criteria:\n\n1. History of major neurological disorders (e.g., epilepsy, Parkinson's disease, stroke).\n2. History of major psychiatric disorders (e.g., schizophrenia, bipolar disorder).\n3. Use of medications that may affect sleep, other than illegal substances or sleeping pills.\n4. Individuals with metal implants.\n5. Individuals with claustrophobia.\n6. Pregnant women.\n7. History of alcohol or substance addiction.","90 Years",{"count":245,"type":20},40,[23],"The research team proposes a multi-year study with the first year focusing on the developmental phase. In this initial phase, we aim to recruit 40 participants (including healthcare staff and older adults) from Shuang-Ho Hospital and the surrounding community to undergo two mindfulness intervention sessions, each lasting four months. We anticipate that these interventions will prevent and alleviate stress and depressive symptoms while enhancing self-awareness and psychological health.",[249,250],"Sleep Disturbances","Depression",[252,253,254,255,256,257,258,259,260],"Medical personnel","sleep","depression","mental health","preventive medicine","mindfulness","aging","functional magnetic resonance imaging (fMRI)","wearable device","2025-09-10",{"date":228,"type":42},{"date":264,"type":42},"2025-06-14",{"date":266,"type":20},"2025-11-08",{"name":48,"class":49},{"id":269,"slug":270,"hasResults":11,"nctId":271,"briefTitle":272,"officialTitle":273,"acronym":4,"eligibilityCriteria":274,"healthyVolunteers":11,"sex":16,"minAge":275,"maxAge":276,"enrollmentInfo":277,"targetDuration":4,"studyType":21,"phases":278,"briefSummary":279,"conditions":280,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":283,"lastUpdatePostDateStruct":284,"startDateStruct":286,"completionDateStruct":288,"leadSponsor":289,"locationsCount":290},"100564981","prebiotic-effects-of-mulberry-fruit-in-children-and-adolescents-with-atopic-dermatitis-100564981","NCT06636240","Prebiotic Effects of Mulberry Fruit in Children and Adolescents With Atopic Dermatitis","Study on the Potential Prebiotic Effects and Gut Microbiota Changes of Glucoside-enriched Mulberry Fruit in Children and Adolescents With Atopic Dermatitis","Inclusion Criteria:\n\n* Aged 6 years and above (including 6 years) to less than 18 years (excluding 18 years)\n* The legal guardian has the ability to understand and is willing to sign the written informed consent document\n* Diagnosed by a physician according to the international Hanifin \\& Rajka criteria for atopic dermatitis, with a confirmed diagnosis of more than six months\n\nExclusion Criteria:\n\n* Allergic to berries, mulberries, fruits from the same family (such as figs), or similar chemical or biological components\n* Patients with immunodeficiency, including congenital or acquired immune disorders\n* Patients with immune-related diseases other than allergies, asthma, or allergic rhinitis, including malignancies, rheumatic diseases, lupus erythematosus, chronic liver diseases, cirrhosis, kidney diseases, diabetes, or asplenia\n* Individuals with other diseases or mental disorders that prevent them from complying with the intervention plan\n* Patients with Short Bowel Syndrome\n* Received oral or injectable antibiotics in the past month\n* Received immunomodulators, biologics, or oral\u002Finjectable steroids exceeding 2 mg\u002Fkg\u002Fday in the past three months\n* Underwent major surgery within 28 days before the study intervention (including the 28th day) or have not recovered from the side effects or complications of drug treatment\u002Fsurgery from four weeks prior\n* Currently participating in other drug intervention studies\n* Currently experiencing systemic infection or unexplained fever (ear temperature greater than or equal to 38°C)\n* Pregnancy\n* Premature infants (born before 37 weeks, excluding 37 weeks)\n* Individuals with congenital diseases, nutritional or metabolic disorders, or keratinization disorders\n* Diagnosed with malignancies within the past five years.","6 Years","17 Years",{"count":134,"type":20},[23],"This project proposes a randomized controlled human study to explore the prebiotic effects of consuming mulberry juice on atopic dermatitis in children and adolescents. The study aims to investigate the potential of mulberry fruit as a human prebiotic. This human study will recruit up to 120 participants from the Taipei Medical University Hospital (commissioned by the Ministry of Health and Welfare). Participants will be divided into experimental groups and a control group, with a 3-month intervention involving five clinical assessments and three stool collections. The goal is to compare the severity of atopic dermatitis, gut microbiota, and metabolite changes during the 6 days of mulberry juice consumption between the experimental and control groups.\n\nThis project will help establish mulberry fruit as a potential human prebiotic and adjunctive treatment for alleviating atopic dermatitis in children.",[281,282],"Atopic Dermatitis (Eczema)","Atopic Dermatitis, Probiotics","2025-05-20",{"date":285,"type":42},"2025-05-25",{"date":287,"type":42},"2025-03-17",{"date":234,"type":20},{"name":48,"class":49},2,{"id":292,"slug":293,"hasResults":11,"nctId":294,"briefTitle":295,"officialTitle":296,"acronym":4,"eligibilityCriteria":297,"healthyVolunteers":11,"sex":16,"minAge":298,"maxAge":299,"enrollmentInfo":300,"targetDuration":4,"studyType":21,"phases":302,"briefSummary":303,"conditions":304,"keywords":306,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":311,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":50},"100580487","aluminum-foil-reflector-on-phototherapy-for-newborn-with-jaundice-100580487","NCT06837935","Aluminum Foil Reflector on Phototherapy for Newborn with Jaundice","Effect of Aluminum Foil Reflector on Phototherapy for Newborn Infants with Unconjugated Hyperbilirubinemia: a Randomized Controlled Trial","Inclusion Criteria:\n\n1. Newborns who are admitted to the neonatal ward for examination and treatment due to jaundice levels reaching the treatment threshold.\n2. Term babies below 14 days of age (gestational age of 37 weeks or greater).\n3. No evidence of hemolysis\n\nExclusion Criteria:\n\n1. Infants with serum bilirubin levels close to the exchange transfusion limit\n2. Hemolytic disease (Ex: G6PD)\n3. Congenital anomalies\n4. Elevated direct bilirubin\n5. Infants with abnormal liver function or biliary structure\n6. Infants who receive Cardiopulmonary Resuscitation after birth or suspected perinatal asphyxia","1 Hour","14 Days",{"count":301,"type":20},160,[23],"Hyperbilirubinemia is defined as the presence of bilirubin in the serum of newborns at levels exceeding the normal range. It is the most common problem among healthy newborns, with an incidence of approximately 40% to 60% in full-term infants. The primary cause is the immature bilirubin metabolism in newborns, leading to the accumulation of excess bilirubin in the blood, which in turn results in a temporary yellowing of the skin and sclera, known as jaundice. Physiological jaundice in full-term newborns typically appears 24 to 72 hours after birth, peaking on days 4 to 5. Studies have shown that neonatal jaundice is a leading cause of readmission after discharge.\n\nPhototherapy is the most effective and safest treatment for neonatal hyperbilirubinemia. It takes advantage of bilirubin's sensitivity to light, converting bilirubin into water-soluble conjugated bilirubin, which is then excreted through bile and urine, thereby reducing total bilirubin levels. The most effective light during phototherapy has a wavelength of 400 nm to 520 nm and an intensity of at least 30 microW\u002Fcm²\u002Fnm, with at least 80% of the infant's body surface area exposed.\n\nThis study aims to investigate whether using aluminum foil reflective covering around the phototherapy incubator can enhance the effectiveness of light treatment for jaundice in infants, thus potentially reducing the duration of phototherapy required.",[305],"Newborn Jaundice",[307,308,309,310],"Aluminum Foil Reflector","Phototherapy","Newborn","Hyperbilirubinemia","2025-03-23",{"date":313,"type":42},"2025-03-26",{"date":315,"type":20},"2025-05-01",{"date":317,"type":20},"2026-12-31",{"name":48,"class":49},{"id":320,"slug":321,"hasResults":11,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":326,"targetDuration":4,"studyType":21,"phases":327,"briefSummary":328,"conditions":329,"keywords":333,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":337,"lastUpdatePostDateStruct":338,"startDateStruct":340,"completionDateStruct":342,"leadSponsor":344,"locationsCount":50},"100576923","the-impact-of-social-media-delivered-chemotherapy-side-effects-education-for-breast-cancer-patients-receiving-chemotherapy-100576923","NCT06791603","The Impact of Social Media-delivered Chemotherapy Side Effects Education for Breast Cancer Patients Receiving Chemotherapy","The Impact of Social Media-delivered Chemotherapy-related Side Effects Education for Breast Cancer Patients Receiving First Time Chemotherapy","Inclusion Criteria:\n\n* Breast cancer patients aged 18 or older undergoing their first chemotherapy.\n* Possess a smartphone and are able to watch videos on it.\n\nExclusion Criteria:\n\n* Unable to read or complete questionnaires in Chinese.\n* Cognitive impairments.\n* Pregnant women.",{"count":108,"type":20},[23],"The goal of this clinical trial is to learn if a standardized pharmacists-provided education module by social media can improve patients' knowledge of chemotherapy-related side effects. The main questions it aims to answer is:\n\n• Do patients who received a standardized pharmacists-provided education module by social media improve their knowledge of chemotherapy-related side effects? Researchers will compare standardized chemotherapy education +video (experimental group) versus chemotherapy handouts (control group).\n\nParticipants will:\n\n* Received standardized chemotherapy education + video or chemotherapy handouts at the first and second chemotherapy section.\n* Fill out a questionnaire for outcomes assessment.",[330,331,332],"Chemotherapy Side Effects","Social Media","Education of Patients",[334,335,336],"pharmacist","chemotherapy education","social media","2025-01-22",{"date":339,"type":42},"2025-01-24",{"date":341,"type":42},"2025-01-06",{"date":343,"type":20},"2026-01-31",{"name":48,"class":49},{"id":346,"slug":347,"hasResults":11,"nctId":348,"briefTitle":349,"officialTitle":350,"acronym":4,"eligibilityCriteria":351,"healthyVolunteers":11,"sex":16,"minAge":275,"maxAge":4,"enrollmentInfo":4,"targetDuration":4,"studyType":352,"phases":4,"briefSummary":353,"conditions":354,"keywords":4,"overallStatus":356,"whyStopped":4,"lastUpdateSubmitDate":357,"lastUpdatePostDateStruct":358,"startDateStruct":4,"completionDateStruct":4,"leadSponsor":360,"locationsCount":50},"100511132","a-preliminary-study-on-digital-learning-aids-for-special-children-with-triz-and-3d-printing-technology-100511132","NCT05935462","A Preliminary Study on Digital Learning Aids for Special Children With TRIZ and 3D Printing Technology","A Preliminary Study on the Demand and Design of Digital Learning Aids for Special Children With TRIZ and 3D Printing Technology","Inclusion Criteria:\n\nAnalysis of Systematic Questionnaires part\n\n* the caregiver of a child with special needs in early care;\n* the caregiver or child has trouble using electronic devices or needs;\n* the child can cooperate with the full questionnaire;\n* the child with special needs in early care attends school. Analysis of Assistive Device Trial part\n* Special children aged 6 to 9 years who are currently receiving early intervention;\n* Children who experience difficulties or have needs related to using electronic devices;\n* Participants who are able to complete the trial sessions;\n* Special children receiving early intervention who are attending school.\n\nExclusion Criteria:\n\nAnalysis of Systematic Questionnaires part\n\n* The child is younger than 4.5 years old or older than 9 years old;\n* The caregiver is unable to communicate and read in Chinese.\n\nAnalysis of Assistive Device Trial part\n\n* Children younger than 6 years or older than 9 years of age;\n* Children who are unable to recognize Zhuyin (Bopomofo) phonetic symbols.","EXPANDED_ACCESS","During the transition phase from early intervention to primary education (4.5 years to 8.11 years), children with special needs may encounter difficulties in using digital learning media. The investigators intend to apply the TRIZ analysis method to enhance children's participation in learning. Additionally, the investigators plan to design a preliminary model of learning aids and conduct a trial.",[355],"Digital Learning Aids for Special Children","AVAILABLE","2024-12-10",{"date":359,"type":42},"2024-12-16",{"name":48,"class":49},{"id":362,"slug":363,"hasResults":11,"nctId":364,"briefTitle":365,"officialTitle":366,"acronym":4,"eligibilityCriteria":367,"healthyVolunteers":11,"sex":16,"minAge":131,"maxAge":368,"enrollmentInfo":369,"targetDuration":4,"studyType":21,"phases":371,"briefSummary":372,"conditions":373,"keywords":376,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":379,"lastUpdatePostDateStruct":380,"startDateStruct":382,"completionDateStruct":384,"leadSponsor":386,"locationsCount":4},"100526235","using-digitalized-incentive-spirometers-to-assist-postoperative-rehabilitation-of-abdominal-surgery-patients-100526235","NCT06132100","Using Digitalized Incentive Spirometers to Assist Postoperative Rehabilitation of Abdominal Surgery Patients","Using Wireless Transformation of Portable Three-ball Incentive Spirometers to Assist the Record of Postoperative Rehabilitation and Pulmonary Function Change in Patients Undergoing Abdominal Surgery","Inclusion Criteria:\n\n* 1\\. Patients undergoing bariatric surgery\n* 2\\. Patients could cooperate with conducting incentive spirometry before and after the operation.\n\nExclusion Criteria:\n\n* 1\\. Patients with contra-indication for incentive spirometry.\n* 2\\. Patients could not deeply breathe with pulmonary vital capacity less than 10mL\u002Fkg.\n* 3\\. Patients could not cooperate with conducting incentive spirometry before and after the operation.\n* 4\\. Other causes judged by the Principal Investigator","75 Years",{"count":370,"type":20},200,[23],"The purpose of this clinical trial is to use a digital recording device integrated with an incentive spirometer to record a patient's deep breathing lung training following abdominal surgery. Through this digital recording, it will be possible to effectively assess the daily frequency, duration, depth of deep breaths, and the volume of inhalation performed by the patient during their breathing exercises. This will transform the previously difficult-to-describe deep breathing training into a digital record, allowing healthcare professionals to quickly evaluate the patient's condition. Patients can also monitor their own respiratory function changes, leading to positive health promotion benefits, accelerating their postoperative recovery, and simultaneously reducing healthcare costs and improving medical quality.",[374,375],"Bariatric Surgery Candidate","Sleep Apnea, Obstructive",[377,378],"bariatric surgery","incentive spirometry","2023-11-14",{"date":381,"type":42},"2023-11-15",{"date":383,"type":20},"2023-12",{"date":385,"type":20},"2026-12",{"name":48,"class":49},{"id":388,"slug":389,"hasResults":11,"nctId":390,"briefTitle":391,"officialTitle":392,"acronym":393,"eligibilityCriteria":394,"healthyVolunteers":130,"sex":16,"minAge":395,"maxAge":243,"enrollmentInfo":396,"targetDuration":4,"studyType":21,"phases":398,"briefSummary":399,"conditions":400,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":401,"lastUpdatePostDateStruct":402,"startDateStruct":404,"completionDateStruct":406,"leadSponsor":407,"locationsCount":50},"100470591","taiwan-geriatric-study-for-dementia-risk-prevention-and-cognitive-enhancement-by-multi-modal-intervention-100470591","NCT05407857","Taiwan Geriatric Study for Dementia Risk Prevention and Cognitive Enhancement by Multi-modal Intervention","Taiwan Geriatric Study for Dementia Risk Prevention and Cognitive Enhancement by Multi-modal Intervention (TaiPEI)","TaiPEI","Inclusion Criteria:\n\n1. People over 60 without dementia\n2. Agree to join the study and sign the consent form\n3. The Modified Rankin Scale (MRS) scores between 0-1 points\n4. Education level: elementary or higher education (6 years) or can read and write Chinese\n5. Very early dementia screening scale (AD-8) \\\u003C 2, or more than 2 points but without dementia diagnoses after refer to a neurologist.\n6. Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) Risk Score: above 8; diagnosed with mild cognitive impairment (MCI) or subjective cognitive decline (SCD) in the past six months.\n\nExclusion Criteria:\n\n1. Have been diagnosed with any kind of dementia\n2. Suspected dementia patients or others who are not suitable to participate in the research assessed by a doctor at the first visit\n3. Diseases affecting the safety of various interventional activities (such as remaining life less than two years, symptomatic heart\u002Fcerebrovascular disease within 6 months, vascular reperfusion or reconstruction-related surgery within one year, etc., malignant tumor within one year)\n4. Severe blindness, hearing or communication impairment, or other difficulty in cooperating or completing assessments and interventions (especially exercise) in the study\n5. Severe mental illnesses, including major depression disorder, or major neuromusculoskeletal disorders that are not suitable to join the study.\n6. Drug or alcohol abuse in the last year\n7. Overlapping with other interventional trials at the same time which may affect the evaluation results.","60 Years",{"count":397,"type":20},380,[23],"A 3-arm randomized controlled trial of multi-modal non-pharmacological Intervention for preventing the risk of dementia in Taiwanese geriatric people",[199],"2022-10-27",{"date":403,"type":42},"2022-10-28",{"date":405,"type":42},"2022-07-01",{"date":385,"type":20},{"name":48,"class":49},""]