[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Teachers College, Columbia University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":242},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,8,0,[8,55,86,116,141,169,192,214],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":37,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100595742","phase-2-comparing-traditional-semantic-feature-analysis-tsfa-and-semantic-feature-analysis--metacognitive-strategy-training-sfamst-100595742",false,"NCT07036406","Comparing Traditional Semantic Feature Analysis (tSFA) and Semantic Feature Analysis + Metacognitive Strategy Training (SFA+MST)","Comparing the Effectiveness of Traditional Semantic Feature Analysis (SFA) Versus SFA Plus Metacognitive Strategy Training (SFA+MST) for People With Acquired Aphasia","Inclusion Criteria:\n\n* Have aphasia due to a single acute event (e.g., left-hemisphere stroke, traumatic brain injury)\n* Be at least six-months post aphasia-onset,\n* Be a proficient English speaker,\n* Have normal or corrected to normal hearing (i.e., hearing aids) and vision (i.e., eyeglasses),\n* Have no history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug\u002Falcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems\n\nExclusion Criteria:\n\n* A history of neurodegenerative disease (e.g., dementia), severe motor speech disorder, significant mental illness, psychiatric disorder, drug\u002Falcohol abuse, or neurological condition that could influence their cognitive, language, and memory systems,\n* Children under the age of 18,\n* Adults over the age of 89,\n* Uncorrected hearing and vision.","ALL","18 Years","89 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The goal of this clinical trial is to compare the effectiveness of traditional Semantic Feature Analysis (SFA) treatment to a modified SFA protocol that includes Metacognitive Strategy Training (SFA+MST) for adults with acquired aphasia. The main questions it aims to answer are:\n\n* What are the comparative outcomes in picture naming accuracy and strategy use during picture naming following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia?\n* What are the comparative outcomes in percent of informative content and rate of informative content during spontaneous speech production following 2 months of traditional SFA versus SFA + MST in adults with acquired aphasia?\n\nResearchers will compare outcomes between these two treatments to see if SFA+MST yields larger effects in picture naming and spontaneous speech outcomes than traditional SFA.\n\nParticipants will complete:\n\n* 5-7 pre-treatment assessment sessions where they will be asked to name pictures, tell stories\u002Fdescribe pictures, answer questions, and complete questionnaires,\n* 3 treatment sessions of SFA \\*OR\\* SFA+MST per week for 8 weeks, for a total of 24 sessions,\n* 7 weekly probes (i.e., short, intermittent assessments throughout the treatment phase),\n* 3 post-treatment assessment sessions immediately after treatment ends, where they will complete the same assessment tasks as they did pre-treatment (e.g., naming pictures, telling stories, etc.),\n* 2 retention assessment sessions, one 30 days and the other 60 days following the final treatment session, where they will be asked to name pictures, tell stories\u002Fdescribe pictures, and describe what they learned during the study.",[27,28,29,30,31,32,33,34,35,36],"Aphasia","Aphasia Following Cerebral Infarction","Aphasia, Acquired","Aphasia, Rehabilitation","Aphasia, Anomic","Aphasia, Broca","Aphasia, Conduction","Aphasia, Expressive","Aphasia Non Fluent","Aphasia, Mixed",[27,38,39,40,41],"Anomia","Stroke","Communication","Language","RECRUITING","2026-06-23",{"date":45,"type":46},"2026-06-25","ACTUAL",{"date":48,"type":46},"2025-07-28",{"date":50,"type":21},"2027-07",{"name":52,"class":53},"Teachers College, Columbia University","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":4,"eligibilityCriteria":61,"healthyVolunteers":11,"sex":16,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":4,"studyType":22,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":54},"100630489","habit-ile--fst-in-children-with-sma-preliminary-effectiveness-100630489","NCT07488338","HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness","Feasibility and Preliminary Effectiveness of HABIT-ILE + Functional Strength Training in Children With Spinal Muscular Atrophy (SMA): a Prospective Single-group Intervention Trial.","Inclusion Criteria:\n\n* Have a confirmed SMA diagnosis\n* Be 5-17 years old\n* Complete all pre- and post-intervention assessments\n* Understand and speak English\n* Follow instructions without major cognitive or behavioral issues\n* Have received a stable disease-modifying therapy (DMT) dose for ≥6 months\n* Be classified as a sitter or walker (SMA type 2 or 3) with supported standing ability (score ≥1 on Item 18 of the HFMSE) without KAFOs, AFOs, or external standing devices\n\nExclusion Criteria:\n\n* Orthopedic surgery within the past year\n* New pharmaceutical treatment during the study\n* Concurrent participation in another clinical trial","5 Years","17 Years",{"count":65,"type":21},20,[67],"NA","This single-arm pilot study will assess the preliminary effectiveness of an intensive motor skill intervention (HABIT-ILE) combined with functional strength training (FST) in children with SMA who are receiving disease-modifying therapies. Participants will attend a HABIT-ILE + FST summer camp for 6 hours per day over a 3-week period, totaling 90 hours of training.",[70],"Spinal Muscular Atrophy (SMA)",[72,73,74,75,76,77],"HABIT-ILE","Functional Strenght Training","Pediatric","Rehabilitation","Motor control","Intensive","2026-03-18",{"date":80,"type":46},"2026-03-23",{"date":82,"type":21},"2026-03-15",{"date":84,"type":21},"2028-12-31",{"name":52,"class":53},{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":4,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":104,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":111,"completionDateStruct":113,"leadSponsor":115,"locationsCount":54},"100629724","readiness-and-progress-in-emotion-regulation-therapy-100629724","NCT07478393","Readiness and Progress in Emotion Regulation Therapy","Inclusion Criteria:\n\n* Between the ages of 18 and 65\n* Fluent in English (and therefore able to provide consent)\n* Currently living in New York State\n* Access to at least one device with internet and video-conferencing capabilities\n* High self-reported worry, rumination, and\u002For self-criticism\n* Meet Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) criteria for at least one, current psychological disorder\n\nExclusion Criteria:\n\n* Active suicidal ideation or intent\n* Substance dependence disorder, schizophrenia, bipolar-I disorder, or a primary DSM-5 diagnosis of borderline or narcissistic personality disorder\n* Currently in therapy or receiving any type of psychosocial treatment\n* Individuals taking psychotropic mediation that has not been stabilized for a period of at least 3 months\n* Current students at Teachers College, Columbia University","65 Years",{"count":94,"type":21},36,[67],"This study is an open trial designed to examine individual changes that occur before, during, and after 6 modules of Emotion Regulation Therapy (ERT) delivered via telehealth for individuals in New York State who are experiencing elevated worry, rumination, or self-criticism.",[98,99,100,101,102,103],"Rumination","Worry","Self-Criticism","Anxiety","Depression","Distress, Emotional",[99,98,100,105,106,107],"Emotion Regulation Therapy","Emotion Regulation","Treatment Mechanisms","2026-03-12",{"date":110,"type":46},"2026-03-17",{"date":112,"type":46},"2025-10-24",{"date":114,"type":21},"2028-09-01",{"name":52,"class":53},{"id":117,"slug":118,"hasResults":11,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":4,"eligibilityCriteria":122,"healthyVolunteers":11,"sex":16,"minAge":123,"maxAge":124,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},"100493105","phase-2-rehabilitation-of-airway-protection-in-parkinsons-disease-100493105","NCT05700825","Rehabilitation of Airway Protection in Parkinson's Disease","Rehabilitation of Airway Protection in Parkinson's Disease: Comparing In-person and Telehealth Service Delivery Models","Inclusion criteria:\n\n* Diagnosed with PD (Hoehn and Yahr Stages II-IV)126,127 confirmed by a Movement Disorders fellowship trained neurologist having reviewed the video recorded Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) assessment for each participant and using strict UK brain bank criteria\n* airway protective deficits as defined as a minimum of penetration of thin liquids (penetration-aspiration score\\>3) as determined by instrumental swallowing assessment and\u002For dystussia as determined by voluntary cough assessment (PEFR ≤4.1 L\u002Fs)\n* not actively receiving exercise-based swallowing therapy\n* between the ages of 50 and 90.\n\nExclusion criteria:\n\n* Other neurological disorders (e.g., multiple sclerosis, stroke, brain tumor, etc.)\n* history of head and neck cancer\n* history of breathing disorders or diseases (e.g., COPD)\n* history of smoking in the last five years\n* uncontrolled hypertension\n* difficulty complying due to neuropsychological dysfunction (i.e., severe depression with \\>28 on the Beck Depression Index (BDI-II), dementia with \\\u003C19 on the Montreal Cognitive Assessment (MoCA))\n* allergy to capsaicin or barium\n* further than 1.5 hours (door to door) distance from either Teachers College, Columbia University or Purdue University.","50 Years","90 Years",{"count":126,"type":21},120,[24],"Airway protective disorders are a prevalent and progressive consequence of Parkinson's Disease (PD), and often result in aspiration pneumonia which is the leading cause of death in PD. Despite this, a large number of patients with PD do not access specialized services to address these critical deficits. The investigators will examine the comparative effectiveness of a novel treatment paradigm delivered in-person versus via telehealth in persons with PD, as well as the role of patient burden and treatment adherence on outcomes; thus, the proposed research is relevant to public health and in line with NIH's mission to identify novel, efficacious, and accessible rehabilitation strategies for short- and long-term improvement of dysfunctional airway protection in PD.",[130,131],"Parkinson Disease","Dysphagia","2025-09-19",{"date":134,"type":46},"2025-09-24",{"date":136,"type":46},"2022-08-11",{"date":138,"type":21},"2027-09-01",{"name":52,"class":53},2,{"id":142,"slug":143,"hasResults":11,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":148,"sex":16,"minAge":149,"maxAge":92,"enrollmentInfo":150,"targetDuration":4,"studyType":152,"phases":4,"briefSummary":153,"conditions":154,"keywords":159,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":54},"100527865","school-violence-exposure-as-an-adverse-childhood-experience-100527865","NCT06153316","School Violence Exposure as an Adverse Childhood Experience","School Violence Exposure as an Adverse Childhood Experience: a Nationwide Study of K- 12 School Responses to Violence and Their Impact on Youth Mental Health and Educational Outcomes","School-level Inclusion criteria:\n\nFor a school to be considered for participation, it should meet all the following criteria:\n\n1. The school must consent to participate in the study.\n2. Gun shooting incident\n\n   * For exposure schools: Must have experienced a gun shooting incident between 1\u002F1\u002F2015-12\u002F31\u002F2022 .\n   * For non-exposure schools: there should not have been a gun shooting incident between 1\u002F1\u002F2011-12\u002F31\u002F2022.\n3. Must have the student population of interest that is middle through grade 12, and-\n\n   * For exposure schools: At least one grade that experienced the shooting should still be studying at the school.\n   * For non-exposure schools: must have the same grade levels as the pair-matched case school and none of them should have been exposed to any gun shooting incident at that school.\n4. Must be a public school.\n\n   * All non-public schools (e.g., private, charter, parochial schools) and schools outside of the middle-12 range (e.g. daycares, only elementary, preschools, and universities) are not eligible for the study.\n\nIndividual-level Inclusion Criteria:\n\nPrincipals: Must be the current Principal of the participating school. Teachers: Must be a current teacher at the participating school. Students: Must be a current student at the participating school studying in grades 6-12.",true,"11 Years",{"count":151,"type":21},2500,"OBSERVATIONAL","This study hypothesize that school safety strategies may contribute to poor mental health and distress among various school populations and proposes the following research questions to be answered through this study:\n\n1. Is there a significant difference in the prevalence of mental health outcomes, perceived school safety, and academic engagement between early adolescent and adolescent students (grades 6 - 12) at schools that have experienced a school shooting and those that have not?\n2. Are existing interventions to promote school safety and security associated with poor mental health outcomes among students and school staff?\n3. Does the strength of this association between school safety interventions and mental health outcomes differ among students and teachers in those schools who have experienced a school shooting versus among students and teachers in those schools who never experienced a school shooting? And, among our sample of students, are these associations moderated by their ACE history? Participants will be asked to self-report data on their mental health and wellness, and perceived school safety through a survey.\n\nResearchers will compare the surveys from the participants from exposure schools (those who experienced a gun shooting incident) with surveys from the participants from non-exposure schools (those who have not experienced a gun shooting incident)",[155,156,157,158],"Mental Health Outcomes","Adverse Childhood Experiences","Perceived School Safety","Educational Outcomes",[160],"School gun violence, School safety, mental health, ACEs","2025-09-09",{"date":163,"type":46},"2025-09-16",{"date":165,"type":46},"2024-04-26",{"date":167,"type":21},"2025-12",{"name":52,"class":53},{"id":170,"slug":171,"hasResults":11,"nctId":172,"briefTitle":173,"officialTitle":174,"acronym":4,"eligibilityCriteria":175,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":92,"enrollmentInfo":176,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":179,"conditions":180,"keywords":182,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":191,"locationsCount":54},"100499169","brief-interventions-for-coping-with-distress-100499169","NCT05779761","Brief Interventions for Coping with Distress","A Randomized Controlled Trial of Brief Interventions for Coping with Distress","Inclusion Criteria:\n\n* Between the ages of 18 and 65\n* Fluent in English (and therefore able to provide consent)\n* Currently living in New York City\n* Access to a smartphone and the internet\n* High self-reported worry, rumination, and\u002For self-criticism\n* Meet Diagnostic and Statistical Manual of Mental Disorders - Fifth Edition (DSM-5) criteria for at least one, current psychological disorder\n\nExclusion Criteria:\n\n* Active suicidal ideation or intent\n* Substance dependence disorder, schizophrenia, bipolar-I disorder, or a primary DSM-5 diagnosis of borderline or narcissistic personality disorder\n* Individuals currently receiving therapy or psychosocial treatment who do not plan to continue with the same treatment throughout the study period\n* Individuals taking psychotropic mediation that has not been stabilized for a period of at least 3 months\n* Current students at Teachers College, Columbia University\n* Individuals with cardiac conditions, diagnosed hyperhidrosis, and traumatic brain injuries or other neurological conditions (e.g., dementia, Parkinson's, epilepsy)",{"count":177,"type":21},180,[67],"This study is being done to compare the effectiveness of three different skills trainings to cope with distress. These three trainings are: 1) an attention skills training, 2) an attention and reflective thought skills training, and 3) a health and wellness education training.",[103,181,101,102],"Emotional Dysfunction",[106,183,101,102,99,98,100,184],"Distress Disorders","Skills Training","2024-11-18",{"date":187,"type":46},"2024-11-21",{"date":189,"type":46},"2023-05-12",{"date":167,"type":21},{"name":52,"class":53},{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":123,"maxAge":199,"enrollmentInfo":200,"targetDuration":4,"studyType":22,"phases":202,"briefSummary":204,"conditions":205,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":54},"100557659","early-phase-1-noise-augmented-automatic-speech-recognition-for-speech-treatment-in-parkinsons-disease-100557659","NCT06540989","Noise-augmented Automatic Speech Recognition for Speech Treatment in Parkinson's Disease","Understand Me for Life: Using Noise-augmented Automatic Speech Recognition to Improve Intelligibility in Parkinson's Disease","Inclusion Criteria:\n\n* Participants will qualify for the study if:\n\n  * They are 50-80 years old,\n  * They have a medical diagnosis of PD,\n  * They are within stages I-IV of Hoehn \\& Yahr Scale,\n  * Their antiparkinsonian medication schedule is stable,\n  * They present with mild to moderate dysarthria,\n  * They score ≥ 25 in the MMSE,\n  * They score ≤ 24 in the BDI-III.\n\nExclusion Criteria:\n\n* Participants will be excluded from the study if they:\n\n  * Present with atypical parkinsonism at the time of screening (or other neurological condition),\n  * Underwent neurosurgery treatment (DBS),\n  * Received intensive voice-focused treatment less than three months prior to their involvement in the current study,\n  * Present with any speech or voice pathology that is unrelated to PD.","80 Years",{"count":201,"type":21},42,[203],"EARLY_PHASE1","The goal of this clinical trial is to learn whether noise-augmented feedback using automatic speech recognition improves intelligibility and social participation in individuals with Parkinson's disease. The main questions the investigators will address are:\n\nDoes noise-augmented feedback lead to increased intelligibility, as measured by transcription accuracy scores?\n\nDoes a self-managed speech protocol lead to increased social participation, as measured by the Communicative Participation Item Bank and the Communicative Effectiveness Index questionnaires?\n\nParticipants will:\n\nReceive 2-4 initial speech assessments in-person in our lab. Engage in speech treatment sessions at home using their phone and computer four days a week for four weeks. Four of those sessions will be directly monitored online by a speech-language pathologist. The rest of the sessions are completed by the participant.\n\nCome to the lab for two post-treatment assessments following completion of treatment.\n\nCome to the lab six months after treatment completion for an additional assessment.",[130],"2024-08-13",{"date":208,"type":46},"2024-08-15",{"date":210,"type":21},"2024-09-01",{"date":212,"type":21},"2027-06-30",{"name":52,"class":53},{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":16,"minAge":221,"maxAge":63,"enrollmentInfo":222,"targetDuration":4,"studyType":22,"phases":224,"briefSummary":225,"conditions":226,"keywords":228,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":234,"lastUpdatePostDateStruct":235,"startDateStruct":237,"completionDateStruct":239,"leadSponsor":241,"locationsCount":140},"100431381","robotic-trust-postural-intervention-for-children-with-cerebral-palsy-100431381","NCT04897347","Robotic TruST-Postural Intervention for Children With Cerebral Palsy","Postural Control Intervention With the Robotic Trunk-Support-Trainer (TruST) in Children With Cerebral Palsy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 6-17 years\n* Diagnosis of Bilateral CP: diplegia, triplegia, or quadriplegia\n* Gross Motor Function Classification Systems-Expanded \\& Review (GMFCS) levels III or IV\n* Ability to sit 5s with trunk support between mid-ribs and pelvis (SATCo = 3-7)\n* Cognitive capacity to follow basic verbal instructions (i.e., \"do not put your hands on your lap\" or \"follow and reach the toy\")\n\nExclusion Criteria:\n\n* Absent head control (SATCo = 1)\n* Current medical illness unrelated to CP at the time of the study\n* Severe dyskinesia that prevents the child from maintaining sitting and recovering balance during reaching movements\n* History of recurrent seizures (daily) or drug-resistance epilepsy\n* Severe Spinal Deformities: scoliosis \\>40◦ and\u002For kyphosis \\>45◦\n* Spinal osteosynthesis or orthopedic surgery of spine, upper or lower extremities in the last 6 months\n* Severe spasticity of biceps\u002Ftriceps in both upper extremities (Modified Ashworth Scale = 4)\n* Local chemodenervation therapy in spastic muscles (e.g., botulinum toxin or phenol injections) in upper or lower extremities in the previous 3 months or planned during the study\n* Other major surgeries in the previous 6 months (if medically contraindicated)","6 Years",{"count":223,"type":21},82,[67],"The purpose of this study is to test the efficacy of a motor learning-based postural and reaching control intervention delivered with the robotic Trunk-Support-Trainer (TruST) compared to the same motor learning-based intervention delivered with Static Trunk Support Equipment in children with cerebral palsy (CP) classified as III and IV with the Gross Motor Function Classification System (GMFCS).",[227],"Cerebral Palsy",[229,230,231,232,233],"Posture","Reaching","Robotics","Motor Learning","Motor Control","2023-12-21",{"date":236,"type":46},"2023-12-22",{"date":238,"type":46},"2022-02-26",{"date":240,"type":21},"2027-06",{"name":52,"class":53},""]