[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Texas Scottish Rite Hospital for Children\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":191},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,50,73,101,123,146,168],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100559060","phase-2-evaluation-of-pain-management-after-surgery-when-using-exparel-in-the-pediatric-population-100559060",false,"NCT06559215","Evaluation of Pain Management After Surgery When Using Exparel in the Pediatric Population","Prospective Evaluation of Post-operative Pain Management Using Exparel in the Pediatric Population","Inclusion Criteria:\n\n* Must be aged 13+ years at time of surgery\n* Must present with injury requiring an isolated MPFL Reconstruction\n* Ability to provide assent, legally appointed representative available to provide informed consent\n\nExclusion Criteria:\n\n* Patient \\\u003C13 years old\n* Requires fracture repair or another non-standardized surgery\n* Any MPFL Reconstruction that requires the use of arthrotomy or a tibial tubercle osteotomy\n* Any lower extremity procedure that is not an isolated MPFL Reconstruction\n* Patient pregnancy\n* Inability to provide assent or legally appointed representative to provide informed consent\n* Prior history of hypersensitivity to Exparel or any local anesthesia\n* BMI ≥ 40","ALL","13 Years","21 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","The goal of this randomized clinical trial is to determine if administration of Exparel via local infiltration for medial patellofemoral ligament (MPFL) reconstruction procedures in pediatric orthopaedic sports medicine patients provides significant pain relief and decreased narcotic use. The main questions it aims to answer are:\n\n* Does Exparel significantly reduce Visual Analog Scale (VAS) pain scores and pain levels up to one week postoperatively?\n* Does Exparel significantly decrease narcotic use (number of pills taken) up to one week postoperatively?\n\nResearchers will compare the pain outcomes and narcotic use of patients who receive Exparel and Marcaine via local infiltration to those of patients who receive only Marcaine via local infiltration for their MPFL reconstruction surgery. The goal is to understand if there is a significant difference in patient pain outcomes and narcotic use outside the first 24 hours postoperatively.\n\nParticipants will:\n\n* receive either Exparel + Marcaine intraoperatively or Marcaine only intraoperatively during their MPFL reconstruction surgery\n* receive and complete questionnaires at postoperative days 1, 4, and 7 regarding their pain scores, levels, and outcomes, effective pain treatments, overall pain interference, narcotic use (number of pills taken), and overall pain treatment satisfaction\n* receive and complete secondary outcome measures of functional and psychological outcomes regarding their MPFL reconstruction surgery at postoperative day 1",[27,28,29,30],"Medial Patellofemoral Ligament (MPFL) Reconstruction","Sports Injuries in Children","Analgesia","Pain, Postoperative",[32,33,34,35,36],"Narcotic use","Postoperative pain management","MPFL reconstruction","Visual Analog Scale (VAS) pain scores","Multimodal pain management protocol","RECRUITING","2026-03-05",{"date":40,"type":41},"2026-03-09","ACTUAL",{"date":43,"type":41},"2025-12-01",{"date":45,"type":21},"2028-09",{"name":47,"class":48},"Texas Scottish Rite Hospital for Children","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":72,"locationsCount":49},"100559054","phase-2-evaluation-of-pain-management-after-surgery-when-using-nerve-blocks-in-the-pediatric-population-100559054","NCT06559137","Evaluation of Pain Management After Surgery When Using Nerve Blocks in the Pediatric Population","Prospective Evaluation of Post-operative Pain Management Using Peripheral Nerve Blocks in the Pediatric Population","Inclusion Criteria:\n\n* Must be aged 13+ years at time of surgery\n* Must present with injury requiring an ACLR procedure with a Bone Patellar Tendon Bone or Quadriceps graft\n* Ability to provide assent, legally appointed representative available to provide informed consent\n\nExclusion Criteria:\n\n* Patient \\\u003C13 years old\n* Requires fracture repair or another non-standardized surgery\n* Any ACLR that requires the use of a graft type other than Bone Patellar Tendon Bone or Quadriceps tendon\n* Any lower extremity procedure that is not primarily an ACLR\n* Patient pregnancy\n* Inability to provide assent or legally appointed representative to provide informed consent\n* Prior history of hypersensitivity to Ropivacaine or any local anesthesia\n* BMI ≥ 40",{"count":58,"type":21},160,[24],"The goal of this randomized clinical trial is to determine if single-shot ropivacaine peripheral nerve blocks (PNB - perineural injections) for anterior cruciate ligament (ACL) reconstruction procedures in pediatric orthopaedic sports medicine patients provides significant pain relief and decreased narcotic use. The main questions it aims to answer are:\n\n* Does ropivacaine significantly reduce Visual Analog Scale (VAS) pain scores and pain levels up to one week postoperatively?\n* Does ropivacaine significantly decrease narcotic use (number of pills taken) up to one week postoperatively?\n\nResearchers will compare the pain outcomes and narcotic use of participants who receive a single-shot ropivacaine peripheral nerve block to those of participants who do not receive a single-shot ropivacaine peripheral nerve block for their ACL reconstruction surgery. The goal is to understand if there is a significant difference in participant pain outcomes and narcotic use outside the first 24 hours postoperatively.\n\nParticipants will:\n\n* receive either a single-shot ropivacaine peripheral nerve block intraoperatively or no peripheral nerve block during their ACL Quadriceps tendon graft or bone patellar tendon bone graft reconstruction surgery.\n* receive and complete questionnaires at postoperative days 1, 4, and 7 regarding their pain scores, levels, and outcomes, effective pain treatments, overall pain interference, narcotic use (number of pills taken), and overall pain treatment satisfaction\n* receive and complete secondary outcome measures of functional and psychological outcomes regarding their ACL reconstruction surgery at postoperative day 1",[62,28,29,30],"Anterior Cruciate Ligament (ACL) Tear",[32,33,64,35,36],"ACL reconstruction","NOT_YET_RECRUITING","2025-09-09",{"date":68,"type":41},"2025-09-16",{"date":70,"type":21},"2025-09",{"date":45,"type":21},{"name":47,"class":48},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":86,"conditions":87,"keywords":90,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":49},"100519213","implementation-of-therapy-together-100519213","NCT06040619","Implementation of Therapy Together","Implementation of Therapy Together With the State of Texas Early Childhood Intervention Program","Inclusion Criteria:\n\n* at risk for developing cerebral palsy or have been diagnosed with cerebral palsy\n* children ages 3 months to 5 years 11 months\n* present with asymmetric hand use\n* present with a unilateral upper limb impairment\n* able to visually attend to objects\n* demonstrate an interest in objects\n* attempt to reach for or grasp objects with the impaired upper extremity\n\nExclusion Criteria:\n\n* uncontrolled epilepsy\n* significant visual impairment\n* severe behavioral problems\n* inability to complete the assessment protocol.","3 Months","71 Months",{"count":83,"type":21},30,[85],"NA","The goal of this clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy. The main question\\[s\\] it aims to answer are:\n\n* Is the Therapy Together program effective in improving hand function and occupational performance compared to usual care?\n* Is it feasible to implement the Therapy Together program within the standard care, early intervention framework?\n\nParticipants will participate in an 8-week pediatric constraint-induced movement therapy program. Researchers will compare the group completing the Therapy Together Program to a group that is receiving usual care to see if there is a difference in the change in hand function, occupational performance, and development.",[88,89],"Cerebral Palsy","Hemiplegic Cerebral Palsy",[91,92],"constraint induced movement therapy","caregiver coaching","2025-09-04",{"date":95,"type":41},"2025-09-11",{"date":97,"type":41},"2023-11-13",{"date":99,"type":21},"2026-08",{"name":47,"class":48},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":22,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":120,"completionDateStruct":121,"leadSponsor":122,"locationsCount":49},"100600573","cervico-vestibular-home-exercise-program-feasibility-100600573","NCT07099248","Cervico-vestibular Home Exercise Program Feasibility","Feasibility and Acceptability of a Cervico-vestibular Home Exercise Program Following Concussion in Children","Concussion HEP","Inclusion Criteria:\n\n1. Patients \\\u003C18 years old\n2. Presenting to clinic ≤1 month after injury\n3. Diagnosed with a concussion at their clinic visit\n4. Have a total symptom score of 3 or more on the PCSI\n5. Visual acuity\u002Fhearing adequate for testing\n6. Parent\u002Fpatient must be fluent in English\n7. Ability to provide assent, Legally Appointed Representative available to provide informed consent\n\nExclusion Criteria:\n\n1. Patients ≥18 years old\n2. Moderate and severe TBI\n3. History of seizures\n4. History of \\>3 prior concussions\n5. History of chronic headaches\u002Fmigraines\n6. Presenting to clinic \\>1 month after injury","17 Years",{"count":83,"type":21},[85],"The purpose of this pilot study is to:\n\n1. Determine the feasibility of adherence to completing the home cervico-vestibular exercise program following concussion.\n2. Investigate the acceptability of the cervico-vestibular home exercise program.\n3. Investigate the impact of the cervico-vestibular home exercise program on symptom reduction, return to play, and return to learn\n4. Analyze the timing at which a home exercise program is typically prescribed.\n\nParticipants will be asked to do and keep track of exercises made to help in their concussion recovery over a two-week period. Participants will come back to see their doctor and complete surveys about how easy the exercises were to do and if they liked them.",[114,28],"Concussion",[114,116],"Home Exercise Program","2025-07-25",{"date":119,"type":41},"2025-08-01",{"date":70,"type":21},{"date":99,"type":21},{"name":47,"class":48},{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":127,"acronym":4,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":129,"enrollmentInfo":130,"targetDuration":4,"studyType":132,"phases":4,"briefSummary":133,"conditions":134,"keywords":136,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":141,"completionDateStruct":143,"leadSponsor":145,"locationsCount":49},"100228877","prospective-evaluation-of-treatment-for-clubfoot-100228877","NCT02257229","Prospective Evaluation of Treatment for Clubfoot","Inclusion Criteria:\n\n* Patients with a diagnosis of clubfoot deformity\n* Spanish speaking patients will be eligible to participate in the study.\n\nExclusion Criteria:\n\n* All patients without a diagnosis of clubfoot","18 Years",{"count":131,"type":21},2500,"OBSERVATIONAL","Specific aim:\n\nTo evaluate the outcome of infants who undergo one of two nonsurgical treatment interventions",[135],"Clubfoot Deformity",[137],"Clubfoot, deformity, correction, management, gait","2025-04-30",{"date":140,"type":41},"2025-05-04",{"date":142,"type":4},"2005-08",{"date":144,"type":21},"2029-09",{"name":47,"class":48},{"id":147,"slug":148,"hasResults":11,"nctId":149,"briefTitle":150,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":16,"minAge":152,"maxAge":81,"enrollmentInfo":153,"targetDuration":4,"studyType":22,"phases":155,"briefSummary":156,"conditions":157,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":49},"100522484","school-readiness-in-preschool-aged-children-with-cerebral-palsy-100522484","NCT06083220","School Readiness in Preschool-Aged Children With Cerebral Palsy","Inclusion Criteria:\n\n* ages 3 years to 5 years 11 months\n* unilateral cerebral palsy\n* ability to visually attend to objects\n* demonstrates an interest in objects\n* attempt to reach for or grasp an item with the impaired upper extremity\n* English-speaking participants\n\nExclusion Criteria:\n\n* uncontrolled epilepsy\n* significant visual impairment\n* severe behavioral problems\n* inability to complete the assessment protocol","36 Months",{"count":154,"type":21},20,[85],"The goal of this feasibility and proof of concept study is to learn about the feasibility, acceptability, and impact of a school readiness program for preschool-aged children with unilateral cerebral palsy. The main question\\[s\\] it aims to answer are:\n\n1. Is it feasible to implement an intensive school readiness program for preschool-aged children with UCP?\n2. Is the program acceptable to the children and their caregivers?\n3. What is the impact of the program on school readiness?\n\nParticipants will complete two pre-intervention assessments, participate in an intensive, goal directed, school readiness program, and complete 1 post-intervention assessment.",[158,159],"Unilateral Cerebral Palsy","School Readiness","2025-04-07",{"date":162,"type":41},"2025-04-08",{"date":164,"type":41},"2023-12-12",{"date":166,"type":21},"2026-07",{"name":47,"class":48},{"id":169,"slug":170,"hasResults":11,"nctId":171,"briefTitle":172,"officialTitle":173,"acronym":4,"eligibilityCriteria":174,"healthyVolunteers":11,"sex":16,"minAge":175,"maxAge":109,"enrollmentInfo":176,"targetDuration":4,"studyType":22,"phases":178,"briefSummary":179,"conditions":180,"keywords":181,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":183,"lastUpdatePostDateStruct":184,"startDateStruct":186,"completionDateStruct":188,"leadSponsor":190,"locationsCount":49},"100519812","acceptability-and-efficacy-of-go-move-100519812","NCT06048419","Acceptability and Efficacy of GO MOVE","Acceptability and Efficacy of GO MOVE: A Mobile Health Technology for Youth With Unilateral Cerebral Palsy","Inclusion Criteria:\n\n* Inclusion criteria for participants to enroll in the study include a diagnosis of unilateral CP or a non-progressive brain lesion, injury, or trauma of the developing brain that presents with a unilateral upper limb motor impairment. GMFCS levels 1 or 2. MACS levels 1-3. Age 3-17 years old, ability to follow directions, ability to complete the assessment protocol, and the ability to access the GO MOVE webpage on a personal device. All ethnic\u002Fracial groups will be eligible to participate. The ability to participate in everyday activities without restriction from a physician throughout the duration of their participation in the study (does not have restrictions\u002Fcontraindications following a medical procedure).\n\nExclusion Criteria:\n\n* The study will exclude any patients with uncontrolled epilepsy or significant visual impairment. The study will exclude any patient with severe behavioral problems or the inability to complete the assessment protocol or home program.","3 Years",{"count":177,"type":21},50,[85],"The goal of this clinical trial is to learn about the acceptability and efficacy of Go Move, a mobile website developed to assist youth with unilateral cerebral palsy and their caregivers with setting goals and selecting exercises and activities to meet the goals. The main question\\[s\\] it aims to answer are:\n\n* Is Go Move accepted by youth with unilateral cerebral palsy and their caregivers?\n* Does Go Move support goal attainment for youth with unilateral cerebral palsy?\n\nParticipants will set up and participate in a goal-driven home program using the Go Move mobile website. Participants will spend 1 hour and 15 minutes per week for 6 weeks working on their home program and will complete pre-intervention and post-intervention assessments.",[88,89],[182],"home program","2025-03-06",{"date":185,"type":41},"2025-03-10",{"date":187,"type":41},"2024-02-20",{"date":189,"type":21},"2026-12",{"name":47,"class":48},""]