[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Texas Tech University Health Sciences Center, El Paso\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":99},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100636119","phase-4-extended-oral-antibiotic-prophylaxis-in-diabetic-fracture-patients-100636119",false,"NCT07561541","Extended Oral Antibiotic Prophylaxis in Diabetic Fracture Patients","Extended Oral Antibiotic Prophylaxis in Diabetic Patients With Lower Extremity Fracture: A Multicenter Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Low extremity fracture requiring surgical treatment\n* Uncontrolled diabetes (Hemoglobin A1c \\> 7.0 or random glucose \\> 200 mg\u002FdL)\n* Age 18 years or older\n* Able to provide informed consent\n* English or Spanish speaker\n\nExclusion Criteria:\n\n* Known allergy to prescribed antibiotic and pre-determined alternatives\n* Open fractures\n* Current infection requiring antibiotic treatment\n* Immunocompromised status (chemotherapy, immunosuppressant medications)\n* End-stage renal disease that medication dosing cannot be adjusted for\n* Pregnant or breast-feeding\n* Unable to comply with follow-up","ALL","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The goal of this clinical trial is to learn if taking an antibiotic pill for 7 days after surgery reduces the risk of wound infection in adults with poorly controlled diabetes who have surgery to fix a broken bone in the leg, ankle, or foot. It will also learn about the safety of the extended antibiotic course. The main questions it aims to answer are:\n\nDoes a 7-day antibiotic course after surgery lower the rate of wound infection within 90 days? What medical problems do participants have when taking the extended antibiotic course?\n\nResearchers will compare a 7-day course of an oral antibiotic (cefadroxil) to standard care (no additional antibiotics after surgery) to see if the extended course reduces infections.\n\nParticipants will:\n\nTake an antibiotic pill or receive standard care for 7 days after surgery Receive a phone call from the study team about 1 week after surgery Visit the clinic at 3 weeks, 6 weeks, and 3 months after surgery for checkups",[26,27,28],"Fracture Lower Leg","Diabetes","Fracture Fixation, Internal",[27,30,31],"Lower extremity fracture","Extended oral antibiotic prophylaxis","RECRUITING","2026-05-06",{"date":35,"type":36},"2026-05-08","ACTUAL",{"date":38,"type":36},"2026-04-01",{"date":40,"type":20},"2027-12-31",{"name":42,"class":43},"Texas Tech University Health Sciences Center, El Paso","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":4,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100517355","early-phase-1-does-nerve-block--oral-dexamethasone-reduce-recurrence-of-headache-within-72-hrs-100517355","NCT06016465","Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?","Does Nerve Block Plus Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hours Better Than Nerve Block Alone?","Inclusion Criteria:\n\n* Meet ICHD-3 Migraine Headache Criteria\n* Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2\n* Nerve block performed with bupivacaine 0.5%\n\nExclusion Criteria:\n\n* Head trauma\n* Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma)\n* Headache in the setting of viral syndrome\n* Chronically on steroids\n* Known allergy to dexamethasone\n* Unable to reach the patient by phone or text for follow-up\n* Gestational diabetes or other uncontrolled diabetes\n* Known to be immunocompromised","85 Years",{"count":53,"type":20},84,[55],"EARLY_PHASE1","For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.",[58],"Migraine",[60,61,62,63],"migraine headache","peripheral nerve block","dexamethasone","steroid treatment","2026-04-30",{"date":33,"type":36},{"date":67,"type":36},"2023-09-15",{"date":69,"type":20},"2028-01-30",{"name":42,"class":43},1,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":83,"phases":4,"briefSummary":84,"conditions":85,"keywords":88,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":71},"100412094","depth-of-maximal-ileal-insertion-during-retrograde-enteroscopy-with-tts-balloon-100412094","NCT04646083","Depth of Maximal Ileal Insertion During Retrograde Enteroscopy With TTS Balloon","Depth of Maximal Insertion During Retrograde Enteroscopy Using Colonoscopy With Through-the-scope Balloon Enteroscopy (NaviAid) Compared With Using the Standard Colonoscope Alone","NaviAid2","Inclusion Criteria:\n\n1. Sign Informed Consent Form\n2. Patients age between 18-90 years\n3. Patients in which retrograde enteroscopy is indicated for any of the following:\n\nabnormal video capsule endoscopy non-diagnostic upper and lower endoscopy obscure gastrointestinal bleeding iron deficiency anemia non-diagnostic upper endoscopy and abnormal CT Hemodynamically stable\n\nExclusion Criteria:\n\n1. Inability to sign Informed Consent Form\n2. Pregnancy and breast feeding\n3. Prior colon resection\n4. Patients with known strictures\n5. Patients with altered anatomy\n6. Inadequate bowel preparation.","90 Years",{"count":82,"type":20},100,"OBSERVATIONAL","Diagnostic modalities for the evaluation of small bowel pathology include video capsule endoscopy (VCE), antegrade and retrograde device-assisted enteroscopy, CT and MR enterography (1). Despite VCE being the first-line evaluation modality, it lacks interventional capability. Deep enteroscopy (DE) allows tissue sampling and other therapeutic interventions with real-time endoscopic assessment. DE is usually performed with specific endoscopes (balloon-assisted device or spiral overtube) making it time consuming and there is limited availability since special instruments and accessories are required.(1,2) The through-the-scope (TTS) balloon system consists of a balloon catheter designed for anchoring in the small bowel, inserted through the instrument channel of a standard colonoscope.(3) The catheter is advanced, the balloon is inflated and anchored in the small intestine and the endoscope slides over the guiding catheter to the inflated balloon. The most common indications for DE are obscure GI bleeding, iron deficiency anemia, abnormal capsule endoscopy and chronic diarrhea. As compared to spiral, single-or double-balloon enteroscopy, TTS (NaviAid, SMART Medical Systems Ltd, Ra'anana, Israel) is a simpler technique, which requires less investment in infrastructure. The balloon catheter is advanced blindly in front of a standard adult colonoscope as it bends around the curves of the small bowel. To prevent perforation\u002Ftrauma the catheter is fitted with a soft silicone tip which easily bends under pressure.\n\nInsertion depth can be calculated during the withdrawal of the enteroscope. The Aim of the study: To compare the depth of maximal ileal insertion between through-the-scope balloon enteroscopy (NaviAid) with enteroscopy using the adult colonoscope (Olympus CF-190) alone, in the same patient, in a prospective cohort at University Medical Center of El Paso, Texas.",[86,87],"Obscure Gastrointestinal Bleeding","Anemia, Iron Deficiency",[89,90],"retrograde enteroscopy","small bowel bleeding","2025-06-13",{"date":93,"type":36},"2025-06-18",{"date":95,"type":36},"2021-01-14",{"date":97,"type":20},"2025-12-31",{"name":42,"class":43},""]