[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Texas Woman's University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":143},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,73,101,122],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":4},"100635617","an-online-nurse-led-purpose-focused-group-program-for-adult-women-with-multiple-sclerosis-effects-on-meaning-and-quality-of-life-100635617",false,"NCT07555015","An Online Nurse-Led Purpose-Focused Group Program for Adult Women With Multiple Sclerosis: Effects on Meaning and Quality of Life","The Impact of a Nurse-Led Virtual Group Intervention on Purpose and Quality of Life in Adult Women With Multiple Sclerosis","Inclusion Criteria:\n\n* women\n* over the age of 18\n* a diagnosis of Multiple Sclerosis (Primary Progressive, Relapsing-Remitting, Secondary Progressive)\n* access to a device with internet capability as well as audio and video functions\n* comfortable reading, writing, and participating in group discussions in English\n\nExclusion Criteria:\n\n* currently enrolled (or have been enrolled within the last 4 weeks) of any similar group based intervention therapy (logotherapy, Acceptance and Commitment Therapy, or Cognitive Behavioral Therapy)","FEMALE","18 Years",{"count":19,"type":20},40,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to learn how a six-week, nurse-led virtual group program may affect meaning in life and quality of life in adult women living with Multiple Sclerosis (MS). Many people with MS describe changes in identity, purpose, and daily life. This study will help researchers understand whether a structured group program can support women as they explore meaning and purpose while living with MS.\n\nThe main questions this study aims to answer are:\n\n* How does the program affect how participants search for meaning in life?\n* How does it affect their sense of life purpose or direction?\n* How does it affect their overall quality of life?\n\nThis study uses a single-group design. All participants will take part in the six-week virtual group program. The program is led by a registered nurse and focuses on guided reflection, values exploration, and group discussion.\n\nParticipants will:\n\n* Attend one virtual group session each week for six weeks\n* Take part in guided discussions and reflection exercises\n* Complete three online surveys: one before the program begins, one at Week 3, and one after Week 6\n* Use a computer, tablet, or phone to join all virtual sessions\n\nThe surveys will ask about:\n\n* How participants search for meaning in their lives\n* How much purpose and direction they feel\n* Their physical and emotional quality of life\n\nThere are no medications, invasive procedures, or in-person visits in this study.",[26],"Multiple Sclerosis",[26,28,29,30,31,32,33,34,35,36],"Quality of Life","Meaning in Life","Nurse-led behavioral intervention","Purpose-building intervention","Meaning-centered intervention","virtual group intervention","Nurse-guided","Psychological adaptations","Purpose in life","NOT_YET_RECRUITING","2026-04-27",{"date":40,"type":41},"2026-05-01","ACTUAL",{"date":43,"type":20},"2026-06",{"date":45,"type":20},"2026-09",{"name":47,"class":48},"Texas Woman's University","OTHER",{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":72},"100540170","fall-risk-and-quality-of-life-in-individuals-with-cancer-treatment-related-peripheral-neuropathy-100540170","NCT06313359","Fall Risk and Quality of Life: in Individuals With Cancer Treatment Related Peripheral Neuropathy.","Fall Risk and Quality of Life: Influence of Dual Task Performance, Cognition, and Sensorimotor Variables in Individuals With Cancer Treatment Related Peripheral Neuropathy.","Inclusion Criteria:\n\nExperimental group\n\n* Individuals 18 years and older\n* diagnosed with non- CNS cancer who underwent treatment and presents with peripheral neuropathy symptoms.\n\nControl group\n\n* age (+\u002F- one year) and gender matched individuals\n* no diagnosed peripheral neuropathy\n* No diagnosed cognitive symptoms.\n\nExclusion Criteria:\n\n* Unable to follow two step commands.\n* Unable to ambulate x 50 feet independently without use of an assistive device.\n* Unable to use a phone to send text messages.\n* Diagnosis of diabetic peripheral neuropathy\n* Diagnosis of CNS cancer.\n* Unable to speak\u002Funderstand English",true,"ALL",{"count":19,"type":20},"OBSERVATIONAL","The purpose of this research is to examine the impact of peripheral neuropathy on fall risk and quality of life in people who had cancer and neuropathy from cancer treatments. The investigators are interested to find out if the participant have any difficulty with thinking, feeling, balancing, or moving around that will contribute to risk for falls or quality of life. Investigators are also interested to see if the participants have any difficulty with doing two activities at the same time, such as walking and texting.",[62],"Peripheral Neuropathy Due to Chemotherapy","RECRUITING","2025-09-02",{"date":66,"type":41},"2025-09-03",{"date":68,"type":41},"2024-03-30",{"date":70,"type":20},"2026-06-30",{"name":47,"class":48},1,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":4,"eligibilityCriteria":78,"healthyVolunteers":11,"sex":57,"minAge":79,"maxAge":4,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},"100594549","short-term-and-intermediate-term-effects-of-self-applied-joint-mobilization-versus-clinician-applied-joint-mobilization-in-addition-to-exercise-in-patients-with-knee-osteoarthritis-a-randomized-clinical-trial-100594549","NCT07020897","Short-term and Intermediate-term Effects of Self-applied Joint Mobilization Versus Clinician-applied Joint Mobilization in Addition to Exercise in Patients With Knee Osteoarthritis: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Meets National Institute for Health and care Excellence (NICE) criteria for knee osteoarthritis:\n* Age 45 years or older\n* Movement-related knee pain\n* No morning stiffness or morning stiffness \\\u003C 30 minutes\n* Knee flexion contracture (kFC) at least 1cm, measured by heel-height\n* Fluency in verbal and written English for completion of outcome measure and screening, and to take directions.\n* Able to attend all study-related appointments\n\nExclusion Criteria:\n\n* Assistive device required for ambulation\n* Systemic disease affecting joint function (diabetes, rheumatological disorders, etc)\n* Previous lower extremity joint replacement\n* Lower quarter surgery, injection, or therapy in the past year\n* Other functionally-limiting physical impairment of the lower quarter\n* Spine or lower extremity compensation claim (work, accident, etc)","45 Years",{"count":81,"type":20},24,[23],"The goal of this clinical trial is to learn if a combination of patient self-administered joint mobilization and exercise works to treat knee osteoarthritis in adults. The main questions it aims to answer are:\n\n* Does self-administered joint mobilization improve the ability to perform regular daily activities?\n* Does self-administered joint mobilization improve knee motion?\n* Does self-administered joint mobilization improve hip strength?\n\nResearchers will compare the program of self-administered joint mobilization to a joint mobilization administered by a physical therapist.\n\nParticipants will:\n\n* Attend 8-12 physical therapy clinic visits over 6 - 8 weeks\n* Perform home exercises\n* Visit the clinic 6 months later for a brief check-up",[85],"Knee Osteoarthritis",[87,88,89,90,91],"Knee flexion contracture","Knee osteoarthritis","Joint mobilization","Physical therapy","Hip abductor strength","2025-06-05",{"date":94,"type":41},"2025-06-13",{"date":96,"type":20},"2025-07-15",{"date":98,"type":20},"2026-11-30",{"name":47,"class":48},2,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":56,"sex":57,"minAge":17,"maxAge":4,"enrollmentInfo":108,"targetDuration":4,"studyType":21,"phases":110,"briefSummary":111,"conditions":112,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":100},"100445008","benefits-of-insoles-with-real-time-alert-and-foot-self-care-education-100445008","NCT05074849","Benefits of Insoles With Real-Time Alert and Foot Self-Care Education","Benefits of Insoles With Real-Time Alert and Foot Self-Care Education in Improving Adherence for Prescribed Footwear in Patients With Diabetes Mellitus","Inclusion Criteria:\n\n* Men or women 18 years old or older,\n* Diagnosis of Diabetes Mellitus,\n* Ambulatory, Uses prescribed diabetes footwear.\n* Those willing and able to attend follow up visits such as long distance (i.e. greater than 30 miles to recruitment sites).\n* Those able to read or follow directions.\n\nExclusion Criteria:\n\n* Active Charcot Arthropathy or major foot deformity,\n* Cardiopulmonary disease (e.g. recent MI, Stroke),\n* Gangrene, active infection. Montreal Cognitive Assessment (MOCA\\\u003C20).\n* Wide spread malignancy or systemically immunocompromising disease.",{"count":109,"type":20},72,[23],"Novel approaches to promote adherence to diabetic footwear and prevent high incidence of diabetes foot ulcers are urgently needed. Investigators propose to translate an innovative and practical technology to supplement clinical and risk evaluation for patients with diabetes through wearable insoles and smart watch, along with foot self-care education, to improve adherence to prescribed footwear and reduce incidence of foot ulcers in those with diabetes and at risk for foot ulcers.",[113],"Diabetes Complications","2025-04-11",{"date":116,"type":41},"2025-04-16",{"date":118,"type":20},"2026-10-20",{"date":120,"type":20},"2026-12-30",{"name":47,"class":48},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":11,"sex":57,"minAge":17,"maxAge":4,"enrollmentInfo":128,"targetDuration":4,"studyType":21,"phases":130,"briefSummary":131,"conditions":132,"keywords":4,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":72},"100522922","behavioral-and-neural-correlates-of-post-stroke-fatigue-100522922","NCT06088914","Behavioral and Neural Correlates of Post-Stroke Fatigue","Inclusion Criteria:\n\n1. be at least 18 years old;\n2. have a history of unilateral stroke ≥ 3 months prior to enrollment to ensure stability;\n3. have an average score ≥ 4 on FSS;\n4. have some movement capability in the more affected arm (upper extremity Fugl-Meyer(FMUE) ≥ 28) to ensure they can perform the reaching task;\n5. be able to follow three-step commands.\n\nExclusion Criteria:\n\n1. acute medical problems;\n2. the presence of any contraindication to tDCS, MRI or TMS;\n3. the presence of significant depression (score \\> 10 on the Patient Health Questionnaire-9);\n4. significant pain in the upper extremities that interferes with movements; or\n5. use of medication which may affect the level of fatigue.",{"count":129,"type":20},32,[23],"The goal of this phase I\u002FII clinical trial is to determine the behavioral and neural effects of 5-daily transcranial direct current stimulation on post-stroke fatigue. The three aims are:\n\nAim 1: Investigate the behavioral effect of 5 daily sessions of anodal tDCS over the ipsilesional M1 on PSF.\n\nAim 2: Investigate the neurophysiological effect of 5 daily sessions of anodal tDCS over the ipsilesional M1.\n\nAim 3: Determine the relationship between changes in M1 excitability, brain connectivity and changes in PSF.\n\nParticipants will receive either a real or sham stimulation for 5 consecutive days and fatigue will be assessed before, immediately after and 1-month after the intervention. Fatigue will be assessed using clinical, behavioral, and neurophysiological outcomes.",[133,134],"Stroke","Fatigue","2024-10-14",{"date":137,"type":41},"2024-10-16",{"date":139,"type":41},"2023-12-15",{"date":141,"type":20},"2026-08-31",{"name":47,"class":48},""]