[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"The New York Proton Center\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100542393","patient-generated-health-data-collection-during-chemoradiotherapy-for-lung-cancer-100542393",false,"NCT06342284","Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer","Patient-Generated Health Data Collection During Chemoradiotherapy for Lung Cancer: A Pilot Study","PGHD","Inclusion Criteria:\n\n* Plan for fractionated (≥15 treatments) proton beam thoracic radiotherapy with curative intent for lung cancer\n* Non-small cell lung cancer (NSCLC) or small cell lung cancer (SCLC) histology is permitted.\n* Concurrent chemotherapy is permitted but not required..\n* Previous thoracic radiotherapy is allowed.\n* Ability to complete study surveys in English or Spanish\n* Age \\>\u002F= 18\n* Concurrent enrollment on other trials is permitted\n* Patients who already use wearable devices and\u002For smartphones that monitor physical activity are eligible for this trial, provided they agree to utilize the devices provided by the study team during the study period\n* All patients must sign study-specific informed consent prior to study entry\n\nExclusion Criteria:\n\n* Ongoing treatment for another cancer that is expected to affect the toxicity profile of thoracic radiotherapy\n* Pregnancy or women of childbearing potential and men who are sexually active and not willing\u002Fable to use medically acceptable forms of contraception; this exclusion is necessary because the treatment involved in this study may be significantly teratogenic","ALL","18 Years",{"count":20,"type":21},40,"ESTIMATED","OBSERVATIONAL","This is an observational study involving the collection of patient-generated health data using an Apple Watch, a home pulse oximeter, and a smartphone during a course of proton beam radiotherapy for lung cancer. The study period over which this information is collected will range from the day of study enrollment until two weeks after radiotherapy completion. Subjects will complete a short satisfaction survey at the end of the study period. Other information that is collected as part of routine care for this patient population will be extracted from subjects' medical records during the study period and afterwards.",[25],"Thoracic Cancer","RECRUITING","2026-04-06",{"date":29,"type":30},"2026-04-13","ACTUAL",{"date":32,"type":30},"2024-03-22",{"date":34,"type":21},"2031-03-21",{"name":36,"class":37},"The New York Proton Center","OTHER",1,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":48,"phases":49,"briefSummary":51,"conditions":52,"keywords":59,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":64,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":38},"100463322","prospective-evaluation-of-pencil-beam-scanning-proton-therapy-for-previously-irradiated-tumors-100463322","NCT05313191","Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors","ReRT","Inclusion Criteria:\n\n* Age 18 years\n* Patient provides study specific informed consent prior to study entry.\n* Documented history and physical exam within 90 days prior to registration.\n* ECOG PS 0, 1, or 2 within 90 days prior to registration\n\nExclusion Criteria:\n\n* Non malignant systemic disease that would preclude the patient from receiving study treatment or would prevent required follow up.\n* Prior invasive non study malignancy unless disease free for ≥ 3 years\n\n  * Non melanoma skin cancer, low risk prostate cancer, well differentiated thyroid cancers, in situ carcinomas of the oral cavity, cervix, and other organs, and tumors that are not thought to impact the life expectancy of the patient are permissible.\n* History of active connective tissue disorder (i.e., systemic lupus erythematosus, scleroderma), dermatomyositis, xeroderma pigmentosum",{"count":47,"type":21},1800,"INTERVENTIONAL",[50],"NA","The goal of this clinical research trial is to study the use of differing investigational doses and scheduling for Proton Therapy for tumors previously treated with radiation therapy. Generally, when patients are first treated for cancer with radiation therapy, they are treated with traditional photon (or x-ray) radiation therapy, which uses high-energy waves to kill tumor cells. In some cases, the cancer either returns or a new tumor can present in a different part of the body. With the usual radiation treatment, the photon beams travel all the way through the body. As a result, healthy tissues in front of and behind the tumor are exposed to radiation. Physicians who treat these cases where the tumor has returned often use a much lower dose of radiation to prevent patients from experiencing serious and long-term side-effects. This dose is often not strong enough to destroy the cancerous tumor. Alternatively, they may also treat a smaller area than would be indicated for complete tumor eradication, again in an attempt to prevent serious and long-term toxicities, but at the cost of optimally treating the cancer. Proton therapy, however, may offer a chance to safely deliver a more effective dose and volume of radiation as it is more targeted and can spare healthy tissues surrounding the tumor.\n\nThe reason we are conducting this research study is to look at whether Proton therapy can be a better way to treat reoccurring tumors in patients who have previously received radiation therapy to the same area, compared to treatment approaches used to date.",[53,54,55,56,57,25,58],"CNS Cancer","Head and Neck Cancer","GI Cancer","Gynecologic Cancer","Prostate Cancer","Breast Cancer",[60,61,62,63],"Reirradiation","Cancer","Proton Therapy","Radiation Therapy",{"date":29,"type":30},{"date":66,"type":30},"2022-01-24",{"date":68,"type":21},"2028-01",{"name":36,"class":37},""]