[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":91},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,71],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100631005","low-excision-and-high-suspension-hemorrhoidectomy-versus-conventional-milligan-morgan-hemorrhoidectomy-for-grade-iii-iv-mixed-hemorrhoids-100631005",false,"NCT07495046","Low Excision and High Suspension Hemorrhoidectomy Versus Conventional Milligan-Morgan Hemorrhoidectomy for Grade III-IV Mixed Hemorrhoids","Low Excision and High Suspension Hemorrhoidectomy Versus Conventional Milligan-Morgan Hemorrhoidectomy for Patients With Goligher Grade III-IV Mixed Hemorrhoids","LEHS","Inclusion Criteria:• Age 18-70 years, male or female;\n\n* Diagnosed with Goligher grade III-IV mixed hemorrhoids via anorectal examination;\n* Failed conservative treatment for at least 3 months;\n* Voluntarily participated in the study and agreed to complete the 12-month follow-up.\n\nExclusion Criteria:• Combined with acute perianal abscess, anal fistula, anal fissure, inflammatory bowel disease, rectal prolapse, or anorectal malignancy;\n\n* History of previous anorectal surgery;\n* Severe coagulation dysfunction, cardiopulmonary insufficiency, hepatic\u002Frenal failure, or mental disorders;\n* Pregnancy or lactation;\n* Inability to cooperate with postoperative follow-up and evaluation.","ALL","18 Years","70 Years",{"count":21,"type":22},120,"ESTIMATED","INTERVENTIONAL",[25],"NA","Low Excision and High Suspension Hemorrhoidectomy versus Conventional Milligan-Morgan Hemorrhoidectomy for Mixed Hemorrhoids",[28],"Mixed Hemorrhoids",[28,30,31],"low excision and high suspension hemorrhoidectomy","Milligan-Morgan hemorrhoidectomy;","NOT_YET_RECRUITING","2026-03-21",{"date":35,"type":36},"2026-03-27","ACTUAL",{"date":38,"type":22},"2026-04-01",{"date":40,"type":22},"2026-07-01",{"name":42,"class":43},"The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":23,"phases":56,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100568412","phase-2-the-effect-of-non-invasive-auricular-acupoint-stimulation-on-slow-transmission-constipation-100568412","NCT06680882","The Effect of Non-invasive Auricular Acupoint Stimulation on Slow Transmission Constipation","The Second Hospital Affiliated Anhui University of Chinese Medicine","AAS","Inclusion Criteria: ① Conformity to the diagnostic benchmarks for STC as delineated in the Rome IV criteria; ② Absence of ingestion of any medication influencing gastrointestinal motility within the preceding three months; ③ Provision of informed consent after a comprehensive understanding of the study's objectives; ④ An age range of 40 to 75 years.\n\n\\-\n\nExclusion Criteria: ① Withdrawal from the therapeutic regimen; ② Auricle or ear canal pathologies; ③ Organic defecation disorder; ④ Pregnant or lactating.\n\n\\-","40 Years","75 Years",{"count":55,"type":22},60,[57],"PHASE2","Objective To examine the therapeutic effect and safety of non-invasive auricular acupoint stimulation application on patients with slow transmission constipation.\n\nMethods In a randomized clinical trial, 60 patients diagnosed with slow transit constipation (STC), ranging in age from 40 to 75 years, were allocated into two distinct cohorts: a study group and a control group. The study group, comprising 30 individuals, received a combination therapy of non-invasive auricular acupoint stimulation and prucapride, while the control group, also consisting of 30 patients, was administered prucapride as a monotherapy. To assess the efficacy of the interventions, various parameters were monitored, including serum levels of Neuropeptide Y (NPY), nitric oxide (NO), fecal water content, and gastrointestinal (GI) transit. The comparative therapeutic outcomes were determined by calculating symptom scores.",[60],"Slow Transmission Constipation",[62],"slow transmission constipation","2024-11-06",{"date":65,"type":36},"2024-11-08",{"date":67,"type":22},"2024-11-07",{"date":69,"type":22},"2025-11-01",{"name":42,"class":43},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":23,"phases":79,"briefSummary":81,"conditions":82,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":87,"completionDateStruct":88,"leadSponsor":90,"locationsCount":4},"100567418","phase-1-clinical-trial-of-zuoqing-san-in-treating-ulcerative-colitis-100567418","NCT06667934","Clinical Trial of Zuoqing SAN in Treating Ulcerative Colitis","Inclusion Criteria:① Clinically diagnosed UC; ② The severity of UC is mild to moderate.\n\n\\-\n\nExclusion Criteria:① The severity of UC is severe; ②patient with Severe liver, kidney, heart and brain diseases; ③ Patients with Chinese medicine allergy; ④ Pregnant or lactation patients.\n\n\\-","65 Years",{"count":55,"type":22},[80,57],"PHASE1","The exact efficacy of Zuoqing SAN enema in the treatment of Ulcerative colitis (UC) has been clinically verified. In this study, Zuoqing SAN was used to treat UC patients with large intestine damp-heat syndrome, and the traditional chinese medicine (TCM) syndrome type was large intestine damp-heat syndrome. The changes of symptoms and signs of patients before and after treatment were observed and compared, and the clinical efficacy of Zuoqing SAN in the treatment of UC large intestine damp-heat syndrome was evaluated by combining the changes of patients' symptoms, related blood indicators, improved Mayo total score, overall syndrome efficacy, clinical comprehensive efficacy and other aspects. By replicating the rat UC model, the effects of Zuoqing SAN on general survival state, colonic gross appearance and histopathological changes, related inflammatory factors, peroxisome proliferator-activated receptor γ (PPAR-γ) \u002Fnuclear factor kappa-B（NF-κB) \u002Fsignal transducerand activator of transcription 1 (STAT1) pathway, macrophage M1, M2 phenotype and microangiogenesis were observed in UC rats. Thus, the specific mechanism of Zuoqing SAN in the treatment of UC was revealed. In this study, the therapeutic effect of Zuoqing Powder on UC was investigated through clinical and animal experiments, and the specific mechanism of action was studied.",[83],"Ulcerative Colitis (UC)","2024-10-30",{"date":86,"type":36},"2024-10-31",{"date":84,"type":22},{"date":89,"type":22},"2025-05-01",{"name":42,"class":43},""]