[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"The Third Affiliated Hospital of Kunming Medical College.\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":4},"100568763","constructing-a-predictive-model-for-differentiating-between-benign-and-malignant-solid-pulmonary-nodules-based-on-clinical-and-imaging-features-100568763",false,"NCT06685458","Constructing a Predictive Model for Differentiating Between Benign and Malignant Solid Pulmonary Nodules Based on Clinical and Imaging Features.","Combined With Clinical and Imaging Features, the Prediction Model of Benign and Malignant Solid Pulmonary Nodules Was Constructed","Inclusion Criteria:\n\n* (1) All subjects provided CT imaging obtained from the Third Affiliated Hospital of Kunming Medical University within 2-week period prior to surgery; (2) Complete clinicopathological data of solid nodules were obtained; (3) Surgical intervention for one or more SPN; (4) No prior anti-tumor treatments like radiotherapy or chemotherapy; (5) Age 18 years or older.\n\nExclusion Criteria:\n\n* (1) Patients with incomplete imaging data or medical records; (2) Lung infections that could affect image analysis; (3) Significant respiratory movement artifacts in images impairing imaging analysis; (4) Inconsistent locations of SPN in postoperative pathology reports and preoperative CT images.","ALL","18 Years",{"count":19,"type":20},320,"ESTIMATED","OBSERVATIONAL","Study Objective:\n\nTo comprehensively analyze the preoperative clinical and imaging characteristics of solid pulmonary nodules, investigate the risk factors associated with malignant solid pulmonary nodules, and provide a reference for preoperative treatment decisions.\n\nSignificance of the Study:\n\nAccording to the 2020 Global Cancer Report, lung cancer remains the leading cause of cancer-related deaths worldwide. While the majority of patients with stage I lung cancer achieve long-term survival, survival rates for advanced-stage patients are extremely low. Early screening, diagnosis, and treatment of lung cancer are crucial.\n\nWith the widespread implementation of early lung cancer screening, a growing number of pulmonary nodules are being detected, among which solid pulmonary nodules constitute a significant proportion. Unlike ground-glass nodules, accurately distinguishing between benign and malignant solid nodules is critical for determining appropriate treatment strategies. For benign solid nodules, follow-up observation is the preferred approach, whereas early surgical intervention is essential for malignant solid nodules.\n\nAlthough previous studies have explored the correlation between clinical and imaging characteristics, they have not conducted systematic analyses, and most have been based on small sample sizes. Therefore, this study aims to conduct a comprehensive analysis of preoperative clinical and imaging characteristics, build a predictive model to differentiate between benign and malignant solid pulmonary nodules, and provide a reliable reference for selecting treatment strategies.",[24,25,26],"Lung Cancer","Solid Pulmonary Nodules","Pulmonary Nodules",[28,29,30],"Lung Cancer Screening","Nodule Malignancy Prediction","Preoperative Imaging Analysis","NOT_YET_RECRUITING","2024-11-10",{"date":34,"type":35},"2024-11-12","ACTUAL",{"date":37,"type":20},"2024-11-15",{"date":39,"type":20},"2025-02-20",{"name":41,"class":42},"The Third Affiliated Hospital of Kunming Medical College.","OTHER",{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":52,"conditions":53,"keywords":58,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100565712","retrospective-analysis-of-clinical-and-ct-features-to-predict-spread-through-air-space-in-stage-ia-lung-adenocarcinoma-100565712","NCT06645743","Retrospective Analysis of Clinical and CT Features to Predict Spread Through Air Space in Stage IA Lung Adenocarcinoma","Clinical and Imaging Features Were Used to Predict the Occurrence of Spread Through Air Space in Stage IA Lung Adenocarcinoma","Inclusion Criteria:\n\nPreoperative CT images reported that the maximum diameter of pulmonary nodules was less than 3 cm\n\nAll subjects provided CT imaging obtained from Yunnan Cancer Hospital within a 2-week period prior to surgery\n\nPostoperative pathological diagnosis of invasive lung adenocarcinoma\n\nRemote metastasis was excluded by preoperative imaging (CT, PET-CT, ultrasound, etc.)\n\nAge ≥ 18 years\n\nExclusion Criteria:\n\nIncomplete collection of medical records, imaging data, or hematology data\n\nPreoperative complications of other malignant tumors\n\nUnclear correspondence between postoperative pathological report and preoperative CT nodule location\n\nImages do not meet analysis conditions due to pulmonary infection or large respiratory motion artifacts\n\nPostoperative pathology revealed two or more nodules classified as infiltrating adenocarcinoma\n\nPrior lung surgery or preoperative neoadjuvant therapy",{"count":51,"type":20},1100,"The purpose of this study is to provide a basis for the selection of surgical methods for patients with stage IA lung adenocarcinoma. Air cavity dissemination is a poor prognostic factor for patients with stage IA lung adenocarcinoma. We retrospectively collected clinical and imaging data of stage IA lung adenocarcinoma patients. Independent risk factors associated with spread through air space in stage IA lung adenocarcinoma patients were analyzed, so as to predict the occurrence of spread through air space and provide basis for the selection of surgical methods",[54,55,56,57],"Tomography, X-Ray Computed","Spread Through Air Space","Clinical Features","Stage IA Adenocarcinoma of Lung",[59,60,61,62],"clinical feature","Radiologic characteristic","Lung adenocarcinoma","spread through air space","2024-10-15",{"date":65,"type":35},"2024-10-17",{"date":67,"type":20},"2024-10-25",{"date":69,"type":20},"2025-02-21",{"name":41,"class":42},1,""]