[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"The Third People's Hospital of Huizhou\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":70},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100641065","efficacy-and-mechanism-of-yanjiu-needle-for-pharyngeal-dysphagia-based-on-semg-features-100641065",false,"NCT07656025","Efficacy and Mechanism of 'Yanjiu Needle' for Pharyngeal Dysphagia Based on sEMG Features","Therapeutic Efficacy and Mechanistic Study of Yanjiu Acupuncture in Patients With Pharyngeal Dysphagia Based on Surface Electromyographic Features","Inclusion Criteria:\n\n* First onset of stroke with swallowing disorders lasting for 2 weeks to 6 months;\n* Stable vital signs, able to understand and execute physician instructions, and cooperate with treatment;\n* Age range: 40-75 years old, male or female not limited;\n* Functional Oral Intake Scale (FOIS) classification ≤ 4;\n* The patient's surgical site can receive acupuncture treatment;\n* Informed consent from patients or family members.\n\nExclusion Criteria:\n\n* Individuals with unstable vital signs who are unable to complete assessment and treatment;\n* Individuals with severe cognitive impairment, communication barriers, or other mental illnesses who are unable to cooperate with treatment;\n* Individuals with a history of oral, pharyngeal, and esophageal structural abnormalities, cricopharyngeal muscle stenosis, and cancer;\n* Confirmed by cranial CT\u002FMRI as a deceased with brainstem infarction\u002Fhemorrhage and extensive cerebral infarction;\n* Participants in other clinical trials;\n* Those who cannot accept surface electromyography examination; Pregnant and lactating women.","ALL","40 Years","75 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Dysphagia is one of the most common and serious complications following stroke. It can easily lead to aspiration and aspiration pneumonia, reduce patients' quality of life, increase healthcare costs, and result in high mortality rates, making it a clinical issue that urgently needs to be addressed. Current mainstream therapies have limitations: neurostimulation targets a single pathway, while rehabilitation training offers only limited improvement in microcirculation and suffers from low patient compliance. Although acupuncture shows promise, it lacks high-quality randomized controlled evidence, and the specific acupuncture techniques lack standardized operational protocols, limiting their widespread adoption. In preliminary clinical practice, Chen Xiaokai, a renowned traditional Chinese medicine practitioner in Guangdong Province, developed the \"Nine Pharyngeal Acupoints\" (including Lianquan and Renying) based on the \"resolving knots\" theory. This approach can rapidly improve pharyngeal muscle tone and swallowing function. Basic research has confirmed that stimulation of these acupoints promotes pharyngeal circulation, activates the brainstem, and aids in the restoration of the swallowing reflex. This study aims to conduct a single-center, assessor-blinded, randomized, controlled, prospective superiority clinical trial. Using surface electromyography (EMG) as the core assessment tool, combined with swallowing videofluoroscopy and functional scales, the study will analyze the efficacy and neuro-muscular regulatory mechanisms of the \"Nine Pharyngeal Acupoints\" technique. The study is expected to clarify its therapeutic efficacy, establish standard operating procedures, and provide a basis for clinical implementation.",[27,28,29],"Acupuncture","Dysphagia","Surface EMG",[31,28,32,27,33,34],"Stroke","Nine needles for swallowing","Clinical research","mechanism","NOT_YET_RECRUITING","2026-06-16",{"date":38,"type":39},"2026-06-18","ACTUAL",{"date":41,"type":21},"2026-06-20",{"date":43,"type":21},"2028-12-20",{"name":45,"class":46},"The Third People's Hospital of Huizhou","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":4},"100635314","electroacupuncture-at-jing-well-points-for-chronic-disorders-of-consciousness-a-randomized-controlled-study-with-multimodal-assessment-100635314","NCT07551076","Electroacupuncture at Jing-Well Points for Chronic Disorders of Consciousness: A Randomized Controlled Study With Multimodal Assessment","Randomized Controlled Study of Electroacupuncture Stimulation at Jing-Well Points for Chronic Disorders of Consciousness Based on Multimodal Assessment","Inclusion Criteria:\n\n* Meet the above diagnostic criteria for pDoC and be diagnosed as Vegetative State (VS) \u002F Unresponsive Wakefulness Syndrome (UWS) or Minimally Conscious State (MCS) based on at least two assessments using the Coma Recovery Scale-Revised (CRS-R);\n* First onset of impaired consciousness with a clear etiology (traumatic brain injury \u002F intracerebral hemorrhage \u002F cerebral infarction) and a complete medical history;\n* No obvious hydrocephalus or severe cerebral atrophy, with a disease course ranging from 28 days to 6 months;\n* Aged between 18 and 72 years, with no gender restriction;\n* No significant cognitive, hearing, or visual impairment prior to onset;\n* Able to communicate accurately in Chinese before onset, with no history of major neurological or psychiatric disorders;\n* Clinically stable and not having participated in other clinical trials within the past 3 months;\n* Informed consent signed by the patient's family member or legal representative.\n\nExclusion Criteria:\n\n* Patients with consciousness disturbance of unknown etiology;\n* Patients in coma due to neurodegenerative diseases, intracranial infection, or after brain tumor surgery;\n* Patients with severe complications;\n* Heart rate exceeding 70% of the age-predicted maximum heart rate, a decrease of \\>20% from resting heart rate, \\\u003C40 beats\u002Fmin, or \\>130 beats\u002Fmin;\n* Blood oxygen saturation \\\u003C88%; systolic blood pressure \\>180 mmHg, or presence of orthostatic hypotension, mean arterial pressure \\\u003C65 mmHg or \\>110 mmHg;\n* Patients with metallic implants such as cardiac pacemakers or spinal cord stimulators;\n* History of substance abuse prior to onset;\n* Patients with hyperalgesia in the stimulation area who are not suitable for electrostimulation at Jing-Well points;\n* Any other factors that may affect assessment and treatment;\n* Patients with uncontrolled epileptic seizures or status epilepticus;\n* Patients in whom ERP cannot be measured at the corresponding sites due to skull defects or other reasons;\n* Pregnant female patients.","18 Years","72 Years",{"count":57,"type":21},66,[24],"Disorder of consciousness (DOC) is a common complication of severe central nervous system injury. It is defined as prolonged DOC when lasting more than 28 days. About 300,000-800,000 patients are affected worldwide, with an annual mortality rate of 29%-50%, causing a heavy social and family burden.\n\nAlthough progress has been made in pathophysiology, clinical outcomes remain unsatisfactory, and arousal treatment for DOC is still challenging. Internationally recommended therapies, such as neurotrophic drugs, hyperbaric oxygen and invasive neuromodulation, have side effects or uncertain efficacy.\n\nIn traditional Chinese medicine, post-TBI DOC is classified as \"shen hun\" (mental clouding). Bloodletting at Jing-Well points promotes arousal by regulating qi and blood and unblocking collaterals. Preliminary studies showed it may improve consciousness in DOC patients, but with small samples and short observation periods.\n\nAcupuncture, such as the Xingnao Kaiqiao method, induces arousal by improving cerebral blood flow and activating neural networks. Our team proposed the \"Jing-Well point-brain correlation\" hypothesis and found that electrostimulation at Jing-Well points improves cognitive function, but lacks standardized assessment and large-sample evidence.\n\nFurther research is needed to confirm its efficacy, mechanisms and suitable populations to provide high-quality evidence-based support.",[61],"Disorder of Consciousness","2026-04-24",{"date":64,"type":39},"2026-04-30",{"date":66,"type":21},"2026-05-30",{"date":68,"type":21},"2027-03-01",{"name":45,"class":46},""]