[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Thomas Pilgrim\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":49},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100571439","school-based-program-for-the-prevention-of-rheumatic-heart-disease-in-endemic-regions-100571439",false,"NCT06720272","School-based Program for the Prevention of Rheumatic Heart Disease in Endemic Regions","Effectiveness of an Integrated Program for the Prevention of Rheumatic Heart Disease in Endemic Regions: a Stepped Wedge Cluster Randomized Trial","PREVENT","Inclusion Criteria:\n\n\\- Children aged 5-16 years\n\nExclusion Criteria:\n\n* Children \u002F primary caregivers not providing informed consent to participate\n* Children not attending one of the selected schools",true,"ALL","5 Years","16 Years",{"count":22,"type":23},6000,"ESTIMATED","INTERVENTIONAL",[26],"NA","The overall objective of the PREVENT trial is to evaluate the effectiveness of an integrated, school-based program for the prevention of rheumatic heart disease (RHD) in regions with an endemic pattern of RHD.\n\nWe conduct a stepped wedge cluster randomized trial in randomly selected schools in Nepal and Zambia.\n\nThe intervention will be delivered at the level of the school and consists in the introduction of a dedicated school-nurse program providing health care through education about RHD, assessment, intervention, and follow-up of GABHS pharyngitis, and facilitation of secondary antibiotic prophylaxis for children with RHD.",[29],"Rheumatic Heart Disease in Children",[31,32,33,34,35],"rheumatic heart disease","valvular heart disease","prevention","streptococcal pharyngitis","rheumatic fever","RECRUITING","2026-01-16",{"date":39,"type":40},"2026-01-20","ACTUAL",{"date":42,"type":40},"2024-12-15",{"date":44,"type":23},"2028-02",{"name":46,"class":47},"Thomas Pilgrim","OTHER",2,""]