[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Thomayer University Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":20,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100452958","czech-aatd-registry-100452958",false,"NCT05178277","Czech AATD Registry","Czech Alpha-1 Antitrypsin Deficiency Registry, the National Observational Study.","Inclusion Criteria:\n\n* Patients with alpha-1-antitrypsin deficiency\n\nExclusion Criteria:\n\n* Patient disagreement with inclusion in the study","ALL",{"count":18,"type":19},300,"ESTIMATED","20 Years","OBSERVATIONAL","Alpha-1-antitrypsin deficiency is the most common congenital disease of the respiratory system, leading to early pulmonary emphysema or bronchiectasis. Pulmonary involvement significantly accelerates active cigarette smoking. Patients with alpha-1-antitrypsin deficiency may also have liver cirrhosis, vasculitis, skin or intestinal disorders.\n\nThe AATD Registry is a non-interventional multicenter retrospective prospective longitudinal follow-up of patients with alpha-1-antitrypsin deficiency.\n\nThe aim of the AATD National Registry is to collect and analyze clinical data in patients with alpha-1 antitrypsin deficiency.",[24],"Alpha-1-antitrypsin Deficiency",[26,27,28],"Alpha-1-antitrypsin deficiency","AATD","national registry","RECRUITING","2021-12-16",{"date":32,"type":33},"2022-01-05","ACTUAL",{"date":35,"type":33},"2018-01-01",{"date":37,"type":19},"2035-12-31",{"name":39,"class":40},"Thomayer University Hospital","OTHER",""]