[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Toronto Rehabilitation Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":126},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,69,96],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100566654","optimal-intensity-of-reactive-balance-training-for-healthy-older-adults-100566654",false,"NCT06657989","Optimal Intensity of Reactive Balance Training for Healthy Older Adults","Inclusion Criteria:\n\n* Community-dwelling older adults (65-80 years old)\n\nExclusion Criteria:\n\n* Unable to stand independently without upper-limb support for \\>30 seconds and\u002For walk independently (without a gait aid) for ≥10 metres;\n* Diagnosed neurological condition that could affect balance control (e.g., stroke, Parkinson's disease);\n* Score below normative values on the Montreal Cognitive Assessment;\n* Score below age-matched normative values for sensory and motor function, as assessed using the FallScreen battery;\n* Have insufficient English language comprehension such that they cannot understand instructions;\n* Have contraindications to reactive balance training such as severe osteoporosis; and\u002For\n* Are currently attending physiotherapy or supervised exercise.",true,"ALL","65 Years","80 Years",{"count":20,"type":21},96,"ESTIMATED","INTERVENTIONAL",[24],"NA","Falls in daily life are a serious risk for older adults. A new type of balance training, called reactive balance training (RBT) involves people losing balance many times so that they can practice fast balance reactions, like stepping reactions. Differences in training program features might explain differences in the results of previous RBT studies. Training intensity is the difficulty or challenge of the training program. It would be valuable to know if high-intensity RBT improves balance reactions quickly. The main goal of this study is to see if more intense RBT improves balance reactions faster than less intense RBT. The investigators will compare how quickly people improve balance reactions between high- and moderate-intensity RBT, and between RBT and a control program that does not include RBT. The investigators will also test if the improvements in balance reactions last after the training program is over. The secondary goals are to understand exactly how balance reactions improve with training, and to determine if people who complete RBT improve their general balance skills, and falls efficacy more than people who do not complete RBT.",[27],"Accidental Falls",[29,30,31,32],"Postural balance","Aging","Biomechanics","Rehabilitation","RECRUITING","2025-01-22",{"date":36,"type":37},"2025-01-27","ACTUAL",{"date":39,"type":37},"2025-01-21",{"date":41,"type":21},"2027-12-31",{"name":43,"class":44},"Toronto Rehabilitation Institute","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":16,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":63,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":45},"100558737","optimal-intensity-of-reactive-balance-training-post-stroke-100558737","NCT06555016","Optimal Intensity of Reactive Balance Training Post-stroke","Optimal Intensity of Reactive Balance Training Post-stroke: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Chronic stroke (\\>6 months post-stroke)\n\nExclusion Criteria:\n\n* Are unable to stand independently without upper-limb support for \\>30 seconds and\u002For walk independently (without a gait aid) for ≥10 metres;\n* Have another neurological condition that could affect balance control (e.g., Parkinson's disease);\n* Have cognitive impairment (Montreal Cognitive Assessment8 score \\\u003C26), or severe language or communication difficulties affecting understanding instructions;\n* Have contraindications to RBT (has described by Mansfield et al., 2021), such as osteoporosis, activity restrictions due to cardiac event\u002Fsurgery, or severe spasticity in the lower extremity; and\u002For\n* Are currently attending in- or out-patient physiotherapy or supervised exercise.","20 Years",{"count":55,"type":21},63,[24],"Falls in daily life are a serious risk for people with stroke. A new type of balance training, called reactive balance training (RBT). may help to reduce this risk of falling. In some previous studies participants improved their balance reactions a lot after RBT, whereas others did not improve at all. These studies used different types and amounts of training. Differences in training program features might explain differences in the study results.\n\nTraining intensity is the difficulty or challenge of the training program. For other types of exercise (like 'cardio' or strength training) if the intensity of exercise is increased, someone can get the same benefits in less time than with lower intensity exercise. Physiotherapists report that they have limited time in rehabilitation to do everything they need to do with their stroke patients, so it would be valuable to know if high-intensity RBT improves balance reactions quickly. The goal of this study is to see if more intense RBT improves balance reactions faster than less intense RBT.\n\nPeople with chronic stroke will be randomly placed in one of three groups: high-intensity RBT, moderate-intensity RBT, or a walking control group. The investigators will find the fastest moving platform speed that participants can respond to with single step (multi-step threshold). There will then be 4 1-hour long training sessions in one week. Participants in the high-intensity group will experience platform movements that are 50% faster than the multi-step threshold. Participants in the moderate-intensity group will experience platform movements at the multi-step threshold. Participants in both RBT groups will experience 36 multi-directional platform movements in each training session, causing them to start to fall forwards, to the left, or to the right. Participants in the walking group will walk on the platform 36 times without any platform movements. The investigators will measure how quickly people improve their balance reactions over the training program.",[59,60],"Accidental Fall","Stroke",[29,32,62],"Exercise",{"date":36,"type":37},{"date":65,"type":37},"2024-11-11",{"date":67,"type":21},"2027-06",{"name":43,"class":44},{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":11,"sex":16,"minAge":76,"maxAge":4,"enrollmentInfo":77,"targetDuration":4,"studyType":22,"phases":79,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":45},"100459892","self-management-interventions-for-long-covid-19-100459892","NCT05268523","Self-Management Interventions for Long COVID-19","Interventions to Teach Self-management Skills for Persisting Symptoms of COVID-19: Minimizing Impact of Symptoms on Everyday Functioning and on Healthcare Usage\u002Futilization","Inclusion Criteria:\n\n* Clinically diagnosed Long-COVID plus PCR positivity with and without hospitalization\n* 3-12 months post-diagnosis of COVID-19\n* \\>2 self-reported persisting symptoms in \\>1 mood, cognitive and\u002For somatic symptom domain\n* Age \\>18\n* English speaking\n* Private access to computer\u002Finternet\n\nExclusion Criteria:\n\n* Acute ventilator support\n* Diagnosed dementia\n* Past\u002Fpresent history of psychotic illness or mania and, because of potential overlap in symptoms, diagnosis of chronic fatigue syndrome, fibromyalgia, chronic lyme disease or traumatic brain injury\n* Long-COVID symptom severity (i.e., physical, cognitive, emotional symptoms) at a level that would significantly interfere with attendance\u002Fadherence to the intervention protocol","18 Years",{"count":78,"type":21},270,[24],"The purpose of this study is to investigate and compare the feasibility and efficacy of two group-based interventions (education vs. mindfulness) to help self-manage Long-COVID symptoms.",[82],"COVID-19",[84,85,86,87],"Long-term effects","Self-management","Group therapy","Telerehabilitation","2024-11-21",{"date":90,"type":37},"2024-11-25",{"date":92,"type":37},"2021-11-23",{"date":94,"type":21},"2025-12-01",{"name":43,"class":44},{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":16,"minAge":76,"maxAge":103,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":113,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":120,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":45},"100387949","online-memory-intervention-for-individuals-with-traumatic-brain-injury-100387949","NCT04331392","Online Memory Intervention for Individuals with Traumatic Brain Injury","Remotely Delivered Environmental Enrichment Intervention for Traumatic Brain Injury: a Randomized Controlled Trial","Inclusion Criteria:\n\n* acute care diagnosis of m-sTBI\n* PTA of 24 hours or more and\u002For lowest GCS \\\u003C13\n* positive CT or MRI; (4) between 18 to 55 years of age\n* fluency in English; (6) competency to provide informed consent or availability of a legal decision maker\n* basic computer skills (use of internet\u002Femail, mouse and arrow keys)\n* functional use of at least one upper extremity for computer use\n* resident of Greater Toronto Area (to facilitate access to the MRI).\n\nExclusion Criteria:\n\n* neurological disorder other than TBI (e.g., dementia, stroke)\n* diagnosis of a neurodevelopmental disorder\n* TBI sustained before age 18\n* systemic comorbidities (e.g., lupus, diabetes)\n* current diagnosis of aphasia\n* presence of metal inside the body (e.g., surgical clips, pacemaker) leading to ineligibility for an MRI.","55 Years",{"count":105,"type":21},84,[24],"This study will examine the behavioural and neurophysiological efficacy and feasibility of an online spatial navigation intervention for improving memory and brain health in individuals who have sustained moderate-severe traumatic brain injury.",[109,110,111,112],"Brain Injuries, Traumatic","Brain Injury Traumatic Severe","Brain Injury Traumatic Moderate","Brain Injury, Chronic",[114,115,116,117,118,119],"Environmental enrichment","spatial navigation","traumatic brain injury","neurorehabilitation","telerehabilitation","hippocampus",{"date":90,"type":37},{"date":122,"type":37},"2018-10-30",{"date":124,"type":21},"2027-02",{"name":43,"class":44},""]