[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Touro University, California\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100609026","fructose-intestinal-gluconeogenesis-100609026",false,"NCT07209202","Fructose Intestinal Gluconeogenesis","Fructose Metabolism Effects on the Liver: Unraveling the Role of Defective Intestinal GNG in Individuals With Obesity","FIG","Inclusion Criteria:\n\n* BMI 30 to 38 kg\u002Fm2 (obese group) or BMI 19 to 25 kg\u002Fm2 (lean group)\n\nExclusion Criteria:\n\n* Pregnancy or lactation within the past six months;\n* Type 1 or 2 diabetes mellitus (including fasting glucose ≥126 mg\u002FdL, HgbA1c ≥6.5%);\n* History of liver disease or AST and ALT 2x above the upper limit of normal;\n* Fasting triglyceride \\> 300 mg\u002Fdl; total cholesterol levels above the 95th percentile for age and sex;\n* Hemoglobin (Hgb) \\\u003C12.5g\u002Fd or hematocrit\\\u003C3x Hgb value;\n* Report of HIV or hepatitis B or C infection;\n* History of cancer, other than basal cell or squamous cell carcinoma or kidney disease stage 3 or higher or patients currently on dialysis;\n* Use of any anti-diabetic medications or hypolipidemic agents in the past six months;\n* History of surgical procedure for obesity;\n* Change in body weight \\>5% in the past six months (by self-report);\n* History of other conditions known to affect insulin sensitivity and lipid metabolism (e.g., polycystic ovary syndrome), history of galactosemia, hereditary fructose intolerance, or who test positive for fructose malabsorption at screening;\n* Known intolerance to acetaminophen.",true,"ALL","20 Years","55 Years",{"count":22,"type":23},40,"ESTIMATED","INTERVENTIONAL",[26],"NA","This study will test the hypothesis that within a defined range of fructose intake, the ability to convert fructose to glucose (via gluconeogenesis) in the small intestine plays a protective role for the liver, shielding it from the deleterious effects of fructose. We will investigate whether this protective effect of the intestine is impaired in individuals with obesity.",[29,30],"Healthy Participants","Obese But Otherwise Healthy Participants",[32,33],"Fructose","Sugar","RECRUITING","2026-03-04",{"date":37,"type":38},"2026-03-06","ACTUAL",{"date":40,"type":38},"2026-03-02",{"date":42,"type":23},"2030-06",{"name":44,"class":45},"Touro University, California","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":18,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":24,"phases":57,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":46},"100616469","the-solanoconnex-trial-evaluation-of-a-mental-health-access-project-100616469","NCT07306013","The SolanoConnex Trial: Evaluation of a Mental Health Access Project","The SolanoConnex Trial: A Single-blind Randomized Controlled Trial of a Digital and Community-based Mental Health Access Project","Inclusion Criteria:\n\n* Age 18 or older\n* Resident of Solano County, CA.\n* Mild to moderate mental health symptoms as reported on the DSM-5 Level 1 Measure for Adult Mental Health screening form.\n* Own a personal smartphone with internet access or a data plan to facilitate engagement with the digital platform.\n* Be fluent in English, as all study components will be conducted in English.\n* Have not previously used SolanoConnex.org.\n\nExclusion Criteria:\n\n* Are currently engaged in or have had comprehensive case management or counseling services within the past 6 months.\n* Do not reside in Solano County.\n* Lack fluency in English, as study materials and communications will be conducted in English.\n* Have previously accessed SolanoConnex.org, as prior exposure may influence study outcomes.","18 Years",{"count":56,"type":23},200,[26],"The goal of this study is to evaluate the effectiveness of the SolanoConnex.org program on help-seeking attitudes and help-seeking behaviors among users compared to a control group. This study will employ a randomized controlled trial design with two parallel arms. Participants in the intervention group will receive full access and orientation to SolanoConnex.org, including multiple features designed to enhance engagement with local mental health resources. Participants in the control group will receive publicly available mental health resources. The primary outcome is any use of mental health services including conversations and communication, digital engagement and media consumption, direct service use or self-help and alternative support all of which will be self-reported through digital diaries prompted every two weeks. Secondary outcomes are endorsed and anticipated Stigma related to mental health, help-seeking attitudes, self-efficacy in seeking mental health care. Potential covariates include demographics, past mental health service use and satisfaction, readiness to change, and discrimination experiences during past healthcare use.",[60],"Mental Health",[62,63,64],"mental health","web application","community-based","2025-12-18",{"date":67,"type":38},"2025-12-26",{"date":69,"type":38},"2025-07-13",{"date":71,"type":23},"2026-06-30",{"name":44,"class":45},""]