[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Umm Al-Qura University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":135},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,76,103],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":4},"100617764","virtual-reality-based-vs-traditional-physiotherapy-for-balance-frailty-and-fall-prevention-in-adults-aged-45-years-and-older-100617764",false,"NCT07322861","Virtual Reality-Based vs Traditional Physiotherapy for Balance, Frailty, and Fall Prevention in Adults Aged 45 Years and Older","A Controlled Trial Comparing Virtual Reality-Based PABLO Training With Traditional Otago Physiotherapy for Balance, Frailty, and Fall Risk in Adults Aged 45 Years and Older","Inclusion Criteria:\n\n* Adults aged 40 years and older\n* History of at least one fall in the past 12 months OR clinical evidence of balance dysfunction\n* Ability to walk at least 10 meters, with or without an assistive device\n* Adequate cognitive function, defined as Mini-Mental State Examination (MMSE) score ≥ 24\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Severe cognitive impairment (MMSE \\\u003C 24)\n* Unstable cardiovascular, musculoskeletal, or neurological conditions that contraindicate exercise participation\n* Severe uncorrected visual or auditory impairment that interferes with training or assessments\n* Current participation in another structured exercise or rehabilitation program\n* Any medical condition deemed unsafe for participation by the treating physiotherapist","ALL","40 Years",{"count":19,"type":20},80,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study will compare two exercise-based rehabilitation programs to improve balance and reduce fall risk in adults aged 45 years and older who have had at least one fall in the past year or have balance problems. Participants will be assigned to one of two groups: (1) a virtual reality (VR) exercise program using the PABLO system, or (2) a traditional physiotherapy program based on the Otago approach. Both programs will include balance training, strength\u002Fpower exercises, aerobic activity, and flexibility. The program will last 12 weeks, with two supervised sessions per week (about 30 minutes each). Assessments will be completed at the start of the study and again after 12 weeks. The main outcomes include frailty status, number of falls, mobility (Timed Up and Go test), and balance (Berg Balance Scale). Additional outcomes include grip strength, quality of life (SF-12), and program adherence and safety. The study will help determine whether VR-based rehabilitation improves participation and outcomes compared with traditional physiotherapy.",[26,27,28,29],"Frailty","Falls","Balance Deficits","Mobility Limitations",[31,32,33,26,34],"Virtual Reality Rehabilitation","Balance Training","Fall Prevention","Exergaming","NOT_YET_RECRUITING","2025-12-29",{"date":38,"type":39},"2026-01-07","ACTUAL",{"date":41,"type":20},"2026-01-01",{"date":43,"type":20},"2026-06-01",{"name":45,"class":46},"Umm Al-Qura University","OTHER",{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":21,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100502190","conservative-management-for-adolescent-idiopathic-scoliosis-100502190","NCT05819034","Conservative Management for Adolescent Idiopathic Scoliosis","Orthotic Management for Controlling Scoliotic Curve Progression in Adolescent Idiopathic Scoliosis","The inclusion criteria will be:\n\n* Adolescents of both sexes with an age range between 10-17 years.\n* They were diagnosed with Adolescent idiopathic scoliosis by an orthopedic specialist, confirmed through (loaded) X- rays.\n* They have mild non-structural scoliosis with Cobb's angle measurement of between 10 and 25 degrees\n* They have Single major thoracolumbar curve located between T6-7 to L1-2, apex at T12 or L1.\n* They have good health conditions except for scoliosis.\n* They can understand and communicate with no mental abnormalities.\n\nThe exclusion criteria will be:\n\n* Adolescents with cerebral palsy or other degenerative neurological disorders;\n* Participants with nutritional disorders e.g. diabetes or vascular disorders.\n* Participants with a scoliotic curve with angle \\> 25° will be excluded.\n* Participants will be excluded from this study if they have inflexible spinal deformities interfering with spinal mobility,\n* Participants who were subjected to any corrective surgery to their spine within the previous two years.\n* Participants will be also excluded if their skin were sensitive or inflamed to any materials used.\n* Participants who have seizures, perceptual disorders, visual problems, and auditory deficits\n* Participants who have leg length discrepancy\n* Participants who have scoliosis developed as a consequence of traumatic scoliosis.","10 Years","17 Years",{"count":57,"type":20},60,[23],"Idiopathic scoliosis is a living problem that resists correction. The underlying cause of the such disorder is unknown but directed more toward muscular disorders. However recent clinical observation showed a possible neuromuscular compromise early in those patients. The main purpose of this study is to develop a treatment procedure to correct the degree of bony curvature in patients with Idiopathic scoliosis through developing a neuromuscular corrective approach that might be a more effective conservative treatment protocol for such disorder.",[61],"Scoliosis; Adolescence",[63,64,65],"Adolescents Idiopathic Scoliosis","Physical Therapy","Orthosis","RECRUITING","2025-09-08",{"date":69,"type":39},"2025-09-15",{"date":71,"type":39},"2024-02-01",{"date":73,"type":20},"2025-12-20",{"name":45,"class":46},1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":83,"sex":16,"minAge":17,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":21,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":100,"leadSponsor":102,"locationsCount":75},"100572645","evaluating-the-impact-of-a-meta-quest-3-gamified-vr-rehabilitation-program-in-knee-osteoarthritis-100572645","NCT06735963","Evaluating the Impact of a Meta Quest 3 Gamified VR Rehabilitation Program in Knee Osteoarthritis","Evaluating the Impact of a Meta Quest 3 Gamified VR Rehabilitation Program on Pain, Functionality, Disability, and Balance in Knee Osteoarthritis: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Age: 40-64 years\n* Diagnosis: Knee OA (Stages 2 or 3 based on American College of Rheumatology criteria)\n* Ability to read and understand Arabic\n\nExclusion Criteria:\n\n* Recent lower extremity surgery\u002Ffractures\n* Other rheumatologic or cardiovascular conditions\n* Visual\u002Fauditory impairments\n* Dizziness or vertigo",true,"64 Years",{"count":86,"type":20},90,[23],"The goal of this clinical trial is to learn if a gamified virtual reality (VR) rehabilitation program can effectively reduce pain, improve functionality, and enhance balance in adults aged 40-64 years diagnosed with knee osteoarthritis. The main questions it aims to answer are:\n\nCan the VR rehabilitation program reduce pain and disability compared to conventional physical therapy alone? Can the VR rehabilitation program improve balance and functionality in patients with knee osteoarthritis? Researchers will compare a group receiving the VR-based rehabilitation program alongside conventional therapy to a group receiving only conventional therapy to see if the addition of VR leads to superior outcomes.\n\nParticipants will:\n\nUndergo either VR-based rehabilitation combined with conventional therapy or conventional therapy alone.\n\nComplete assessments at three time points (baseline, 3 weeks, and 7 weeks) using measures such as pain scales, disability indices, and balance tests.",[90],"Knee Osteoarthristis",[92,93,94,95],"osteoarthritis","virtual reality","game","rehabilitation","2024-12-11",{"date":98,"type":39},"2024-12-16",{"date":96,"type":20},{"date":101,"type":20},"2025-07-20",{"name":45,"class":46},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":11,"sex":16,"minAge":110,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":117,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":75},"100548141","comparative-effectiveness-of-different-drugs-used-to-trat-patients-in-rheumatoid-arthritis-saudi-database-rasd-100548141","NCT06417138","Comparative Effectiveness of Different Drugs Used to tr€at Patients in Rheumatoid Arthritis Saudi Database (RASD)\"","Comparative Effectiveness of Different Drugs Used to Treat Patients in Rheumatoid Arthritis Saudi Database (RASD) The Primary Objective of This Study is to Compare the Effectiveness of Different Biological Disease Modifying Antirheumatic Drugs (bDMARDs) and Targeted Synthetic (tsDMARDs) Using DAS-28-CRP and CDAI Scores.","Inclusion Criteria:\n\n* All those patients who are age of 18 years and above and\n* meeting 2010 American College of Rheumatology classification criteria for rheumatoid arthritis.\n* Both male and female gender will be included.\n* There should be minimum of 12 months follow up with at least 3 documented visits of these patients to health care facilities.\n\nExclusion Criteria:\n\n* Any patient who did not meet the inclusion criteria will be excluded from the study.\n* Any patient who cannot recall the exact date of starting his drugs will be excluded during data analysis.","18 Years",{"count":112,"type":20},800,"OBSERVATIONAL","Comparative effectiveness of different drugs used to treat patients in Rheumatoid Arthritis Saudi database (RASD)\n\nThe goal of this observational study is to compare the effectiveness of different biological Disease Modifying Antirheumatic Drugs (bDMARDs) and targeted synthetic (tsDMARDs) using Disease Activity Score - 28 joints - C-Reactive Protien (DAS-28-CRP) and Clinical Disease Activity Index (CDAI) scores. In rheumatoid arthritis patients in Saudi Arabia who are part of Rheumatoid Arthritis Saudi Database (RASD).\n\nThe main question\\[s\\] it aims to answer:\n\n* What is the most effective drug (biologocal or targeted synthetic) disease modifying antirheumatic drug used to treat rheumatoid arthritis in Saudi Arabia?\n* We are going to use two outcome mesures: Disease Activity Score - 28 joints - C-Reactive Protien (DAS-28-CRP) and Clinical Disease Activity Index (CDAI) scores\n\nResearchers will compare the treatment of rheumatoid arthritis using specific outcome measures in Rheumatoid Arthritis in Saudi Arabia.\n\n* Participants will be enrolled after a signed written concent in our Rheumatoid Arthritis Saudi Databas (RASD).\n* Their treatment data will used to compare the effectiveness of different drugs they are using.",[116],"Rheumatoid Arthritis RA",[118,119,120,121,122,123,124,125,126],"Rheumatoid Arthritis","Remission","Biological DMARDs","Targeted synthetic DMARDs","DAS-28-CRP","CDAI","Low disease activity","Comparative effectiveness","Efficacy","2024-06-06",{"date":129,"type":39},"2024-06-11",{"date":131,"type":39},"2023-12-15",{"date":133,"type":20},"2025-03-15",{"name":45,"class":46},""]