[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Unilever R&D\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":91},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,43,67],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100624907","evaluation-of-a-toothpaste-containing-a-gum-health-active-in-participants-with-gingival-problem-100624907",false,"NCT07415733","Evaluation of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem","A Randomized Clinical Study on the Effect of a Toothpaste Containing a Gum Health Active in Participants With Gingival Problem","Inclusion Criteria:\n\n* Participants need to be competent i.e., able to understand what is to take place and able to provide a free decision on agreeing to the activity\u002Ftaking part in the study on this.\n* Participants must be able to read and understand study instructions and any other relevant study documents.\n* Have at least 20 natural teeth without subgingival calculus, including 5 assessable teeth (excluding 3rd molars) in each quadrant.\n* Have a mean whole mouth BOP ≥ 10% at screening.\n* Willing to follow the lifestyle and dietary restrictions as detailed in the Information Sheet for study.\n\nExclusion Criteria:\n\n* Be pregnant or breastfeeding.\n* Participants who participated in gum health study within 3 months prior to screening.\n* Current participation in any other cosmetic studies, any dental clinical studies or clinical trials.\n* Participants who have used any gum health products in the 4 weeks prior to screening.\n* Obvious signs of untreated caries or significant periodontal disease, which in the opinion of the study dentist, will affect either the scientific validity of the study or if the participant to take part in the study would affect their wellbeing.\n* Have more than three sites with a probing pocket depth (PPD) of ≥ 5 mm.\n* Full or partial dentures wearers.\n* Current orthodontic treatment.\n* Smokers or those who have a recent smoking history, including e-cigarettes.\n* Diabetics.\n* Have had a dental prophylaxis in the month prior to enrolment or have one scheduled prior to the end of the study.\n* Medical condition and\u002For regular use of any medication which might affect the outcome of the study, as determined by the study dentist, principally a course of anti-inflammatory, antimicrobial or statin drugs within 4 weeks of screening.\n* Taking dietary supplements (e.g. multivitamins, antioxidants, fish oils, etc.).\n* Known allergy to any ingredient in study products.\n* The participant is a Unilever employee or a member of the study team.\n* Any participant who, in the judgement of the investigator, should not participate in the study.",true,"ALL","18 Years",{"count":20,"type":21},150,"ESTIMATED","INTERVENTIONAL",[24],"NA","The primary objective of this clinical study is to evaluate the impact on gingival health when participants switch to a fluoride toothpaste without gum-health actives for 4 weeks after using a proven gum-health toothpaste for 13 weeks.",[27,28,29],"Gingival Inflammation","Gingival Bleeding","Dental Plaque","RECRUITING","2026-04-29",{"date":33,"type":34},"2026-04-30","ACTUAL",{"date":36,"type":34},"2026-02-27",{"date":38,"type":21},"2026-08",{"name":40,"class":41},"Unilever R&D","INDUSTRY",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":22,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":61,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":42},"100614521","the-effect-of-cosmetic-formulations-on-the-appearance-of-grey-hair-100614521","NCT07280676","The Effect of Cosmetic Formulations on the Appearance of Grey Hair.","The Effect of Cosmetic Formulations on the Appearance of Gray Hair","Inclusion Criteria:\n\n* Healthy Female or Male between the ages of 25 and 60 years old, both inclusive at the time of consent.\n* Of any race and ethnicity.\n* Able to read and understand all study instructions and any other relevant study documents and understand the test procedures (in English) and able to provide a free decision about participating in the study.\n* Has 15 - 35% naturally gray hair\n* Available to come to all study visits.\n\nExclusion Criteria:\n\n* Individuals with any relevant past or present medical history which may affect the study results or may lead to increased risk to the participant in the judgement of the Investigator or designee, including a history of cancer, insulin-dependent diabetes, acute or chronic renal insufficiency, chronic inflammatory disorders (arthritis, osteoarthritis, inflammatory bowel disease, colitis, etc.), asthma (not including exercise-induced asthma), epilepsy, uncontrolled hyperthyroidism, or uncontrolled hypothyroidism. Participants who have well controlled hyperthyroidism and hypothyroidism (stable medication for greater than 6 months) will be permitted.\n* Pattern hair loss (Savin ≥ 2 for females, or Hamilton-Norwood ≥IV \\& excluding vertex hair loss for males) or any history of hair loss for medical reasons, including, but not limited to, alopecia areata, alopecia universalis, alopecia totalis or telogen effluvium.\n* Individuals that are sensitive\u002Fallergic to any of the ingredients in any of the test products adhesives, tattoo pigments\u002Fink, or metals used in needles (i.e., chromium or nickel).\n* Individuals with an immunological disorder or bloodborne disease (e.g. HIV, HBC, AIDS, multiple sclerosis, Crohn's disease, rheumatoid arthritis) or currently using oral or systemic immunosuppressive medications and biologics (e.g., azathioprine, belimumab, Cimzia®, Cosentyx®, cyclophosphamide, cyclosporine, Enbrel®, Humira®, Imuran®, Kineret®, mycophenolate mofetil, methotrexate, Orencia®, prednisone, Remicade®, Rituxan®, Siliq™, Simponi®, Stelara®, Taltz®) and\u002For undergoing radiation or chemotherapy as determined by study documentation.\n* Individuals having started a long-term medication within the last 6 months or have changed brand, manufacture, or dosage of a long-term medication.\n* Individuals currently using or having regularly used corticosteroids (known as steroids), systemically or topically, topically anywhere on the body, except nasal, and\u002For ocular use is acceptable within the past 4 weeks (including but not limited to betamethasone, clobetasol, desoximetasone, diflorasone, fluocinonide, fluticasone, mometasone, halcinonide, and halobetasol) (see list in Appendix 8)\n* Individuals currently taking any other medications which, in the opinion of the Investigator or designee, may interfere with the study (e.g. prescription anti-inflammatory drugs, anticoagulants, etc.).\n* Individuals with hemophilia, anemia, or any other blood clotting disorder.\n* Individuals who have a history of systemic granulomatous diseases, active or inactive, (e.g., sarcoidosis, Wegener's granulomatosis, tuberculosis) or connective tissue diseases (e.g., lupus, dermatomyositis).\n* Individuals who are involved in any aspect of administration or an employee of Sponsor or testing facility.\n* Individuals currently used\u002Ftaking or have used\u002Ftaken within the last 3 months any topical or ingestible anti-gray hair or hair growth supplements\u002Ftreatments (examples: Arey: Not Today, Anti-gray hair supplements, Heyhair: Gray Escape Advanced Anti-Gray Hair Growth Supplements, Vegamour: GRO Ageless Gray Delay Hair Supplements, Elon Essentials, R3 Extra Strength etc.).\n\nThe Investigator may exclude participants for other conditions, factors, or medications that they believe may affect the response of the skin or the interpretation of the test results.","25 Years","60 Years",{"count":53,"type":21},380,[24],"This study is a 6-month (180 days) single-center, double blind study designed to explore the effect of two cosmetic products on the appearance of gray hair.",[57],"Hair Graying",[59,60],"Hair appearance","Hair graying",{"date":33,"type":34},{"date":63,"type":34},"2025-12-15",{"date":65,"type":21},"2026-12",{"name":40,"class":41},{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":4,"eligibilityCriteria":73,"healthyVolunteers":16,"sex":74,"minAge":18,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":22,"phases":78,"briefSummary":79,"conditions":80,"keywords":4,"overallStatus":82,"whyStopped":4,"lastUpdateSubmitDate":83,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":42},"100585204","the-effect-of-cosmetic-products-on-skin-brightening-100585204","NCT06899321","The Effect of Cosmetic Products on Skin Brightening","A Clinical Study to Evaluate Test Products for Skin Brightening Benefit Under Controlled UV Exposure, in a 6-week Study Design","Inclusion Criteria:\n\n* Healthy female adult participants in general good health as determined from a recent medical history.\n* Participants in the age group of 18-45 years as on the day of enrolment (both ages inclusive).\n* Participants having very little hair, no burns, no cut\u002Fabrasion; no moles\u002Ftattoo\u002Fbirth marks\u002Fburn marks on the test sites\u002Fareas as identified on screening.\n* Participants with long and broad forearms.\n* Participants having skin photo-type IV and V.\n* Participants with Spectrophotometer L\\* value- 45 to 55 (both values included) on the identified test sites on the volar forearm.\n* Participants having uniform skin color and no sunburn\u002F erythema on the test sites.\n* Participants who do not have very dry or scaly skin, uneven skin tone on their volar forearms or no other signs of significant local irritation or skin disease like psoriasis.\n* Participants who agree to refrain from using pumice stone, scrubber while bathing during the study.\n* Participants who are willing to avoid direct sun exposure to the test sites.\n* Participants who have not participated in any clinical product evaluation test within past 1 month.\n* Participants able to read and sign an appropriate informed consent form indicating her willingness to participate and agree to come for regular study visits.\n* Participants willing to abide by and comply with the study protocol.\n* Participants willing to use umbrella \\& wear full covered attire if she has to go in sun.\n* Participants who are willing not to participate in any other clinical study during participation in the current study.\n\nExclusion Criteria:\n\n* Participants with a known history or present condition of allergic response to any sunscreen products, cosmetic products, bathing soaps, detergent powder or medicine.\n* Participants who have outdoor job, extremely physical (manual) job which could cause excessive sun exposure or sweating\n* Participants who are smokers.\n* Menopausal women.\n* Participants having active skin diseases which will interfere with the test readings.\n* Participants on oral and topical medications (e.g Steroids, anti-oxidant, antibiotics) which will compromise the study.\n* Systemic treatment which may modify the cutaneous state on the day of inclusion or in the previous 30 days, including retinoid therapy.\n* Participants who are pregnant, lactating or nursing.\n* Intense sun exposure\u002F photo allergenicity\u002Ftoxicity.\n* Chronic illness which may influence the cutaneous state.\n* Participants participating in any other cosmetic or therapeutic trial.\n* Participants with any underlying uncontrolled medical illness including diabetes mellitus, hypertension, liver disease or history of alcoholism, HIV, hepatitis, or any other serious medical illness that will pose a health risk due to study participation as per investigator's discretion.\n* For female participants only: be pregnant, planning pregnancy or lactating\u002Fnursing. Urine pregnancy testing (UPT) will be performed at the time of screening.","FEMALE","45 Years",{"count":77,"type":21},34,[24],"This is a single centre, single cell, blinded study designed to evaluate the effect of 5 cosmetic products on skin brightening, skin hydration and skin barrier function of the volar forearm after controlled UV exposure as compared to baseline and a no-treatment control.",[81],"Skin Brightening","NOT_YET_RECRUITING","2025-03-20",{"date":85,"type":34},"2025-03-27",{"date":87,"type":21},"2025-03",{"date":89,"type":21},"2025-05",{"name":40,"class":41},""]