[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad Europea de Madrid\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":476},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,18,0,[8,46,70,97,121,149,170,198,225,250,268,289,311,339,366,396,423,447],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100642961","clinical-efficacy-of-a-multicomponent-exercise-and-comprehensive-geriatric-assessment-program-frailap-in-frail-older-adults-within-primary-care-a-randomized-controlled-trial-100642961",false,"NCT07643064","Clinical Efficacy of a Multicomponent Exercise and Comprehensive Geriatric Assessment Program (FRAIL+AP) in Frail Older Adults Within Primary Care: A Randomized Controlled Trial","FRAIL+AP","Inclusion Criteria:\n\n* Community-dwelling adults aged 70 years or older.\n* Ability and willingness to provide written informed consent.\n* Medical clearance to participate in low-to-moderate intensity physical exercise.\n* Presence of frailty or pre-frailty defined by meeting at least two of the following criteria:\n* Functional independence sufficient to participate in the intervention (Barthel Index \\>80.\n* FRAIL Scale score ≥ 1.\n* Short Physical Performance Battery (SPPB) score \\\u003C 10.\n* Gait speed \\\u003C 0.8 m\u002Fs.\n* Timed Up and Go (TUG) test \\> 12 seconds.\n* Registered at one of the participating primary care centers.\n\nExclusion Criteria:\n\n* Absolute contraindications to physical exercise, including recent acute myocardial infarction, unstable angina, severe uncontrolled cardiovascular disease, or severe uncorrected aortic stenosis.\n* Severe cognitive impairment preventing comprehension of study procedures or exercise instructions.\n* Severe psychiatric disorders interfering with participation.\n* Absence of a legally authorized representative when required.\n* Severe uncontrolled behavioral disturbances.\n* Any acute or chronic medical condition considered by the investigators to make participation unsafe.\n\nDiscontinuation Criteria:\n\n* Failure to attend the initial mandatory health education workshop.\n* Attendance at fewer than 6 of the 12 scheduled supervised exercise sessions.\n* Development of an acute medical condition that results in a temporary or permanent contraindication to physical activity.\n* Participant withdrawal of informed consent.","ALL","70 Years",{"count":19,"type":20},200,"ESTIMATED","INTERVENTIONAL",[23],"NA","Frailty is a multidimensional clinical syndrome associated with increased vulnerability to adverse health outcomes in older adults. Despite strong evidence supporting multicomponent exercise interventions, their implementation in primary care settings remains limited.\n\nThis randomized controlled trial aims to evaluate the efficacy of the FRAIL+AP program, which integrates Comprehensive Geriatric Assessment (CGA) with a 12-week multicomponent exercise intervention, including visual-spatial gait retraining using the Tapiz Fisior system.\n\nThe study will assess whether this intervention improves frailty status, physical performance, and functional independence, while reducing falls among community-dwelling older adults compared to standard care.",[26],"Frail Elderly",[28,29,30,31,32],"exercise","frailty","elderly","physiotherapy","primary care","RECRUITING","2026-06-07",{"date":36,"type":37},"2026-06-11","ACTUAL",{"date":39,"type":37},"2026-05-28",{"date":41,"type":20},"2026-12-31",{"name":43,"class":44},"Universidad Europea de Madrid","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":53,"targetDuration":4,"studyType":21,"phases":55,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":45},"100638425","effectiveness-of-combined-concentric-and-eccentric-aerobic-exercise-on-a-treadmill-in-patients-with-copd-a-randomized-clinical-trial-100638425","NCT07627035","EFFECTIVENESS OF COMBINED CONCENTRIC AND ECCENTRIC AEROBIC EXERCISE ON A TREADMILL IN PATIENTS WITH COPD: A RANDOMIZED CLINICAL TRIAL.","Inclusion Criteria: • Subjects \\>18 years old.\n\n* Present with dyspnea grade 2-3 on the mMRC scale.\n* Sufficient cognitive and functional level to understand, learn, and carry out the exercise program.\n* No contraindications to physical training.\n* Active participants.\n\nExclusion Criteria: • Recent cardiovascular events such as congestive heart failure, angioplasty or cardiac surgery within the last four weeks, valvular abnormalities requiring surgical correction, myopericarditis, or exercise-induced ventricular arrhythmias.\n\n* Renal failure requiring dialysis.\n* Patients with uncontrolled bronchospasm due to intrinsic asthma.\n* Patients undergoing chemotherapy after surgery.\n* Severe exercise intolerance due to untreated cardiac arrhythmias, ischemia during low-intensity exercise (unstable angina), severe pulmonary hypertension, or heart failure (NYHA class III or IV).\n* Pulmonary embolism with anticoagulant therapy for less than 5 days.","18 Years",{"count":54,"type":20},40,[23],"The aim of this study is to demonstrate the effectiveness of combined concentric and eccentric aerobic training in subjects with COPD, in terms of strength, lung capacity, functionality, and short-term health quality. A randomized, examiner-blinded clinical trial has been designed for this purpose, following the CONSORT guidelines for clinical trials and the ethical principles of the Declaration of Helsinki. A total sample of 40 subjects has been estimated. The study is aimed at patients diagnosed with mild or moderate COPD. A program of 12 group sessions will be conducted over 4 weeks. Each session will last 75 minutes and will include strength exercises and respiratory physiotherapy, common to all subjects. The interval aerobic training will depend on the assigned group: treadmill with negative and positive (or neutral) incline (experimental group), treadmill with positive incline and\u002For cycle ergometer (control group). The following variables will be measured on the first and last day of treatment, as well as one month after the intervention ends: thickness, cross-sectional area, and ultrasound intensity of the rectus femoris muscle; diaphragmatic excursion and thickness; 5 sit to stand test; get up and go test; Borg scale; maximum respiratory pressures; grip strength in both hands and maximum quadriceps strength; spirometric assessment of FEV1 and SF-12 health quality questionnaire.",[58,59,60],"COPD (Chronic Obstructive Pulmonary Disease)","Pulmonary Rehabilitation","Eccentric Exercise Training","NOT_YET_RECRUITING","2026-05-31",{"date":64,"type":37},"2026-06-04",{"date":66,"type":20},"2026-09",{"date":68,"type":20},"2028-09",{"name":43,"class":44},{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":76,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":21,"phases":82,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":95,"locationsCount":96},"100480731","exercise-in-adolescents-with-cancer-100480731","NCT05539794","Exercise in Adolescents With Cancer","Exercise Intervention for Adolescents With Cancer (EXERCADOL): A Randomized Controlled Trial","EXERCADOL","Inclusion Criteria:\n\n* Newly diagnosed with a malignant extracranial tumour\n* Not having received any therapy--except surgery--at diagnosis\n* Adequate health status (Karnofsky\u002FEastern Cooperative Oncology Group scale score ≥50\u002F2)\n* To understand Spanish language and provide written informed consent.\n\nExclusion Criteria:\n\n* Life expectancy \\\u003C3 months\n* Comorbidity\u002Facute condition contraindicating exercise practice","12 Years","19 Years",{"count":81,"type":20},136,[23],"The investigators will study the effects of an supevised exercise intervention along the duration of intensive treatment (neoadjuvant \\[solid tumours\\]\u002Fintense chemotherapy \\[leukemias\\], expected median duration 5-6 months) on several health-related variables. Participants will be recruited from 4 hospitals in Madrid (Spain). Inclusion criteria: male\u002Ffemale aged 12-19 years, newly diagnosed--or relapse of-- a malignant extracranial tumour; not having received any type of therapy--except surgery--at the time of diagnosis; adequate health status (Karnofsky\u002FEastern Cooperative Oncology Group scale score ≥50\u002F≤2); to understand Spanish language and to provide written informed consent. The investigators will recruit ≥136 participants and conduct a randomised controlled trial. The intervention group will follow a supervised concurrent exercise program from the start to the end of intensive treatment. The exercise intervention will be performed in the hospital gymnasium or in the patients' ward (during neutropenic phases), and will also include supervised online sessions. Additionally, the intervention group will perform include inspiratory muscle training. The following outcomes will be assessed at baseline (diagnosis), end of treatment, and at 3-month follow-up in all participants: echocardiography-determined left ventricular function (primary outcome); and other echocardiography-determined variables, cardiac biomarkers, blood pressure, blood lipids, body composition, physical activity levels, energy intake, cardiorespiratory fitness, muscle strength, functional mobility, health-related quality of life, cancer-related fatigue, clinical variables, and potential biological underpinnings of exercise multisystemic benefits (metabolic and inflammatory markers, plasma proteome, gut microbiome, and immune function).",[85],"Adolescent Cancer",[87,88,89],"cancer","lifestyle","cardiac function",{"date":91,"type":37},"2026-06-01",{"date":93,"type":37},"2022-04-15",{"date":41,"type":20},{"name":43,"class":44},2,{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":105,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":106,"targetDuration":4,"studyType":21,"phases":108,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":4},"100636324","foam-roller-compared-to-massage-on-reducing-calf-muscle-tone-in-healthy-subjects-100636324","NCT07564206","Foam Roller Compared to Massage on Reducing Calf Muscle Tone in Healthy Subjects","Effect of Foam Roller Compared to Massage on Reducing Calf Muscle Tone in Healthy Subject","FRTONE","Inclusion Criteria:\n\n1. Age: Participants aged between 18 and 45 years.\n2. Health Status: Healthy individuals with no prior musculoskeletal conditions in the lower limbs.\n3. Pain-Free: Participants should not have had pain in the gastrocnemius or Achilles tendon in the last 3 months.\n4. Willingness: Participants must provide informed consent and be available for the intervention and necessary evaluations.\n\nExclusion Criteria:\n\n1. Musculoskeletal Conditions: Individuals with any pathologies in the calf muscles (gastrocnemius, soleus) or Achilles tendon.\n2. Vascular or Neurological Issues: Participants with vascular diseases or neurological disorders that may interfere with the interventions or muscle response.\n3. Skin Conditions: Exclusion of participants with skin alterations, infections, or open wounds in the area of intervention.\n4. Pregnancy: Women who are pregnant.\n5. Sensitivity Issues: Participants with altered sensitivity in the lower limbs or any condition that may affect the response to the techniques.\n6. Non-Compliance: Individuals who do not provide informed consent or are not available for the required evaluations.",true,{"count":107,"type":20},20,[23],"Objective: This study aims to compare the effects of two techniques-foam rolling (FR) and therapeutic massage-on reducing the muscle tone in the calf muscles (gastrocnemius and soleus) of healthy individuals.\n\nMethods: A randomized, controlled crossover design was used with 40 healthy participants (aged 18-45). Participants were randomly assigned to either a foam roller or a therapeutic massage group. The interventions were applied to the dominant leg, and muscle tone was measured pre- and post-intervention using a MyotonPro device. The primary outcome was muscle tone (Hz), and secondary outcomes included muscle stiffness (N\u002Fm) and elasticity (D \\[log\\]).\n\nResults: The study will assess the effectiveness of each intervention on muscle tone, stiffness, and elasticity. It aims to determine whether foam rolling is as effective or superior to traditional massage in reducing calf muscle tone.\n\nConclusion: This research will contribute to understanding the efficacy of foam rolling as a self-administered technique for muscle tone reduction and its potential application in clinical and athletic settings",[111,112],"Muscle Tone","Healthy Adult","2026-04-26",{"date":115,"type":37},"2026-05-04",{"date":117,"type":20},"2026-05-15",{"date":119,"type":20},"2026-07-15",{"name":43,"class":44},{"id":122,"slug":123,"hasResults":11,"nctId":124,"briefTitle":125,"officialTitle":126,"acronym":127,"eligibilityCriteria":128,"healthyVolunteers":11,"sex":16,"minAge":129,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":133,"briefSummary":134,"conditions":135,"keywords":137,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":141,"lastUpdatePostDateStruct":142,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":4},"100631911","effects-of-an-habit-ile-based-intervention-in-children-with-cerebral-palsy-100631911","NCT07506837","Effects of an HABIT-ILE-Based Intervention in Children With Cerebral Palsy","Effects of Intensive Motor Control-Based Therapy for Upper and Lower Extremities in Children With Cerebral Palsy","UEM-HABITILE","Inclusion Criteria:\n\n* Children with a diagnosis of cerebral palsy (hemiparesis or diparesis).\n* Age 6 to 13 years.\n* Moderate cognitive impairment or cognitive status compatible with the ability to follow verbal instructions.\n* Ability to participate in an intensive summer camp-format rehabilitation program.\n* Parent\u002Flegal guardian able to provide informed consent and complete parent-\u002Ftutor-reported outcome measures.\n\nExclusion Criteria:\n\n* Medical or orthopedic condition that contraindicates participation in intensive physical rehabilitation activities.\n* Unstable neurological or medical condition (e.g., uncontrolled seizures) that may interfere with safe participation.\n* Severe cognitive or behavioral impairment preventing comprehension of basic verbal instructions or safe participation in group activities.\n* Contraindication to study assessment procedures, including physiological testing or DEXA body composition assessment.\n* Participation in another concurrent intensive rehabilitation program during the study comparison period.\n* Any condition that, in the investigators' judgment, may compromise safety, adherence, or outcome assessment validity.","6 Years","13 Years",{"count":132,"type":20},30,[23],"This interventional study will evaluate the effects of an intensive HABIT-ILE-based camp on cardiorespiratory measures and body composition in children with cerebral palsy. Although intensive motor control-based therapies such as HABIT\u002FHABIT-ILE have shown functional benefits, the novelty of this study is the assessment of energy expenditure during functional tasks and post-intervention changes in body composition. Participants will attend a summer camp-format intervention delivering 90 hours of upper and lower extremity training over 15 days (6 hours\u002Fday), supervised by trained rehabilitation staff in a playful, progressive group setting. The program includes bimanual activities, gait and stair tasks, functional strengthening, and whole-body games, with fatigue prevention strategies.Assessments will be performed at baseline and immediately after the camp in July 2027, with follow-up at 6 months (January 2028). Outcomes include functional performance, parent-reported function, low-intensity task-related energy expenditure measured in a physiology laboratory, and body composition measured by DEXA at Universidad Europea de Madrid",[136],"Cerebral Palsy",[136,138,139,140],"HABIT-ILE","Body Composition","Energy Expenditure","2026-03-28",{"date":143,"type":37},"2026-04-02",{"date":145,"type":20},"2027-03-01",{"date":147,"type":20},"2028-01-01",{"name":43,"class":44},{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":4,"eligibilityCriteria":155,"healthyVolunteers":105,"sex":16,"minAge":52,"maxAge":156,"enrollmentInfo":157,"targetDuration":4,"studyType":21,"phases":159,"briefSummary":160,"conditions":161,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":163,"lastUpdatePostDateStruct":164,"startDateStruct":166,"completionDateStruct":167,"leadSponsor":169,"locationsCount":4},"100630994","effects-of-vibrational-therapy-on-pelvic-floor-muscle-strength-and-tone-in-healthy-women-100630994","NCT07494903","Effects of Vibrational Therapy on Pelvic Floor Muscle Strength and Tone in Healthy Women","Effects of Mechanical Vibration Applied to the Pelvic Floor Musculature: A Quasi-Experimental Study","Inclusion Criteria:\n\n* Throughout the intervention (ongoing during each session) and Post-intervention (after 8 weeks of treatment).\n\nExclusion Criteria:\n\n* 1\\. Urogenital Infections: Presence of any active urogenital infections. 2. Abdominal or Pelvic Surgery: History of abdominal or pelvic surgery. 3. Active Menstruation: Women who are menstruating at the time of the study. 4. Breastfeeding: Participants who are actively breastfeeding. 5. Mictrurition Symptoms: Presence of any urinary symptoms. 6. Pain: Pain upon palpation of the central fibrous nucleus of the perineum. 7. Sensory Alterations: Presence of altered sensitivity such as hypoalgesia, hyperalgesia, or allodynia.\n\n  8\\. Spinal Lesions: History of spinal cord injuries. 9. Neurological Conditions: Any neurological disorders. 10. Pelvic Organ Prolapse: Diagnosed prolapse of pelvic organs. 11. Obesity: Body Mass Index (BMI) ≥ 30 kg\u002Fm². 12. Active Oncology Treatment: Any current or recent cancer treatments. 13. Pregnancy: Women who are pregnant. 14. Pelvic Floor Pathologies: Diagnosed pelvic floor dysfunctions. 15. Ongoing Pelvic Floor Treatment: Participants currently receiving active pelvic floor treatments.\n\n  16\\. Dermatological Pathologies: Any active vulvar dermatological conditions.","45 Years",{"count":158,"type":20},60,[23],"This quasi-experimental study aims to evaluate the effects of mechanical vibration applied to the pelvic floor musculature in healthy women aged 18-45. The intervention involves vibrational therapy targeting the central fibrous nucleus of the perineum, with the goal of assessing changes in muscle tone, strength, and biomechanical properties. The study will also examine the tolerance to this technique, with data collected at baseline and after 8 weeks of treatment.",[162],"Healhty","2026-03-20",{"date":165,"type":37},"2026-03-27",{"date":91,"type":20},{"date":168,"type":20},"2026-12-01",{"name":43,"class":44},{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":176,"eligibilityCriteria":177,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":178,"targetDuration":4,"studyType":21,"phases":180,"briefSummary":181,"conditions":182,"keywords":184,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":190,"lastUpdatePostDateStruct":191,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":197,"locationsCount":45},"100629101","impact-of-hypertrophy-oriented-resistance-training-on-muscle-mass-and-quality-of-life-in-patients-with-unresectable-pancreatic-cancer-100629101","NCT07470268","Impact of Hypertrophy-oriented Resistance Training on Muscle Mass and Quality of Life in Patients With Unresectable Pancreatic Cancer","Impact of Hypertrophy-oriented Resistance Training on Muscle Mass and Quality of Life in Patients With Unresectable Pancreatic Cancer (HY-PANC): Study Protocol for a Randomized Controlled Trial.","HY-PANC","Inclusion Criteria:\n\n* Diagnosis of locally advanced or metastatic unresectable pancreatic cancer\n* Undergoing chemotherapy or immunotherapy treatment\n* Age ≥ 18 years\n* ECOG score ≤ 2\n\nExclusion Criteria:\n\n* Any relative or absolute contraindication that prevents the performance of training or physical tests.\n* Diagnosis of other types of primary cancer\n* Inability to understand Spanish for proper comprehension of the informed consent and questionnaires",{"count":179,"type":20},10,[23],"To determine the efficacy of a 12-week supervised, hypertrophy-oriented strength training program in preserving skeletal muscle mass, physical function, and quality of life in patients with unresectable pancreatic cancer compared to standard care.",[183],"Pancreatic Cancer",[185,186,187,188,189],"physical activity","physical function","body composition","lean mass","chemotherapy","2026-03-16",{"date":192,"type":37},"2026-03-18",{"date":194,"type":20},"2026-09-01",{"date":196,"type":20},"2027-09-01",{"name":43,"class":44},{"id":199,"slug":200,"hasResults":11,"nctId":201,"briefTitle":202,"officialTitle":203,"acronym":204,"eligibilityCriteria":205,"healthyVolunteers":105,"sex":16,"minAge":52,"maxAge":206,"enrollmentInfo":207,"targetDuration":4,"studyType":21,"phases":209,"briefSummary":210,"conditions":211,"keywords":213,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":217,"lastUpdatePostDateStruct":218,"startDateStruct":220,"completionDateStruct":222,"leadSponsor":224,"locationsCount":45},"100623221","physiological-responses-to-manual-pressure-in-healthy-adults-100623221","NCT07393815","\"Physiological Responses to Manual Pressure in Healthy Adults\"","Physiological Responses to Graded Manual Pressure in Healthy Adults: a Randomized Experimental Study on Autonomic, Hormonal, Sensory and Vascular Outcomes","VALIRAT1","Inclusion Criteria:\n\n* Age 18-65 years.\n* Healthy volunteers without diagnosed cardiovascular, neurological or severe musculoskeletal disorders.\n* No significant pain or pathology in the cervical, shoulder or upper back region that would interfere with pressure application.\n* Ability to understand the study procedures and to provide written informed consent.\n* Availability to attend the experimental session and the DEXA visit.\n\nExclusion Criteria:\n\n* History of major cardiovascular disease (e.g., ischemic heart disease, heart failure, clinically significant arrhythmias, uncontrolled hypertension, stroke or transient ischemic attack).\n* Neurological disorders affecting pain perception or autonomic function.\n* Acute or chronic musculoskeletal conditions in the cervical or shoulder region that contraindicate manual pressure on the upper trapezius.\n* Coagulation disorders or high-dose anticoagulant\u002Fantiplatelet therapy that increases bleeding risk.\n* Dermatologic conditions or skin lesions at sensor placement or pressure application sites.\n* Pregnancy or suspected pregnancy (due to DEXA scan).\n* Regular use of medications with a major impact on autonomic or cardiovascular responses (e.g., beta-blockers, antiarrhythmics) that cannot be paused according to medical judgement.\n* Substance abuse or acute alcohol\u002Fdrug intake in the 24 hours prior to the experimental session.\n* Any other condition that, in the opinion of the investigators, may compromise safety or compliance.","65 Years",{"count":208,"type":20},90,[23],"This randomized experimental study will investigate how different intensities and application patterns of manual pressure applied to the upper trapezius muscle affect physiological responses in healthy adults. Participants will be randomly assigned to one of three groups: (A) graded sustained pressure at a single point over the upper trapezius, (B) graded longitudinal kneading over a defined area of the upper trapezius, or (C) three standardized manual therapy protocols with increasing pressure (manual lymphatic drainage, light-pressure massage and moderate-pressure massage).\n\nIn groups A and B, five individualized pressure levels (0, 25, 50, 75 and 95% of each participant's pressure pain threshold) will be delivered for 2 minutes each in a single session. In group C, each participant will receive the three manual therapy protocols in separate randomized sessions. Autonomic (heart rate and heart rate variability), hormonal (capillary cortisol and VEGF in group C), sensory (mechanical pain thresholds), hemodynamic (blood pressure) and, in group C, vascular (left common carotid artery ultrasound) responses will be recorded before and after the interventions. The study will provide dose-response and mechanistic information to inform safer and more individualized manual therapy protocols.",[212],"Healthy Participants",[214,215,216],"Autonomic Nervous System","Manual Therapy","Pain","2026-02-02",{"date":219,"type":37},"2026-02-06",{"date":221,"type":20},"2026-03",{"date":223,"type":20},"2026-07",{"name":43,"class":44},{"id":226,"slug":227,"hasResults":11,"nctId":228,"briefTitle":229,"officialTitle":230,"acronym":231,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":21,"phases":236,"briefSummary":237,"conditions":238,"keywords":240,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":247,"leadSponsor":249,"locationsCount":45},"100598054","act-based-intervention-for-problem-gambling-100598054","NCT07066501","ACT-Based Intervention for Problem Gambling","Efficacy of a Group Intervention Grounded in Acceptance and Commitment Therapy (ACT) to Address Problem Gambling in Youth: A Randomized Clinical Trial","jugACT","Inclusion Criteria:\n\n* Age between 18 and 25 years\n* Score ≥ 3 on the Problem Gambling Severity Index (PGSI)\n* Comprehension of Spanish, online connection, and signed consent\n\nExclusion Criteria:\n\n* In active psychological or pharmacological treatment for gambling disorder\n* Having received ACT-based psychological treatment in the last 6 months\n* Problematic substance use: CAGE Adapted to Include Drugs Questionnaire (CAGE-AID) score ≥ 3\n* Difficulty consistently attending online sessions","25 Years",{"count":235,"type":20},72,[23],"The goal of this randomized clinical trial is to study if Acceptance and Commitment Therapy (ACT) is effective to treat Problem Gambling in young adults.The main questions it aims to answer are:\n\n* Does ACT therapy improve health and gambling behavior?\n* Are the clinical improvements of youth with gambling disorder receiving ACT-based intervention significantly greater than the clinical improvements of youth with gambling disorder on the waiting list?\n\nResearchers will assess whether changes in health, gambling behavior, and other psychological variables are observed after eight weeks of therapy.\n\nParticipants will:\n\n* Attend weekly online group sessions for 8 weeks\n* Learn new tools that they will put into practice after the sessions\n* Be required to complete evaluation questionnaires before and after the intervention and at the 3- and 6-month follow-up",[239],"Problem Gambling",[239,241,242],"Gaming Disorder","Psychological Inflexibility","2025-07-15",{"date":245,"type":37},"2025-07-18",{"date":221,"type":20},{"date":248,"type":20},"2027-07",{"name":43,"class":44},{"id":251,"slug":252,"hasResults":11,"nctId":253,"briefTitle":254,"officialTitle":255,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":233,"enrollmentInfo":256,"targetDuration":4,"studyType":21,"phases":258,"briefSummary":259,"conditions":260,"keywords":261,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":267,"locationsCount":45},"100598053","brief-act-intervention-for-problem-gambling-a-pilot-study-100598053","NCT07066488","Brief ACT Intervention for Problem Gambling: A Pilot Study","Brief Group Intervention Based on Acceptance and Commitment Therapy (ACT) for Problem Gambling: A Pilot Study",{"count":257,"type":20},5,[23],"The goal of this pilot study is to learn if Acceptance and Commitment Therapy (ACT) works to treat Problem Gambling in young adults.The main questions it aims to answer are:\n\n* Does ACT therapy improve health and gambling behavior?\n* Is an 8-week online group therapy format viable for youth with gambling problems? Researchers will assess whether changes in health, gambling behavior, and other psychological variables are observed after eight weeks of therapy.\n\nParticipants will:\n\n* Attend weekly online group sessions for 8 weeks\n* Learn new tools that they will put into practice after the sessions\n* Be required to complete evaluation questionnaires before and after the intervention and at the 3- and 6-month follow-up",[239],[239,241,242],"2025-07-04",{"date":243,"type":37},{"date":265,"type":20},"2025-10-01",{"date":41,"type":20},{"name":43,"class":44},{"id":269,"slug":270,"hasResults":11,"nctId":271,"briefTitle":272,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":274,"targetDuration":4,"studyType":21,"phases":276,"briefSummary":277,"conditions":278,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":281,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":45},"100524497","effects-of-an-act-based-psychological-treatment-in-patients-with-chronic-kidney-disease-100524497","NCT06109493","Effects of an ACT-based Psychological Treatment in Patients With Chronic Kidney Disease","Inclusion Criteria:\n\n* Patients with chronic kidney disease on haemodialysis\n* Older than 18 years-old\n* At least 3 months on haemodialysis\n* HADS Global Scale Score ≥14\n\nExclusion Criteria:\n\n* Diagnosis of severe or chronic mental disorder, mental retardation and cognitive impairment, or disabling illness.\n* Antidepressant drugs consume\n* Insufficient understanding of Spanish.\n* Patients who are in the Advanced Chronic Kidney Disease Unit\n* Receiving other psychological treatment",{"count":275,"type":20},104,[23],"Investigation of the efficacy of Acceptance and Commitment Therapy (ACT) for the psychological treatment of patients with chronic kidney disease.",[279,280],"Chronic Kidney Diseases","Depression","2025-04-22",{"date":283,"type":37},"2025-04-23",{"date":285,"type":37},"2023-11-01",{"date":287,"type":20},"2026-06-30",{"name":43,"class":44},{"id":290,"slug":291,"hasResults":11,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":105,"sex":296,"minAge":52,"maxAge":206,"enrollmentInfo":297,"targetDuration":4,"studyType":21,"phases":299,"briefSummary":300,"conditions":301,"keywords":4,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":303,"lastUpdatePostDateStruct":304,"startDateStruct":306,"completionDateStruct":308,"leadSponsor":310,"locationsCount":45},"100573445","effect-of-a-specific-hand-intervention-in-women-with-arthralgia-secondary-to-hormone-therapy-following-breast-cancer-100573445","NCT06746376","Effect of a Specific Hand Intervention in Women With Arthralgia Secondary to Hormone Therapy Following Breast Cancer.","Effect of a Specific Hand Intervention Program With Strength and Manipulative Dexterity Exercises in Women With Arthralgia Secondary to Hormone Therapy Following Breast Cancer.","Inclusion Criteria\n\nExperiencing hand arthralgia as a result of hormone therapy (aromatase inhibitors or tamoxifen) following breast cancer.\n\nAbility to communicate pain levels effectively. Ability to follow simple instructions to participate in the intervention and assessments.\n\nExclusion Criteria Participants requiring any medication changes during the study period that could influence pain levels (increase or decrease).\n\nConcurrent physiotherapy or occupational therapy specifically targeting the hand during the study.\n\nPre-existing diagnosis of arthritis or osteoarthritis in the hand before starting hormone therapy.\n\nPresence of systemic diseases associated with hand arthralgia. Neurological conditions affecting hand movement.","FEMALE",{"count":298,"type":20},32,[23],"This study aims to evaluate the impact of a 12-week hand exercise program on pain, manual dexterity, and hand function in women experiencing hand joint pain (arthralgia) due to hormone therapy after breast cancer. Participants will be randomly assigned to either an intervention group, where they will perform specific hand exercises, or a control group, which will not receive any exercise program. Pain levels, hand function, and manual dexterity will be assessed before and after the intervention using questionnaires and functional tests. The goal is to determine whether targeted hand exercises can improve pain and daily hand use in this population.",[302],"Arthralgia","2024-12-17",{"date":305,"type":37},"2024-12-24",{"date":307,"type":20},"2025-04-01",{"date":309,"type":20},"2025-11-01",{"name":43,"class":44},{"id":312,"slug":313,"hasResults":11,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":4,"eligibilityCriteria":317,"healthyVolunteers":105,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":318,"targetDuration":320,"studyType":321,"phases":4,"briefSummary":322,"conditions":323,"keywords":326,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":331,"lastUpdatePostDateStruct":332,"startDateStruct":334,"completionDateStruct":336,"leadSponsor":338,"locationsCount":45},"100569523","pain-in-subjects-with-high-capacity-cognitive-abilities-100569523","NCT06695351","Pain in Subjects with High Capacity Cognitive Abilities","Pain in Subjects with High Capacity Cognitive Abilities: a Cross Sectional Study","Inclusion Criteria:\n\n* People with a diagnosis of high cognitive abilities\n\nExclusion Criteria:\n\n* People with incapacity to answer the questionnaire\n* People that's not have a good level of Spanish language",{"count":319,"type":20},150,"1 Day","OBSERVATIONAL","In many books and website focused in high cognitive abilities talks about pain in these subjects. However, when the investigators look for in sites like pubmed there are no literature about this topic. With this study the investigators will try to know better pain experience in this population and chronic pain prevalence",[324,216,325],"High Cognitive Abilities","Prevalence",[327,216,325,328,329,330],"high cognitive abilities","Kinesiophobia","Catastrophising","giftedness","2024-11-16",{"date":333,"type":37},"2024-11-19",{"date":335,"type":20},"2024-12",{"date":337,"type":20},"2025-06",{"name":43,"class":44},{"id":340,"slug":341,"hasResults":11,"nctId":342,"briefTitle":343,"officialTitle":344,"acronym":4,"eligibilityCriteria":345,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":346,"targetDuration":4,"studyType":21,"phases":348,"briefSummary":349,"conditions":350,"keywords":354,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":358,"lastUpdatePostDateStruct":359,"startDateStruct":361,"completionDateStruct":363,"leadSponsor":365,"locationsCount":45},"100554037","respiratory-rehabilitation-based-on-eccentric-exercice-on-treadmill-after-thoracic-surgery-100554037","NCT06493877","Respiratory Rehabilitation Based on Eccentric Exercice on Treadmill After Thoracic Surgery","Respiratory Rehabilitation Based on Eccentric Exercice on Treadmill After Thoracic Surgery: a Randomized Clinical Trial","Inclusion Criteria:\n\n* Subjects \\>18 years.\n* Thoracic surgery in the previous 75 days\n* Present dyspnea grade 2 - 3 on the mMRC scale.\n* Cognitive and functional level sufficient to understand, learn and carry out the exercise program.\n* Not have contraindications to perform physical training.\n* Active collaborators.\n\nExclusion Criteria:\n\n* Severe intolerance to exertion due to untreated cardiac arrhythmias, ischemia during low intensity exercise (anginas unstable), severe pulmonary hypertension, heart failure (NYHA III or IV)\n* Pulmonary embolism with anticoagulant treatment less than 5 days.\n* Recent cardiovascular events such as congestive heart failure, angioplasties or cardiac surgeries of less than four weeks' duration, valvular alterations requiring surgical correction, myopericarditis, ventricular arrhythmias caused by exercise.\n* Kidney failure requiring dialysis.\n* Patients with uncontrolled bronchospasm due to intrinsic asthma.\n* Patients undergoing post-surgery chemotherapy treatment.\n* Adverse effects that occurred during the development of the treatment.",{"count":347,"type":20},57,[23],"Thoracic surgeries are frequent and pulmonary rehabilitation is essential, since one of the problems that these patients present is dyspnea when performing aerobic exercise, which limits improvement and in some cases causes them to abandon physical exercise. Thanks to carrying out a correct effort retraining program, combining respiratory physiotherapy with therapeutic exercise, patients with respiratory pathologies manage to improve lung capacity and ventilatory mechanics, increase muscle strength and aerobic resistance, prevent long- term complications, reduce fatigue and, ultimately, improve your quality of life.\n\nLikewise, it is important to find the most appropriate type of muscular work that produces more benefits in the short and medium term to optimize our resources.The objective of the study is to demonstrate the effectiveness of eccentric training in patients who have undergone thoracic surgery, in terms of strength, lung capacity, functionality and quality of health in the short and medium term.\n\nFor this purpose, a randomized clinical trial has been designed, with a blinded examiner, following the CONSORT guideline for clinical trials and the ethical principles of the Declaration of Helsinki. A total sample of 57 subjects has been estimated. The study is aimed at patients after scheduled thoracic surgery. A program of 12 group sessions spread over 4 weeks will be carried out. Each of them will last 75 minutes and will include strength and respiratory physiotherapy exercises, common to all subjects.\n\nAerobic interval training will depend on the group assigned: treadmill with negative slope (experimental group), treadmill with positive slope (control group 1) or cycle ergometer (control group 2). On the first and last day of treatment, as well as one month after completing the intervention, the following variables will be measured: thickness, cross-sectional area and ultrasound intensity of the rectus femoris; diaphragmatic excursion and thickness; 6 minute walk test; Borg scale; maximum respiratory pressures; sit-to-stand test; grip strength in both hands; spirometric assessment of FEV1 and SF-12 health quality questionnaire. a",[351,352,353],"Thoracic Surgery","Breathing","Muscle",[355,356,357],"\"thoracic surgery\"","\"eccentric training\"","\"pulmonary rehabilitation\"","2024-07-09",{"date":360,"type":37},"2024-07-11",{"date":362,"type":20},"2024-09",{"date":364,"type":20},"2027-09",{"name":43,"class":44},{"id":367,"slug":368,"hasResults":11,"nctId":369,"briefTitle":370,"officialTitle":371,"acronym":4,"eligibilityCriteria":372,"healthyVolunteers":11,"sex":16,"minAge":373,"maxAge":4,"enrollmentInfo":374,"targetDuration":376,"studyType":321,"phases":4,"briefSummary":377,"conditions":378,"keywords":385,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":389,"lastUpdatePostDateStruct":390,"startDateStruct":391,"completionDateStruct":393,"leadSponsor":395,"locationsCount":45},"100532846","update-on-the-detection-of-frailty-in-older-adults-100532846","NCT06218121","Update on the Detection of Frailty in Older Adults","Update on the Detection of Frailty in Older Adults: A Multicenter Cohort Machine Learning-Based Study","Inclusion Criteria:\n\nA diagnosis of signs and symptoms of frailty by a geriatric physician in the research group will be used as the primary inclusion criterion. Frailty will be assessed and diagnosed using the frailty phenotype and the Clinical Frailty Scale.\n\nExclusion Criteria:\n\n* Acute myocardial infarction in the last 3 months and\u002For unstable angina pectoris\n* Uncontrolled arrhythmia, recent thromboembolism and terminal illness.\n* Patients undergoing MMII unloading or MMSS\u002FMMII fractures in the last three months.\n* Patients with a functional gait index of 1 (Inability to walk)\n* Severe pain (7\u002F10 VAS)\n* Previous neuromuscular pathology presenting with weakness\n* Medication that does not allow the patient's actual muscle reaction to be assessed\n* Severe cognitive impairment that would prevent collaboration and understanding of the tests to be performed.\n* Cardiovascularly unstable patients and uncontrolled arterial hypertension.","62 Years",{"count":375,"type":20},500,"2 Years","The main objective is to update the diagnostic assessment of frailty by correlating several variables with the ultrasound image of the frail elderly patient.\n\nSecondarily, the investigators intend to collect and analyze data on functional capacity and quality of life variables on the evolution of musculoskeletal symptoms, as well as on pain and psychological variables. Similarly, it is intended to make a record of different profiles and subtypes of frail older adult patients to be stored in Machine Learning in order to establish therapeutic intervention plans that allow both the evaluation and treatment of patients.",[379,380,381,382,216,383,384,328,280],"Strength","Quality of Life","Functional Independence","Functionality","Sarcopenia","Anxiety",[386,387,383,388],"Frailty","Quality of life","Ultrasound","2024-07-08",{"date":358,"type":37},{"date":392,"type":37},"2024-04-20",{"date":394,"type":20},"2025-06-15",{"name":43,"class":44},{"id":397,"slug":398,"hasResults":11,"nctId":399,"briefTitle":400,"officialTitle":401,"acronym":4,"eligibilityCriteria":402,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":206,"enrollmentInfo":403,"targetDuration":404,"studyType":321,"phases":4,"briefSummary":405,"conditions":406,"keywords":410,"overallStatus":61,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":419,"completionDateStruct":421,"leadSponsor":422,"locationsCount":4},"100544473","ultrasound-study-of-the-submentonian-musculature-and-its-relationship-in-dysphagia-100544473","NCT06369337","Ultrasound Study of the Submentonian Musculature and Its Relationship in Dysphagia","Ultrasound Study of the Submentonian Musculature and Its Relationship in the Development of Dysphagia After Invasive Mechanical Ventilation: a Single-center Cohort Study","Inclusion Criteria:\n\n* • Subjects \\>18 years old.\n\n  * Having received an episode of orotracheal intubation for \\>48h\n\nExclusion Criteria:\n\n* • Congenital or acquired conditions of the Central Nervous System (CNS) such as stroke, traumatic brain injury, Parkinson's, multiple sclerosis, amyotrophic lateral sclerosis (ALS) or any other condition that may bias the attribution of dysphagia to factors other than exclusively clinical ones.\n\n  * Involvement of the cranial nerves or the Peripheral Nervous System (PNS) as well as diseases of the neuromuscular junction such as Myasthenia Gravis or any other condition that may bias the attribution of dysphagia to other factors that are not exclusively clinical.\n  * Neck morphology incompatible with exploration through ultrasound procedures.\n  * Secondary musculoskeletal injuries, including vertebral fractures, unstable extremity fractures or any condition that requires absolute bed rest as prescribed by a doctor.\n  * Malignant tumor lesions or previous head and\u002For neck surgeries.\n  * Medical-surgical history due to pathology of the larynx, oropharynx and\u002For esophagus.\n  * Diagnosis of dysphagia or swallowing disorders prior to the intubation episode with IMV.\n  * Patients unable to eat orally, at least partially.\n  * Known prior cognitive impairment upon admission to the ICU.",{"count":319,"type":20},"1 Year","Acquired dysphagia is one of the most frequent complications suffered by patients in intensive care units (ICU) after orotracheal extubation. Ultrasound has proven to be a useful method in the morphological and kinematic exploration of the main swallowing structures. AIM: to evaluate, through ultrasound procedures, the evolution of the morphology of the tongue and muscles of the floor of the mouth and the hyolaryngeal kinematics in patients intubated \\>48h and to correlate these measurements with the possible development of acquired dysphagia. The incidence of dysphagia and ICU acquired weakness (ICUAW) in subjects with \\>48h of intubation and the relative risk factors associated with baseline characteristics and clinical variables will be described. METHODOLOGY: Design: Single-center cohort study (Ramón y Cajal University Hospital). Participants: subjects \\>18 years old, admitted to an intensive care unit (ICU), with \\>48 hours of orotracheal intubation who meet eligibility criteria. Outcomes: the study of socio-demographic and clinical variables related to ICU admission will be included. The physical function variables will be analyzed through the Medical Research Council (MRC) and Functional Status Score (FSS), as well as swallowing function variables through the Volume-Viscosity Swallow (VVS-T) and Functional Oral Intake Scale scales. (FOIS) and Gugging Swallowing Screen (GUSS). Measurements will be made of the thickness and echogenicity of the submental and tongue muscles, as well as hyolaryngeal kinematics",[407,408,409],"Dysphagia, Oropharyngeal","Deglutition Disorders","Mechanical Ventilation Complication",[411,412,413,414,415],"Dysphagia","Ultrasonography","Deglutition disorders","Diagnostic Imaging","Mechanical ventilation","2024-06-27",{"date":418,"type":37},"2024-07-01",{"date":420,"type":20},"2024-06",{"date":337,"type":20},{"name":43,"class":44},{"id":424,"slug":425,"hasResults":11,"nctId":426,"briefTitle":427,"officialTitle":428,"acronym":429,"eligibilityCriteria":430,"healthyVolunteers":11,"sex":296,"minAge":233,"maxAge":431,"enrollmentInfo":432,"targetDuration":4,"studyType":21,"phases":434,"briefSummary":435,"conditions":436,"keywords":438,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":441,"lastUpdatePostDateStruct":442,"startDateStruct":443,"completionDateStruct":445,"leadSponsor":446,"locationsCount":96},"100372912","effects-of-a-physical-exercise-intervention-during-neoadjuvant-chemotherapy-in-women-with-breast-cancer-100372912","NCT04135586","Effects of a Physical Exercise Intervention During Neoadjuvant Chemotherapy in Women With Breast Cancer","Effects of a Physical Exercise Intervention at the Molecular Systemic and Tumor Level Performed During Neoadjuvant Chemotherapy in Women With Breast Cancer","NEOLIFE","Inclusion Criteria:\n\n* Diagnosed with breast carcinoma in the 'Hospital Universitario Quirónsalud de Pozuelo' (Madrid, Spain) and following neoadjuvant therapy in the aforementioned center.\n* Must have triple negative breast cancer (i.e., negative for estrogen receptors, progesterone receptors, and excess HER2 protein) of size \\> or equal to 15 mm\n\nExclusion Criteria:\n\n* Not meeting all of the above.","75 Years",{"count":433,"type":20},80,[23],"To assess in women with triple-negative breast cancer receiving neo-adjuvant chemotherapy the effects of an intense physical exercise program (intervention group) on physical capacity, compared with a control group not meeting the minimum exercise recommendations of the World Health Organization (WHO).",[437],"Physical Exercise",[28,439,440],"high interval training","resistance exercise","2024-06-26",{"date":416,"type":37},{"date":444,"type":37},"2020-01-01",{"date":168,"type":20},{"name":43,"class":44},{"id":448,"slug":449,"hasResults":11,"nctId":450,"briefTitle":451,"officialTitle":452,"acronym":4,"eligibilityCriteria":453,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":4,"enrollmentInfo":454,"targetDuration":4,"studyType":321,"phases":4,"briefSummary":456,"conditions":457,"keywords":463,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":468,"lastUpdatePostDateStruct":469,"startDateStruct":471,"completionDateStruct":473,"leadSponsor":475,"locationsCount":45},"100534127","continuous-subcutaneous-glucose-monitoring-in-critical-patients-100534127","NCT06234787","Continuous Subcutaneous Glucose Monitoring in Critical Patients","Continuous Subcutaneous Glucose Monitoring: A Descriptive Study of Its Use in Critical Patients","Inclusion Criteria:\n\n* The study will be conducted in patients admitted to the ICU of HLA Moncloa Hospital over four years. Patients admitted to the ICU, undergoing insulin treatment, and having a CGM sensor.\n* Patients who sign the voluntary consent to participate in the study (Annex 2). If the participant is not in full physical or intellectual capacity to provide their signature on the informed consent, the responsible investigator will request such consent from their direct family member or the person legally designated to make decisions on their behalf regarding health matters. This measure is taken to ensure that the participant\\'s rights are respected, and the integrity of the consent process is maintained, even in situations where their decision-making capacity may be compromised.\n\nExclusion Criteria:\n\n* Patients from whom information on CGM cannot be obtained for technical reasons.",{"count":455,"type":20},245,"This is a single-center, observational, descriptive, longitudinal, and prospective study This study aims to determine the cumulative incidence during admission and the incidence rate of potential hypoglycemic events (defined as subcutaneous glucose \\\u003C80 mg\u002FdL detected by CGM) in patients admitted to the Intensive Care Unit (ICU) of HLA Moncloa Hospital over four years of follow-up. The study also aims to document the occurrences of hypoglycemic events, describe the characteristics of patients receiving CGM sensors, and outline the actions taken as a result of detecting potential hypoglycemic events",[458,459,460,461,462],"Hyperglycemia","Hypoglycemia","Diabetes","Critical Care","Critically Ill Patients",[464,465,466,467],"continuous subcutaneous glucose monitoring","critical care","intensive care","hypoglycemia","2024-02-01",{"date":470,"type":37},"2024-02-05",{"date":472,"type":37},"2023-11-30",{"date":474,"type":20},"2027-12-01",{"name":43,"class":44},""]