[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad Santo Tomas, Chile\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":79},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":5},"100614326","effects-of-resistance-and-dual-task-training-on-physical-oculomotor-and-executive-functions-in-older-adults-with-mci-100614326",false,"NCT07278141","Effects of Resistance and Dual-Task Training on Physical, Oculomotor, and Executive Functions in Older Adults With MCI","Study Protocol: Effects of Combined Resistance Training and Dual-Task Interventions on Physical, Oculomotor, and Executive Functions in Older Adults With Mild Cognitive Impairment. A Randomized Controlled Trial","Inclusion Criteria:\n\n* Men and women aged 60 years or older\n* Score between 10 and 25 points on the Montreal Cognitive Assessment (MoCA) scale\n* Provide informed consent\n\nExclusion Criteria:\n\n* Visual or auditory disability that impedes communication\n* Previous diagnosis of dementia\n* Wheelchair use\n* Epilepsy\n* Progressive or terminal illness\n* Depression\n* History of alcoholism\n* Musculoskeletal or cardiovascular contraindications for strength exercises\n* Color blindness\n* Dyslexia\n* Severe mental or cognitive problems supported by medical reports","ALL","60 Years","90 Years",{"count":20,"type":21},66,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to determine the effect of a combined therapeutic intervention program with anaerobic exercises (resistance exercises) and dual tasks on the physical, oculomotor, and executive functions of older adults with mild cognitive impairment.\n\nThe main questions it aims to answer are:\n\n• How effective will a therapeutic intervention program combining resistance exercises with dual tasks be in improving the physical, oculomotor, and executive functions of older adults with mild cognitive impairment living in the community? Researchers will compare the effectiveness of a resistance exercise training program combined with dual tasks versus a resistance-only exercise training program to see if it improves the physical, oculomotor, and executive functions of older adults with mild cognitive impairment\n\nParticipants Will:\n\n* Receive resistance exercises, resistance exercises combined with dual tasks. or the standard health care. The intervention programs will consist of 3 weekly sessions over 8 weeks.\n* Before the start and after the completion of the programs, they will be evaluated using a battery of tests. This includes sociodemographic and general health background, physical fitness tests, as well as assessments of executive functions and oculomotor Saccadic movements and anti-saccadic error.\n* be required to sign a consent form.",[27,28,29],"Physical Function","Executive Function (Cognition)","Saccadic Eye Movements",[31,32,33,34,35,36,37,38],"combination training","Dual-Task","Physical-Cognitive Training","aging","older adult","Timed Up & Go","executive function","Resistance Training","NOT_YET_RECRUITING","2025-11-28",{"date":42,"type":43},"2025-12-11","ACTUAL",{"date":45,"type":21},"2026-01-17",{"date":47,"type":21},"2026-12-17",{"name":49,"class":50},"Universidad Santo Tomas, Chile","OTHER",{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":58,"maxAge":4,"enrollmentInfo":59,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":4},"100553198","effectiveness-of-exercise-plus-pain-neuroscience-education-on-brain-function-in-knee-osteoarthritis-100553198","NCT06482970","Effectiveness of Exercise Plus Pain Neuroscience Education on Brain Function in Knee Osteoarthritis","Brain Function, Clinical and Psychosocial Outcomes After Neuromuscular Exercise Plus Pain Neuroscience Education Intervention in Patients With Chronic Pain Due to Knee Osteoarthritis. A Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n* women and men at least 45 years old radiologically diagnosed with unilateral or bilateral KOA (Kellgren-Lawrence 1-3 grading scale)\n* pain duration greater than three months\n\nExclusion Criteria:\n\n* Patients who have received physical therapy or other conservative therapy in the previous three months and those who have a history of major knee trauma and surgery in the last six months\n* cardiac pathology\n* structural use of psychoactive medications, such as antipsychotics, antidepressants, antiepileptics, and anxiolytics, during the past year\n* neurological diseases\n* other musculoskeletal clinical conditions that generate pain","45 Years",{"count":60,"type":21},57,[24],"A three-arm randomized controlled trial will be conducted. Fifty-nine participants with KOA will be recruited in a 1:1:1 ratio. Assessor, and statistician will be blinded to group allocation. One experimental group (n=19) will receive NME plus PNE, the other experimental group (n=19) will receive isolated NME and the control group (n=19) will continue with usual care. The PNE will be adapted to the context of the participants. Outcome measures will be brain activity, pressure pain threshold, pain intensity, disability, fear-avoidance beliefs, self-efficacy, and pain catastrophizing. Outcome measures will be evaluated pre-intervention, immediately post-intervention, and four-month post-intervention.\n\nThe investigators hypothesize that there will be significant differences in favor of the NME plus PNE intervention group.",[64],"Knee Osteoarthritis",[66,67,68,69,70],"Neuromuscular exercise","Pain neuroscience education","Knee osteoarthritis","Chronic pain","Physical therapy","2024-06-25",{"date":73,"type":43},"2024-07-01",{"date":75,"type":21},"2025-03-15",{"date":77,"type":21},"2025-12-30",{"name":49,"class":50},""]