[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad Simón Bolívar\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":81},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":4},"100641306","catheter-redosing-of-autonomic-neural-blockade-after-sleeve-gastrectomy-100641306",false,"NCT07655908","Catheter Redosing of Autonomic Neural Blockade After Sleeve Gastrectomy","Targeted Temporary In Situ Catheter Redosing of Autonomic Neural Blockade for Breakthrough Symptoms After Laparoscopic Sleeve Gastrectomy","Inclusion Criteria:\n\nPatients undergoing elective laparoscopic sleeve gastrectomy with one or more of the following risk factors for breakthrough visceral\u002Fautonomic symptoms:\n\n* Female sex age \\\u003C30 years\n* Prior history of severe postoperative pain after abdominal surgery\n* Prior history of significant postoperative nausea\u002Fvomiting\n* History of opioid intolerance or significant opioid-related adverse effects\n* Allergy\u002Fintolerance to multiple postoperative analgesics\u002Fantiemetics\n* Concomitant hiatal hernia repair\n* Surgeon's judgment of elevated visceral symptom risk based on prior institutional experience\n\nExclusion Criteria:•\n\n* Contraindication to local anesthetics or dexamethasone\n* Chronic opioid dependence\n* Severe psychiatric or cognitive impairment limiting symptom assessment\n* Pregnancy\n* Conversion to open surgery\n* Inability or unwillingness to comply with the postoperative reporting protocol.","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","Postoperative visceral pain and autonomic symptoms after laparoscopic sleeve gastrectomy may reappear earlier in selected high-risk patients despite standard intraoperative autonomic neural blockade (ANB). Temporary in situ catheter placement permits postoperative ANB redosing when breakthrough visceral symptoms occur.\n\nThis prospective single-arm observational study will evaluate the feasibility, safety, and clinical effectiveness of temporary ANB catheter placement and selective postoperative redosing in high-risk patients undergoing laparoscopic sleeve gastrectomy.",[26,27],"Pain, Acute Post-Operative","Nausea and Vomiting, Postoperative",[29,30,31,32,33],"Autonomic neural blockade","visceral pain","postoperative nausea and vomiting","re-dosing","temporal catheter","NOT_YET_RECRUITING","2026-06-13",{"date":37,"type":38},"2026-06-18","ACTUAL",{"date":40,"type":20},"2026-06-15",{"date":42,"type":20},"2027-02",{"name":44,"class":45},"Universidad Simón Bolívar","OTHER",{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":58,"conditions":59,"keywords":65,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":5},"100573993","phase-4-intraoperative-autonomic-blockade-for-laparoscopic-cholecystectomy-100573993","NCT06753500","Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy","Intraoperative Autonomic Blockade to Prevent Early Postoperative Pain After Laparoscopic Cholecystectomy: A Double-Blind, Randomized Controlled Trial","ANB","Inclusion Criteria:\n\n* Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or without cholecystitis.\n\nExclusion Criteria:\n\n* Associated biliary pathologies (e.g., biliary pancreatitis, cholangitis).\n\n  * Additional procedures, such as formal bile duct exploration. Conversion to an open approach\n  * Anesthesia or Surgical complications that require intensive care unit\n* Allergies to local anesthetics",{"count":55,"type":20},60,[57],"PHASE4","This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.",[60,61,62,63,64],"Visceral Pain","Analgesia","Opioid Use","Postoperative Nausea","Postoperative Vomiting",[66,67,68,69,70,71],"autonomic neural blockade,","Visceral pain","postoperative nausea","Postoperative vomiting","analgesic consumption","opioid use","RECRUITING","2025-01-25",{"date":75,"type":38},"2025-01-28",{"date":77,"type":38},"2025-01-15",{"date":79,"type":20},"2025-11-04",{"name":44,"class":45},""]