[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad de Colima\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":118},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,85],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":4},"100623520","effects-of-hiit-and-mict-training-on-cardiorespiratory-fitness-testosteronecortisol-ratio-and-mental-health-in-young-adults-100623520",false,"NCT07397702","Effects of HIIT and MICT Training on Cardiorespiratory Fitness, Testosterone\u002FCortisol Ratio, and Mental Health in Young Adults","Effects of HIIT and MICT Training on Cardiorespiratory Fitness, Testosterone\u002FCortisol Ratio, and Mental Health in Young Adults: an 8-week Randomized Clinical Trial","Inclusion criteria:\n\n* Men and women aged 18 to 21.\n* Lead a sedentary or moderately active lifestyle (IPAQ ≤600 METs-min\u002Fweek).\n* Subjects diagnosed by a physician as fit for physical exercise.\n* Informed consent form signed by the study subjects.\n\nExclusion criteria:\n\n* Subjects with any motor disability.\n* Pregnant women.\n* Subjects with metabolic disorders.\n* Subjects with chronic respiratory diseases such as asthma, emphysema, or cancer, obstructive pulmonary disease.\n* Subjects with high blood pressure or arrhythmia.\n* Failure to sign the informed consent form.\n* Subjects who are in a high-performance physical training program.\n* Women with irregular menstrual cycles who take contraceptive medication to regulate their menstrual cycle.\n* Consumption of caffeine, alcohol, and tobacco or use of electronic cigarettes.\n* Subjects with a cyclical diagnosis of anxiety and depression by a specialist.\n* Frequent consumption of alcoholic beverages (more than 7 drinks per week for women and more than 14 drinks per week for men) or a history of excessive alcohol consumption.\n* Subjects who consume dietary supplements (caffeine, nitric oxide precursors, beta-alanine, creatine, sodium bicarbonate, or L-carnitine).\n\nElimination criteria:\n\n* Voluntary withdrawal from the study.\n* Attendance at less than 80% of intervention sessions.\n* Incomplete measurement schedule or insufficient sample size.\n* Joint or muscle injuries caused by the training program.\n* Overtraining syndrome.",true,"ALL","18 Years","21 Years",{"count":21,"type":22},76,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study will use a randomized, double-blind clinical trial to evaluate the effects of eight-week HIIT and MICT exercise programs on cardiorespiratory fitness, the testosterone\u002Fcortisol ratio, and mental health in 68 healthy, moderately active young adults aged 18 to 21. Participants will be assigned to parallel groups based on their sex and training type (HIIT men, HIIT women, MICT men, MICT women). The key metrics will be measured both before and after the intervention period to assess the impact of the different training regimens.",[28],"Exercise",[30,31,32,33,34,35],"High-Intensity Interval Training","Aerobic Exercise","Testosterone","Cortisol","Anxiety Disorders","Depressive Disorder","NOT_YET_RECRUITING","2026-02-04",{"date":39,"type":40},"2026-02-09","ACTUAL",{"date":42,"type":22},"2026-05-25",{"date":44,"type":22},"2026-08-07",{"name":46,"class":47},"Universidad de Colima","OTHER",{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":16,"sex":17,"minAge":56,"maxAge":18,"enrollmentInfo":57,"targetDuration":4,"studyType":23,"phases":59,"briefSummary":62,"conditions":63,"keywords":67,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},"100536756","phase-1-exploring-treatments-for-childrens-abdominal-pain-comparing-trimebutine-and-probiotics-100536756","NCT06268964","Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics","Comparative Effect of Trimebutine and Probiotics on Functional Abdominal Pain Disorders (FAPD) in Children: Randomized Clinical Trial (RCT)","FAPD_RCT","Inclusion Criteria:\n\n* Pediatric patients from 4 to 18 years old.\n* Meeting the Rome IV criteria for any of the Functional Abdominal Pain Disorders (Functional Dyspepsia, Irritable Bowel Syndrome, Abdominal Migraine or Functional Abdominal Pain Not Otherwise Specified)\n* Having the informed consent signed by the parents or legal guardians of the minor.\n\nExclusion Criteria:\n\n* Patients presenting abdominal pain of organic cause.\n* Immunosuppressed patients.\n* Patients with previous hypersensitivity to the study drug.\n\nElimination Criteria:\n\n* Voluntary withdrawal from the study.\n* Patients not adhering to treatment (less than 80%)\n* Patients participating in another study simultaneously.\n* Patients being treated by another doctor simultaneously.","4 Years",{"count":58,"type":22},82,[60,61],"PHASE1","PHASE2","The goal of this clinical trial is to test the effectiveness of trimebutine and probiotics in treating Functional Abdominal Pain Disorders (FAPD) in a pediatric population. The main questions it aims to answer are: Is trimebutine effective in reducing the symptoms of FAPD in children? Are probiotics effective in reducing the symptoms of FAPD in children? Participants will be randomly assigned to one of three treatment groups (trimebutine\u002Fprobiotics, probiotics\u002Fplacebo, or trimebutine\u002Fplacebo). Undergo measurements for pain and other relevant metrics at the start of the study, after 4 weeks, and after 8 weeks.\n\nResearchers will compare the trimebutine\u002Fprobiotics group to the probiotics\u002Fplacebo and the trimebutine\u002Fplacebo groups to see if there are significant differences in the efficacy of these treatments in reducing symptoms of FAPD in children.",[64,65,66],"Functional Abdominal Pain Syndrome","Functional Gastrointestinal Disorders","Irritable Bowel Syndrome Variant of Childhood",[68,69,70,71,72,73,74],"functional abdominal pain","randomized clinical trial","placebo","double-blind","trimebutine","Lactobacillus rhamnosus","pediatrics","RECRUITING","2024-08-13",{"date":78,"type":40},"2024-08-16",{"date":80,"type":22},"2024-09-01",{"date":82,"type":22},"2025-06-30",{"name":46,"class":47},1,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":23,"phases":96,"briefSummary":97,"conditions":98,"keywords":105,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":113,"completionDateStruct":115,"leadSponsor":117,"locationsCount":84},"100558748","exploring-physical-exercise-for-the-regulation-and-control-of-metabolic-disorders-in-college-students-100558748","NCT06555159","Exploring Physical Exercise for the Regulation and Control of Metabolic Disorders in College Students.","EFFECT OF AN AEROBIC EXERCISE PROGRAM ON METABOLIC DISORDERS LEVELS IN HIGHER EDUCATION STUDENTS AT THE UNIVERSITY OF COLIMA, RANDOMIZED CLINICAL TRIAL.","(EPE_RCTMCS)","Inclusion Criteria:\n\n* University of Colima students linked to the central campus.\n* Students aged between 18 and 25 years old.\n* Authorization to participate in the project with a signed informed consent.\n* Suffer from at least one of the parameters of metabolic disorders or cardiovascular risk (Hyperglycemia, decreased DHL, elevated triglycerides, abdominal obesity or hypertension) following the clinical assessment (Considering the criteria established by the ADA and ATPIII).\n\nExclusion Criteria:\n\n* Motor limitations that may hinder the performance of physical exercise.\n* Pregnancy or lactation.\n* High Vigorous Physical Activity Level according to the IPA-Q.\n* To be currently under pharmacological treatment to manage altered metabolic levels.\n\nELIMINATION CRITERIA\n\n* Musculoskeletal injuries during the study period.\n* Unforeseen Medical Events: Unexpected medical situations that could influence study results, such as hospitalizations, serious illnesses, or surgeries.\n* Non-Compliance with Follow-Up: Subjects failing to meet a minimum of 80% (19 out of 24 sessions) of the stipulated physical conditioning program time.\n* Initiation of clinical treatment that may affect protocol results, such as medications that reduce alterations.\n* Participants who voluntarily withdraw from the study.","25 Years",{"count":95,"type":22},48,[25],"This clinical trial objective is to evaluate the effect of an aerobic physical exercise program on reducing triglycerides, blood pressure, abdominal obesity, altered glucose levels, and the increase in HDL in college-level students at the University of Colima. It will try to answer whether aerobic physical exercise reduces metabolic disorders (altered blood pressure and glucose levels, abdominal obesity, and increased HDL). A simple randomized clinical trial will be conducted with a sample of 48 voluntary students from the University of Colima, divided into two groups of 24 people (Control group -A-, will perform aerobic physical exercise, which will be walking at 57% to 76% of HRmax; and Experimental Group -B-, will undergo an aerobic physical exercise (APE) program involving jogging, swimming, and static cycling, with a progressive intensity, which will start at 57%-63% of the maximum heart rate (HRmax) in the first 4 weeks of the study, and will increase to 64% -76% in the final four weeks, fulfilling the principle of progressive overload).\n\nResearchers will compare the results of both groups to confirm the effectiveness of the planned aerobic physical exercise in reducing these risks.",[99,100,101,102,103,104],"Metabolic Disorders","Abdominal Obesity","Blood Pressure Disorders","Hypertriglyceridemia","Hyperglycemia","HDL-Deficiency",[28,106,107,108,109],"Obesity","HDL","Triglycerides","Hypertension","2024-08-12",{"date":112,"type":40},"2024-08-15",{"date":114,"type":22},"2024-09",{"date":116,"type":22},"2025-06",{"name":46,"class":47},""]