[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Universidad de Santiago de Chile\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100639519","high-flow-nasal-cannula-on-exercise-tolerance-in-heart-failure-patients-undergoing-cardiac-rehabilitation-100639519",false,"NCT07613762","High-Flow Nasal Cannula on Exercise Tolerance in Heart Failure Patients Undergoing Cardiac Rehabilitation","Effect of High-Flow Nasal Cannula Use on Exercise Tolerance and Physical Performance in Heart Failure Patients Enrolled in a Cardiac Rehabilitation Program: A Randomized Crossover Trial","Inclusion Criteria:\n\n* Age 18 years or older\n* Medical diagnosis of heart failure (documented in clinical record or referral)\n* Electrocardiogram performed within the last 6 months\n* Functional capacity class II or III according to the New York Heart Association (NYHA) classification\n* Stable pharmacological treatment\n* Stable and controlled comorbidities\n* Available to complete two evaluation sessions\n* Able and willing to provide written informed consent\n\nExclusion Criteria:\n\n* Diagnosis of respiratory disease (chronic obstructive pulmonary disease, interstitial lung disease, or pulmonary hypertension)\n* Myocardial infarction within the past 3 months\n* Hospitalization due to heart failure within the past 4 weeks\n* Cognitive impairment or inability to follow the study protocol\n* Neuromuscular or osteoarticular conditions that limit treadmill test performance","ALL","18 Years",{"count":19,"type":20},28,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this clinical trial is to learn if a high-flow nasal cannula (HFNC) - a device that delivers warm, humidified air through a small tube placed in the nostrils - can improve exercise tolerance in adults with heart failure (HF) who are entering a cardiac rehabilitation program. The main questions it aims to answer are: Can HFNC help people with heart failure exercise for a longer time during a treadmill test? and does HFNC lower how hard people feel they are working during exercise?\n\nResearchers will compare exercise performance with HFNC to exercise performance without HFNC to see if HFNC helps people with HF tolerate exercise better. Participants will:\n\nComplete two treadmill exercise tests, one with HFNC and one without, in a randomly assigned order.\n\nWait 48 to 72 hours between the two tests to allow full recovery. Have their heart rate, blood pressure, oxygen level, and breathing rate measured before and after each test.",[26,27,28],"Heart Failure","Exercise Tolerance (Measured in Minutes)","Cardiac Rehabilitation",[30,31,26,28,32,33,34,35,36,37],"High-Flow Nasal Cannula","HFNC","Exercise Tolerance","Incremental Treadmill Test","Crossover Trial","Dyspnea","Physical Performance","Cardiopulmonary Rehabilitation","NOT_YET_RECRUITING","2026-05-30",{"date":41,"type":42},"2026-06-02","ACTUAL",{"date":44,"type":20},"2026-06-01",{"date":46,"type":20},"2027-03",{"name":48,"class":49},"Universidad de Santiago de Chile","OTHER",""]